YU14303A - Postupak pripremanja n-aril antranilnih kiselina i njihovih derivata - Google Patents
Postupak pripremanja n-aril antranilnih kiselina i njihovih derivataInfo
- Publication number
- YU14303A YU14303A YU14303A YUP14303A YU14303A YU 14303 A YU14303 A YU 14303A YU 14303 A YU14303 A YU 14303A YU P14303 A YUP14303 A YU P14303A YU 14303 A YU14303 A YU 14303A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- aryl
- derivatives
- making
- anthranilic acids
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
- C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22820600P | 2000-08-25 | 2000-08-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU14303A true YU14303A (sh) | 2006-08-17 |
Family
ID=22856235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU14303A YU14303A (sh) | 2000-08-25 | 2001-07-20 | Postupak pripremanja n-aril antranilnih kiselina i njihovih derivata |
Country Status (31)
Country | Link |
---|---|
EP (1) | EP1313694A1 (fr) |
JP (1) | JP2004507518A (fr) |
KR (1) | KR20030059115A (fr) |
CN (1) | CN1458921A (fr) |
AP (1) | AP2001002249A0 (fr) |
AR (1) | AR032175A1 (fr) |
AU (1) | AU2001277044A1 (fr) |
BG (1) | BG107635A (fr) |
BR (1) | BR0113520A (fr) |
CA (1) | CA2420003A1 (fr) |
CZ (1) | CZ2003477A3 (fr) |
DO (1) | DOP2001000238A (fr) |
EA (1) | EA200300187A1 (fr) |
GT (1) | GT200100174A (fr) |
HN (1) | HN2001000216A (fr) |
HU (1) | HUP0300828A2 (fr) |
IL (1) | IL154507A0 (fr) |
IS (1) | IS6724A (fr) |
MA (1) | MA26949A1 (fr) |
MX (1) | MXPA03001654A (fr) |
NO (1) | NO20030844L (fr) |
PA (1) | PA8526501A1 (fr) |
PE (1) | PE20020393A1 (fr) |
PL (1) | PL360699A1 (fr) |
SK (1) | SK2072003A3 (fr) |
SV (1) | SV2002000601A (fr) |
TN (1) | TNSN01127A1 (fr) |
UY (1) | UY26908A1 (fr) |
WO (1) | WO2002018319A1 (fr) |
YU (1) | YU14303A (fr) |
ZA (1) | ZA200301182B (fr) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7235537B2 (en) | 2002-03-13 | 2007-06-26 | Array Biopharma, Inc. | N3 alkylated benzimidazole derivatives as MEK inhibitors |
EP2275102B1 (fr) | 2002-03-13 | 2015-07-29 | Array Biopharma, Inc. | Dérivés de benzimidazole d'alkylat N3 en tant qu'inhibiteurs de Mek |
US7538120B2 (en) | 2003-09-03 | 2009-05-26 | Array Biopharma Inc. | Method of treating inflammatory diseases |
US7144907B2 (en) | 2003-09-03 | 2006-12-05 | Array Biopharma Inc. | Heterocyclic inhibitors of MEK and methods of use thereof |
CN100594212C (zh) | 2003-10-21 | 2010-03-17 | 沃纳-兰伯特公司 | N-[(r)-2,3-二羟基-丙氧基]-3,4-二氟-2-(2-氟-4-碘苯基氨基)-苯甲酰胺的多晶型物 |
US7517994B2 (en) | 2003-11-19 | 2009-04-14 | Array Biopharma Inc. | Heterocyclic inhibitors of MEK and methods of use thereof |
AU2004293018B2 (en) | 2003-11-19 | 2010-02-18 | Array Biopharma Inc. | Heterocyclic inhibitors of MEK and methods of use thereof |
US7732616B2 (en) | 2003-11-19 | 2010-06-08 | Array Biopharma Inc. | Dihydropyridine and dihydropyridazine derivatives as inhibitors of MEK and methods of use thereof |
RU2006121990A (ru) | 2003-11-21 | 2007-12-27 | Эррэй Биофарма Инк. (Us) | Ингибиторы протеинкиназ акт |
UA89035C2 (ru) * | 2003-12-03 | 2009-12-25 | Лео Фарма А/С | Эфиры гидроксамовых кислот и их фармацевтическое применение |
JP5154406B2 (ja) | 2005-04-13 | 2013-02-27 | アステックス、セラピューティックス、リミテッド | 医薬化合物 |
PT2361905E (pt) | 2005-05-18 | 2013-03-18 | Array Biopharma Inc | Inibidores heterocíclicos de mek e seus métodos de utilização |
US7754725B2 (en) | 2006-03-01 | 2010-07-13 | Astex Therapeutics Ltd. | Dihydroxyphenyl isoindolymethanones |
US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
CA2656566C (fr) | 2006-07-06 | 2014-06-17 | Array Biopharma Inc. | Dihydrofuro pyrimidines comme inhibiteurs de la proteine kinase akt |
JP5231411B2 (ja) | 2006-07-06 | 2013-07-10 | アレイ バイオファーマ、インコーポレイテッド | Aktプロテインキナーゼ阻害剤としてのジヒドロチエノピリミジン |
PT2049500E (pt) | 2006-07-06 | 2011-12-23 | Array Biopharma Inc | Ciclopenta[d]pirimidinas como inibidores da proteína quinase akt |
EP2081891A2 (fr) | 2006-10-12 | 2009-07-29 | Astex Therapeutics Limited | COMPOSES PHARMACEUTIQUES AYANT UNE ACTIVITE INHIBITRICE OU MODULATRICE HSP90& xA; |
WO2008044045A1 (fr) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Combinaisons pharmaceutiques |
GB0620259D0 (en) | 2006-10-12 | 2006-11-22 | Astex Therapeutics Ltd | Pharmaceutical compounds |
JP5721949B2 (ja) | 2006-10-12 | 2015-05-20 | アステックス、セラピューティックス、リミテッドAstex Therapeutics Limited | 複合薬剤 |
EP2073803B1 (fr) | 2006-10-12 | 2018-09-19 | Astex Therapeutics Limited | Combinaisons pharmaceutiques |
EP2073804B1 (fr) | 2006-10-12 | 2017-09-13 | Astex Therapeutics Limited | Composes amides d'acide benzoique substitues par un groupe hydroxyle pour son utilisation dans le traitement de la douleur |
US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
KR20150089099A (ko) | 2007-07-05 | 2015-08-04 | 어레이 바이오파마 인크. | Akt 단백질 키나제 억제제로서의 피리미딜 시클로펜탄 |
CN101918373B (zh) | 2007-07-05 | 2013-06-05 | 阵列生物制药公司 | 作为akt蛋白激酶抑制剂的嘧啶基环戊烷 |
ES2401685T3 (es) | 2008-01-09 | 2013-04-23 | Array Biopharma, Inc. | Pirimidil ciclopentano hidroxilado como inhibidor de la proteína quinasa AKT |
EP2247578B1 (fr) | 2008-01-09 | 2013-05-22 | Array Biopharma, Inc. | Pyrimidylcyclopentanes hydroxylés utilisés comme inhibiteurs de protéine kinase akt |
GB0806527D0 (en) | 2008-04-11 | 2008-05-14 | Astex Therapeutics Ltd | Pharmaceutical compounds |
CN101985428B (zh) * | 2009-07-29 | 2014-02-12 | 杭州民生药业有限公司 | 邻苯胺基苯甲酸衍生物或其药学上可接受的盐、其制备方法及其用途 |
JP2013519714A (ja) * | 2010-02-19 | 2013-05-30 | センター ナショナル デ ラ リシェルシェ サイエンティフィック | 芳香族求核置換によって目的の化学化合物を調製するための方法 |
WO2011101604A1 (fr) * | 2010-02-19 | 2011-08-25 | Centre National De La Recherche Scientifique | Procede de preparation de composes chimiques d'interet par substitution nucleophile aromatique de derives d'acides carboxyliques aromatiques portant au moins un groupement electroattracteur |
EP2694072B1 (fr) | 2011-04-01 | 2017-11-29 | Genentech, Inc. | Combinaison de composé inhibiteur d'akt et d'abiraterone pour utilisation dans des traitements thérapeutiques |
JP6147246B2 (ja) | 2011-04-01 | 2017-06-14 | ジェネンテック, インコーポレイテッド | Akt及びmek阻害剤化合物の組み合わせ、及び使用方法 |
GEP201706690B (en) * | 2012-10-12 | 2017-06-26 | Exelixis Inc | Novel process for making compounds for use in treatment of cancer |
CN112745237B (zh) * | 2019-10-29 | 2023-06-20 | 中国科学院上海药物研究所 | 2-芳基胺类化合物及其制备方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3138636A (en) * | 1960-06-23 | 1964-06-23 | Parke Davis & Co | Anthranilic acid derivatives |
US6251943B1 (en) * | 1997-02-28 | 2001-06-26 | Warner-Lambert Company | Method of treating or preventing septic shock by administering a MEK inhibitor |
DE69826662T2 (de) * | 1997-07-01 | 2005-02-17 | Warner-Lambert Co. Llc | 4-brom or 4-iod-phenylamino-benzhydroxamsäurederivate und ihre anwendung als mek-inhibitoren |
NZ501277A (en) * | 1997-07-01 | 2002-12-20 | Warner Lambert Co | -2(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors |
CA2348236A1 (fr) * | 1999-01-13 | 2000-07-20 | Stephen Douglas Barrett | 4-arylamino, 4-aryloxy, et 4-arylthio diarylamines et leurs derives comme inhibiteurs selectifs de mek |
PT1171418E (pt) * | 1999-04-21 | 2005-02-28 | Warner Lambert Co | Metodo de preparacao de acidos 2-(n-fenilamino)benzoicos |
-
2001
- 2001-07-20 PL PL36069901A patent/PL360699A1/xx unknown
- 2001-07-20 CA CA002420003A patent/CA2420003A1/fr not_active Abandoned
- 2001-07-20 CN CN01815869A patent/CN1458921A/zh active Pending
- 2001-07-20 EP EP01954824A patent/EP1313694A1/fr not_active Withdrawn
- 2001-07-20 AP APAP/P/2001/002249A patent/AP2001002249A0/en unknown
- 2001-07-20 CZ CZ2003477A patent/CZ2003477A3/cs unknown
- 2001-07-20 EA EA200300187A patent/EA200300187A1/ru unknown
- 2001-07-20 HU HU0300828A patent/HUP0300828A2/hu unknown
- 2001-07-20 AU AU2001277044A patent/AU2001277044A1/en not_active Abandoned
- 2001-07-20 JP JP2002523437A patent/JP2004507518A/ja active Pending
- 2001-07-20 BR BR0113520-1A patent/BR0113520A/pt not_active Application Discontinuation
- 2001-07-20 KR KR10-2003-7002675A patent/KR20030059115A/ko not_active Application Discontinuation
- 2001-07-20 WO PCT/US2001/022948 patent/WO2002018319A1/fr not_active Application Discontinuation
- 2001-07-20 YU YU14303A patent/YU14303A/sh unknown
- 2001-07-20 SK SK207-2003A patent/SK2072003A3/sk unknown
- 2001-07-20 MX MXPA03001654A patent/MXPA03001654A/es unknown
- 2001-07-20 IL IL15450701A patent/IL154507A0/xx unknown
- 2001-08-15 SV SV2001000601A patent/SV2002000601A/es not_active Application Discontinuation
- 2001-08-22 TN TNTNSN01127A patent/TNSN01127A1/en unknown
- 2001-08-23 PA PA20018526501A patent/PA8526501A1/es unknown
- 2001-08-24 UY UY26908A patent/UY26908A1/es not_active Application Discontinuation
- 2001-08-24 AR ARP010104047A patent/AR032175A1/es unknown
- 2001-08-24 GT GT200100174A patent/GT200100174A/es unknown
- 2001-08-24 DO DO2001000238A patent/DOP2001000238A/es unknown
- 2001-08-24 PE PE2001000853A patent/PE20020393A1/es not_active Application Discontinuation
- 2001-09-26 HN HN2001000216A patent/HN2001000216A/es unknown
-
2003
- 2003-02-12 ZA ZA200301182A patent/ZA200301182B/en unknown
- 2003-02-20 IS IS6724A patent/IS6724A/is unknown
- 2003-02-24 NO NO20030844A patent/NO20030844L/no not_active Application Discontinuation
- 2003-03-13 BG BG107635A patent/BG107635A/bg unknown
- 2003-03-14 MA MA27069A patent/MA26949A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
PL360699A1 (en) | 2004-09-20 |
PE20020393A1 (es) | 2002-05-09 |
CN1458921A (zh) | 2003-11-26 |
IS6724A (is) | 2003-02-20 |
CZ2003477A3 (cs) | 2003-10-15 |
KR20030059115A (ko) | 2003-07-07 |
JP2004507518A (ja) | 2004-03-11 |
IL154507A0 (en) | 2003-09-17 |
CA2420003A1 (fr) | 2002-03-07 |
SK2072003A3 (en) | 2004-01-08 |
SV2002000601A (es) | 2002-04-03 |
NO20030844L (no) | 2003-02-25 |
GT200100174A (es) | 2002-07-18 |
EP1313694A1 (fr) | 2003-05-28 |
WO2002018319A1 (fr) | 2002-03-07 |
NO20030844D0 (no) | 2003-02-24 |
AU2001277044A1 (en) | 2002-03-13 |
AR032175A1 (es) | 2003-10-29 |
TNSN01127A1 (en) | 2005-11-10 |
ZA200301182B (en) | 2004-05-12 |
EA200300187A1 (ru) | 2003-08-28 |
AP2001002249A0 (en) | 2001-09-30 |
MA26949A1 (fr) | 2004-12-20 |
BR0113520A (pt) | 2003-06-24 |
DOP2001000238A (es) | 2003-01-31 |
HUP0300828A2 (hu) | 2003-09-29 |
PA8526501A1 (es) | 2002-07-30 |
UY26908A1 (es) | 2001-11-30 |
HN2001000216A (es) | 2002-05-22 |
BG107635A (bg) | 2004-09-30 |
MXPA03001654A (es) | 2004-09-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP2001002249A0 (en) | Process for making N-ARYL-ANTHRANILIC acids and their derivatives. | |
PL350453A1 (en) | N−cyanomethyl amides as protease inhibitors | |
BR0013885A (pt) | Comprimidos aperfeiçoados | |
HUP0004123A3 (en) | Carboxylic acid amide derivatives, process for their preparation and pharmaceutical compositions containing them | |
TNSN01108A1 (en) | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | |
HU0101336D0 (en) | Process for the preparation of perindopril and their pharmaceutically acceptable salts | |
AU8830801A (en) | Use of derivatives of valproic acid amides and 2-valproenic acid amides for the treatment or prevention of pain and/or headache disorders | |
IL117091A0 (en) | Methylphenyloxazolidinone derivatives pharmaceutical compositions containing the same and processes for the preparation thereof | |
MX9705726A (es) | Amidas del acido alcoximinoacetico. | |
GB0306346D0 (en) | Process for the preparation of gabapentin | |
UA35607C2 (uk) | Похідні оксазолідинонкарбонової кислоти, спосіб їх одержання, фармацевтична композиція і спосіб її одержання | |
BG104243A (en) | Method for the synthesis of quinoline derivatives | |
MXPA03008837A (es) | Una composicion farmaceutica estable de pravastatina. | |
PL346015A1 (en) | Methoximinophenylacetic acid amides | |
MXPA03002047A (es) | Fenilciclohexanocarboxamidas substituidas y su uso. | |
AU2002234066A1 (en) | Process for the production of amides | |
IL146257A0 (en) | Method of producing methoxyimido acetic amide | |
AU2002240828A1 (en) | Process for the preparation of alpha-aminosubstituted carboxylic acid amides | |
DE50010009D1 (en) | Hydroxamsäurederivate | |
JO2258B1 (en) | Method for preparing hydroxamic acids | |
HUP9903371A3 (en) | Carboxylic acid derivatives, their production and use of them for producing pharmaceutical compositions |