YU66300A - Antitelo, specifično prema fap alfa, sa poboljšanom produktivnošću - Google Patents
Antitelo, specifično prema fap alfa, sa poboljšanom produktivnošćuInfo
- Publication number
- YU66300A YU66300A YU66300A YU66300A YU66300A YU 66300 A YU66300 A YU 66300A YU 66300 A YU66300 A YU 66300A YU 66300 A YU66300 A YU 66300A YU 66300 A YU66300 A YU 66300A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- specific antibody
- fap alpha
- improved producibility
- producibility
- improved
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102100023832 Prolyl endopeptidase FAP Human genes 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000002950 fibroblast Anatomy 0.000 abstract 1
- 108010072257 fibroblast activation protein alpha Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98107925A EP0953639A1 (en) | 1998-04-30 | 1998-04-30 | FAPalpha-specific antibody with improved producibility |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU66300A true YU66300A (sh) | 2004-03-12 |
Family
ID=8231860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU66300A YU66300A (sh) | 1998-04-30 | 1999-04-22 | Antitelo, specifično prema fap alfa, sa poboljšanom produktivnošću |
Country Status (27)
| Country | Link |
|---|---|
| EP (2) | EP0953639A1 (enExample) |
| JP (1) | JP4421779B2 (enExample) |
| KR (1) | KR100580936B1 (enExample) |
| CN (1) | CN1303430A (enExample) |
| AR (1) | AR016243A1 (enExample) |
| AT (1) | ATE356873T1 (enExample) |
| AU (1) | AU760305B2 (enExample) |
| BG (1) | BG65034B1 (enExample) |
| BR (1) | BR9910577A (enExample) |
| CA (1) | CA2327586C (enExample) |
| CO (1) | CO5050255A1 (enExample) |
| DE (1) | DE69935516T2 (enExample) |
| EA (1) | EA005401B1 (enExample) |
| EE (1) | EE200000642A (enExample) |
| ES (1) | ES2283114T3 (enExample) |
| HU (1) | HUP0101501A3 (enExample) |
| ID (1) | ID26555A (enExample) |
| IL (1) | IL138701A0 (enExample) |
| NO (1) | NO20005412L (enExample) |
| NZ (1) | NZ508456A (enExample) |
| PL (1) | PL358087A1 (enExample) |
| SK (1) | SK16192000A3 (enExample) |
| TR (1) | TR200003181T2 (enExample) |
| UA (1) | UA73276C2 (enExample) |
| WO (1) | WO1999057151A2 (enExample) |
| YU (1) | YU66300A (enExample) |
| ZA (1) | ZA200005506B (enExample) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7883704B2 (en) | 1999-03-25 | 2011-02-08 | Abbott Gmbh & Co. Kg | Methods for inhibiting the activity of the P40 subunit of human IL-12 |
| US6914128B1 (en) | 1999-03-25 | 2005-07-05 | Abbott Gmbh & Co. Kg | Human antibodies that bind human IL-12 and methods for producing |
| JP2003530092A (ja) * | 2000-03-17 | 2003-10-14 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | ヒトＦＡＰ−α−特異抗体 |
| PE20021080A1 (es) * | 2001-04-12 | 2003-02-12 | Boehringer Ingelheim Int | Un anticuerpo especifico fapo bibh1 en el tratamiento del cancer |
| JP2005530856A (ja) * | 2002-06-21 | 2005-10-13 | ジョンズ ホプキンス ユニバーシティー スクール オブ メディシン | 膜関連腫瘍内皮マーカー |
