ATE524740T1 - Seprase als krebsmarker - Google Patents
Seprase als krebsmarkerInfo
- Publication number
- ATE524740T1 ATE524740T1 AT08859952T AT08859952T ATE524740T1 AT E524740 T1 ATE524740 T1 AT E524740T1 AT 08859952 T AT08859952 T AT 08859952T AT 08859952 T AT08859952 T AT 08859952T AT E524740 T1 ATE524740 T1 AT E524740T1
- Authority
- AT
- Austria
- Prior art keywords
- cancer
- seprase
- types
- assessment
- specific
- Prior art date
Links
- 102100023832 Prolyl endopeptidase FAP Human genes 0.000 title abstract 6
- 108010072257 fibroblast activation protein alpha Proteins 0.000 title abstract 6
- 239000000439 tumor marker Substances 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 6
- 201000011510 cancer Diseases 0.000 abstract 6
- 206010009944 Colon cancer Diseases 0.000 abstract 3
- 208000020816 lung neoplasm Diseases 0.000 abstract 3
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 abstract 2
- 201000005202 lung cancer Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000002154 non-small cell lung carcinoma Diseases 0.000 abstract 2
- 206010004593 Bile duct cancer Diseases 0.000 abstract 1
- 206010005003 Bladder cancer Diseases 0.000 abstract 1
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 206010014733 Endometrial cancer Diseases 0.000 abstract 1
- 206010014759 Endometrial neoplasm Diseases 0.000 abstract 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 abstract 1
- 208000008839 Kidney Neoplasms Diseases 0.000 abstract 1
- 206010033128 Ovarian cancer Diseases 0.000 abstract 1
- 206010061535 Ovarian neoplasm Diseases 0.000 abstract 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 206010038389 Renal cancer Diseases 0.000 abstract 1
- 208000005718 Stomach Neoplasms Diseases 0.000 abstract 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 abstract 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 abstract 1
- 208000026900 bile duct neoplasm Diseases 0.000 abstract 1
- 201000010881 cervical cancer Diseases 0.000 abstract 1
- 208000006990 cholangiocarcinoma Diseases 0.000 abstract 1
- 208000029742 colonic neoplasm Diseases 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 201000004101 esophageal cancer Diseases 0.000 abstract 1
- 210000003238 esophagus Anatomy 0.000 abstract 1
- 206010017758 gastric cancer Diseases 0.000 abstract 1
- 201000010536 head and neck cancer Diseases 0.000 abstract 1
- 208000014829 head and neck neoplasm Diseases 0.000 abstract 1
- 201000010982 kidney cancer Diseases 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 208000008443 pancreatic carcinoma Diseases 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 201000011549 stomach cancer Diseases 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
- 201000005112 urinary bladder cancer Diseases 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57473—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen, i.e. CEA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96402—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
- G01N2333/96405—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
- G01N2333/96408—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
- G01N2333/96411—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07023897A EP2071337A1 (de) | 2007-12-10 | 2007-12-10 | Seprase als Krebsmarker |
| EP08015310 | 2008-08-29 | ||
| PCT/EP2008/010385 WO2009074275A1 (en) | 2007-12-10 | 2008-12-08 | Seprase as a marker for cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE524740T1 true ATE524740T1 (de) | 2011-09-15 |
