BR9811580A - Composições parentéricas de alatrofloxacina - Google Patents

Composições parentéricas de alatrofloxacina

Info

Publication number
BR9811580A
BR9811580A BR9811580-4A BR9811580A BR9811580A BR 9811580 A BR9811580 A BR 9811580A BR 9811580 A BR9811580 A BR 9811580A BR 9811580 A BR9811580 A BR 9811580A
Authority
BR
Brazil
Prior art keywords
alatrofloxacin
parenteral compositions
compositions
mesylate
parenteral
Prior art date
Application number
BR9811580-4A
Other languages
English (en)
Inventor
Robert Mark Guinn
John Francis Lambert
Subramanian Sam Guhan
Stanley Walter Walinsky
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9811580A publication Critical patent/BR9811580A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçõES PARENTéRICAS DE ALATROFLOXACINA"<D>. A presente invenção refere-se com mesilato de alatrofloxacina substancialmente isento de impurezas menos polares, as composições parentéricas de mesilato de alatrofloxacina e a processos para a purificação de mesilato de alatrofloxacina.
BR9811580-4A 1997-08-01 1998-07-23 Composições parentéricas de alatrofloxacina BR9811580A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5424697P 1997-08-01 1997-08-01
PCT/IB1998/001122 WO1999006430A1 (en) 1997-08-01 1998-07-23 Alatrofloxacin parenteral compositions

Publications (1)

Publication Number Publication Date
BR9811580A true BR9811580A (pt) 2000-08-22

Family

ID=21989735

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811580-4A BR9811580A (pt) 1997-08-01 1998-07-23 Composições parentéricas de alatrofloxacina

Country Status (40)

Country Link
US (1) US6194429B1 (pt)
EP (1) EP1000086B1 (pt)
JP (1) JP3463928B2 (pt)
KR (1) KR20010022495A (pt)
CN (1) CN1265671A (pt)
AP (1) AP1031A (pt)
AR (1) AR015417A1 (pt)
AT (1) ATE259827T1 (pt)
AU (1) AU734863B2 (pt)
BG (1) BG104105A (pt)
BR (1) BR9811580A (pt)
CA (1) CA2296466C (pt)
CO (1) CO4970688A1 (pt)
DE (1) DE69821767T2 (pt)
DK (1) DK1000086T3 (pt)
DZ (1) DZ2576A1 (pt)
EA (1) EA002120B1 (pt)
ES (1) ES2214716T3 (pt)
GT (1) GT199800112A (pt)
HN (1) HN1998000106A (pt)
HR (1) HRP980417B1 (pt)
HU (1) HUP0004793A3 (pt)
ID (1) ID24374A (pt)
IL (1) IL134156A0 (pt)
IS (1) IS5339A (pt)
MA (1) MA24626A1 (pt)
NO (1) NO20000485L (pt)
NZ (1) NZ502249A (pt)
OA (1) OA11281A (pt)
PA (1) PA8456701A1 (pt)
PE (1) PE103799A1 (pt)
PL (1) PL338477A1 (pt)
PT (1) PT1000086E (pt)
SK (1) SK1012000A3 (pt)
TN (1) TNSN98146A1 (pt)
TW (1) TW538043B (pt)
UY (1) UY25113A1 (pt)
WO (1) WO1999006430A1 (pt)
YU (1) YU2500A (pt)
ZA (1) ZA986874B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010635A1 (es) * 1999-10-08 2001-08-15 Smithkline Beecham Corp Inhibidores de fab i utiles para el tratamiento de infecciones bacterianas
EP1121933A1 (en) * 2000-02-02 2001-08-08 Pfizer Products Inc. Premixed alatrofloxacin injectable compositions
CA2444597A1 (en) 2001-04-06 2002-10-06 Affinium Pharmaceuticals, Inc. Fab i inhibitors
US7790709B2 (en) 2002-12-06 2010-09-07 Affinium Pharmaceuticals, Inc. Heterocyclic compounds, methods of making them and their use in therapy
WO2004082586A2 (en) 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
CA2467321A1 (en) * 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
EP2848614A3 (en) * 2004-06-04 2015-07-29 Debiopharm International SA Acrylamide derivatives as antibiotic agents
JP2009518399A (ja) * 2005-12-05 2009-05-07 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉ阻害剤および抗菌剤としてのヘテロ環アクリルアミド化合物
WO2008009122A1 (en) 2006-07-20 2008-01-24 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab i inhibitors
WO2008098374A1 (en) * 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
AU2013279021C1 (en) 2012-06-19 2017-03-16 Debiopharm International Sa Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
WO2015164859A1 (en) * 2014-04-25 2015-10-29 Naurex, Inc. Stable compositions of neuroactive peptides
KR20180114177A (ko) 2016-02-26 2018-10-17 데비오팜 인터네셔날 에스 에이 당뇨병성 족부 감염의 치료제
CA3087898A1 (en) 2018-02-02 2019-08-08 Ripple Therapeutics Corporation Glass formulations comprising steroid dimers and uses thereof
CN115956083A (zh) 2020-05-01 2023-04-11 波纹疗法公司 异二聚体组合物及用于治疗眼部病症的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3713672A1 (de) 1987-04-24 1988-11-17 Bayer Ag Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren
US5164402A (en) 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
US5256791A (en) 1992-03-02 1993-10-26 Pfizer Inc. Preparation of intermediates in the synthesis of quinoline antibiotics
EP0740667A1 (en) 1994-01-18 1996-11-06 Pfizer Inc. Process and intermediates for preparing naphthyridonecarboxylic acid salts
TW420610B (en) 1994-04-07 2001-02-01 Pfizer A pharmaceutical composition for treating a H. pylori infection or gastric or duodenal ulcers
US5475116A (en) 1994-04-29 1995-12-12 Pfizer Inc. Aza bicyclo[3,1,0]hexane intermediates useful in the synthesis of quinolones
US5763454A (en) 1995-06-06 1998-06-09 Pfizer, Inc. Crystal form of anhydrous 7-( 1α,5α,6α!-6-amino-3-azabicyclo 3.1.0!hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8 naphthyridine-3-carboxylic acid, methanessulfonic acid salt
US5939550A (en) * 1995-06-15 1999-08-17 Pfizer Inc. Process for preparing derivatives of azabicyclo naphthyridine carboxylic acid comprising a dipeptide
NZ312199A (en) 1995-08-29 1999-06-29 Pfizer Zwitterionic forms of trovafloxacin
KR100274736B1 (ko) * 1995-08-29 2000-12-15 디. 제이. 우드, 스피겔 알렌 제이 6-엔-(엘-에이엘에이-엘-에이엘에이)-트로바플록사신 전구약물의 폴리모프
GB9524466D0 (en) 1995-11-30 1996-01-31 Pfizer Ltd Process
JPH1087617A (ja) 1996-07-09 1998-04-07 Pfizer Inc キノリン系抗生物質の合成に有用な中間体の製法

Also Published As

Publication number Publication date
IL134156A0 (en) 2001-04-30
EA002120B1 (ru) 2001-12-24
AR015417A1 (es) 2001-05-02
AU8236898A (en) 1999-02-22
TNSN98146A1 (fr) 2005-03-15
NZ502249A (en) 2001-11-30
ID24374A (id) 2000-07-13
ZA986874B (en) 2000-01-31
JP2001512133A (ja) 2001-08-21
PL338477A1 (en) 2000-11-06
TW538043B (en) 2003-06-21
JP3463928B2 (ja) 2003-11-05
AU734863B2 (en) 2001-06-21
PT1000086E (pt) 2004-05-31
NO20000485D0 (no) 2000-01-31
DE69821767D1 (de) 2004-03-25
DE69821767T2 (de) 2005-01-13
KR20010022495A (ko) 2001-03-15
GT199800112A (es) 2000-01-15
US6194429B1 (en) 2001-02-27
HUP0004793A3 (en) 2001-10-29
HUP0004793A2 (hu) 2001-04-28
MA24626A1 (fr) 1999-04-01
AP1031A (en) 2001-12-21
HN1998000106A (es) 1999-01-08
HRP980417A2 (en) 1999-08-31
EA200000086A1 (ru) 2000-08-28
NO20000485L (no) 2000-03-27
EP1000086B1 (en) 2004-02-18
PE103799A1 (es) 1999-10-25
IS5339A (is) 2000-01-14
PA8456701A1 (es) 2000-05-24
HRP980417B1 (en) 2002-10-31
ATE259827T1 (de) 2004-03-15
UY25113A1 (es) 2000-12-29
WO1999006430A1 (en) 1999-02-11
CA2296466C (en) 2003-04-15
EP1000086A1 (en) 2000-05-17
DK1000086T3 (da) 2004-05-17
SK1012000A3 (en) 2000-09-12
CA2296466A1 (en) 1999-02-11
DZ2576A1 (fr) 2003-02-22
YU2500A (sh) 2002-09-19
CO4970688A1 (es) 2000-11-07
AP9801310A0 (en) 1998-09-30
BG104105A (bg) 2000-08-31
ES2214716T3 (es) 2004-09-16
OA11281A (en) 2002-11-19
CN1265671A (zh) 2000-09-06

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. PORTANTO, INDEFIRO O PRESENTE PEDIDO DE PATENTE COMO INVENCAO - DE ACORDO COM O ART. 8O DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.