HK1043059B - 腫瘤壞死因子拮抗劑及其在子宮內膜異位症上的應用 - Google Patents

腫瘤壞死因子拮抗劑及其在子宮內膜異位症上的應用

Info

Publication number
HK1043059B
HK1043059B HK02104822.4A HK02104822A HK1043059B HK 1043059 B HK1043059 B HK 1043059B HK 02104822 A HK02104822 A HK 02104822A HK 1043059 B HK1043059 B HK 1043059B
Authority
HK
Hong Kong
Prior art keywords
endometriosis
necrosis factor
tumor necrosis
factor antagonists
antagonists
Prior art date
Application number
HK02104822.4A
Other languages
English (en)
Other versions
HK1043059A1 (en
Inventor
F‧博雷利列
M‧德安東尼奧
F‧馬爾泰利
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8237393&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1043059(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Publication of HK1043059A1 publication Critical patent/HK1043059A1/xx
Publication of HK1043059B publication Critical patent/HK1043059B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK02104822.4A 1999-01-22 2002-06-28 腫瘤壞死因子拮抗劑及其在子宮內膜異位症上的應用 HK1043059B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99101194A EP1022027A1 (en) 1999-01-22 1999-01-22 Tumor necrosis factor antagonists and their use in endometriosis
PCT/IB2000/000052 WO2000043031A1 (en) 1999-01-22 2000-01-19 Tumor necrosis factor antagonists and their use in endometriosis

Publications (2)

Publication Number Publication Date
HK1043059A1 HK1043059A1 (en) 2002-09-06
HK1043059B true HK1043059B (zh) 2005-11-18

Family

ID=8237393

Family Applications (2)

Application Number Title Priority Date Filing Date
HK02104822.4A HK1043059B (zh) 1999-01-22 2002-06-28 腫瘤壞死因子拮抗劑及其在子宮內膜異位症上的應用
HK06105041.2A HK1082690A1 (en) 1999-01-22 2006-04-27 Tumor necrosis factor antagonists and their use in endometriosis

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK06105041.2A HK1082690A1 (en) 1999-01-22 2006-04-27 Tumor necrosis factor antagonists and their use in endometriosis

Country Status (30)

Country Link
US (2) US6663865B1 (zh)
EP (2) EP1022027A1 (zh)
JP (1) JP4601176B2 (zh)
KR (2) KR20060128056A (zh)
CN (2) CN100594932C (zh)
AR (1) AR022251A1 (zh)
AT (1) ATE242002T1 (zh)
AU (1) AU771964B2 (zh)
BG (1) BG65556B1 (zh)
BR (1) BR0008182A (zh)
CA (1) CA2356737C (zh)
CZ (1) CZ302866B6 (zh)
DE (1) DE60003152T2 (zh)
DK (1) DK1143997T3 (zh)
EA (1) EA003927B1 (zh)
EE (1) EE05543B1 (zh)
ES (1) ES2200808T3 (zh)
HK (2) HK1043059B (zh)
HU (1) HU226149B1 (zh)
IL (2) IL144413A0 (zh)
NO (1) NO328814B1 (zh)
NZ (1) NZ512585A (zh)
PL (1) PL204713B1 (zh)
PT (1) PT1143997E (zh)
SI (1) SI1143997T1 (zh)
SK (1) SK287313B6 (zh)
TR (1) TR200102107T2 (zh)
UA (1) UA78483C2 (zh)
WO (1) WO2000043031A1 (zh)
ZA (1) ZA200105263B (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60224004T2 (de) * 2001-01-29 2009-07-23 Laboratoires Serono S.A., Coinsins Verwendung von il-18 hemmern zur behandlung und/oder prävention von herzkrankheiten
US20060073141A1 (en) * 2001-06-28 2006-04-06 Domantis Limited Compositions and methods for treating inflammatory disorders
US20050271663A1 (en) * 2001-06-28 2005-12-08 Domantis Limited Compositions and methods for treating inflammatory disorders
EP1709965A3 (en) 2001-07-11 2006-12-27 Boehringer Ingelheim Pharmaceuticals, Inc. Methods of treating cytokine mediate diseases
US7082134B1 (en) * 2002-01-18 2006-07-25 Juniper Networks, Inc. Redirect checking in a network device
US20070298041A1 (en) * 2002-06-28 2007-12-27 Tomlinson Ian M Ligands That Enhance Endogenous Compounds
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor
AU2003212569A1 (en) * 2003-02-07 2004-08-30 Ambros Valentin Huber Use of human chorionic gonadotropin in the treatment in the treatment of symptoms caused by endometriosis
US7749999B2 (en) 2003-09-11 2010-07-06 Itherx Pharmaceuticals, Inc. Alpha-ketoamides and derivatives thereof
GB0327112D0 (en) 2003-11-21 2003-12-24 Clincial Designs Ltd Dispenser and reservoir
GB0408449D0 (en) 2004-04-15 2004-05-19 Banerjee Subhasis Diagnostic and therapeutic applications of soluble lhcge protein
CA2565801A1 (en) * 2004-05-28 2005-12-15 Applied Research Systems Ars Holding N.V. Use of il-17 in the treatment of fertility-related disorders
US20060045902A1 (en) * 2004-09-01 2006-03-02 Serbousek Jon C Polymeric wrap for in vivo delivery of osteoinductive formulations
EP2468282A3 (en) * 2005-07-12 2012-09-12 DMI Biosciences, Inc. Methods and products for treatment of diseases
CA2683801A1 (en) * 2007-06-06 2008-12-11 Domantis Limited Polypeptides, antibody variable domains and antagonists
PL2425839T3 (pl) 2009-06-22 2015-03-31 Ampio Pharmaceuticals Inc Sposób leczenia chorób
SG10201403388SA (en) * 2009-06-22 2014-10-30 Ampio Pharmaceuticals Inc Methods and products for treatment of diseases
JP2016503794A (ja) 2012-12-19 2016-02-08 アンピオ ファーマシューティカルズ，インコーポレイテッド 疾患の治療のための方法
CA2978449A1 (en) 2015-03-02 2016-09-09 180 Therapeutics Lp Method of treating a localized fibrotic disorder using an il-33 antagonist

