YU2500A - Alatrofloksacin parenteralni preparati - Google Patents
Alatrofloksacin parenteralni preparatiInfo
- Publication number
- YU2500A YU2500A YU2500A YU2500A YU2500A YU 2500 A YU2500 A YU 2500A YU 2500 A YU2500 A YU 2500A YU 2500 A YU2500 A YU 2500A YU 2500 A YU2500 A YU 2500A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- alatrofloxacin
- parenteral compositions
- alatrofloxacin mesylate
- mesylate
- purifying
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
Abstract
Predmetni pronalazak se odnosi na alatrofloksacin mezilat uglavnom bez manje polarnih nečistoća, na parenteralne preparate alatrofloksacin mezilata i na postupke za prečišćavanje alatrofloksacin mezilata.[The present invention relates to alatrofloxacin mesylate substantially free of less polar impurities, to parenteral compositions of alatrofloxacin mesylate and to processes for purifying alatrofloxacin mesylate.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5424697P | 1997-08-01 | 1997-08-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU2500A true YU2500A (sh) | 2002-09-19 |
Family
ID=21989735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU2500A YU2500A (sh) | 1997-08-01 | 1998-07-23 | Alatrofloksacin parenteralni preparati |
Country Status (40)
Country | Link |
---|---|
US (1) | US6194429B1 (sh) |
EP (1) | EP1000086B1 (sh) |
JP (1) | JP3463928B2 (sh) |
KR (1) | KR20010022495A (sh) |
CN (1) | CN1265671A (sh) |
AP (1) | AP1031A (sh) |
AR (1) | AR015417A1 (sh) |
AT (1) | ATE259827T1 (sh) |
AU (1) | AU734863B2 (sh) |
BG (1) | BG104105A (sh) |
BR (1) | BR9811580A (sh) |
CA (1) | CA2296466C (sh) |
CO (1) | CO4970688A1 (sh) |
DE (1) | DE69821767T2 (sh) |
DK (1) | DK1000086T3 (sh) |
DZ (1) | DZ2576A1 (sh) |
EA (1) | EA002120B1 (sh) |
ES (1) | ES2214716T3 (sh) |
GT (1) | GT199800112A (sh) |
HN (1) | HN1998000106A (sh) |
HR (1) | HRP980417B1 (sh) |
HU (1) | HUP0004793A3 (sh) |
ID (1) | ID24374A (sh) |
IL (1) | IL134156A0 (sh) |
IS (1) | IS5339A (sh) |
MA (1) | MA24626A1 (sh) |
NO (1) | NO20000485L (sh) |
NZ (1) | NZ502249A (sh) |
OA (1) | OA11281A (sh) |
PA (1) | PA8456701A1 (sh) |
PE (1) | PE103799A1 (sh) |
PL (1) | PL338477A1 (sh) |
PT (1) | PT1000086E (sh) |
SK (1) | SK1012000A3 (sh) |
TN (1) | TNSN98146A1 (sh) |
TW (1) | TW538043B (sh) |
UY (1) | UY25113A1 (sh) |
WO (1) | WO1999006430A1 (sh) |
YU (1) | YU2500A (sh) |
ZA (1) | ZA986874B (sh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR025976A1 (es) * | 1999-10-08 | 2002-12-26 | Affinium Pharm Inc | Inhibidores de fab i. |
EP1121933A1 (en) * | 2000-02-02 | 2001-08-08 | Pfizer Products Inc. | Premixed alatrofloxacin injectable compositions |
WO2003088897A2 (en) | 2001-04-06 | 2003-10-30 | Affinium Pharmaceuticals, Inc. | Fab i inhibitors |
ES2518316T3 (es) | 2002-12-06 | 2014-11-05 | Debiopharm International Sa | Compuestos heterocíclicos, métodos de fabricación de los mismos y su uso en terapia |
