JPS57140720A - Antitumor agent containing o- or m-aminobenzoic acid derivative - Google Patents

Antitumor agent containing o- or m-aminobenzoic acid derivative

Info

Publication number
JPS57140720A
JPS57140720A JP1116182A JP1116182A JPS57140720A JP S57140720 A JPS57140720 A JP S57140720A JP 1116182 A JP1116182 A JP 1116182A JP 1116182 A JP1116182 A JP 1116182A JP S57140720 A JPS57140720 A JP S57140720A
Authority
JP
Japan
Prior art keywords
aminobenzoic acid
antitumor agent
agent containing
salt
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1116182A
Other languages
Japanese (ja)
Other versions
JPS5939409B2 (en
Inventor
Chikao Yoshikumi
Fumio Hirose
Yoshio Omura
Takami Fujii
Masanori Ubusawa
Minoru Ohara
Kenichi Matsunaga
Takao Ando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Priority to JP1116182A priority Critical patent/JPS5939409B2/en
Publication of JPS57140720A publication Critical patent/JPS57140720A/en
Publication of JPS5939409B2 publication Critical patent/JPS5939409B2/en
Expired legal-status Critical Current

Links

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: A highly safe antitumor agent, containing an o- or m-aminobenzoic acid derivtive, a salt or alkyl ester thereof as an active constituent, and administrable for a long term without the danger of teratogenicity, allergic reaction, etc.
CONSTITUTION: An antitumore agent containing a compound of the formula[R1 is a saccharide residue of mono- W trisaccharides (exept arabinose, xylose, glucose, mannose and rhamnose in the monosaccharide); R1-NH- is at the o- or m-position], a salt or alkyl ester thereof as an active constituent with very low toxicity without the fear of disturbing intestinal bacterial floras due to no antimicrobial activity. The daily dose thereof is 0.1W500mg/kg for the oral administration and 0.01W200mg/kg for the parenteral administration in divided 1W4 fractions. The compound of the formula is obtained by reacting a saccharide or aminobenzoic acid or an ester thereof in a solvent in the presence or absence of a catalyst at 20W200°C.
COPYRIGHT: (C)1982,JPO&Japio
JP1116182A 1982-01-27 1982-01-27 Antitumor agents containing ortho- or meta-aminobenzoic acid derivatives Expired JPS5939409B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1116182A JPS5939409B2 (en) 1982-01-27 1982-01-27 Antitumor agents containing ortho- or meta-aminobenzoic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1116182A JPS5939409B2 (en) 1982-01-27 1982-01-27 Antitumor agents containing ortho- or meta-aminobenzoic acid derivatives

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP54162484A Division JPS6041079B2 (en) 1979-12-14 1979-12-14 Ortho- or meta-aminobenzoic acid derivatives

Publications (2)

Publication Number Publication Date
JPS57140720A true JPS57140720A (en) 1982-08-31
JPS5939409B2 JPS5939409B2 (en) 1984-09-22

Family

ID=11770308

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1116182A Expired JPS5939409B2 (en) 1982-01-27 1982-01-27 Antitumor agents containing ortho- or meta-aminobenzoic acid derivatives

Country Status (1)

Country Link
JP (1) JPS5939409B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014224318A1 (en) 2014-11-27 2016-06-02 Sms Group Gmbh Apparatus and method for cooling a roll

Also Published As

Publication number Publication date
JPS5939409B2 (en) 1984-09-22

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