Family
ID=40373548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08859952T ATE524740T1 (de) | 2007-12-10 | 2008-12-08 | Seprase als krebsmarker |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8980573B2 (de) |
| EP (1) | EP2223115B1 (de) |
| JP (1) | JP5563988B2 (de) |
| KR (1) | KR101202220B1 (de) |
| CN (1) | CN101896818B (de) |
| AT (1) | ATE524740T1 (de) |
| AU (1) | AU2008335855B2 (de) |
| BR (1) | BRPI0820793A2 (de) |
| CA (1) | CA2706115A1 (de) |
| DK (1) | DK2223115T3 (de) |
| ES (1) | ES2372442T3 (de) |
| MX (1) | MX2010004671A (de) |
| PL (1) | PL2223115T3 (de) |
| WO (1) | WO2009074275A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8213005B2 (en) | 2003-07-22 | 2012-07-03 | King Saud University | Method for discriminating between benign and malignant prostate tumors |
| ES2408964T3 (es) * | 2008-07-03 | 2013-06-24 | F. Hoffmann-La Roche Ag | ASC como marcador del cáncer de pulmón |
| EP3112871B1 (de) | 2009-12-20 | 2020-07-29 | Astute Medical, Inc. | Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz |
| PL2666872T3 (pl) * | 2010-02-05 | 2016-10-31 | Sposoby i kompozycje do diagnozowania i prognozowania uszkodzenia nerek i niewydolności nerek | |
| CA2815356A1 (en) * | 2010-10-20 | 2012-04-26 | Rush University Medical Center | Lung cancer tests |
| JP5976695B2 (ja) * | 2011-03-11 | 2016-08-24 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 慢性閉塞性肺疾患（ｃｏｐｄ）のマーカーとしてのａｓｃ |
| CN103415772A (zh) * | 2011-03-11 | 2013-11-27 | 霍夫曼-拉罗奇有限公司 | 表面表达蛋白酶作为慢性阻塞性肺病（copd）的标志物 |
| CN102435748B (zh) * | 2011-11-25 | 2014-07-16 | 广东药学院 | 一种双抗夹心酶联免疫检测试剂盒及其制备方法 |
| EP3540440B1 (de) | 2011-12-08 | 2022-09-28 | Astute Medical, Inc. | Verfahren und verwendungen zur bewertung von nierenschäden und nierenstatus |
| AU2013284448B2 (en) | 2012-06-27 | 2019-04-18 | Berg Llc | Use of markers in the diagnosis and treatment of prostate cancer |
| JP6404824B2 (ja) | 2012-11-09 | 2018-10-17 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 循環腫瘍細胞のインビトロでの捕捉および解析 |
| JP2016507723A (ja) * | 2012-11-30 | 2016-03-10 | アプライド・プロテオミクス，インコーポレイテッド | 結腸腫瘍の存在またはリスクの評価方法 |
| EP3361255B1 (de) | 2013-01-17 | 2020-03-11 | Astute Medical, Inc. | Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz |
| US9753037B2 (en) | 2013-03-15 | 2017-09-05 | Rush University Medical Center | Biomarker panel for detecting lung cancer |
| CN103267852B (zh) * | 2013-05-15 | 2015-03-25 | 中国医学科学院北京协和医院 | 成纤维激活蛋白α在制备胰腺癌预后试剂盒中的用途 |
| KR101619122B1 (ko) | 2013-08-14 | 2016-05-10 | 연세대학교 산학협력단 | 탈메틸화 의존적 ａｓｃ 발현을 촉진시켜서 대장암 종양세포의 사멸감수성을 증진시키는 항암제 병용 투여용 후보물질의 스크리닝 방법 |
| WO2015088947A1 (en) | 2013-12-09 | 2015-06-18 | Rush University Medical Center | Biomarkers of rapid progression in advanced non-small cell lung cancer |
| PL230661B1 (pl) * | 2014-01-29 | 2018-11-30 | Centrum Onkologii Inst Im Marii Sklodowskiej Curie Oddzial W Gliwicach | Metoda predykcyjna in vitro do przewidywania i/lub wykluczenia obecnosci raka pluc, zastosowanie in vitro metody predykcyjnej oraz zestaw testowy do wykrywania in vitro raka pluc |
| EP2916134B1 (de) | 2014-03-05 | 2017-08-16 | Roche Diagnostics GmbH | Verwendung von Seprase zur Differenzialdiagnose von akuter Atemnot |
| KR102657306B1 (ko) | 2014-12-08 | 2024-04-12 | 버그 엘엘씨 | 전립선암의 진단 및 치료에서 필라민을 포함하는 마커의 용도 |
| WO2016146174A1 (en) * | 2015-03-17 | 2016-09-22 | Biontech Ag | Compositions and methods for diagnosis and treatment of cancer |
