YU34500A - Injektabilne formulacije dugog dejstva koje sadrže hidrogenisano ricinusovo ulje - Google Patents

Injektabilne formulacije dugog dejstva koje sadrže hidrogenisano ricinusovo ulje

Info

Publication number
YU34500A
YU34500A YU34500A YU34500A YU34500A YU 34500 A YU34500 A YU 34500A YU 34500 A YU34500 A YU 34500A YU 34500 A YU34500 A YU 34500A YU 34500 A YU34500 A YU 34500A
Authority
YU
Yugoslavia
Prior art keywords
hydrogenated castor
castor oil
injectable formulations
acting injectable
formulations containing
Prior art date
Application number
YU34500A
Other languages
English (en)
Inventor
James B. Williams
Rey T. Chern
Original Assignee
Merck & Co.Inc.
Merial Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26313620&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU34500(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9809792.6A external-priority patent/GB9809792D0/en
Application filed by Merck & Co.Inc., Merial Llc filed Critical Merck & Co.Inc.
Publication of YU34500A publication Critical patent/YU34500A/sh
Publication of RS49838B publication Critical patent/RS49838B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Pronalazak se odnosi na nove, injektabilne formulacije dugog dejstva. Ove formulacije uključuju: (a) terapijske agense odabrane iz grupe koja sadrži na pr. insekticide, akaricide, paraziticide, stimulatore rasta i nesteroidne antiinflamatorne lekove rastvorljive u uljima; (b) hidrogenisano ricinusovo ulje i (c) hidrofobne nosače koji uključuju: (i) triacetin, benzil-benzoat ili etiloleat ili njihovu kombinaciju; i (ii) acilovane monogliceride, propildikaprilate/dikaprate ili trigliceride kaprilne/kaprinske kiseline ili njihovu kombinaciju. Takodje je prikazan metod za tretman ili prevenciju različitih oboljenja parenteralnom administracijom formulacija ovog pronalaska.[This invention relates to novel, long-acting injectable formulations. These formulations comprise: (a) a therapeutic agent selected from the group consisting of, e.g., insecticides, acaricides, parasiticides, growth enhancers and oil-soluble NASIDS; (b) hydrogenated castor oil and (c) a hydrophobic carrier comprising: (i) triacetin, benzyl benzoate or ethyl oleate or a combination thereof; and (ii) acylated monoglycerides, propyl dicaprylates/dicaprates or caprylic/capric acid triglycerides or a combination thereof. Also provided herein is a method for the treatment or prevention of various disease states by the parental administration of the invention formulations.
YUP-345/00A 1997-12-03 1998-09-14 Injektibilne formulacije dugog dejstva koje sadrže hidrogenisano ricinusovo ulje RS49838B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6737497P 1997-12-03 1997-12-03
GBGB9809792.6A GB9809792D0 (en) 1998-05-07 1998-05-07 Long acting injectable formulations containing hydrogenated castor oil

Publications (2)

Publication Number Publication Date
YU34500A true YU34500A (sh) 2002-11-15
RS49838B RS49838B (sr) 2008-08-07

Family

ID=26313620

Country Status (28)

Country Link
EP (1) EP1035835B1 (sh)
JP (1) JP3925900B2 (sh)
KR (1) KR100499438B1 (sh)
CN (1) CN1205921C (sh)
AR (1) AR017779A1 (sh)
AT (1) ATE249206T1 (sh)
AU (1) AU749006B2 (sh)
BG (1) BG65147B1 (sh)
BR (1) BR9815352A (sh)
CA (1) CA2312898C (sh)
CO (1) CO4970836A1 (sh)
DE (1) DE69818093T2 (sh)
DK (1) DK1035835T3 (sh)
EA (1) EA002497B1 (sh)
ES (1) ES2205550T3 (sh)
HK (1) HK1032917A1 (sh)
HR (1) HRP20000366B1 (sh)
HU (1) HU228617B1 (sh)
IL (1) IL136313A (sh)
ME (1) ME00855B (sh)
NO (1) NO329469B1 (sh)
NZ (1) NZ504783A (sh)
PL (1) PL192651B1 (sh)
PT (1) PT1035835E (sh)
RS (1) RS49838B (sh)
SK (1) SK284522B6 (sh)
TW (1) TW550088B (sh)
WO (1) WO1999027906A1 (sh)

