ATE78260T1 - Metall komplexe von n-methyl-11-aza-10-deoxy-10dihydroerythromycin-a oder von 11-aza-10-deoxy-10-dihydroxyerythromycin-a, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen praeparaten. - Google Patents

Metall komplexe von n-methyl-11-aza-10-deoxy-10dihydroerythromycin-a oder von 11-aza-10-deoxy-10-dihydroxyerythromycin-a, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen praeparaten.

Info

Publication number
ATE78260T1
ATE78260T1 AT87112902T AT87112902T ATE78260T1 AT E78260 T1 ATE78260 T1 AT E78260T1 AT 87112902 T AT87112902 T AT 87112902T AT 87112902 T AT87112902 T AT 87112902T AT E78260 T1 ATE78260 T1 AT E78260T1
Authority
AT
Austria
Prior art keywords
aza
deoxy
methyl
dihydroerythromycin
deoxo
Prior art date
Application number
AT87112902T
Other languages
English (en)
Inventor
Zlatko Dr Vajtner
Nevenka Lopotar
Slobodan Dr Djokic
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Application granted granted Critical
Publication of ATE78260T1 publication Critical patent/ATE78260T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT87112902T 1986-09-12 1987-09-03 Metall komplexe von n-methyl-11-aza-10-deoxy-10dihydroerythromycin-a oder von 11-aza-10-deoxy-10-dihydroxyerythromycin-a, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen praeparaten. ATE78260T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
YU1592/86A YU44599B (en) 1986-09-12 1986-09-12 Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals
EP87112902A EP0259789B1 (de) 1986-09-12 1987-09-03 Metall Komplexe von N-Methyl-11-aza-10-deoxy-10-dihydroerythromycin-A oder von 11-Aza-10-deoxy-10-dihydroxyerythromycin-A, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von pharmazeutischen Präparaten

Publications (1)

Publication Number Publication Date
ATE78260T1 true ATE78260T1 (de) 1992-08-15

Family

ID=25554798

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87112902T ATE78260T1 (de) 1986-09-12 1987-09-03 Metall komplexe von n-methyl-11-aza-10-deoxy-10dihydroerythromycin-a oder von 11-aza-10-deoxy-10-dihydroxyerythromycin-a, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen praeparaten.

Country Status (16)

Country Link
US (1) US4963528A (de)
EP (1) EP0259789B1 (de)
JP (1) JPH0633310B2 (de)
CN (1) CN1019977C (de)
AT (1) ATE78260T1 (de)
BA (1) BA97165B1 (de)
CA (1) CA1303028C (de)
CS (1) CS265247B2 (de)
DD (1) DD279483A5 (de)
DE (1) DE3780382T2 (de)
ES (1) ES2051717T3 (de)
HU (1) HU198507B (de)
PL (1) PL149157B1 (de)
SI (1) SI8611592A8 (de)
SU (1) SU1572416A3 (de)
YU (1) YU44599B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU45590A (sh) * 1990-03-07 1992-07-20 PLIVA FARMACEVTSKA, KEMIJSKA, PREHRAMBENA I KOZMETIČKA INDUSTRIJA s.p.o. Novi kompleksi odnosno helati antibiotika s dvovalentnim i/ili trovalentnim metalima i postupci za njihovo dobijanje
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
CN1045097C (zh) * 1995-03-22 1999-09-15 武汉市高校新技术研究所 高氯化聚乙烯带锈防锈防腐漆及其制造方法
UA70972C2 (uk) * 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків
US6764996B1 (en) 1999-08-24 2004-07-20 Abbott Laboratories 9a-azalides with antibacterial activity
DK1206476T3 (da) * 1999-08-24 2006-05-15 Abbott Lab 9a-azalider med antibakteriel virkning

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
JPS5750996A (en) * 1980-09-11 1982-03-25 Microbial Chem Res Found 3-o-demthylistamycin b derivative
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor

Also Published As

Publication number Publication date
CS265247B2 (en) 1989-10-13
EP0259789A3 (en) 1989-11-15
YU44599B (en) 1990-10-31
SU1572416A3 (ru) 1990-06-15
US4963528A (en) 1990-10-16
CA1303028C (en) 1992-06-09
BA97165B1 (bs) 1998-12-28
JPS6377895A (ja) 1988-04-08
PL149157B1 (en) 1990-01-31
SI8611592A8 (en) 1995-04-30
JPH0633310B2 (ja) 1994-05-02
PL267709A1 (en) 1988-09-01
HU198507B (en) 1989-10-30
EP0259789B1 (de) 1992-07-15
DE3780382T2 (de) 1992-12-17
EP0259789A2 (de) 1988-03-16
DE3780382D1 (de) 1992-08-20
ES2051717T3 (es) 1994-07-01
YU159286A (en) 1988-06-30
CN87106924A (zh) 1988-06-01
HUT47589A (en) 1989-03-28
CN1019977C (zh) 1993-03-03
DD279483A5 (de) 1990-06-06
CS661987A2 (en) 1989-01-12

Similar Documents

Publication Publication Date Title
DE69019534T2 (de) Insulinzubereitungen, die nikotinsäure oder nikotinamid enthalten.
ATE78260T1 (de) Metall komplexe von n-methyl-11-aza-10-deoxy-10dihydroerythromycin-a oder von 11-aza-10-deoxy-10-dihydroxyerythromycin-a, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen praeparaten.
CS960586A2 (en) Insekticidni a akaricidni prostredek a zpusob vyroby ucinnych latek
HUT50345A (en) Process for production of cefem-derivatives and their intermediers
IL87014A0 (en) Hydroxyalkyl-azolyl derivatives,their preparation and their use as fungicides
ATE25238T1 (de) Pharmazeutische zusammensetzungen zur behandlung von entzuendungen oder arthritis.
ES8801186A1 (es) Un procedimiento para la preparacion de amidas de aminoacido con actividad antitumoral
EP0342587A3 (de) Thienotriazolodiazepine und ihre pharmazeutische Verwendung
ATE56008T1 (de) Benzofuran-2-yl-imidazole mit pharmazeutischer wirkung, ihre salze und relevante verfahren zu ihrer herstellung.
DE3573121D1 (en) Diacylderivatives of glycerylphosphorylcholine having therapeutical activity, a process for their preparation and related pharmaceutical compositions
EP0170203A3 (de) 4H-Pyrido[2,3-d][1,3]oxazin-4-on-derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Bekämpfung unerwünschten Pflanzenwuchses
ATE85347T1 (de) Metallkomplexe von n-acetylglucosaminyl-nacetylmuramoyl-l-alanyl-d-isoglutaminyl-(l)mesodiaminopimelyl-(d-amid)-(l)-d-alanyl-d-alan n und ihre verwednung bei der herstellung von arzneimitteln''.
JPS5716855A (en) 4-guanidinomethylcyclohexanecarboxylic acid ester and its preparation
EP0152249A3 (de) 1,4-Aminoalkylamino-9H-thioxanthen-9-one, Verfahren zur Herstellung der Verbindungen, ein Zwischenprodukt bei der Herstellung der Verbindungen und diese Verbindungen enthaltende pharmazeutische Zusammensetzung
GB1461558A (en) Spasmium salt
EP0159899A3 (de) Cephalosporinester, ihre Herstellung und Verwendung
FR2603287A1 (fr) Procede de preparation de complexes de metalloproteines et nouveaux derives de ceux-ci
DE3361077D1 (en) Bis-(benzoylthio)-carboxylic acids, their preparation and use in the production of active ingredients
GB1476728A (en) Method of combating plant disease
RU93034922A (ru) Способ получения s-этилмеркуртиосалициловой кислоты
EP0132283A3 (de) Optisch aktive, fungizide Diaryltriazolyläthanole
EP0158170A3 (en) Erythromycin salt with mucosecretolytic and fluidizing activity, a process for its preparation and pharmaceutical compositions thereof
JPS5545632A (en) N-substituted alkylene-bisdithio-carbamic acid metal salt
OA05173A (fr) Nouveaux sels métalliques d'acides dithiocarbamiques mixtes, leur préparation et leur application comme fongicides.
ES2076517T3 (es) Ergolinas disustituidas en posiciones 2,13, su preparacion y utilizacion en medicamentos.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee