YU51202A - Postupak za dobijanje acetil-amidiniofenilalanil-cikloheksilglicil-piridinioalaninamida - Google Patents

Postupak za dobijanje acetil-amidiniofenilalanil-cikloheksilglicil-piridinioalaninamida

Info

Publication number
YU51202A
YU51202A YU51202A YUP51202A YU51202A YU 51202 A YU51202 A YU 51202A YU 51202 A YU51202 A YU 51202A YU P51202 A YUP51202 A YU P51202A YU 51202 A YU51202 A YU 51202A
Authority
YU
Yugoslavia
Prior art keywords
salt
amidiniophenylalanyl
cyclohexylglycyl
acetyl
preparation
Prior art date
Application number
YU51202A
Other languages
English (en)
Serbo-Croatian (sh)
Inventor
Gerhard Breipohl
Wolfgang Holla
Heiner Jendralla
Gerhard Beck
Original Assignee
Aventis Pharma Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh. filed Critical Aventis Pharma Deutschland Gmbh.
Publication of YU51202A publication Critical patent/YU51202A/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
YU51202A 2000-01-28 2001-01-18 Postupak za dobijanje acetil-amidiniofenilalanil-cikloheksilglicil-piridinioalaninamida YU51202A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10003586 2000-01-28

Publications (1)

Publication Number Publication Date
YU51202A true YU51202A (sh) 2005-11-28

Family

ID=7628946

Family Applications (1)

Application Number Title Priority Date Filing Date
YU51202A YU51202A (sh) 2000-01-28 2001-01-18 Postupak za dobijanje acetil-amidiniofenilalanil-cikloheksilglicil-piridinioalaninamida

Country Status (29)

Country Link
US (2) US20010031858A1 (cg-RX-API-DMAC7.html)
EP (1) EP1254159B9 (cg-RX-API-DMAC7.html)
JP (1) JP4778181B2 (cg-RX-API-DMAC7.html)
KR (1) KR100758141B1 (cg-RX-API-DMAC7.html)
CN (1) CN1176104C (cg-RX-API-DMAC7.html)
AR (1) AR027246A1 (cg-RX-API-DMAC7.html)
AT (1) ATE325810T1 (cg-RX-API-DMAC7.html)
AU (1) AU779722B2 (cg-RX-API-DMAC7.html)
BR (1) BR0107804A (cg-RX-API-DMAC7.html)
CA (1) CA2398497C (cg-RX-API-DMAC7.html)
CZ (1) CZ20022583A3 (cg-RX-API-DMAC7.html)
DE (1) DE60119491T2 (cg-RX-API-DMAC7.html)
DK (1) DK1254159T3 (cg-RX-API-DMAC7.html)
EE (1) EE200200410A (cg-RX-API-DMAC7.html)
ES (1) ES2262632T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20020631A2 (cg-RX-API-DMAC7.html)
HU (1) HUP0301986A2 (cg-RX-API-DMAC7.html)
IL (2) IL150897A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA02006762A (cg-RX-API-DMAC7.html)
NO (1) NO20023577L (cg-RX-API-DMAC7.html)
NZ (1) NZ520427A (cg-RX-API-DMAC7.html)
PL (1) PL356801A1 (cg-RX-API-DMAC7.html)
PT (1) PT1254159E (cg-RX-API-DMAC7.html)
RU (1) RU2250212C2 (cg-RX-API-DMAC7.html)
SK (1) SK10842002A3 (cg-RX-API-DMAC7.html)
TW (1) TWI236481B (cg-RX-API-DMAC7.html)
WO (1) WO2001055175A2 (cg-RX-API-DMAC7.html)
YU (1) YU51202A (cg-RX-API-DMAC7.html)
ZA (1) ZA200205990B (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH695999A5 (de) 2002-02-28 2006-11-15 Wilex Ag Verfahren zur Herstellung von 3- Amidinophenylalanin-Derivaten.
WO2007065691A2 (en) * 2005-12-07 2007-06-14 Technische Universität München Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
CN101774942B (zh) * 2010-01-27 2012-08-22 宁波武盛化学有限公司 制备n-乙酰基-dl-环己基甘氨酸的方法
EP2560493B1 (en) * 2010-04-20 2018-06-06 Chiral Quest, Inc. An enantioselective process for cycloalkenyl b-substituted alanines
JP5913352B2 (ja) * 2010-11-29 2016-04-27 高砂香料工業株式会社 不斉水素化触媒、およびそれを用いた光学活性カルボニル化合物の製造方法
CN115068469B (zh) * 2022-07-08 2024-02-27 深圳市小分子新药创新中心有限公司 Tigit抑制剂及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2916711A1 (de) 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
US4623717A (en) * 1980-03-05 1986-11-18 Miles Laboratories, Inc. Pasteurized therapeutically active protein compositions
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
RU2134695C1 (ru) * 1993-10-15 1999-08-20 Рон-Пуленк Рорер Фармасьютикалз Инк. Антитромботические азациклоалкилалканоилпептиды
US5849510A (en) 1994-04-26 1998-12-15 Selectide Corporation Factor Xa inhibitors
EP1384725A3 (en) * 1994-04-26 2007-02-21 Aventis Pharmaceuticals Inc. Factor Xa inhibitors
IL125003A (en) * 1995-12-20 2001-12-23 Aventis Pharma Inc Process for the preparation of N-ACETYL- (L) - 4-CYANOPHENYLALANINE AC- (L) -PHE (4-CN) -OH and for the preparation of N-ACETYL- (L) -P- AMIDINOPHENYLALANINE- CYCLOHEXYLGYLCINE-3 C) - N-METHYLPYRID) ALANINE AC (L) -PAPH-CHG- PALME (3) -NH2
DE19856443A1 (de) 1998-12-08 2000-06-21 Centeon Pharma Gmbh Stabilisiertes Antithrombin III-Präparat