| US8187593B2 (en) | 2002-08-14 | 2012-05-29 | Macrogenics, Inc. | FcγRIIB specific antibodies and methods of use thereof |
| US8946387B2 (en) | 2002-08-14 | 2015-02-03 | Macrogenics, Inc. | FcγRIIB specific antibodies and methods of use thereof |
| US8530627B2 (en) | 2002-08-14 | 2013-09-10 | Macrogenics, Inc. | FcγRIIB specific antibodies and methods of use thereof |
| US8968730B2 (en) | 2002-08-14 | 2015-03-03 | Macrogenics Inc. | FcγRIIB specific antibodies and methods of use thereof |
| CA2495251C (en) | 2002-08-14 | 2018-03-06 | Macrogenics, Inc. | Fc.gamma.riib-specific antibodies and methods of use thereof |
| US8044180B2 (en) | 2002-08-14 | 2011-10-25 | Macrogenics, Inc. | FcγRIIB specific antibodies and methods of use thereof |
| US8193318B2 (en) | 2002-08-14 | 2012-06-05 | Macrogenics, Inc. | FcγRIIB specific antibodies and methods of use thereof |
| US7384744B2 (en) | 2002-11-29 | 2008-06-10 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Expression vector, methods for the production of heterologous gene products and for the selection of recombinant cells producing high levels of such products |
| US7960512B2 (en) | 2003-01-09 | 2011-06-14 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
| WO2004063351A2 (en) | 2003-01-09 | 2004-07-29 | Macrogenics, Inc. | IDENTIFICATION AND ENGINEERING OF ANTIBODIES WITH VARIANT Fc REGIONS AND METHODS OF USING SAME |
| MXPA05008523A (es) * | 2003-02-14 | 2005-10-20 | Biogen Idec Inc | Un casete de expresion y vector para la expresion transitoria o estable de moleculas exogenas. |
| JP2007536932A (ja) | 2004-05-10 | 2007-12-20 | マクロジェニクス，インコーポレーテッド | ヒト化ＦｃγＲＩＩＢ特異的抗体とその利用法 |
| US7632497B2 (en) | 2004-11-10 | 2009-12-15 | Macrogenics, Inc. | Engineering Fc Antibody regions to confer effector function |
| EP2573114B1 (en) | 2005-08-10 | 2016-03-30 | MacroGenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
| KR101866623B1 (ko) * | 2005-11-28 | 2018-07-04 | 젠맵 에이/에스 | 재조합 １가 항체 및 그의 제조 방법 |
| EP1806365A1 (en) * | 2006-01-05 | 2007-07-11 | Boehringer Ingelheim International GmbH | Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them |
| US7786270B2 (en) | 2006-05-26 | 2010-08-31 | Macrogenics, Inc. | Humanized FcγRIIB-specific antibodies and methods of use thereof |
| SI2029173T1 (sl) | 2006-06-26 | 2016-12-30 | Macrogenics, Inc. | Protitelesa, specifična za Fc RIIB, in postopki za njihovo uporabo |
| EP2032159B1 (en) | 2006-06-26 | 2015-01-07 | MacroGenics, Inc. | Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof |
| WO2008140603A2 (en) | 2006-12-08 | 2008-11-20 | Macrogenics, Inc. | METHODS FOR THE TREATMENT OF DISEASE USING IMMUNOGLOBULINS HAVING FC REGIONS WITH ALTERED AFFINITIES FOR FCγR ACTIVATING AND FCγR INHIBITING |
| MX2009007570A (es) | 2007-01-16 | 2009-07-22 | Abbott Lab | Metodos para tratar la psoriasis. |
| NZ598881A (en) | 2007-03-29 | 2013-11-29 | Abbvie Inc | Crystalline anti-human il-12 antibodies |
| WO2009151717A2 (en) | 2008-04-02 | 2009-12-17 | Macrogenics, Inc. | Bcr-complex-specific antibodies and methods of using same |
| DK3216802T3 (da) * | 2007-08-20 | 2021-01-04 | Glaxo Group Ltd | Produktionsfremgangsmåde |
| EP2223115B1 (en) | 2007-12-10 | 2011-09-14 | Roche Diagnostics GmbH | Seprase as a marker for cancer |
| EP2071337A1 (en) * | 2007-12-10 | 2009-06-17 | F.Hoffmann-La Roche Ag | Seprase as a marker for cancer |
| JP5591711B2 (ja) * | 2007-12-10 | 2014-09-17 | エフ．ホフマン−ラ ロシュ アーゲー | 結腸直腸癌のためのマーカーパネル |
| JP2011515404A (ja) | 2008-03-18 | 2011-05-19 | アボット・ラボラトリーズ | 乾癬を治療するための方法 |
| BRPI0906309A2 (pt) | 2008-04-02 | 2020-05-26 | Macrogenics, Inc | Imunoglobulina, anticorpo, uso do anticorpo e composição farmacêutica |
| SG179135A1 (en) | 2009-09-14 | 2012-05-30 | Abbott Lab | Methods for treating psoriasis |
| CA2776385C (en) | 2009-10-07 | 2019-04-09 | Macrogenics, Inc. | Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use |
| PH12018501083A1 (en) | 2010-03-04 | 2019-02-18 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| HUE036077T2 (hu) * | 2010-08-13 | 2018-06-28 | Roche Glycart Ag | Anti-FAP ellenanyagok és alkalmazásukra szolgáló eljárások |
| PH12020550156A1 (en) | 2010-09-09 | 2024-01-15 | Pfizer | 4-1bb binding molecules |
| EP2673294B1 (en) | 2011-02-10 | 2016-04-27 | Roche Glycart AG | Mutant interleukin-2 polypeptides |
| DK2859017T3 (da) | 2012-06-08 | 2019-05-13 | Sutro Biopharma Inc | Antistoffer omfattrende stedsspecifikke ikke-naturlige aminosyrerester, fremgangsmåder til fremstilling heraf og fremgangsmåder til anvendelse heraf |
| ES2611788T3 (es) | 2012-06-26 | 2017-05-10 | Sutro Biopharma, Inc. | Proteínas de Fc modificadas que comprenden residuos de aminoácidos no naturales específicos del sitio, conjugados de las mismas, métodos para su preparación y métodos para su uso |
| US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| UA118028C2 (uk) | 2013-04-03 | 2018-11-12 | Рош Глікарт Аг | Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування |
| CN103267852B (zh) * | 2013-05-15 | 2015-03-25 | 中国医学科学院北京协和医院 | 成纤维激活蛋白α在制备胰腺癌预后试剂盒中的用途 |
| ES2865473T3 (es) | 2013-07-10 | 2021-10-15 | Sutro Biopharma Inc | Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso |
| GB201402006D0 (en) | 2014-02-06 | 2014-03-26 | Oncomatryx Biopharma S L | Antibody-drug conjugates and immunotoxins |
| DK3122775T3 (da) * | 2014-03-26 | 2020-02-03 | Univ Wuerzburg J Maximilians | Monoklonale antistoffer til vækst- og differentieringsfaktor 15 (gdf-15), og anvendelser deraf til behandling af cancer kakeksi og cancer |
| CN105646710B (zh) * | 2014-11-17 | 2020-08-25 | 四川科伦博泰生物医药股份有限公司 | 一种全人源化抗vegfr-2单克隆抗体及其制备方法 |
| AU2016329120B2 (en) | 2015-10-02 | 2023-04-13 | F. Hoffmann-La Roche Ag | Bispecific antibodies specific for a costimulatory TNF receptor |