EP1608377B1 (en) | 2003-03-17 | 2008-10-01 | Affinium Pharmaceuticals, Inc. | Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics |
CA2467321A1 (en) * | 2004-05-14 | 2005-11-14 | Paul J. Santerre | Polymeric coupling agents and pharmaceutically-active polymers made therefrom |
DK1828167T3 (da) * | 2004-06-04 | 2014-10-20 | Debiopharm Int Sa | Acrylamidderivater som antibiotiske midler |
WO2007067416A2 (en) * | 2005-12-05 | 2007-06-14 | Affinium Pharmaceuticals, Inc. | Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents |
JP5468899B2 (ja) | 2006-07-20 | 2014-04-09 | アフィニウム ファーマシューティカルズ, インク. | Fabiインヒビターとしてのアクリルアミド誘導体 |
EP3255045A1 (en) | 2007-02-16 | 2017-12-13 | Debiopharm International SA | Salts, prodrugs and polymorphs of fab i inhibitors |
TR201909016T4 (tr) | 2012-06-19 | 2019-07-22 | Debiopharm Int Sa | (E)-n-metil-n-((3-metilbenzofuran-2-il)metil)-3-(7-okso-5,6,7,8-tetrahidro-1,8-naftiridin-3-il)akrilamidin ön ilaç türevleri. |
BR112016024841A2 (pt) * | 2014-04-25 | 2017-10-24 | Naurex Inc | composições estáveis de peptídeos neuroativos |
AU2017223037B2 (en) | 2016-02-26 | 2022-04-14 | Debiopharm International S.A. | Medicament for treatment of diabetic foot infections |
WO2019148294A1 (en) | 2018-02-02 | 2019-08-08 | Interface Biologics, Inc. | Dimeric dexamethasone prodrug compositions and uses thereof |
CA3176134A1 (en) | 2020-05-01 | 2021-11-04 | Ripple Therapeutics Corporation | Heterodimer compositions and methods for the treatment of ocular disorders |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3713672A1 (de) | 1987-04-24 | 1988-11-17 | Bayer Ag | Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren |
US5164402A (en) * | 1989-08-16 | 1992-11-17 | Pfizer Inc | Azabicyclo quinolone and naphthyridinone carboxylic acids |
US5256791A (en) | 1992-03-02 | 1993-10-26 | Pfizer Inc. | Preparation of intermediates in the synthesis of quinoline antibiotics |
BR9408490A (pt) | 1994-01-18 | 1997-08-26 | Pfizer | Processo e intermediários para a preparação de sais do ácido nafftiridonocarboxílico |
TW420610B (en) | 1994-04-07 | 2001-02-01 | Pfizer | A pharmaceutical composition for treating a H. pylori infection or gastric or duodenal ulcers |
US5475116A (en) | 1994-04-29 | 1995-12-12 | Pfizer Inc. | Aza bicyclo[3,1,0]hexane intermediates useful in the synthesis of quinolones |
ES2117426T3 (es) | 1995-06-06 | 1998-08-01 | Pfizer | Forma cristalina de la sal anhidra compuesta de los acidos 7-((1a,5a,6a)-6-amino-3-azabiciclo(3.1.0.)hex-3-il)-6-fluoro-1-(2,4-difluorofenil)-1,4-dihidro-4-oxo-1,8-naftiridina-3-carboxilico y metanosulfonico. |
DK0833837T3 (da) * | 1995-06-15 | 2002-09-02 | Pfizer | Fremgangsmåde til fremstilling af derivater af azabicyclonaphthydridincarboxylsyre omfattende et dipeptid |
RU2151152C1 (ru) | 1995-08-29 | 2000-06-20 | Пфайзер Инк. | Полиморфы 6-n-(l-ala-l-ala)-тровафлоксацина |
KR100343909B1 (ko) | 1995-08-29 | 2003-04-10 | 화이자 인코포레이티드 | 트로바플록사신의쯔비터이온형태 |