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DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
JP4502641B2 (ja) * 2002-01-24 2010-07-14 ティルタン ファーマ リミテッド 抗癌組み合わせおよびその使用方法
CN1275589C (zh) * 2002-05-31 2006-09-20 王玉万 含抗寄生虫药物的缓释注射剂
UY27412A1 (es) * 2002-08-12 2003-06-30 Carlson Internat Inc Un nuevo producto para el combate de garrapatas y el proceso para la prepaacinn.
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
WO2004045581A1 (fr) * 2002-11-18 2004-06-03 Yuwan Wang Injection d'une suspension d'un antiparasite veterinaire
WO2004047803A1 (fr) * 2002-11-27 2004-06-10 Eco Animal Health Ltd Injection de medicament pour animaux renfermant du closantel ou du sodium de closantel
JO2505B1 (en) * 2003-03-14 2009-10-05 باير شيرنغ فارما اكتنجيسيلشافت Pharmacy methods and formulations for obtaining acceptable serum testosterone levels
TW200505425A (en) * 2003-05-29 2005-02-16 Schering Plough Ltd Compositions and method for treating infection in cattle and swine
CN1293921C (zh) * 2003-08-18 2007-01-10 王玉万 含乙基纤维素和脂肪酸酯类的长效注射剂
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
WO2005084688A1 (fr) * 2004-03-04 2005-09-15 Yuwan Wang Poudre injectable contenant un vermifuge
NZ534939A (en) * 2004-08-26 2007-04-27 Bomac Research Ltd Injectable formulation comprising an anthelmintic compound with complexing compound for improved solubility
DE102006043444A1 (de) * 2006-09-15 2008-03-27 Bayer Cropscience Ag Suspensionskonzentrate auf Ölbasis
NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
GB0804619D0 (en) * 2008-03-12 2008-04-16 Norbrook Lab Ltd A topical ectoparasiticide composition
NZ592865A (en) * 2008-11-19 2013-08-30 Merial Ltd Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof
CA2777366C (en) 2009-10-12 2023-11-14 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
MX2012010077A (es) 2010-03-03 2012-09-12 Boehringer Ingelheim Vetmed Uso de meloxicam para el tratamiento a largo plazo de trastornos musculoesqueleticos en gatos.
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
WO2014016252A1 (en) * 2012-07-27 2014-01-30 Novartis Ag New treatment of fish with a nanosus pens ion of lufenuron or hexaflumuron
BR112015013491B1 (pt) * 2012-12-12 2021-03-30 Zoetis Services Llc Composição veterinária ectoparasítica injetável e uso da mesma
FR3000392B1 (fr) 2012-12-27 2015-03-27 Virbac Nouvelles compositions pharmaceutiques veterinaires et leur procede de preparation
CN104337761B (zh) * 2013-08-07 2019-03-26 江苏豪森药业集团有限公司 氟维司群药物组合物
DK3082762T3 (da) * 2013-12-16 2021-12-06 Zoetis Services Llc Langtidsvirkende ketoprofensammensætninger
CN103721266A (zh) * 2014-01-06 2014-04-16 王玉万 含阿维菌素类药物/氢化蓖麻油的原位胶凝注射剂
JP6777734B2 (ja) * 2015-06-10 2020-10-28 ピードモント アニマル ヘルス インコーポレイテッド 注射可能な抗生物質製剤及びその使用
WO2020223959A1 (en) * 2019-05-09 2020-11-12 The Procter & Gamble Company Stable anti-mite liquid laundry detergent composition comprising benzyl benzoate
CN110585124A (zh) * 2019-09-26 2019-12-20 西安力邦医药科技有限责任公司 一种含有雌三醇或其衍生物的油性注射剂

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Also Published As

Publication number Publication date
JP3925900B2 (ja) 2007-06-06
CN1205921C (zh) 2005-06-15
ME00855B (me) 2008-08-07
SK8292000A3 (en) 2000-11-07
BR9815352A (pt) 2000-10-17
KR100499438B1 (ko) 2005-07-07
WO1999027906A1 (en) 1999-06-10
DK1035835T3 (da) 2003-12-08
CA2312898A1 (en) 1999-06-10
KR20010032760A (ko) 2001-04-25
HUP0100606A3 (en) 2002-11-28
EA200000604A1 (ru) 2000-12-25
SK284522B6 (sk) 2005-05-05
AU749006B2 (en) 2002-06-13
HUP0100606A2 (hu) 2001-06-28
NO329469B1 (no) 2010-10-25
NZ504783A (en) 2002-12-20
NO20002830D0 (no) 2000-06-02
AU9385898A (en) 1999-06-16
IL136313A0 (en) 2001-05-20
BG104560A (en) 2001-04-30
EP1035835A1 (en) 2000-09-20
PT1035835E (pt) 2003-12-31
ATE249206T1 (de) 2003-09-15
ES2205550T3 (es) 2004-05-01
NO20002830L (no) 2000-08-03
AR017779A1 (es) 2001-10-24
HRP20000366B1 (en) 2009-08-31
IL136313A (en) 2005-08-31
EP1035835B1 (en) 2003-09-10
CN1283990A (zh) 2001-02-14
DE69818093D1 (de) 2003-10-16
PL192651B1 (pl) 2006-11-30
EA002497B1 (ru) 2002-06-27
HRP20000366A2 (en) 2001-06-30
PL341542A1 (en) 2001-04-23
CO4970836A1 (es) 2000-11-07
BG65147B1 (bg) 2007-04-30
DE69818093T2 (de) 2004-06-09
TW550088B (en) 2003-09-01
HU228617B1 (en) 2013-04-29
JP2001524510A (ja) 2001-12-04
CA2312898C (en) 2004-05-11
RS49838B (sr) 2008-08-07
HK1032917A1 (en) 2001-08-10

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