| US9689874B2 (en) | 2015-04-10 | 2017-06-27 | Applied Proteomics, Inc. | Protein biomarker panels for detecting colorectal cancer and advanced adenoma |
| JP2018035137A (ja) | 2016-07-13 | 2018-03-08 | マブイミューン ダイアグノスティックス エイジーＭａｂｉｍｍｕｎｅ Ｄｉａｇｎｏｓｔｉｃｓ Ａｇ | 新規な抗線維芽細胞活性化タンパク質（ｆａｐ）結合薬剤およびその使用 |
| CA3029926C (en) * | 2016-07-25 | 2023-01-03 | Shizuoka Prefecture | Diagnostic biomarker for extrahepatic bile duct cancer, intrahepatic bile duct cancer or gallbladder cancer |
| CN116474108A (zh) | 2016-12-14 | 2023-07-25 | 普渡研究基金会 | 成纤维细胞活化蛋白(fap)-靶向成像和治疗 |
| DE102017010455A1 (de) * | 2017-06-13 | 2018-12-13 | Forschungszentrum Jülich GmbH | Verfahren zum Nachweis von Aggregaten biotherapeutischer Substanzen in einer Probe |
| US20210231669A1 (en) * | 2017-09-05 | 2021-07-29 | Oncotag Diagnotics Co., LTD | Method for diagnosing pancreatic cancer using methionyl-trna synthetase, and pancreatic cancer diagnostic kit using same |
| WO2022007283A1 (zh) * | 2020-07-08 | 2022-01-13 | 深圳霁因生物医药转化研究院 | 用于诊断fap表达异常相关疾病的试剂盒、方法及计算机可读存储介质 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0953639A1 (de) * | 1998-04-30 | 1999-11-03 | Boehringer Ingelheim International GmbH | FAPalpha-spezifischer Antikörper mit verbesserter Produzierbarkeit |
| CN104531529A (zh) * | 2003-10-31 | 2015-04-22 | 维特克公司 | 用于检测循环肿瘤和内皮细胞的血液测试样机和方法 |
| JP2008517914A (ja) * | 2004-10-22 | 2008-05-29 | ジェネンコー・インターナショナル・インク | ヒトの抗体の分離方法 |
| EP1760076A1 (de) * | 2005-09-02 | 2007-03-07 | Ferring B.V. | FAP Inhibitoren |
| CA2633803A1 (en) * | 2005-12-19 | 2007-09-07 | Trustees Of Tufts College | Soft protease inhibitors and pro-soft forms thereof |
-
2008
- 2008-12-08 AT AT08859952T patent/ATE524740T1/de active
- 2008-12-08 AU AU2008335855A patent/AU2008335855B2/en not_active Ceased
- 2008-12-08 WO PCT/EP2008/010385 patent/WO2009074275A1/en not_active Ceased
- 2008-12-08 CA CA2706115A patent/CA2706115A1/en not_active Abandoned
- 2008-12-08 MX MX2010004671A patent/MX2010004671A/es active IP Right Grant
- 2008-12-08 JP JP2010537302A patent/JP5563988B2/ja not_active Expired - Fee Related
- 2008-12-08 EP EP08859952A patent/EP2223115B1/de active Active
- 2008-12-08 KR KR1020107012678A patent/KR101202220B1/ko not_active Expired - Fee Related
- 2008-12-08 DK DK08859952.7T patent/DK2223115T3/da active
- 2008-12-08 PL PL08859952T patent/PL2223115T3/pl unknown
- 2008-12-08 CN CN200880119930.1A patent/CN101896818B/zh active Active
- 2008-12-08 ES ES08859952T patent/ES2372442T3/es active Active
- 2008-12-08 BR BRPI0820793-3A patent/BRPI0820793A2/pt not_active IP Right Cessation
-
2010
- 2010-06-02 US US12/791,946 patent/US8980573B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| HK1150884A1 (zh) | 2012-01-13 |
| JP5563988B2 (ja) | 2014-07-30 |
| KR101202220B1 (ko) | 2012-11-16 |
| WO2009074275A1 (en) | 2009-06-18 |
| PL2223115T3 (pl) | 2012-02-29 |
| ES2372442T3 (es) | 2012-01-19 |
| DK2223115T3 (da) | 2011-12-12 |
| KR20100091212A (ko) | 2010-08-18 |
| CN101896818B (zh) | 2016-01-20 |
| AU2008335855A1 (en) | 2009-06-18 |
| JP2011506941A (ja) | 2011-03-03 |
| AU2008335855B2 (en) | 2012-08-30 |
| EP2223115A1 (de) | 2010-09-01 |
| US20100240081A1 (en) | 2010-09-23 |
| CA2706115A1 (en) | 2009-06-18 |
| MX2010004671A (es) | 2010-05-27 |
| CN101896818A (zh) | 2010-11-24 |
| US8980573B2 (en) | 2015-03-17 |
| EP2223115B1 (de) | 2011-09-14 |
| BRPI0820793A2 (pt) | 2015-06-16 |
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| UEP | Publication of translation of european patent specification |
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