JPS5655397A - Aminobenzoic acid ester derivative, and physiologically active agent containing said derivative - Google Patents

Aminobenzoic acid ester derivative, and physiologically active agent containing said derivative

Info

Publication number
JPS5655397A
JPS5655397A JP13225979A JP13225979A JPS5655397A JP S5655397 A JPS5655397 A JP S5655397A JP 13225979 A JP13225979 A JP 13225979A JP 13225979 A JP13225979 A JP 13225979A JP S5655397 A JPS5655397 A JP S5655397A
Authority
JP
Japan
Prior art keywords
aminobenzoic acid
derivative
suppressing
acid ester
active agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13225979A
Other languages
Japanese (ja)
Other versions
JPS5938960B2 (en
Inventor
Chikao Yoshikumi
Fumio Hirose
Yoshio Omura
Takami Fujii
Masanori Ubusawa
Minoru Ohara
Kenichi Matsunaga
Takao Ando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Priority to JP54132259A priority Critical patent/JPS5938960B2/en
Priority to GB8032272A priority patent/GB2060636B/en
Priority to DE3038304A priority patent/DE3038304C2/en
Priority to BE0/202404A priority patent/BE885631A/en
Publication of JPS5655397A publication Critical patent/JPS5655397A/en
Publication of JPS5938960B2 publication Critical patent/JPS5938960B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

NEW MATERIAL:The titled compound of formula (R1 is residue of saccharide selected from arabinose, xylose, mannose, glucose, galactose, and rhamnose; R2 is methyl, ethyl, propyl or butyl; excluding o-aminobenzoic acid methyl ester-N-D- mannoside).
EXAMPLE: o-Aminobenzoic acid methyl ester-N-D-xyloside.
USE: Medicine having blood sugar level suppressing, hypotensive, blood lipid suppressing, antineoplasmic, central nervous system suppressing, and antiphlogistic activities. Since it has low toxicity and no antibacterial activity, it can be administered for a long period without the danger of teratogenecity, allergic reaction, etc. Preferably administered orally.
PROCESS: The compound of formula is prepared by reacting an aminobenzoic acid ester with a saccharide in the presence of ammonium chloride, etc., in a solvent.
COPYRIGHT: (C)1981,JPO&Japio
JP54132259A 1979-10-12 1979-10-12 Aminobenzoic acid ester derivatives and pharmaceuticals containing the derivatives Expired JPS5938960B2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP54132259A JPS5938960B2 (en) 1979-10-12 1979-10-12 Aminobenzoic acid ester derivatives and pharmaceuticals containing the derivatives
GB8032272A GB2060636B (en) 1979-10-12 1980-10-07 Esters of aminobenzoic acid their preparation and compositions containing them
DE3038304A DE3038304C2 (en) 1979-10-12 1980-10-10 N-glycosides of esters of o-, m- and p-aminobenzoic acid and medicaments containing these compounds
BE0/202404A BE885631A (en) 1979-10-12 1980-10-10 NEW ESTERS OF AMINOBENZOIC ACID

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54132259A JPS5938960B2 (en) 1979-10-12 1979-10-12 Aminobenzoic acid ester derivatives and pharmaceuticals containing the derivatives

Publications (2)

Publication Number Publication Date
JPS5655397A true JPS5655397A (en) 1981-05-15
JPS5938960B2 JPS5938960B2 (en) 1984-09-20

Family

ID=15077085

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54132259A Expired JPS5938960B2 (en) 1979-10-12 1979-10-12 Aminobenzoic acid ester derivatives and pharmaceuticals containing the derivatives

Country Status (4)

Country Link
JP (1) JPS5938960B2 (en)
BE (1) BE885631A (en)
DE (1) DE3038304C2 (en)
GB (1) GB2060636B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103864638A (en) * 2012-12-14 2014-06-18 沈阳药科大学 Benzoic acid compound, and preparation method and application thereof

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0053827B1 (en) * 1980-12-09 1985-09-18 Seikagaku Kogyo Co. Ltd. D-xylopyranoside series compounds and therapeutical compositions containing same
HU203896B (en) * 1988-10-26 1991-10-28 Biogal Gyogyszergyar Process for producing glycosides of aromatic amines
WO2001068136A1 (en) * 2000-03-17 2001-09-20 Ajinomoto Co., Inc. Drugs for complications of diabetes and neuropathy and utilization thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103864638A (en) * 2012-12-14 2014-06-18 沈阳药科大学 Benzoic acid compound, and preparation method and application thereof

Also Published As

Publication number Publication date
GB2060636A (en) 1981-05-07
DE3038304C2 (en) 1985-08-08
DE3038304A1 (en) 1981-04-23
JPS5938960B2 (en) 1984-09-20
BE885631A (en) 1981-04-10
GB2060636B (en) 1984-01-11

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