YU44599B - Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals - Google Patents

Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals

Info

Publication number
YU44599B
YU44599B YU1592/86A YU159286A YU44599B YU 44599 B YU44599 B YU 44599B YU 1592/86 A YU1592/86 A YU 1592/86A YU 159286 A YU159286 A YU 159286A YU 44599 B YU44599 B YU 44599B
Authority
YU
Yugoslavia
Prior art keywords
deoxo
aza
dihydroeritromicine
dihydroerythromycin
methyl
Prior art date
Application number
YU1592/86A
Other languages
English (en)
Other versions
YU159286A (en
Inventor
Z Vajtner
N Lopotar
S Djokic
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Priority to YU1592/86A priority Critical patent/YU44599B/xx
Priority to SI8611592A priority patent/SI8611592A8/sl
Priority to AT87112902T priority patent/ATE78260T1/de
Priority to ES87112902T priority patent/ES2051717T3/es
Priority to EP87112902A priority patent/EP0259789B1/en
Priority to DE8787112902T priority patent/DE3780382T2/de
Priority to CA000546471A priority patent/CA1303028C/en
Priority to US07/094,555 priority patent/US4963528A/en
Priority to JP62226756A priority patent/JPH0633310B2/ja
Priority to CN87106924A priority patent/CN1019977C/zh
Priority to HU874047A priority patent/HU198507B/hu
Priority to PL1987267709A priority patent/PL149157B1/pl
Priority to SU874203302A priority patent/SU1572416A3/ru
Priority to CS876619A priority patent/CS265247B2/cs
Priority to DD87306907A priority patent/DD279483A5/de
Publication of YU159286A publication Critical patent/YU159286A/xx
Publication of YU44599B publication Critical patent/YU44599B/xx
Priority to HRP-1592/86A priority patent/HRP930887B1/xx
Priority to BA970165A priority patent/BA97165B1/bs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU1592/86A 1986-09-12 1986-09-12 Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals YU44599B (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
YU1592/86A YU44599B (en) 1986-09-12 1986-09-12 Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals
SI8611592A SI8611592A8 (en) 1986-09-12 1986-09-12 Process for preparing complexes of N-methyl-11-aza-10-deoxo-10-dihydroeritromicine A and 11-aza-10-deoxo-10-dihydroeritromicine A with metals
AT87112902T ATE78260T1 (de) 1986-09-12 1987-09-03 Metall komplexe von n-methyl-11-aza-10-deoxy-10dihydroerythromycin-a oder von 11-aza-10-deoxy-10-dihydroxyerythromycin-a, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen praeparaten.
ES87112902T ES2051717T3 (es) 1986-09-12 1987-09-03 Un complejo de n-metil-11-aza-10-desoxo-10-dihidroeritromicina a u 11-aza-10-desoxo-10-dihidroeritromicina a, metodo para su fabricacion y su uso en la manufactura de productos farmaceuticos.
EP87112902A EP0259789B1 (en) 1986-09-12 1987-09-03 Metal complexes of n-methyl-11-aza-10-deoxo-10-dihydro-erythromycin a or 11-aza-10-deoxo-10-dihydroerythromycin a, method for the manufacture thereof and their use in the manufacture of pharmaceuticals
DE8787112902T DE3780382T2 (de) 1986-09-12 1987-09-03 Metall komplexe von n-methyl-11-aza-10-deoxy-10-dihydroerythromycin-a oder von 11-aza-10-deoxy-10-dihydroxyerythromycin-a, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen praeparaten.
CA000546471A CA1303028C (en) 1986-09-12 1987-09-09 Metal complexes of n-methyl-11-aza-10-deoxo-10- dihydroerythromycina or 11-aza-10-deoxo-10- dihydroerythromycin a, method for the manufacture thereof and their use in the manufacture of pharmaceuticals
US07/094,555 US4963528A (en) 1986-09-12 1987-09-09 Metal complexes of N-methyl-11-aza-10-deoxo-10-dihydro-erythromycin A or 11-aza-10-deoxo-10-dihydro-erythromycin A, method for the manufacture thereof and their use in the manufacture of pharmaceuticals
CN87106924A CN1019977C (zh) 1986-09-12 1987-09-11 N-甲基-11-氮杂-10-脱氧-10-二氢红霉素a和11-氮杂-10脱氧-10-二氢红霉素a的金属的制备方法
JP62226756A JPH0633310B2 (ja) 1986-09-12 1987-09-11 １１−アザ−１０−デオキソ−１０−ジヒドロエリスロマイシンａ又はそのｎ−メチル誘導体の金属錯塩及びそれらの製造法
HU874047A HU198507B (en) 1986-09-12 1987-09-11 Process for producing metal complexes of 11-aza-10-deoxo-10-dihydro-erythromycin-a derivatives and pharmaceutical compositions comprising these compouharmaceutical nds as active ingredient
PL1987267709A PL149157B1 (en) 1986-09-12 1987-09-11 The method of manufacture of organometallic compounds of n-methyl-11-aza-10-dezketon-10-dihydroerythromycin a
SU874203302A SU1572416A3 (ru) 1986-09-12 1987-09-11 Способ получени металлических комплексов производных эритромицина А с двухвалентными металлами С @ , Z @ , С @ , N @ или С @ в соотношении 2:1, про вл ющих бактерицидную активность
CS876619A CS265247B2 (en) 1986-09-12 1987-09-11 Process for preparing metal complexes of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a or 11-aza-10-deoxo-10-dihydroerythromicine a
DD87306907A DD279483A5 (de) 1986-09-12 1987-09-11 Verfahren zur herstellung von metallkomplexen des n-methyl-11-aza-10-deoxo-10-dihydroerythromycins a und 11-aza-10-deoxo-10-dihydroerythomycins a
HRP-1592/86A HRP930887B1 (en) 1986-09-12 1993-05-13 Process for the preparation of complex n-methyl-11-aza-10-deoxo-10-dihydroerythromicin a and 11-aza-10-deoxo-10-dihydroerythromycin a with metals
BA970165A BA97165B1 (bs) 1986-09-12 1997-04-25 Postupak za pripravu kompleksa n-metil-11-aza-10-dihidroeritromecina a i 11-aza-10-deokso-10-dihidroeritromicina a s metalima

