ZA200001593B - Use of 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz [B,E] oxepin-2-acetic acid for the manufacture of a medicament for treating non-allergic ophthalmic inflammatory disorders and for the prevention of ocular neovascularization. - Google Patents

Use of 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz [B,E] oxepin-2-acetic acid for the manufacture of a medicament for treating non-allergic ophthalmic inflammatory disorders and for the prevention of ocular neovascularization.

Info

Publication number
ZA200001593B
ZA200001593B ZA200001593A ZA200001593A ZA200001593B ZA 200001593 B ZA200001593 B ZA 200001593B ZA 200001593 A ZA200001593 A ZA 200001593A ZA 200001593 A ZA200001593 A ZA 200001593A ZA 200001593 B ZA200001593 B ZA 200001593B
Authority
ZA
South Africa
Prior art keywords
dimethylaminopropylidene
dihydrodibenz
oxepin
medicament
prevention
Prior art date
Application number
ZA200001593A
Other languages
English (en)
Inventor
John M Yani
Daniel A Gamache
Lori K Weimer
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Publication of ZA200001593B publication Critical patent/ZA200001593B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200001593A 1998-07-14 2000-03-29 Use of 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz [B,E] oxepin-2-acetic acid for the manufacture of a medicament for treating non-allergic ophthalmic inflammatory disorders and for the prevention of ocular neovascularization. ZA200001593B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9276298P 1998-07-14 1998-07-14

Publications (1)

Publication Number Publication Date
ZA200001593B true ZA200001593B (en) 2000-10-25

Family

ID=22235027

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200001593A ZA200001593B (en) 1998-07-14 2000-03-29 Use of 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz [B,E] oxepin-2-acetic acid for the manufacture of a medicament for treating non-allergic ophthalmic inflammatory disorders and for the prevention of ocular neovascularization.

Country Status (18)

Country Link
EP (1) EP1037627B1 (zh)
JP (1) JP2002520355A (zh)
KR (1) KR100598723B1 (zh)
CN (1) CN1114401C (zh)
AR (1) AR019916A1 (zh)
AT (1) ATE203668T1 (zh)
AU (1) AU742237B2 (zh)
BR (1) BR9906772A (zh)
CA (1) CA2306393C (zh)
DE (1) DE69900207T2 (zh)
DK (1) DK1037627T3 (zh)
ES (1) ES2159209T3 (zh)
GR (1) GR3036422T3 (zh)
HK (1) HK1030362A1 (zh)
PT (1) PT1037627E (zh)
TW (1) TW561046B (zh)
WO (1) WO2000003705A1 (zh)
ZA (1) ZA200001593B (zh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU770975B2 (en) 1999-06-18 2004-03-11 Alcon Laboratories, Inc. Topical ophthalmic mast cell stabilizers for treating allergic eye diseases
WO2002034246A2 (en) * 2000-10-23 2002-05-02 Alcon, Inc. Use of hydroperoxyeicosatetraenoic acid derivatives following refractive surgery
US7112588B2 (en) 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
BR0209883A (pt) 2001-05-21 2004-06-08 Alcon Inc Uso de inibidores da proteasoma para o tratamento de distúrbios do olho seco
US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
BR0209965A (pt) * 2001-05-21 2004-04-06 Alcon Inc Uso de inibidores de nf-kappab para tratar distúrbios do olho seco
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
US7977376B2 (en) 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
US6825232B2 (en) 2002-06-14 2004-11-30 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
WO2004010894A2 (en) 2002-07-30 2004-02-05 Omeros Corporation Ophthalmologic irrigation solutions and method
MXPA05003063A (es) 2002-09-20 2005-05-27 Alcon Inc Uso de inhibidores de la sintesis de citosina para el tratamiento de trastornos de ojos secos.
WO2004093878A1 (en) * 2003-04-16 2004-11-04 Alcon, Inc. Use of fused pyridazine derivatives for treating dry eye disorders
US20050232972A1 (en) 2004-04-15 2005-10-20 Steven Odrich Drug delivery via punctal plug
US7923471B2 (en) 2004-05-14 2011-04-12 Alcon, Inc. Method of treating dry eye disorders and uveitis
WO2006014434A2 (en) 2004-07-02 2006-02-09 Eliot Lazar Treatment medium delivery device and methods for delivery
US7223737B1 (en) 2004-08-13 2007-05-29 Alcon, Inc. Method of treating dry eye disorders using glycosides
DK1881823T3 (en) * 2005-05-17 2015-03-02 Sarcode Bioscience Inc COMPOSITION AND PROCEDURES FOR TREATMENT OF EYE DISORDERS
US7745461B1 (en) 2006-02-27 2010-06-29 Alcon Research, Ltd. Method of treating dry eye disorders
KR20140083056A (ko) 2006-03-17 2014-07-03 존슨 앤드 존슨 비젼 케어, 인코포레이티드 산화에 불안정한 성분을 포함하는 안정화된 안과용 조성물
CN103393496B (zh) 2006-03-31 2016-08-17 玛提治疗有限公司 用于药物治疗的鼻泪引流系统植入物
WO2009035571A2 (en) 2007-09-07 2009-03-19 Qlt Plug Delivery, Inc Lacrimal implant detection
US8207226B1 (en) 2008-06-03 2012-06-26 Alcon Research, Ltd. Use of FAAH antagonists for treating dry eye and ocular pain
JP2013510095A (ja) 2009-11-06 2013-03-21 アルコン リサーチ, リミテッド ドライアイの軽減のための栄養サプリメント
AU2013201465B2 (en) 2012-10-24 2016-03-03 Rayner Surgical (Ireland) Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI705812B (zh) 2014-12-01 2020-10-01 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
CN109311976A (zh) 2016-06-20 2019-02-05 诺华股份有限公司 使用TNFα拮抗剂治疗干眼症的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6310784A (ja) * 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
JPH02138215A (ja) * 1988-08-05 1990-05-28 Dai Ichi Seiyaku Co Ltd 抗アレルギー・抗炎症剤
IE920499A1 (en) * 1991-02-21 1992-08-26 Merck Frosst Canada Inc Quinoline-containing ketoacids as leukotriene antagonists
ZA924953B (en) * 1991-07-25 1993-04-28 Univ Louisville Res Found Method of treating ocular inflammation
JP3453152B2 (ja) * 1992-04-06 2003-10-06 格 冨山 抗炎症点眼剤
FR2701948B1 (fr) * 1993-02-22 1996-07-26 Exsymol Sa Produit de couplage de l'histamine ou l'histamine méthyl-substituée et d'un acide aminé, procédé de préparation et applications thérapeutiques, cosmétologiques et agroalimentaires.
ATE241359T1 (de) * 1993-03-26 2003-06-15 Beth Israel Hospital Topische und systemische anwendung von buspiron und seinen derivaten zur behandlung von pathologischen zuständen, die mit immunantworten verbunden sind
FR2711990B1 (fr) * 1993-11-05 1995-12-08 Exsymol Sa Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.
JP2852607B2 (ja) * 1994-06-10 1999-02-03 雪印乳業株式会社 ドライアイ治療剤
US5641805A (en) * 1995-06-06 1997-06-24 Alcon Laboratories, Inc. Topical ophthalmic formulations for treating allergic eye diseases
JPH1067684A (ja) * 1996-06-17 1998-03-10 Mitsubishi Chem Corp 涙液分泌促進剤
WO1998022130A1 (en) * 1996-11-19 1998-05-28 The Schepens Eye Research Institute, Inc. Local use of il-1ra in corneal transplant rejection or disorders of the eye

Also Published As

Publication number Publication date
EP1037627B1 (en) 2001-08-01
PT1037627E (pt) 2001-11-30
CA2306393A1 (en) 2000-01-27
DE69900207D1 (de) 2001-09-06
KR100598723B1 (ko) 2006-07-11
AR019916A1 (es) 2002-03-27
BR9906772A (pt) 2000-09-26
KR20010024508A (ko) 2001-03-26
AU4563499A (en) 2000-02-07
EP1037627A1 (en) 2000-09-27
CA2306393C (en) 2008-12-23
JP2002520355A (ja) 2002-07-09
CN1114401C (zh) 2003-07-16
ATE203668T1 (de) 2001-08-15
CN1275078A (zh) 2000-11-29
ES2159209T3 (es) 2001-09-16
HK1030362A1 (en) 2001-05-04
AU742237B2 (en) 2001-12-20
GR3036422T3 (en) 2001-11-30
DK1037627T3 (da) 2001-10-01
TW561046B (en) 2003-11-11
WO2000003705A1 (en) 2000-01-27
DE69900207T2 (de) 2001-11-22

Similar Documents

Publication Publication Date Title
ZA200001593B (en) Use of 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz [B,E] oxepin-2-acetic acid for the manufacture of a medicament for treating non-allergic ophthalmic inflammatory disorders and for the prevention of ocular neovascularization.
HK1085647A1 (en) Benzo [d]azepine derivatives for the treatment of neurological disorders
EP1100508B8 (en) Pharmaceutical combination comprising a tricyclic compound and at least one of zolpidem, zopiclone and brotizolam for treating or preventing sleep disorders
MY116651A (en) Topical ophthalmic formulations for treating allergic eye diseases
HUP0000576A3 (en) Use of green porphyrins for the manufacture of a medicament for the treatment of secondary cataracts
SI1299383T1 (en) Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders
HUP0002742A3 (en) New therapeutic combinations of mirtazapine and antipsychotic agents, for the treatment or prophylaxis of psychotic disorders
BG106509A (en) Preparative form
NO20013645L (no) Anvendelse av pyridazino[4,5-b]indol-1-acetamid-derivater for fremstilling av medisiner for behandling av sykdommer relatert tildysfunksjon av de perifere benzodiazepinreseptorer
AU2001256855A1 (en) Preparation for the prevention and treatment of ocular disorders
EP1440691A3 (en) Treatment of neurotic disorders
EP1126850A4 (en) TREATMENT OF CONDITIONS OF THE RETINA
GB9926968D0 (en) Treatment of neurological disorders
AU1546101A (en) Pharmaceutical compositions comprising acetylcholinesterase antisense deoxynucleotides for the treatment of muscular and neuromuscular disorders
AU5912900A (en) Quinuclidine derivatives for treatment of neurological disorders
WO2002043715A3 (de) Verwendung von 1-phenyl-3-dimethylamino-propanverbindungen zur therapie der harninkontinenz
AU6386700A (en) Cis-2,6-disubstituted piperidines for the treatment of psychostimulant abuse and withdrawal, eating disorders, and central nervous system diseases and pathologies
HK1057332A1 (en) Use of 3-benzoylphenylacetic acid derivatives for the treatment of retinal disorders
HK1047695A1 (en) Use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina
CA2260863A1 (en) Treatment of psychotic disorders
MXPA01003761A (es) Agente para tratar oftalmopatia.
WO2002043714A3 (de) Verwendung von substituierten 6-dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur therapie der harninkontinenz
PL365576A1 (en) S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders
IL149669A0 (en) NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS
EP1142585A4 (en) DRUGS AGAINST CORNEAL DISORDERS