Also Published As

Publication number Publication date
NO20023577D0 (no) 2002-07-26
BR0107804A (pt) 2002-10-22
DK1254159T3 (da) 2006-09-11
HK1051866A1 (en) 2003-08-22
TWI236481B (en) 2005-07-21
AU4051601A (en) 2001-08-07
CN1396928A (zh) 2003-02-12
NZ520427A (en) 2004-02-27
EP1254159B9 (en) 2006-06-28
HRP20020631A2 (en) 2004-12-31
CN1176104C (zh) 2004-11-17
WO2001055175A3 (en) 2002-02-21
AR027246A1 (es) 2003-03-19
US20040225109A1 (en) 2004-11-11
ATE325810T1 (de) 2006-06-15
WO2001055175A2 (en) 2001-08-02
JP4778181B2 (ja) 2011-09-21
CA2398497C (en) 2011-04-26
AU779722B2 (en) 2005-02-10
JP2003523364A (ja) 2003-08-05
RU2250212C2 (ru) 2005-04-20
SK10842002A3 (sk) 2003-04-01
US20010031858A1 (en) 2001-10-18
DE60119491T2 (de) 2006-11-16
IL150897A0 (en) 2003-02-12
IL150897A (en) 2008-08-07
HUP0301986A2 (hu) 2003-09-29
ES2262632T3 (es) 2006-12-01
MXPA02006762A (es) 2002-10-23
ZA200205990B (en) 2003-04-30
KR100758141B1 (ko) 2007-09-13
KR20030019306A (ko) 2003-03-06
RU2002123046A (ru) 2004-01-10
DE60119491D1 (de) 2006-06-14
CZ20022583A3 (cs) 2002-10-16
PT1254159E (pt) 2006-07-31
CA2398497A1 (en) 2001-08-02
EP1254159A2 (en) 2002-11-06
EP1254159B1 (en) 2006-05-10
PL356801A1 (en) 2004-07-12
US7084250B2 (en) 2006-08-01
NO20023577L (no) 2002-08-28
EE200200410A (et) 2003-12-15

Similar Documents

Publication Publication Date Title
EP1807412A1 (en) Cyclic diarly ureas suitable as tyrosine kinase inhibitors
WO2002055519A3 (en) Novel process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2r, 4r)-4-hydroxy -6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1h-pyrrole-3-carboxylic acid phenylamide
BRPI0111596B8 (pt) Composto piridona, processo de produção do composto, composição farmacêutica, e uso do dito composto
BRPI0418245B8 (pt) composto derivado de nitróxi de prostaglandina, processo para preparar dito composto, composição farmacêutica compreendendo dito composto e usos destes
NZ513639A (en) Cyclic protein tyrosine kinase inhibitors
DE69712784D1 (de) Säureadditionssalze einer optisch aktiven piperidinverbindung und verfahren zu seiner herstellung
NO20055370L (no) Alfa-substituert karboksylsyre som PPAR modulatorer
YU51202A (sh) Postupak za dobijanje acetil-amidiniofenilalanil-cikloheksilglicil-piridinioalaninamida
DE60134472D1 (de) Oxidationsverfahren zur herstellung des zwischenproduktes 6.alpha.,9.alpha.-difluoro-11.beta.,17.alpone 17.beta.-karbonsäure
DE60228724D1 (de) Verfahren zur herstellung von beraprost und dessen salzen
DE50113943D1 (de) 4-alkoxy-cyclohexan-1-amino-carbonsäureester und verfahren zu ihrer herstellung
DE69915713D1 (de) Verfahren zur herstellung von citalopram
ATE457972T1 (de) Verfahren zur herstellung von 7-amino-syn-3,5- dihydroxyheptansäurederivaten und zwischenverbindungen diesesverfahrens und deren herestellung
EP1640373A4 (en) PROCESS FOR PREPARING A 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE
DE602004008496D1 (de) Verfahren zur herstellung von (s)-glyceraldehydacetonid
KR20010040681A (ko) Pde iv 억제용 피리딘 유도체
WO2001081298A3 (en) Cyclic carboxylic acids as integrin antagonists
ATE266635T1 (de) Verfahren zur herstellung von zofenopril- calciumsalz
WO2002012887A3 (en) Methods and compositions for the diagnosis and treatment of brown adipose cell disorders
SU900812A3 (ru) Способ получени гидрохлорида 6,7-диметокси-4-амино-2-[4-(2-фуроил)-1-пиперазинил-ХИНАЗОЛИНА
WO2002098843A3 (en) Certain salts of discodermolide acid, pharmaceutical compositions containing them and their use in treating tumors
RU2003132433A (ru) Способ получения 2-[5-(4-фторфенил)-3- пиридилметиламинометил]хромана
CA2397960A1 (en) Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith
WO2002030874A3 (en) Aliphatic, cyclic amino carboxylic acids as integrin antagonists
ZA200100238B (en) Bispiperidines as antithrombotic agents.