ZA200007321B - Methods and compositions useful for modulation of angiogenesis using tyrosine kinase Src. - Google Patents

Methods and compositions useful for modulation of angiogenesis using tyrosine kinase Src.

Info

Publication number
ZA200007321B
ZA200007321B ZA200007321A ZA200007321A ZA200007321B ZA 200007321 B ZA200007321 B ZA 200007321B ZA 200007321 A ZA200007321 A ZA 200007321A ZA 200007321 A ZA200007321 A ZA 200007321A ZA 200007321 B ZA200007321 B ZA 200007321B
Authority
ZA
South Africa
Prior art keywords
angiogenesis
methods
src protein
nucleic acids
modulation
Prior art date
Application number
ZA200007321A
Other languages
English (en)
Inventor
David A Cheresh
Pamela L Schwartzberg
Brian Eliceiri
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of ZA200007321B publication Critical patent/ZA200007321B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
ZA200007321A 1998-05-29 2000-12-08 Methods and compositions useful for modulation of angiogenesis using tyrosine kinase Src. ZA200007321B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8722098P 1998-05-29 1998-05-29

Publications (1)

Publication Number Publication Date
ZA200007321B true ZA200007321B (en) 2002-03-08

Family

ID=22203825

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200007321A ZA200007321B (en) 1998-05-29 2000-12-08 Methods and compositions useful for modulation of angiogenesis using tyrosine kinase Src.

Country Status (24)

Country Link
US (1) US7585841B2 (hu)
EP (1) EP1082415B1 (hu)
JP (1) JP4806487B2 (hu)
KR (1) KR20010085261A (hu)
CN (1) CN1304567C (hu)
AT (1) ATE506073T1 (hu)
AU (1) AU762955C (hu)
BR (1) BR9910787A (hu)
CA (1) CA2330025C (hu)
CZ (1) CZ302918B6 (hu)
DE (1) DE69943374D1 (hu)
DK (1) DK1082415T3 (hu)
ES (1) ES2361659T3 (hu)
HK (1) HK1041289A1 (hu)
HU (1) HU227985B1 (hu)
MX (1) MXPA00011821A (hu)
NO (1) NO327610B1 (hu)
PT (1) PT1082415E (hu)
RU (1) RU2222342C2 (hu)
SK (1) SK287330B6 (hu)
TR (1) TR200100430T2 (hu)
UA (1) UA75565C2 (hu)
WO (1) WO1999061590A1 (hu)
ZA (1) ZA200007321B (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999061590A1 (en) * 1998-05-29 1999-12-02 The Scripps Research Institute Methods and compositions useful for modulation of angiogenesis using tyrosine kinase src
US6685938B1 (en) * 1998-05-29 2004-02-03 The Scripps Research Institute Methods and compositions useful for modulation of angiogenesis and vascular permeability using SRC or Yes tyrosine kinases
US20030130209A1 (en) * 1999-12-22 2003-07-10 Cheresh David A. Method of treatment of myocardial infarction
US6297258B1 (en) * 1998-09-29 2001-10-02 American Cyanamid Company Substituted 3-cyanoquinolines
JP2003518077A (ja) * 1999-12-22 2003-06-03 ザ・スクリプス・リサーチ・インステイチユート 血管形成および血管透過性の調節剤および阻害剤
US7485414B2 (en) 2002-08-30 2009-02-03 Rigel Pharmaceuticals, Inc. Modulators of angiogenesis
US20080280987A1 (en) * 2006-08-31 2008-11-13 Desai Neil P Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases
WO2008054792A2 (en) * 2006-10-31 2008-05-08 University Of Toledo Na+/k+-atpase-specific peptide inhibitors/activators of src and src family kinases
DE102007037008B4 (de) * 2007-08-06 2015-09-10 Siemens Aktiengesellschaft Diagnosesubstanz zur Anwendung in einem Verfahren zur Bestimmung der Aggressivität eines Prostatatumors
US20120189701A1 (en) 2009-03-13 2012-07-26 Desai Neil P Combination therapy with thiocolchicine derivatives
RU2539859C2 (ru) * 2013-05-06 2015-01-27 Государственное научное учреждение Всероссийский научно-исследовательский институт орошаемого овощеводства и бахчеводства Российской академии сельскохозяйственных наук (ГНУ ВНИИОБ РАСХН) Способ производства цукатов из кабачков различной степени спелости