| CN109069664B (zh) * | 2016-01-27 | 2022-05-13 | 苏特罗生物制药公司 | 抗cd74抗体偶联物，包含抗cd74抗体偶联物的组合物以及抗cd74抗体偶联物的使用方法 |
| EP3442574A4 (en) | 2016-04-15 | 2019-12-11 | MacroGenics, Inc. | Novel B7-H3 binding MOLECULES, ANTIBODY-ACTIVE CONJUGATES AND METHOD OF USE THEREOF |
| CA3029426A1 (en) | 2016-06-30 | 2018-01-04 | Oncorus, Inc. | Pseudotyped oncolytic viral delivery of therapeutic polypeptides |
| JP2018035137A (ja) | 2016-07-13 | 2018-03-08 | マブイミューン ダイアグノスティックス エイジーＭａｂｉｍｍｕｎｅ Ｄｉａｇｎｏｓｔｉｃｓ Ａｇ | 新規な抗線維芽細胞活性化タンパク質（ｆａｐ）結合薬剤およびその使用 |
| CN110291401B (zh) | 2016-12-14 | 2023-04-11 | 普渡研究基金会 | 成纤维细胞活化蛋白(fap)-靶向成像和治疗 |
| JP2021508477A (ja) | 2017-12-29 | 2021-03-11 | オンコラス， インコーポレイテッド | 治療用ポリペプチドの腫瘍溶解性ウイルス送達 |
| CN110526991A (zh) * | 2018-05-25 | 2019-12-03 | 深圳宾德生物技术有限公司 | 靶向fap的嵌合抗原受体、嵌合抗原受体t细胞及其制备方法和应用 |
| CN110526979A (zh) * | 2018-05-25 | 2019-12-03 | 深圳宾德生物技术有限公司 | 靶向fap的单链抗体、嵌合抗原受体t细胞及其制备方法和应用 |
| CN109053893B (zh) * | 2018-08-15 | 2021-03-30 | 智享生物(苏州)有限公司 | 一种抗d-二聚体单克隆抗体及其制备方法 |
| CN112972675A (zh) * | 2018-09-07 | 2021-06-18 | 上海君实生物医药科技股份有限公司 | 抗pd-1抗体在治疗肿瘤中的用途 |
| CN114853908B (zh) * | 2019-05-16 | 2024-06-07 | 浙江道尔生物科技有限公司 | 一种治疗代谢疾病的融合蛋白 |
| EP3997104A1 (en) | 2019-07-08 | 2022-05-18 | 3B Pharmaceuticals GmbH | Compounds comprising a fibroblast activation protein ligand and use thereof |
| EP3763726A1 (en) | 2019-07-08 | 2021-01-13 | 3B Pharmaceuticals GmbH | Compounds comprising a fibroblast activation protein ligand and use thereof |
| JP7608425B2 (ja) | 2019-07-08 | 2025-01-06 | ３ベー ファーマシューティカルズ ゲーエムベーハー | 線維芽細胞活性化タンパク質リガンドを含む化合物およびその使用 |
| CN117683133A (zh) * | 2019-09-03 | 2024-03-12 | 百奥泰生物制药股份有限公司 | 一种抗tigit免疫抑制剂及应用 |
| CN113512116B (zh) * | 2020-04-10 | 2022-09-20 | 苏州普乐康医药科技有限公司 | 一种抗igf-1r抗体及其应用 |
| KR102363980B1 (ko) * | 2020-04-13 | 2022-02-15 | 전남대학교산학협력단 | 전이성 뇌종양의 진단 또는 예후 분석용 바이오마커 및 이를 이용한 진단방법 |
| WO2021219092A1 (en) * | 2020-04-30 | 2021-11-04 | I-Mab Biopharma Co., Ltd. | Pharmaceutical compositionscontaining anti-cd47 antibodies |
| EP4153316A1 (en) | 2020-05-19 | 2023-03-29 | Boehringer Ingelheim International GmbH | Binding molecules for the treatment of cancer |
| WO2022007283A1 (zh) * | 2020-07-08 | 2022-01-13 | 深圳霁因生物医药转化研究院 | 用于诊断fap表达异常相关疾病的试剂盒、方法及计算机可读存储介质 |
| KR102784691B1 (ko) * | 2020-08-11 | 2025-03-25 | 주식회사 카나프테라퓨틱스 | Il-12 및 항-cd20 항체를 포함하는 융합단백질 및 이의 용도 |
| EP4050018A1 (en) | 2021-01-07 | 2022-08-31 | 3B Pharmaceuticals GmbH | Compounds comprising a fibroblast activation protein ligand and use thereof |
| JP2024503637A (ja) | 2021-01-07 | 2024-01-26 | ３ベー ファーマシューティカルズ ゲーエムベーハー | 線維芽細胞活性化タンパク質リガンドを含む化合物およびその使用 |
| WO2023031644A1 (en) | 2021-08-31 | 2023-03-09 | Full-Life Technologies Limited | Anti-fibroblast activation protein (fap) single domain antibodies and uses thereof |
| EP4457346A1 (en) * | 2021-12-30 | 2024-11-06 | Concept to Medicine Biotech Co., Ltd. | Human antibodies against fap-alpha |
| WO2024027771A1 (zh) | 2022-08-03 | 2024-02-08 | 南京维立志博生物科技有限公司 | 靶向FAP和TGFβ的抗体融合蛋白及其用途 |
| WO2024074727A1 (en) | 2022-10-07 | 2024-04-11 | Genethon | Immunotherapy of skeletal myopathies using anti-fap car-t cells |
| CN116589566A (zh) * | 2022-11-18 | 2023-08-15 | 昆明医科大学第一附属医院 | 一种HIV-1中和抗体的改造重组单克隆IgM抗体及其应用 |
| WO2025152756A1 (zh) * | 2024-01-15 | 2025-07-24 | 迈威(上海)生物科技股份有限公司 | 重组抗fap抗体及其应用 |
| CN118496382B (zh) * | 2024-05-22 | 2025-01-07 | 山东第一医科大学附属省立医院(山东省立医院) | 一种靶向fap的嵌合抗原受体、car-t细胞及其在肝纤维化中的应用 |
| CN119265201A (zh) * | 2024-08-23 | 2025-01-07 | 中国人民解放军海军军医大学第一附属医院 | 编码基因、蛋白、表达il-15的nkg2dl-fap双靶点car-nk细胞及其构建方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5059523A (en) * | 1988-05-02 | 1991-10-22 | Sloan-Kettering Institute For Cancer Research | Cell-surface glycoproteins of human sarcomas |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| WO1993005804A1 (en) * | 1991-09-18 | 1993-04-01 | Sloan-Kettering Institute For Cancer Research | Activated stromal fibroblast-specific antibody, f19 and methods of using the same |
| ZA936260B (en) * | 1992-09-09 | 1994-03-18 | Smithkline Beecham Corp | Novel antibodies for conferring passive immunity against infection by a pathogen in man |
| CA2229043C (en) * | 1995-08-18 | 2016-06-07 | Morphosys Gesellschaft Fur Proteinoptimierung Mbh | Protein/(poly)peptide libraries |
| CA2248653C (en) * | 1996-05-01 | 2003-08-12 | Genitope Corporation | Vaccines for treatment of lymphoma and leukemia |
-
1998
- 1998-04-30 EP EP98107925A patent/EP0953639A1/en not_active Withdrawn
-
1999
- 1999-04-22 WO PCT/EP1999/002711 patent/WO1999057151A2/en not_active Ceased
- 1999-04-22 YU YU66300A patent/YU66300A/sh unknown
- 1999-04-22 ID IDW20002198A patent/ID26555A/id unknown
- 1999-04-22 CN CN99806582A patent/CN1303430A/zh active Pending
- 1999-04-22 ES ES99923439T patent/ES2283114T3/es not_active Expired - Lifetime
- 1999-04-22 NZ NZ508456A patent/NZ508456A/xx unknown
- 1999-04-22 AT AT99923439T patent/ATE356873T1/de active
- 1999-04-22 DE DE69935516T patent/DE69935516T2/de not_active Expired - Lifetime
- 1999-04-22 EE EEP200000642A patent/EE200000642A/xx unknown
- 1999-04-22 PL PL99358087A patent/PL358087A1/xx not_active IP Right Cessation
- 1999-04-22 CA CA2327586A patent/CA2327586C/en not_active Expired - Lifetime
- 1999-04-22 JP JP2000547119A patent/JP4421779B2/ja not_active Expired - Lifetime
- 1999-04-22 AU AU40322/99A patent/AU760305B2/en not_active Ceased
- 1999-04-22 IL IL13870199A patent/IL138701A0/xx unknown
- 1999-04-22 HU HU0101501A patent/HUP0101501A3/hu unknown
- 1999-04-22 SK SK1619-2000A patent/SK16192000A3/sk unknown
- 1999-04-22 TR TR2000/03181T patent/TR200003181T2/xx unknown
- 1999-04-22 UA UA2000116786A patent/UA73276C2/uk unknown
- 1999-04-22 BR BR9910577-2A patent/BR9910577A/pt not_active IP Right Cessation
- 1999-04-22 EA EA200001023A patent/EA005401B1/ru not_active IP Right Cessation