GB9524466D0 (en) | 1995-11-30 | 1996-01-31 | Pfizer Ltd | Process |
JPH1087617A (ja) | 1996-07-09 | 1998-04-07 | Pfizer Inc | キノリン系抗生物質の合成に有用な中間体の製法 |
-
1998
- 1998-07-10 HN HN1998000106A patent/HN1998000106A/es unknown
- 1998-07-23 NZ NZ502249A patent/NZ502249A/en unknown
- 1998-07-23 DE DE1998621767 patent/DE69821767T2/de not_active Expired - Fee Related
- 1998-07-23 AT AT98932444T patent/ATE259827T1/de not_active IP Right Cessation
- 1998-07-23 US US09/403,886 patent/US6194429B1/en not_active Expired - Fee Related
- 1998-07-23 KR KR1020007001081A patent/KR20010022495A/ko not_active Application Discontinuation
- 1998-07-23 SK SK101-2000A patent/SK1012000A3/sk unknown
- 1998-07-23 PT PT98932444T patent/PT1000086E/pt unknown
- 1998-07-23 EP EP98932444A patent/EP1000086B1/en not_active Expired - Lifetime
- 1998-07-23 YU YU2500A patent/YU2500A/sh unknown
- 1998-07-23 PL PL98338477A patent/PL338477A1/xx not_active Application Discontinuation
- 1998-07-23 WO PCT/IB1998/001122 patent/WO1999006430A1/en not_active Application Discontinuation
- 1998-07-23 ES ES98932444T patent/ES2214716T3/es not_active Expired - Lifetime
- 1998-07-23 HU HU0004793A patent/HUP0004793A3/hu unknown
- 1998-07-23 CA CA002296466A patent/CA2296466C/en not_active Expired - Fee Related
- 1998-07-23 DK DK98932444T patent/DK1000086T3/da active
- 1998-07-23 IL IL13415698A patent/IL134156A0/xx unknown
- 1998-07-23 AU AU82368/98A patent/AU734863B2/en not_active Ceased
- 1998-07-23 JP JP2000505185A patent/JP3463928B2/ja not_active Expired - Fee Related
- 1998-07-23 EA EA200000086A patent/EA002120B1/ru not_active IP Right Cessation
- 1998-07-23 ID IDW20000200A patent/ID24374A/id unknown
- 1998-07-23 BR BR9811580-4A patent/BR9811580A/pt not_active Application Discontinuation
- 1998-07-23 CN CN98807829A patent/CN1265671A/zh active Pending
- 1998-07-24 PE PE1998000667A patent/PE103799A1/es not_active Application Discontinuation
- 1998-07-24 GT GT199800112A patent/GT199800112A/es unknown
- 1998-07-27 TW TW087112260A patent/TW538043B/zh not_active IP Right Cessation
- 1998-07-28 HR HR980417A patent/HRP980417B1/xx not_active IP Right Cessation
- 1998-07-28 UY UY25113A patent/UY25113A1/es unknown
- 1998-07-29 DZ DZ980186A patent/DZ2576A1/xx active
- 1998-07-30 AP APAP/P/1998/001310A patent/AP1031A/en active
- 1998-07-31 TN TNTNSN98146A patent/TNSN98146A1/fr unknown
- 1998-07-31 AR ARP980103814A patent/AR015417A1/es unknown
- 1998-07-31 CO CO98043890A patent/CO4970688A1/es unknown
- 1998-07-31 MA MA25198A patent/MA24626A1/fr unknown
- 1998-07-31 ZA ZA9806874A patent/ZA986874B/xx unknown
- 1998-08-03 PA PA19988456701A patent/PA8456701A1/es unknown
-
2000
- 2000-01-14 IS IS5339A patent/IS5339A/is unknown
- 2000-01-25 BG BG104105A patent/BG104105A/bg unknown
- 2000-01-26 OA OA1200000019A patent/OA11281A/en unknown
- 2000-01-31 NO NO20000485A patent/NO20000485L/no not_active Application Discontinuation
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