AU2001289034A1 - Novel pdes and uses thereof - Google Patents
Novel pdes and uses thereofInfo
- Publication number
- AU2001289034A1 AU2001289034A1 AU2001289034A AU8903401A AU2001289034A1 AU 2001289034 A1 AU2001289034 A1 AU 2001289034A1 AU 2001289034 A AU2001289034 A AU 2001289034A AU 8903401 A AU8903401 A AU 8903401A AU 2001289034 A1 AU2001289034 A1 AU 2001289034A1
- Authority
- AU
- Australia
- Prior art keywords
- nucleic acid
- acid molecules
- novel pde
- novel
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Abstract
The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucleic acid molecules of the invention. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of novel PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of novel PDE proteins.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23244500P | 2000-09-12 | 2000-09-12 | |
US60/232,445 | 2000-09-12 | ||
US24050000P | 2000-10-12 | 2000-10-12 | |
US60/240,500 | 2000-10-12 | ||
PCT/US2001/028503 WO2002022661A2 (en) | 2000-09-12 | 2001-09-12 | NOVEL PDEs AND USES THEREOF |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001289034A1 true AU2001289034A1 (en) | 2002-03-26 |
Family
ID=26925998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001289034A Abandoned AU2001289034A1 (en) | 2000-09-12 | 2001-09-12 | Novel pdes and uses thereof |
Country Status (6)
Country | Link |
---|---|
US (2) | US7138259B2 (en) |
EP (1) | EP1317553B1 (en) |
AT (1) | ATE373717T1 (en) |
AU (1) | AU2001289034A1 (en) |
DE (1) | DE60130565D1 (en) |
WO (1) | WO2002022661A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE373717T1 (en) * | 2000-09-12 | 2007-10-15 | Univ Washington | PDE8A AND ITS USE |
EP1439221B1 (en) * | 2002-12-17 | 2007-01-24 | F. Hoffmann-La Roche Ag | PDE core construct |
WO2005023856A2 (en) * | 2003-09-05 | 2005-03-17 | University Of Bern | Cyclic nucleotide-specific phosphodiesterases from leishmania and uses thereof |
CN101579529A (en) | 2003-09-29 | 2009-11-18 | 托皮根药品公司 | Oligonucleotide compositions and method for treating disease including inflammatory conditions |
US20090105281A1 (en) * | 2006-04-27 | 2009-04-23 | Paul Epstein | Methods of treating inflammation |
WO2007134451A1 (en) | 2006-05-19 | 2007-11-29 | Topigen Pharmaceuticals Inc. | Oligonucleotides affecting expression of phosphodiesterases |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
EP4267573A1 (en) * | 2020-12-23 | 2023-11-01 | Genzyme Corporation | Deuterated colony stimulating factor-1 receptor (csf-1r) inhibitors |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4358535A (en) | 1980-12-08 | 1982-11-09 | Board Of Regents Of The University Of Washington | Specific DNA probes in diagnostic microbiology |
GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
DE3513168A1 (en) | 1985-04-12 | 1986-10-16 | Thomas 8000 München Dandekar | BIOSENSOR CONSISTING OF A SEMICONDUCTOR BASED ON SILICON OR CARBON-BASED (ELECTRONIC PART) AND NUCLEIN BASE (OR. OTHER BIOL. MONOMERS) |
US5194428A (en) | 1986-05-23 | 1993-03-16 | Worcester Foundation For Experimental Biology | Inhibition of influenza virus replication by oligonucleotide phosphorothioates |
US5110802A (en) | 1987-07-14 | 1992-05-05 | City Of Hope | Oligonucleotide phosphonates and method of inhibiting a human immunodeficiency virus in vitro utilizing said oligonucleotide phosphonates |
US5080548A (en) * | 1990-07-05 | 1992-01-14 | Columbia Trailer Co., Inc. | Trailer dumper |
US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
US5798246A (en) * | 1996-03-25 | 1998-08-25 | Incyte Pharmaceuticals, Inc. | Cyclic nucleotide phosphodiesterase |
US6080548A (en) * | 1997-11-19 | 2000-06-27 | Incyte Pharmaceuticals, Inc. | Cyclic nucleotide phosphodiesterases |
US5932465A (en) * | 1997-10-16 | 1999-08-03 | Icos Corporation | Phosphodiesterase 8A |
US5922595A (en) * | 1997-12-09 | 1999-07-13 | Incyte Pharmaceuticals, Inc. | Cyclic GMP phosphodiesterase |
US6686196B2 (en) * | 2000-05-03 | 2004-02-03 | University Of Washington | Recombinant, modified adenoviral vectors for tumor specific gene expression and uses thereof |
ATE373717T1 (en) * | 2000-09-12 | 2007-10-15 | Univ Washington | PDE8A AND ITS USE |
-
2001
- 2001-09-12 AT AT01968819T patent/ATE373717T1/en not_active IP Right Cessation
- 2001-09-12 DE DE60130565T patent/DE60130565D1/en not_active Expired - Lifetime
- 2001-09-12 EP EP01968819A patent/EP1317553B1/en not_active Expired - Lifetime
- 2001-09-12 US US10/380,437 patent/US7138259B2/en not_active Expired - Fee Related
- 2001-09-12 WO PCT/US2001/028503 patent/WO2002022661A2/en active IP Right Grant
- 2001-09-12 AU AU2001289034A patent/AU2001289034A1/en not_active Abandoned
-
2006
- 2006-06-01 US US11/421,658 patent/US7598067B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE373717T1 (en) | 2007-10-15 |
EP1317553B1 (en) | 2007-09-19 |
WO2002022661A3 (en) | 2003-03-13 |
WO2002022661A2 (en) | 2002-03-21 |
EP1317553A2 (en) | 2003-06-11 |
US20050058998A1 (en) | 2005-03-17 |
US7138259B2 (en) | 2006-11-21 |
DE60130565D1 (en) | 2007-10-31 |
US7598067B2 (en) | 2009-10-06 |
US20070116705A1 (en) | 2007-05-24 |
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