- 1999-04-22 KR KR1020007011585A patent/KR100580936B1/ko not_active Expired - Fee Related
- 1999-04-22 EP EP99923439A patent/EP1098979B1/en not_active Expired - Lifetime
- 1999-04-29 CO CO99025997A patent/CO5050255A1/es unknown
- 1999-04-30 AR ARP990102015A patent/AR016243A1/es unknown
-
2000
- 2000-10-05 BG BG104828A patent/BG65034B1/bg unknown
- 2000-10-09 ZA ZA200005506A patent/ZA200005506B/en unknown
- 2000-10-27 NO NO20005412A patent/NO20005412L/no not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| YU66300A (sh) | Antitelo, specifično prema fap alfa, sa poboljšanom produktivnošću | |
| EA200000216A1 (ru) | Белки, связывающие интерлейкин-18, их получение и применение | |
| PT87138A (pt) | Process for the preparation of adn recombinant molecules codin g polypeptide adn segments and of antibody compositions relate d with human tissue factor | |
| FI972390A0 (fi) | Sytokiini nimeltä Lerk-7 | |
| DE3785186D1 (de) | Bindungsmolekuele mit einzelpolypeptidkette. | |
| WO2003060090A3 (en) | Novel cytokine zcytor17 ligand | |
| DE69033735D1 (de) | Varianten von adhäsionsmoleküle für blutplättchen | |
| DE69841102D1 (de) | Monoklonaler antikörper gegen ein prion protein und dessen verwendung zum nachweis von prionen | |
| DE69132902D1 (de) | Methoden zur identifizierung heterofunktionaler fusionsproteine | |
| ATE135371T1 (de) | Mit akuter pankreatitis assoziiertes protein, mittel zur diagnose von akuter pankreatitis | |
| ATE387458T1 (de) | Fas-antigenbindender ligand | |
| ATE450603T1 (de) | Polypeptide mit verzweigungsenzym-aktivität und für diese kodierende nukleinsäuren | |
| WO2003065003A3 (en) | Nuclear matrix protein alterations associated with colon cancer and colon metastasis to the liver, and uses thereof | |
| PT1200561E (pt) | Clone celular recombinante estavel, sua producao e utilizacao | |
| ES2421558T3 (es) | Anticuerpos específicos de cáncer y proteínas de superficie celular | |
| HUP0101987A2 (hu) | Antibiotikus hatású proteinek és peptidek indukciója LAIT/sCD14-proteinnel | |
| WO2000018803A3 (en) | Antibodies to mammalian langerhans cell antigen and their uses | |
| MY143274A (en) | Recombinant production of heparin binding proteins | |
| ATE309363T1 (de) | Hybrid-toxine von bacillus thuringiensis | |
| EP0676413A3 (en) | Interferon alpha / beta binding protein, its production and application. | |
| PT1127133E (pt) | Polipeptido que proporciona permeabilidade celular | |
| DK0487229T3 (da) | DNA, der koder for et protein, som binder til enhanceren for alfa-føtoproteingenet | |
| WO2003031590A3 (en) | Nucleic acids encoding linked chromo/fluorescent domains and methods for using the same | |
| DE69932644D1 (de) | Menschliches Protein mit in vitro antiproliferativer Aktivität. | |
| UY25549A1 (es) | Metodo para producir un anticuerpo especifico de fap-alfa con productividad mejorada. |