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
AU7432496A (en) * 1995-10-13 1998-05-11 Regents Of The University Of Minnesota Consolidated ligands with increased affinities and methods of use thereof
US6335010B1 (en) * 1996-11-08 2002-01-01 University Of California At San Diego Gene therapy in coronary angioplasty and bypass
WO1999061590A1 (en) * 1998-05-29 1999-12-02 The Scripps Research Institute Methods and compositions useful for modulation of angiogenesis using tyrosine kinase src
GB2341182A (en) * 1998-09-01 2000-03-08 Yamanouchi Uk Ltd Protein comprising amino acid sequences having SH3 domain binding activity and nuclear localisation activity

Also Published As

Publication number Publication date
AU762955B2 (en) 2003-07-10
WO1999061590A9 (en) 2000-03-09
EP1082415B1 (en) 2011-04-20
JP2002516344A (ja) 2002-06-04
TR200100430T2 (tr) 2002-05-21
CA2330025A1 (en) 1999-12-02
RU2222342C2 (ru) 2004-01-27
US20060009412A1 (en) 2006-01-12
HK1041289A1 (en) 2002-07-05
CZ20004435A3 (en) 2001-06-13
JP4806487B2 (ja) 2011-11-02
DK1082415T3 (da) 2011-06-14
PT1082415E (pt) 2011-07-04
MXPA00011821A (es) 2004-07-30
EP1082415A4 (en) 2003-07-09
HUP0102614A3 (en) 2005-11-28
AU762955C (en) 2005-03-24
DE69943374D1 (de) 2011-06-01
SK287330B6 (sk) 2010-07-07
NO20006026D0 (no) 2000-11-28
UA75565C2 (uk) 2006-05-15
CN1319131A (zh) 2001-10-24
NO327610B1 (no) 2009-08-31
HUP0102614A2 (hu) 2001-11-28
HU227985B1 (en) 2012-07-30
KR20010085261A (ko) 2001-09-07
AU4101399A (en) 1999-12-13
NO20006026L (no) 2001-01-24
CZ302918B6 (cs) 2012-01-18
US7585841B2 (en) 2009-09-08
ES2361659T3 (es) 2011-06-21
BR9910787A (pt) 2001-10-30
ATE506073T1 (de) 2011-05-15
SK18112000A3 (sk) 2001-09-11
WO1999061590A1 (en) 1999-12-02
CN1304567C (zh) 2007-03-14
EP1082415A1 (en) 2001-03-14
CA2330025C (en) 2009-03-17

Similar Documents

Publication Publication Date Title
GEP20063885B (en) Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use
DE69828408D1 (de) Naphthyridinone zur hemmung der durch protein-tyrosin-kinase und zellzyklus kinase hervorgerufenen zellvermehrung
CA2366932A1 (en) Cyclic protein tyrosine kinase inhibitors
AU2464601A (en) Tricyclic protein kinase inhibitors
IL125735A (en) Pharmaceutical compositions for the treatment of glaucoma comprising an inhibitor of serine-threonine kinase, tyrosine kinase or protein tyrosine phosphatase or an actin-disrupting compound
WO1999036550A3 (en) Human protease molecules
HUP0103520A3 (en) Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors and pharmaceutical compositions containing them
ZA9810219B (en) Benzothiazole protein tyrosine kinase inhibitors.
MX9709442A (es) Metodo y composiciones para la inhibicion de interacciones entre proteina adaptadora y tirosinquinasa.
BR0010220A (pt) Compostos de pirimidinona
AU762955C (en) Methods and compositions useful for modulation of angiogenesis using tyrosine kinase SRC
WO2003010291A3 (en) Treatment of immune disorders and b cell disorders
PL356815A1 (en) Angiogenesis and vascular permeability modulators and inhibitors
MXPA02010759A (es) Derivados del acido (2-oxindol-3-ilidenil) acetico y su uso como inhibidores de la proteina quinasa.
AU2001289034A1 (en) Novel pdes and uses thereof
WO2002017858A3 (en) Role of fosb in bone formation
AU2576901A (en) Agents and methods for the treatment of proliferative diseases
ATE362768T1 (de) Prb2/p130 peptidinhibitoren der cdk2 kinaseaktivität
WO2002088358A3 (en) Human fibroblast growth factor-related compositions
WO2001012213A3 (en) Ttp-related zinc finger domains and methods of use
IL151211A0 (en) Compositions useful for regulating parkin gene activity
ES2122912A1 (es) Inhibidores de metalocarboxipeptidasas y moleculas derivadas como agentes antitumorales.
WO2001096398A3 (en) Uncoupling proteins as targets for the treatment of heart failure
ZA987649B (en) Imidazoquinoxaline protein tyrosine kinase inhibitors.
UA31365A (uk) Спосіб симпатектомії дванадцятипалої кишки