YU89692A - Postupak za proizvodnju bakterijskog kapsularnog polisaharida koji sadrži lipid u polisaharid bez lipida - Google Patents

Postupak za proizvodnju bakterijskog kapsularnog polisaharida koji sadrži lipid u polisaharid bez lipida

Info

Publication number
YU89692A
YU89692A YU89692A YU89692A YU89692A YU 89692 A YU89692 A YU 89692A YU 89692 A YU89692 A YU 89692A YU 89692 A YU89692 A YU 89692A YU 89692 A YU89692 A YU 89692A
Authority
YU
Yugoslavia
Prior art keywords
lipid
polysaccharide
free
procedure
manufacture
Prior art date
Application number
YU89692A
Other languages
English (en)
Inventor
A.L. Lee
W.E. Manger
M.S. Rienstra
R.D. Sitrin
Original Assignee
Merck And Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/909,346 external-priority patent/US5314811A/en
Application filed by Merck And Co. Inc. filed Critical Merck And Co. Inc.
Publication of YU89692A publication Critical patent/YU89692A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

POSTUPAK ZA PROIZVODNJU BAKTERIJSKOG KAPSULARNOG POLISAHARIDA KOJI SADRŽI LIPID U POLISAHARID BEZ LIPIDA, postupak za prevodjenje bakterijskog kapsuliranog polisaharida koji sadrži lipid, takav kao što je lipo-poliribozil ribitol fosfat, lipo-PRP, u polisaharid bez lipida, bez endotoksina, takav kao što je poliribozil ribitol fosfat, PRP, prevodjenjem u rastvor praha koji sadrži polisaharid koji potiče iz podloge gajenja bakterije, takve kao što je Haemophilus influenzae tip b, ocepljivanjem kovalentno vezanih masnih kiselina iz polisaharida, i odstranjivanjem lipida, i endotoksina.
YU89692A 1991-08-16 1992-10-07 Postupak za proizvodnju bakterijskog kapsularnog polisaharida koji sadrži lipid u polisaharid bez lipida YU89692A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74652391A 1991-08-16 1991-08-16
US07/909,346 US5314811A (en) 1992-07-13 1992-07-13 Process for converting lipid-containing bacterial capsular polysaccharide into lipid-free polysaccharide

Publications (1)

Publication Number Publication Date
YU89692A true YU89692A (sh) 1995-10-24

Family

ID=27114616

Family Applications (1)

Application Number Title Priority Date Filing Date
YU89692A YU89692A (sh) 1991-08-16 1992-10-07 Postupak za proizvodnju bakterijskog kapsularnog polisaharida koji sadrži lipid u polisaharid bez lipida

Country Status (18)

Country Link
EP (1) EP0528635B1 (sh)
JP (1) JPH05209002A (sh)
KR (1) KR930004473A (sh)
CN (1) CN1071699A (sh)
AT (1) ATE176929T1 (sh)
AU (1) AU2105492A (sh)
BG (1) BG98470A (sh)
CA (1) CA2075681C (sh)
CZ (1) CZ28694A3 (sh)
DE (1) DE69228454T2 (sh)
FI (1) FI940700A0 (sh)
HU (1) HU9400426D0 (sh)
IL (1) IL102763A0 (sh)
MX (1) MX9204721A (sh)
NZ (1) NZ243892A (sh)
SK (1) SK18594A3 (sh)
WO (1) WO1993004183A1 (sh)
YU (1) YU89692A (sh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410025B1 (en) 1996-02-14 2002-06-25 Merck & Co., Inc. Polysaccharide precipitation process
DE69731380T2 (de) * 1996-02-14 2006-02-23 Merck & Co., Inc. Verfahren zur präzipitation von polysacchariden
SE0003958D0 (sv) 2000-10-31 2000-10-31 Biogaia Fermentation Ab Method for growth of microorganisms
ES2388848T3 (es) 2001-01-23 2012-10-19 Sanofi Pasteur Inc. Vacuna meningocócica polivalente preparada con un conjugado de polisacárido y proteína
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
KR100826963B1 (ko) * 2001-11-13 2008-05-02 주식회사 포스코 고로 노심온도 관리 방법
GB0408978D0 (en) * 2004-04-22 2004-05-26 Chiron Srl Meningococcal fermentation for preparing conjugate vaccines
JP2010520320A (ja) * 2007-02-28 2010-06-10 リポクセン テクノロジーズ リミテッド ポリシアル酸におけるエンドトキシンの低減
FR2918671B1 (fr) 2007-07-10 2010-10-15 Sanofi Pasteur Milieu de culture d'haemophilus influenzae type b.
CN101724085B (zh) * 2008-10-22 2011-09-21 上海生物制品研究所 一种荚膜多糖纯化方法
CN103059149B (zh) * 2011-10-19 2016-08-31 天士力制药集团股份有限公司 一种prp多糖提取方法
CN102660602B (zh) * 2012-04-17 2015-03-25 江苏康泰生物医学技术有限公司 快速纯化细菌荚膜多糖的方法
CN102731670B (zh) * 2012-06-29 2014-09-03 成都欧林生物科技股份有限公司 Hib荚膜多糖纯化工艺
BR102019021510A2 (pt) * 2019-10-14 2022-01-25 Instituto Butantan Processo de produção, recuperação e purificação de polissacarídeo capsular poliribosil-ribitol-fosfato (prp) e uso do mesmo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2316964A1 (fr) * 1975-07-11 1977-02-04 Pasteur Institut Medicament contenant, a titre de principe actif, un produit a base de polysaccharides, notamment obtenu a partir de lipopolysaccharides bacteriens
NZ188211A (en) * 1977-10-28 1984-09-28 American Cyanamid Co Isolation of polyribosyl ribitol phosphate(prp)from haemophilus influenzae type b;vaccine comprising prp and bordetellapertussis antigens

Also Published As

Publication number Publication date
CA2075681C (en) 2003-03-25
MX9204721A (es) 1993-07-01
CN1071699A (zh) 1993-05-05
CA2075681A1 (en) 1993-02-17
CZ28694A3 (en) 1994-05-18
FI940700A (fi) 1994-02-15
NZ243892A (en) 1994-06-27
HU9400426D0 (en) 1994-05-30
JPH05209002A (ja) 1993-08-20
IL102763A0 (en) 1993-01-31
BG98470A (en) 1994-12-02
DE69228454T2 (de) 1999-07-15
FI940700A0 (fi) 1994-02-15
WO1993004183A1 (en) 1993-03-04
EP0528635A1 (en) 1993-02-24
ATE176929T1 (de) 1999-03-15
KR930004473A (ko) 1993-03-22
SK18594A3 (en) 1994-08-10
DE69228454D1 (de) 1999-04-01
EP0528635B1 (en) 1999-02-24
AU2105492A (en) 1993-02-18

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