JPS57140720A - Antitumor agent containing o- or m-aminobenzoic acid derivative - Google Patents
Antitumor agent containing o- or m-aminobenzoic acid derivativeInfo
- Publication number
- JPS57140720A JPS57140720A JP1116182A JP1116182A JPS57140720A JP S57140720 A JPS57140720 A JP S57140720A JP 1116182 A JP1116182 A JP 1116182A JP 1116182 A JP1116182 A JP 1116182A JP S57140720 A JPS57140720 A JP S57140720A
- Authority
- JP
- Japan
- Prior art keywords
- aminobenzoic acid
- antitumor agent
- agent containing
- salt
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: A highly safe antitumor agent, containing an o- or m-aminobenzoic acid derivtive, a salt or alkyl ester thereof as an active constituent, and administrable for a long term without the danger of teratogenicity, allergic reaction, etc.
CONSTITUTION: An antitumore agent containing a compound of the formula[R1 is a saccharide residue of mono- W trisaccharides (exept arabinose, xylose, glucose, mannose and rhamnose in the monosaccharide); R1-NH- is at the o- or m-position], a salt or alkyl ester thereof as an active constituent with very low toxicity without the fear of disturbing intestinal bacterial floras due to no antimicrobial activity. The daily dose thereof is 0.1W500mg/kg for the oral administration and 0.01W200mg/kg for the parenteral administration in divided 1W4 fractions. The compound of the formula is obtained by reacting a saccharide or aminobenzoic acid or an ester thereof in a solvent in the presence or absence of a catalyst at 20W200°C.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1116182A JPS5939409B2 (en) | 1982-01-27 | 1982-01-27 | Antitumor agents containing ortho- or meta-aminobenzoic acid derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1116182A JPS5939409B2 (en) | 1982-01-27 | 1982-01-27 | Antitumor agents containing ortho- or meta-aminobenzoic acid derivatives |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP54162484A Division JPS6041079B2 (en) | 1979-12-14 | 1979-12-14 | Ortho- or meta-aminobenzoic acid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57140720A true JPS57140720A (en) | 1982-08-31 |
JPS5939409B2 JPS5939409B2 (en) | 1984-09-22 |
Family
ID=11770308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1116182A Expired JPS5939409B2 (en) | 1982-01-27 | 1982-01-27 | Antitumor agents containing ortho- or meta-aminobenzoic acid derivatives |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5939409B2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102014224318A1 (en) | 2014-11-27 | 2016-06-02 | Sms Group Gmbh | Apparatus and method for cooling a roll |
-
1982
- 1982-01-27 JP JP1116182A patent/JPS5939409B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS5939409B2 (en) | 1984-09-22 |
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