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5037805A (en) * 1989-03-20 1991-08-06 The Salk Institute For Biological Studies Methods of contraception
DK1097945T3 (da) * 1991-03-18 2007-11-05 Univ New York Monoklonale og kimære antistoffer, der er specifikke for human tumornekrosefaktor
US20040120952A1 (en) * 2000-08-07 2004-06-24 Centocor, Inc Anti-TNF antibodies and peptides of human tumor necrosis factor
KR100232688B1 (ko) * 1992-09-15 1999-12-01 스코트 쥐. 홀퀴스트 종양 괴사 인자 길항제를 함유하는 tnf-의존성 염증 치료용 제약 조성물
US5389657A (en) * 1993-02-01 1995-02-14 Free Radical Sciences Corporation Method for treating infertility
IL111125A0 (en) * 1994-05-11 1994-12-29 Yeda Res & Dev Soluble oligomeric tnf/ngf super family ligand receptors and their use
US5747532A (en) * 1995-11-21 1998-05-05 Medinox, Inc. Combinational therapeutic methods employing nitric oxide scavengers and compositions useful therefor
US6090382A (en) * 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
US5710247A (en) * 1996-03-19 1998-01-20 Abbott Laboratories Process and intermediates for the synthesis of LHRH antagonists
GB9607120D0 (en) * 1996-04-04 1996-06-12 Chiroscience Ltd Compounds
GB9616643D0 (en) * 1996-08-08 1996-09-25 Chiroscience Ltd Compounds
WO1998023284A1 (en) * 1996-11-27 1998-06-04 Immunex Corporation Method of regulating nitric oxide production
US6514977B1 (en) * 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors

Also Published As

Publication number Publication date
PL350002A1 (en) 2002-10-21
HUP0105103A3 (en) 2004-08-30
ZA200105263B (en) 2002-06-26
PT1143997E (pt) 2003-10-31
CA2356737C (en) 2010-03-23
PL204713B1 (pl) 2010-02-26
EP1022027A1 (en) 2000-07-26
EE05543B1 (et) 2012-06-15
SK287313B6 (sk) 2010-06-07
BG65556B1 (bg) 2008-12-30
DE60003152T2 (de) 2004-03-25
EP1143997B1 (en) 2003-06-04
UA78483C2 (en) 2007-04-10
IL144413A (en) 2009-05-04
NO328814B1 (no) 2010-05-18
IL144413A0 (en) 2002-05-23
KR20010101397A (ko) 2001-11-14
AU771964B2 (en) 2004-04-08
SK10292001A3 (sk) 2001-12-03
AR022251A1 (es) 2002-09-04
WO2000043031A1 (en) 2000-07-27
US6663865B1 (en) 2003-12-16
HK1082690A1 (en) 2006-06-16
CN1212152C (zh) 2005-07-27
HK1043059A1 (en) 2002-09-06
US20040057954A1 (en) 2004-03-25
AU1997300A (en) 2000-08-07
BR0008182A (pt) 2001-11-06
DK1143997T3 (da) 2003-09-15
KR20060128056A (ko) 2006-12-13
JP4601176B2 (ja) 2010-12-22
CA2356737A1 (en) 2000-07-27
HUP0105103A2 (hu) 2002-04-29
EA003927B1 (ru) 2003-10-30
CZ20012656A3 (cs) 2002-02-13
SI1143997T1 (en) 2003-12-31
CN1698894A (zh) 2005-11-23
EA200100799A1 (ru) 2001-12-24
EP1143997A1 (en) 2001-10-17
ES2200808T3 (es) 2004-03-16
NZ512585A (en) 2003-08-29
BG105691A (en) 2002-02-28
NO20013577D0 (no) 2001-07-19
DE60003152D1 (de) 2003-07-10
HU226149B1 (en) 2008-05-28
TR200102107T2 (tr) 2001-12-21
ATE242002T1 (de) 2003-06-15
NO20013577L (no) 2001-08-29
JP2002535284A (ja) 2002-10-22
EE200100378A (et) 2002-10-15
KR100685106B1 (ko) 2007-02-22
CN1337883A (zh) 2002-02-27
CN100594932C (zh) 2010-03-24
CZ302866B6 (cs) 2011-12-21

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130119