CA2327586C - Fap.alpha.-specific antibody with improved producibility - Google Patents
Fap.alpha.-specific antibody with improved producibility Download PDFInfo
- Publication number
- CA2327586C CA2327586C CA2327586A CA2327586A CA2327586C CA 2327586 C CA2327586 C CA 2327586C CA 2327586 A CA2327586 A CA 2327586A CA 2327586 A CA2327586 A CA 2327586A CA 2327586 C CA2327586 C CA 2327586C
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- ser
- seq
- val
- gly
- thr
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
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Applications Claiming Priority (3)
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| EP98107925A EP0953639A1 (en) | 1998-04-30 | 1998-04-30 | FAPalpha-specific antibody with improved producibility |
| EP98107925.4 | 1998-04-30 | ||
| PCT/EP1999/002711 WO1999057151A2 (en) | 1998-04-30 | 1999-04-22 | FAP α-SPECIFIC ANTIBODY WITH IMPROVED PRODUCIBILITY |
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| CA2327586A1 CA2327586A1 (en) | 1999-11-11 |
| CA2327586C true CA2327586C (en) | 2013-02-26 |
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| CA2327586A Expired - Lifetime CA2327586C (en) | 1998-04-30 | 1999-04-22 | Fap.alpha.-specific antibody with improved producibility |
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|---|---|---|---|---|
| US7883704B2 (en) | 1999-03-25 | 2011-02-08 | Abbott Gmbh & Co. Kg | Methods for inhibiting the activity of the P40 subunit of human IL-12 |
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| AU716257B2 (en) * | 1996-05-01 | 2000-02-24 | Genitope Corporation | Vaccines for treatment of lymphoma and leukemia |
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