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU1592/86A YU44599B (en) 1986-09-12 1986-09-12 Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals

Publications (2)

Publication Number Publication Date
YU159286A YU159286A (en) 1988-06-30
YU44599B true YU44599B (en) 1990-10-31

Family

ID=25554798

Family Applications (1)

Application Number Title Priority Date Filing Date
YU1592/86A YU44599B (en) 1986-09-12 1986-09-12 Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals

Country Status (16)

Country Link
US (1) US4963528A (ja)
EP (1) EP0259789B1 (ja)
JP (1) JPH0633310B2 (ja)
CN (1) CN1019977C (ja)
AT (1) ATE78260T1 (ja)
BA (1) BA97165B1 (ja)
CA (1) CA1303028C (ja)
CS (1) CS265247B2 (ja)
DD (1) DD279483A5 (ja)
DE (1) DE3780382T2 (ja)
ES (1) ES2051717T3 (ja)
HU (1) HU198507B (ja)
PL (1) PL149157B1 (ja)
SI (1) SI8611592A8 (ja)
SU (1) SU1572416A3 (ja)
YU (1) YU44599B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU45590A (sh) * 1990-03-07 1992-07-20 PLIVA FARMACEVTSKA, KEMIJSKA, PREHRAMBENA I KOZMETIČKA INDUSTRIJA s.p.o. Novi kompleksi odnosno helati antibiotika s dvovalentnim i/ili trovalentnim metalima i postupci za njihovo dobijanje
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
CN1045097C (zh) * 1995-03-22 1999-09-15 武汉市高校新技术研究所 高氯化聚乙烯带锈防锈防腐漆及其制造方法
UA70972C2 (uk) * 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків
US6764996B1 (en) 1999-08-24 2004-07-20 Abbott Laboratories 9a-azalides with antibacterial activity
DK1206476T3 (da) * 1999-08-24 2006-05-15 Abbott Lab 9a-azalider med antibakteriel virkning

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
JPS5750996A (en) * 1980-09-11 1982-03-25 Microbial Chem Res Found 3-o-demthylistamycin b derivative
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor

Also Published As

Publication number Publication date
CS265247B2 (en) 1989-10-13
EP0259789A3 (en) 1989-11-15
SU1572416A3 (ru) 1990-06-15
US4963528A (en) 1990-10-16
CA1303028C (en) 1992-06-09
BA97165B1 (bs) 1998-12-28
JPS6377895A (ja) 1988-04-08
PL149157B1 (en) 1990-01-31
ATE78260T1 (de) 1992-08-15
SI8611592A8 (en) 1995-04-30
JPH0633310B2 (ja) 1994-05-02
PL267709A1 (en) 1988-09-01
HU198507B (en) 1989-10-30
EP0259789B1 (en) 1992-07-15
DE3780382T2 (de) 1992-12-17
EP0259789A2 (en) 1988-03-16
DE3780382D1 (de) 1992-08-20
ES2051717T3 (es) 1994-07-01
YU159286A (en) 1988-06-30
CN87106924A (zh) 1988-06-01
HUT47589A (en) 1989-03-28
CN1019977C (zh) 1993-03-03
DD279483A5 (de) 1990-06-06
CS661987A2 (en) 1989-01-12

Similar Documents

Publication Publication Date Title
YU159286A (en) Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals
EP0351865A3 (en) Dc-89 compounds and process for their preparation
YU54189A (en) Process for obtaining cephem derivatives and midproducts for the same
GR3002539T3 (en) Hydroxy-alkylazolyl derivatives
IL55728A0 (en) Novel 2-arylamino-hexahydtropyrimidines and imidazolidines,their salts and complexes thereof,their preparation and fungicidal compositions containing them
MY110352A (en) Process for preparing 4-demethoxydaunorubicin.
GB1458251A (en) 1-phenyl-2-amino-ethanol derivatives
MX9604338A (es) Benzoilguanidinas sustituidas, procedimiento para su preparacion, su utilizacion como medicamento o agente de diagnostico, asi como medicamento que las contiene.
GB1215676A (en) Fungicidal compositions
YU198286A (en) Process for preparing complex of n-acethyl-glucosis-minyl-n-acethyl-muramoil-l-alanyl-d-izoglutaminyl-(l)-mezodiaminopimelyl-(d-amid)-(l)-alanyl-d-
EP0024508A3 (en) Antibiotic bm123-gamma pamoate complexes, process for their preparation and compositions containing them
ES8605261A1 (es) Un procedimiento para la preparacion de 1,4-aminoalquilamino-9-h-tioxaten-9-onas.
GB1461558A (en) Spasmium salt
DE3480542D1 (en) Cephem compounds
LTIP1788A (en) Novel acrylic acid salts, a process for their preparation, pharmaceutical compositions containing them and their use in medicine
MY106890A (en) Process for producing n-phosphonomethylglcine.
FR2182273A5 (en) Zinc-contng metallic alkylenebis-dithiocarbamate-ethylene - polyamine complexes - antifungal plant growth promoters
GB1269451A (en) Antimicrobially active substances and their production
NL7204818A (en) Zinc-contng metallic alkylenebis-dithiocarbamate-ethylene - polyamine complexes - antifungal plant growth promoters
ES444234A1 (es) Un procedimiento de preparacion de nuevas dibiciclo-heptenil-poliaminas.
RO91935B1 (ro) Procedeu de obtinere a unor n, n-dialchilaminoalchilamine
ES405105A1 (es) Un procedimiento para la preparacion de 2,6,6-trimetil-1-(10' - carboxi - 3',7'-dimetil - deca - 1',3',5',7',9' - pen- taenil)-cicolhexi-eno o una sal del mismo.
HUT38323A (en) Microbicide compositions containing organic complex compounds as active substances and process for preparing the active substances
GR62551B (en) Preparation process of alkaly or ammonium salts of bis-(thiazolidin-4-carboxylic)acid zinc dithiocarbamate,a fungicide stimulating the growth of the plants
GB1355097A (en) Pesticidal and pharmaceutical compositions