GB1458251A - 1-phenyl-2-amino-ethanol derivatives - Google Patents

1-phenyl-2-amino-ethanol derivatives

Info

Publication number
GB1458251A
GB1458251A GB905874A GB905874A GB1458251A GB 1458251 A GB1458251 A GB 1458251A GB 905874 A GB905874 A GB 905874A GB 905874 A GB905874 A GB 905874A GB 1458251 A GB1458251 A GB 1458251A
Authority
GB
United Kingdom
Prior art keywords
phenyl
amino
methylpropyl
hydroxybutyl
ethanol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB905874A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of GB1458251A publication Critical patent/GB1458251A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems

Abstract

1458251 Compositions containing aminoethanols BASF AG 28 Feb 1974 [1 March 1973] 9058/74 Heading A5B [Also in Division C2] Pharmaceutical compositions comprise a compound of the general formula: (R<SP>1</SP> = 2-methylbutyl-2, 1-hydroxybutyl-2, 1-hydroxybutyl-3, 1-methoxybutyl-3, 1, 1-diphenylbutyl-3, 1-methoxy-2-methylpropyl-2, 1-methylthio-2-methylpropyl, 2-cyanopropyl-2, 1-dimethylaminopropyl-3, 1-dimethylamino-2, 2- dimethylpropyl-3, 1-dimethylaminohexyl - 6, cyclopropyl, cyclobutyl, 1-methylcyclopropyl, 1-methylcyclopentyl, 1-cyclopropylethyl) or salt thereof in association with a carrier. The active ingredients are bronchodilators.
GB905874A 1973-03-01 1974-02-28 1-phenyl-2-amino-ethanol derivatives Expired GB1458251A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732310141 DE2310141A1 (en) 1973-03-01 1973-03-01 PROCESS FOR THE PREPARATION OF 1PHENYL-2-AMINOAETHANOL DERIVATIVES

Publications (1)

Publication Number Publication Date
GB1458251A true GB1458251A (en) 1976-12-15

Family

ID=5873455

Family Applications (1)

Application Number Title Priority Date Filing Date
GB905874A Expired GB1458251A (en) 1973-03-01 1974-02-28 1-phenyl-2-amino-ethanol derivatives

Country Status (8)

Country Link
JP (1) JPS49134638A (en)
AT (1) AT334335B (en)
BE (1) BE811754A (en)
CH (1) CH599111A5 (en)
DE (1) DE2310141A1 (en)
FR (1) FR2219931B3 (en)
GB (1) GB1458251A (en)
NL (1) NL7402660A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154761A (en) * 1976-02-09 1979-05-15 Allen & Hanburys Limited Pharmacologically active compounds
US7964615B2 (en) 2005-05-20 2011-06-21 Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the β2 adrenergic receptor
US8178679B2 (en) 2007-11-28 2012-05-15 Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the β2 adrenergic receptors
US8283342B2 (en) 2007-02-09 2012-10-09 Almirall S.A. Napadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one as agonist of the β2 adrenergic receptor
US8524908B2 (en) 2009-03-12 2013-09-03 Almirall, S.A. Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
US8563731B2 (en) 2008-12-22 2013-10-22 Almirall, S.A. Mesylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]jamino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one as agonist of the β2 adrenergic receptor
CN103951568A (en) * 2014-05-19 2014-07-30 苏州弘森药业有限公司 New process for synthesizing salbutamol and sulfate of salbutamol
US9108918B2 (en) 2011-10-07 2015-08-18 Almirall, S.A. Process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(R)-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one via a novel intermediate
US9346759B2 (en) 2012-03-20 2016-05-24 Almirall, S.A. Polymorphic crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one, heminapadisytlate as agonist of the β2 adrenergic receptor
CN110963929A (en) * 2019-11-26 2020-04-07 安徽恒星制药有限公司 Preparation method of salbutamol hydrochloride suitable for industrial production

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5328899B2 (en) * 1973-09-11 1978-08-17
US4633019A (en) * 1981-09-14 1986-12-30 Petrolite Corporation α-aminoalkylsulfur compositions

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154761A (en) * 1976-02-09 1979-05-15 Allen & Hanburys Limited Pharmacologically active compounds
US7964615B2 (en) 2005-05-20 2011-06-21 Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the β2 adrenergic receptor
US8242177B2 (en) 2005-05-20 2012-08-14 Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the β2 adrenergic receptor
US8420669B2 (en) 2005-05-20 2013-04-16 Laboratories Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the BETA2 adrenergic receptor
US8283342B2 (en) 2007-02-09 2012-10-09 Almirall S.A. Napadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one as agonist of the β2 adrenergic receptor
US8178679B2 (en) 2007-11-28 2012-05-15 Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the β2 adrenergic receptors
US8563731B2 (en) 2008-12-22 2013-10-22 Almirall, S.A. Mesylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]jamino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one as agonist of the β2 adrenergic receptor
US8524908B2 (en) 2009-03-12 2013-09-03 Almirall, S.A. Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
US9108918B2 (en) 2011-10-07 2015-08-18 Almirall, S.A. Process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(R)-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one via a novel intermediate
US9346759B2 (en) 2012-03-20 2016-05-24 Almirall, S.A. Polymorphic crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one, heminapadisytlate as agonist of the β2 adrenergic receptor
CN103951568A (en) * 2014-05-19 2014-07-30 苏州弘森药业有限公司 New process for synthesizing salbutamol and sulfate of salbutamol
CN103951568B (en) * 2014-05-19 2015-10-28 苏州弘森药业有限公司 A kind of novel process of synthesizing salbutamol and vitriol thereof
CN110963929A (en) * 2019-11-26 2020-04-07 安徽恒星制药有限公司 Preparation method of salbutamol hydrochloride suitable for industrial production
CN110963929B (en) * 2019-11-26 2022-10-21 安徽恒星制药有限公司 Preparation method of salbutamol hydrochloride suitable for industrial production

Also Published As

Publication number Publication date
FR2219931A1 (en) 1974-09-27
JPS49134638A (en) 1974-12-25
BE811754A (en) 1974-09-02
FR2219931B3 (en) 1976-12-10
AT334335B (en) 1976-01-10
ATA164274A (en) 1976-05-15
CH599111A5 (en) 1978-05-12
DE2310141A1 (en) 1974-09-12
NL7402660A (en) 1974-09-03

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee