WO2021140741A1 - 自動分析装置、自動分析装置の表示システム、および自動分析装置における表示方法 - Google Patents

自動分析装置、自動分析装置の表示システム、および自動分析装置における表示方法 Download PDF

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Publication number
WO2021140741A1
WO2021140741A1 PCT/JP2020/042016 JP2020042016W WO2021140741A1 WO 2021140741 A1 WO2021140741 A1 WO 2021140741A1 JP 2020042016 W JP2020042016 W JP 2020042016W WO 2021140741 A1 WO2021140741 A1 WO 2021140741A1
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WIPO (PCT)
Prior art keywords
screen
information
analysis
display
automatic analyzer
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Ceased
Application number
PCT/JP2020/042016
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English (en)
French (fr)
Japanese (ja)
Inventor
和彰 柴
聖 横塚
正志 圷
真章 近久
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Hitachi High Tech Corp
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Hitachi High Tech Corp
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Priority to EP20911316.6A priority Critical patent/EP4089417A4/en
Priority to CN202080090831.6A priority patent/CN114902053A/zh
Priority to JP2021569739A priority patent/JP7329625B2/ja
Priority to US17/789,834 priority patent/US20230056397A1/en
Publication of WO2021140741A1 publication Critical patent/WO2021140741A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00871Communications between instruments or with remote terminals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00594Quality control, including calibration or testing of components of the analyser
    • G01N35/00613Quality control
    • G01N35/00623Quality control of instruments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00326Analysers with modular structure
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N2035/00891Displaying information to the operator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002Reagent dispensers

Definitions

  • the present invention relates to an automatic analyzer that performs quantification and qualitative analysis of biological samples (hereinafter referred to as samples or samples) such as blood, plasma, serum, urine, and other body fluids, a display system of the automatic analyzer, and an automatic analyzer. Regarding the display method.
  • Patent Document 1 states that the apparatus body has an arrangement of a sample insertion unit, an analysis unit, and the like. A rail is laid along the direction, and a display device is movably mounted on the rail, and a plurality of position detection sensors for detecting the current position of the display device are arranged on the rail. The detection position information indicating the current position of the display device detected by any of the position detection sensors is supplied to the control device, and in the control device, the current position of the sample or reagent in the device body according to the current position of the display device is provided. It is stated that a status information screen showing the status is created and supplied to the display device.
  • Automatic analyzers that automatically perform quantitative and qualitative analysis of samples such as blood and urine are used in many medical institutions, mainly hospitals and clinical laboratory centers, where many patient samples need to be processed in a short time. There is.
  • control unit operates each mechanism in the device according to the user's instructions during analysis of the items requested by the user and the specified settings in the operation unit. It is playing an active part in making it.
  • the display unit which is one of the operation units, allows you to set request items during analysis, parameter settings during maintenance, etc., as well as modules that are difficult to visually understand, such as the remaining amount of reagents and the progress of maintenance.
  • the status is displayed and visualized. Therefore, the user can perform operations and operations necessary for analysis while grasping the state of the device through this display unit.
  • the user can operate while alternately observing the display information of the display unit and the operation of the device at the time of setting or analysis. At this time, the user can change the display contents by operating the check boxes and combo boxes on the screen of the display unit.
  • Patent Document 1 states that the current position of the display unit detected by the position detection sensor or the current position of the user is displayed by the control unit. The configuration for changing the status information screen displayed on the unit is explained.
  • the processing capacity and the like are improved by integrating a plurality of analysis modules into one module as a group of devices including one analysis device and a device that executes a pre-analysis operation of the analysis device.
  • the connected analysis modules are not limited to the same type, and the types are becoming more and more popular.
  • a biochemical analysis module for measuring cholesterol in blood and an immunoassay module for measuring infectious diseases there is also a device in which a plurality of different or similar analysis modules are connected.
  • the flow has changed from measuring only a large number of samples to measuring various items.
  • the present invention provides an automatic analyzer, a display system for the automatic analyzer, and a display method for the automatic analyzer, which can provide a screen according to the situation of the automatic analyzer more accurately and reliably to the user as compared with the conventional case. provide.
  • the present invention includes a plurality of means for solving the above problems. For example, at least two or more analysis modules for analyzing a sample, a display unit for displaying information on the analysis modules, and a display unit for displaying the information of the analysis modules.
  • the analysis module and a control unit that controls the operation of the display unit are provided, and the control unit includes at least one of the position information of the display unit, the angle information of the display unit, and the operation information for the analysis module.
  • a first screen in which information on at least two analysis modules is displayed and a second screen in which information on only a specific analysis module among the analysis modules is displayed are displayed separately. And.
  • FIG. 1 It is a top view which shows the outline of the whole structure of the automatic analyzer which concerns on Example 1 of this invention. It is a front view which shows the outline of the whole structure of the automatic analyzer which concerns on Example 1.
  • FIG. It is a figure explaining the outline of the 1st screen on the reagent information display screen of the automatic analyzer which concerns on Example 1.
  • FIG. It is a figure explaining the outline of the 2nd screen concerning the analysis module 207 in the automatic analysis apparatus which concerns on Example 1.
  • FIG. It is a figure explaining the outline of the 2nd screen concerning the analysis module 107 in the automatic analysis apparatus which concerns on Example 1.
  • FIG. 1st screen On the maintenance screen of the sample dispensing nozzle of the automatic analyzer which concerns on Example 1.
  • FIG. It is a figure explaining the outline of the 1st screen of the state monitor screen of the sample dispensing nozzle of the automatic analyzer which concerns on Example 1.
  • FIG. It is a figure explaining the outline of the 2nd screen concerning the maintenance of the sample dispensing nozzle of the analysis module 207 in the automatic analyzer which concerns on Example 1.
  • FIG. 2nd screen concerning the maintenance of the sample dispensing nozzle of the analysis module 107 in the automatic analyzer which concerns on Example 1.
  • FIG. It is a figure explaining the outline of the analysis setting screen in the automatic analysis apparatus which concerns on Example 1.
  • FIG. 1 It is a figure explaining the outline of the screen transition setting screen in the automatic analyzer which concerns on Example 1.
  • FIG. It is a figure explaining the outline of the screen transition setting screen in the automatic analyzer which concerns on Example 1.
  • FIG. It is a flowchart which shows the flow from the screen start-up in the automatic analyzer which concerns on Example 1 to the display of the 1st screen or the 2nd screen.
  • Example 1 The automatic analyzer of the present invention, the display system of the automatic analyzer, and the first embodiment of the display method in the automatic analyzer will be described with reference to FIGS. 1 to 14.
  • FIGS. 1 and 2 are views showing the overall configuration of the automatic analyzer according to the present embodiment, and shows an outline when viewed from the upper part in FIG. 1 and from the front in FIG.
  • the automatic analyzer 100 of this embodiment shown as an example in FIG. 1 accommodates a plurality of analysis modules 107 and 207 (two in this embodiment) and samples to be analyzed by these analysis modules 107 and 207. It is roughly composed of a sampler module 200 for transporting a sample rack on which one or more sample containers are mounted, and a control device 300 for controlling the overall operation of the automatic analyzer 100.
  • the sample rack is loaded with one or more sample containers containing the samples to be subjected to qualitative / quantitative analysis in the analysis modules 107 and 207.
  • the sample rack includes at least a sample rack (hereinafter, simply referred to as a sample rack 101) on which a sample container containing a sample (normal sample) to be analyzed with a normal priority is mounted, and the sample rack 101.
  • a sample rack hereinafter, referred to as an emergency sample rack 101A when distinguished from the sample rack 101
  • a sample rack hereinafter, referred to as an emergency sample rack 101A when distinguished from the sample rack 101
  • the sampler module 200 is a module for transporting the sample rack 101 loaded into the automatic analyzer 100 between the analysis modules 107 and 207, and includes a sample rack supply unit 102, an emergency sample rack loading unit 112, a transport line 104, and an emergency.
  • a sample rack standby area 113, a sample identification device 105, a rack rotor 106, a sample rack storage unit 103, and the like are provided.
  • the transport line 104 is, for example, a belt conveyor type transport mechanism that reciprocates the sample rack 101 and the emergency sample rack 101A.
  • the emergency sample rack loading section 112 is provided adjacent to the transport line 104 and is an area for loading the emergency sample rack 101A.
  • the sample rack supply unit 102 is provided adjacent to the transfer line 104 on one end side of the transfer line 104 with respect to the emergency sample rack loading unit 112, and is an area for supplying the sample rack 101 of a normal sample.
  • the sample rack storage unit 103 is provided adjacent to the transport line 104 on one end side of the transport line 104 with respect to the sample rack supply unit 102, and is an area for storing the sample rack 101.
  • the emergency sample rack standby area 113 is provided on the transfer line 104 on the other end side of the transfer line 104 from the sample rack storage unit 103, and is an area for temporarily waiting the emergency sample rack 101A.
  • the sample identification device 105 refers to the sample rack 101 and the RFID or bar provided on the sample container in order to inquire the analysis request information regarding the sample contained in the sample container mounted on the sample rack 101 transported on the transport line 104. It is a mechanism for reading and identifying an identification medium (not shown) such as a code.
  • the rack rotor 106 is arranged at one end of the transport line 104.
  • the rack rotor 106 has one or more slots 106a and 106b on which the sample rack 101 and the like can be mounted, and one end of the transport line 104 and one end of the dispensing lines 109 and 209 of the analysis modules 107 and 207, respectively. It is a mechanism for exchanging and receiving the sample rack 101 and the like with and from.
  • the rack rotor 106 has a structure that rotates clockwise and counterclockwise, so that processing is started in the order in which the sample rack 101 is loaded, or the sample rack 101 having a high priority is loaded.
  • the rotation operation is appropriately controlled so that the processing can be started before the sample rack 101 put in earlier.
  • the analysis modules 107 and 207 are units that perform qualitative and quantitative analysis by sampling (dispensing) the samples contained in the sample container mounted on the sample rack 101, and the dispensing lines 109 and 209, respectively. , Specimen identification device 110, 210, reaction disc 118, 218, sample dispensing mechanism 108, 208, reagent disc 119, 219, reagent dispensing mechanism 120, 220, measuring unit (not shown), and the like.
  • the dispensing lines 109 and 209 are reciprocating transferable transport mechanisms that pull the sample rack 101 from the sampler module 200 to the analysis modules 107 and 207 and deliver the sample rack 101 from the analysis modules 107 and 207 to the sampler module 200. Is adopted. For example, it is a belt conveyor type mechanism.
  • a protrusion structure driven along the dispensing lines 109 and 209 is provided in advance in the sample rack 101. It is possible to adopt a configuration in which the portion is fitted into the recess and conveyed. Such a configuration is the same for the transport line 104.
  • the sample identification devices 110 and 210 are provided adjacent to the other end side of the dispensing lines 109 and 209, and analysis request information for the sample stored in the sample rack 101 carried into the dispensing lines 109 and 209. This is a mechanism for reading and identifying identification media (not shown) such as RFID and barcodes provided on the sample rack 101 and the sample container in order to collate.
  • the sample dispensing mechanism 108, 208 is a mechanism for dispensing a sample from the sample container of the sample rack 101 conveyed to the dispensing position on the dispensing lines 109, 209 to the reaction container of the reaction disks 118, 218.
  • the reagent dispensing mechanisms 120 and 220 are mechanisms for dispensing the reagents contained in the reagent containers of the reagent disks 119 and 219 into the reaction vessels of the reaction disks 118 and 218.
  • the measuring unit is a mechanism that performs qualitative and quantitative analysis by measuring the mixed solution (reaction solution) of the sample and reagent dispensed into the reaction vessel.
  • the analysis module 107 is assumed to be a unit for biochemical examination, and the analysis module 207 is assumed to be a unit for immunological examination. In this case, the purpose and processing capacity of the examination are different.
  • a measurement unit for measuring the electrolyte concentration can be provided in the analysis module 107, or a measurement unit for blood coagulation analysis or the like can be appropriately arranged in each module according to the specification environment.
  • multiple analysis modules can be configured to maintain the same processing capacity with the same analysis module, and if only the purpose is different, multiple different analysis modules can be connected. It can be configured to be.
  • the control device 300 is a device that controls the entire operation of the automatic analysis device 100 including the devices of the analysis modules 107 and 207 and the sampler module 200, and is a computer equipped with a CPU, a memory, and the like.
  • the control device 300 includes a display unit 116, an input device 117, a storage unit 115, a control unit 114, and the like.
  • the display unit 116 displays information such as input screens for various parameters and settings, analytical inspection data for initial inspection or re-inspection, measurement results, and information related to maintenance of the analysis modules 107 and 207 and the sampler module 200. It is a display device such as a liquid crystal display that displays various types of information. It should be noted that it may be composed of a touch panel type display device that also serves as an input device 117, which will be described later.
  • the display unit 116 since the display unit 116 is located in the center of the automatic analyzer 100, the display unit 116 is configured to be rotatable toward the immunoassay module 207 side or the biochemical analysis module 107 side. .. Then, when it is tilted toward the immunoassay module 207 by a predetermined angle or more, it corresponds to the immunoassay module 207, and when it is tilted toward the biochemical analysis module 107 by a predetermined angle or more, it corresponds to the biochemical analysis module 107.
  • the predetermined angle is set to 30 °.
  • the display unit 116 of the present embodiment when the lower direction in FIG. 1 is set as the reference angle, which direction the display unit 116 is rotated in, the analysis module 107 or the analysis module 207, is rotated.
  • An angle detector 121 for detecting an angle is provided.
  • the input device 117 is composed of a keyboard and a mouse for inputting various data such as various parameters and settings, analysis request information, and instructions for starting analysis.
  • the storage unit 115 is a semiconductor memory such as a flash memory that records the measurement result of the sample put into the automatic analyzer 100 and the analysis request information of the sample stored in the sample container mounted on each sample rack. It is a recording medium such as a magnetic disk such as an HDD. The storage unit 115 also records various parameters and set values for controlling the operation of each device in the automatic analyzer 100, various computer programs for executing various processes described later, and the like.
  • the control unit 114 is a part that controls the entire operation of the automatic analysis device 100 including the control device 300, the analysis modules 107 and 207, and the sampler module 200, and is the above-mentioned CPU and the like.
  • control unit 114 is the first screen on which the information of the analysis modules 107 and 207 is displayed based on the angle information of the display unit 116 detected by the angle detector 121.
  • the second screen on which the information of only the specific analysis modules 107 and 207 is displayed is displayed separately.
  • the remaining amount of the reagent required for analysis, the expiration date of the reagent, and the reagent information of at least one of the target modules using the reagent are displayed.
  • the maintenance information including the maintenance progress status of the analysis modules 107 and 207 is displayed on the first screen, and the maintenance progress of the specific analysis modules 107 and 207 is displayed on the second screen. Display maintenance information including the status.
  • control unit 114 causes the display unit 116 to display a setting screen for selecting a screen for displaying and separating the first screen and the second screen and a screen for not sorting.
  • the above is the general configuration of the automatic analyzer 100.
  • the sample analysis process by the automatic analyzer 100 as described above is generally executed in the following order.
  • the operator gives an analysis instruction to the automatic analyzer 100 using the display unit 116 and the input device 117.
  • the analysis instruction is stored in the storage unit 115 and transmitted to the target analysis module among the sampler module 200 and the analysis modules 107 and 207 via the control device 300.
  • the target module performs the analysis operation as follows according to the received analysis instruction.
  • the sampler module 200 sends the sample racks 101 installed in the sample rack supply unit 102 one by one onto the transport line 104 and carries them into the rack rotor 106.
  • the sample rack 101 transported to the rack rotor 106 is transported to the dispensing line 109 of the analysis module 107 or the dispensing line 209 of the analysis module 207 according to the measurement items requested by the control device 300.
  • the sample dispensing mechanism 108 and 208 performs a dispensing operation for each sample mounted on the sample rack 101.
  • the sample dispensing mechanism 108 discharges the sucked sample into the reaction vessel on the reaction disk 118. Then, the reagent sucked from the reagent disk 119 by the reagent dispensing mechanism 120 is further added to the reaction vessel, and the mixture is stirred. After that, the absorbance and the like are measured by the measuring unit, and the measurement result is transmitted to the control unit 114 of the control device 300.
  • the reaction vessel used for the analysis is washed with water, alkaline detergent, and acidic detergent dispensed from the washing mechanism (not shown) and used for the next analysis.
  • the reagent sucked from the reagent disk 219 by the reagent dispensing mechanism 220 is discharged into the reaction vessel on the reaction disk 218, and the sample dispensing mechanism 208 is used for the reaction vessel. Add more sample and stir. Then, after performing processing such as magnetic separation as necessary, the measurement is performed by the measuring unit, and the measurement result is transmitted to the control unit 114 of the control device 300.
  • the control unit 114 obtains the concentration of a specific component in the sample from the transmitted measurement result by arithmetic processing, displays the result on the display unit 116 or the like, or stores the result in the storage unit 115.
  • the display unit 116 is installed on the upper surface of the sampler module 200.
  • a top cover 141 is installed on the upper part of the biochemical analysis module 107
  • a top cover 241 is installed on the upper part of the immunoassay module 207.
  • the top covers 141 and 241 can be opened and closed, and the top view of the top cover in the opened state is shown in FIG.
  • open / close detectors 142 and 242 for detecting the opening of the top covers 141 and 241 are installed in the apparatus.
  • FIG. 3 is a diagram for explaining the outline of the first screen on the reagent information display screen
  • FIG. 4 is a diagram for explaining the outline of the second screen for the analysis module 207
  • FIG. 5 is a diagram for explaining the outline of the second screen for the analysis module 107. It is a figure to do.
  • the reagent information display screen as shown in FIGS. 3 to 5 is displayed by pressing the reagent button (not shown) from the displayed global menu after logging in to the system.
  • the reagent information display screen 400 of FIG. 3 is a screen for displaying information on reagents mounted on the analysis modules 107 and 207, and corresponds to the first screen.
  • the names 402, the remaining amount 403, and the target module names 404 of all the reagents currently registered are displayed as a reagent list on the left side of the screen.
  • the user opens the reagent information display screen 400 to check the remaining amount and expiration date of the registered reagent, register the reagent, and the like.
  • the top covers 141 and 241 of the analysis modules 107 and 207 corresponding to the reagent are opened, the reagent is mounted, and the reagent registration button 415 in FIG. 3 is pressed to press the system. Register the reagent above.
  • the display range when the reagent information display screen 400 is started is for all analysis modules, and the reagent information of both the immunoassay module 207 and the biochemical analysis module 107 is displayed on the screen.
  • the reagent information of the non-target module is unnecessary, and if the non-target reagent information is displayed, it may lead to an erroneous operation. There is sex.
  • combo box 405 as a method of switching the display range for each analysis module.
  • all modules "biochemical analysis module”
  • the reagent information display screen with the display unit 116 facing the front. 400 was opened, the combo box 405 was selected using the input device 117, and the information related to the target analysis module was selected as the display range. Then, after moving to the front of the target analysis module and exchanging the insufficient reagent, the input device 117 was operated again and the reagent was registered from the reagent registration button 415.
  • control unit 114 is in a state where the display unit 116 is facing the front (for example, when the detection angle by the angle detector 121 is 0 °), as shown in FIG.
  • the control unit 114 executes the control of displaying the information related to both the immunoassay module 207 and the biochemical analysis module 107 as the first screen, the time and effort for the user to move and press the combo box 405 is saved.
  • FIG. 4 when the user instructs to display the reagent information display screen while the display unit 116 is rotated 30 ° or more toward the immunoassay module 207 as shown by the rotation operation 501, or the reagent information is already displayed.
  • the control unit 114 displays only the reagent information corresponding to the immunoassay module 207 as shown in FIG.
  • the reagent information display screen 500 is displayed on the display unit 116.
  • the reagent information display screen 500 shown in FIG. 4 does not display the reagent information related to the biochemical analysis module 107, and only the reagent information related to the immunoassay module 207 is displayed. ..
  • the reagent information display screen 500 corresponds to the second screen.
  • the combo box 505 automatically switches to the contents of the immunoassay module 207, and the module reagent name 502, the remaining amount 503, and the target module name 504 also contain only information about the immunoassay module 207. Is displayed.
  • FIG. 5 when the user gives an instruction to display the reagent information display screen in a state where the display unit 116 is rotated 30 ° or more toward the biochemical analysis module 107 as shown by the rotation operation 601 or already.
  • the control unit 114 displays the reagent information corresponding to the biochemical analysis module 107 as shown in FIG.
  • the reagent information display screen 600 in which only is displayed is displayed on the display unit 116.
  • the combo box 605 automatically shows the contents of the biochemical analysis module 107 with the rotation, and the module reagent name 602, the remaining amount 603, and the target module name 604 are also related to the biochemical analysis module 107. Only information is displayed.
  • FIG. 6 is a diagram for explaining the outline of the maintenance screen
  • FIG. 7 is a diagram for explaining the outline of the first screen on the maintenance screen of the sample dispensing nozzle
  • FIG. 8 is a diagram for explaining the outline of the first screen of the sample dispensing nozzle status monitor screen.
  • FIG. 9 is a diagram for explaining the outline
  • FIG. 9 is a diagram for explaining the outline of the second screen regarding the maintenance of the sample dispensing nozzle of the analysis module 207
  • FIG. 10 is a diagram explaining the outline of the second screen regarding the maintenance of the sample dispensing nozzle of the analysis module 107. It is a figure explaining.
  • the maintenance item display screen 700 shown in FIG. 6 is a screen displayed by pressing the maintenance button 701 located in the global area after logging in to the system.
  • FIG. 6 from the list 702 showing the types of maintenance, maintenance items corresponding to one maintenance type focused by being selected by using the input device 117 are displayed in Table 704.
  • Table 704. In the case of FIG. 6, since the check maintenance 703 is in focus, the items corresponding to the maintenance are displayed in Table 704.
  • Table 704 displays module information 705 and 707, device information 706, name 708, and last implementation date and time 709 that are the targets of each maintenance item.
  • module information 705 and 707 and the device information 706, ⁇ is described in the module column to be the target of each maintenance item for each column.
  • the sample dispensing confirmation maintenance 710 the biochemical analysis module 107 and the immunoassay module 207 are used, and the control device 300 is not used.
  • the final implementation date and time 709 is updated every time maintenance is performed. To carry out maintenance, click the sample dispensing confirmation maintenance 710 with the input device 117 and press the menu button 711 that appears by focusing on it, and select the pop-up menu 712 to go to each maintenance execution screen. Transition.
  • the sample dispensing confirmation maintenance implementation screen 800 in FIG. 7 is a screen for setting and implementing the sample dispensing confirmation maintenance implementation.
  • Sample dispensing confirmation maintenance can be set for each analysis module.
  • the check box 801 corresponding to the control device 300 is displayed as an inactive state because maintenance is not performed.
  • the check box 802 corresponding to the immunoassay module 207 and the check box 803 corresponding to the biochemical analysis module 107 are in an active state because maintenance can be performed.
  • Settings for the immunoassay module 207 include a combo box 804 for the amount of dispensing, a combo box 805 for the type of plug, and a box 806 for specifying the number of dispensings.
  • a combo box 807 for the dispensing amount there are a combo box 808 for the type of plug, and a box 809 for specifying the number of dispensings.
  • the combo boxes 804,805,807,808 can be set using the combo box, and the designated boxes 806 and 809 can be set using the text box.
  • the combo boxes 804 and 805 and the designated box 806 are inactive when the check box 802 is off, and the combo boxes 807 and 808 and the designated box 809 are inactive when the check box 803 is off.
  • the sample dispensing confirmation maintenance is performed by pressing the execution button 810.
  • sample dispensing confirmation maintenance is an interactive maintenance, and when the execution button 810 is pressed on the display unit 116, the state monitor screen 900 as shown in FIG. 8 is displayed, and an instruction from the system is given. Is displayed.
  • column 902 is a detailed state 904 indicating the progress during maintenance of the immunoassay module 207, a specific instruction sentence 905, and an instruction confirmation button 906, and column 903 is a column 903 during maintenance of the biochemical analysis module 107.
  • a detailed state 907 indicating the progress status, a specific instruction sentence 908, and an instruction confirmation button 909.
  • the maintenance item display screen 700 shown in FIG. 6, the sample dispensing confirmation maintenance execution screen 800 shown in FIG. 7, and the state monitor screen 900 shown in FIG. 8 correspond to the first screen, as shown in each of the drawings. , Information relating to both the immunoassay module 207 and the biochemical analysis module 107 is displayed together.
  • the pop-up menu 712 is selected by the user while the display unit 116 is rotated to the immunoassay module 207 side by 30 ° or more, or when the sample dispensing confirmation maintenance execution screen 800 is already displayed.
  • the display unit 116 is rotated to the immunoassay module 207 side by 30 ° or more, as shown in FIGS. 9 and 10, the user does not remove the check box of the non-target analysis module, and FIG.
  • the sample dispensing maintenance execution screen 1000 on which only the maintenance information corresponding to the immunoassay module 207 as shown in the above is displayed is displayed on the display unit 116 as the second screen.
  • the check box 1002 corresponding to the immunoanalysis module 207 is turned on, the combo boxes 1004 and 1005 and the designated box 1006 are also activated, and the user changes the settings. Is possible.
  • the check box 1003 reflecting the biochemical analysis module 107 is turned off, and the combo boxes 1007, 1008 and the designated box 1009 are also inactive. Therefore, the setting related to the biochemical analysis module 107 is not possible.
  • the maintenance execution button 1010 When the maintenance execution button 1010 is pressed in the state shown in FIG. 9, maintenance is performed only on the immunoassay module 207, and the transition to the state monitor screen as shown in FIG. 8 is performed. In this case, the immunoassay module 207 is displayed. Only the maintenance state of is activated, and the detailed state 907, the instruction sentence 908, and the instruction confirmation button 909 for the biochemical analysis module 107 are not displayed, and the display is the same as that of the control module column in FIG.
  • the control unit 114 displays only the maintenance information corresponding to the biochemical analysis module 107 as shown in FIG. 10. Sample dispensing maintenance The implementation screen 1100 is displayed on the display unit 116 as the second screen.
  • sample dispensing maintenance execution screen 1100 unlike the sample dispensing maintenance implementation screen 1000 shown in FIG. 9, the check box 1103 corresponding to the biochemical analysis module 107 is turned on, the combo boxes 1107, 1108, and the designated boxes 1109. Is also activated, and the user can change the settings.
  • the check box 1102 corresponding to the immunoassay module 207 is in the off state, and the combo boxes 1104 and 1105 and the designated box 1106 are also inactive, so that the setting related to the immunoassay module 207 is not possible.
  • the screen in which the transition control between the first screen and the second screen described in this embodiment is suitable and the screen in which the transition control is not suitable are suitable.
  • Examples of the screen to which the screen switching control described in this embodiment is suitable include the reagent information display screen described in FIGS. 3 to 5 and the maintenance screen described in FIGS. 7 to 10. On these screens, the user can operate the screen at the same time as operating the hardware, and the user can save the trouble of going back and forth between the display unit 116 and the target analysis module.
  • FIG. 11 is a diagram illustrating an outline of the analysis setting screen.
  • the analysis setting screen 1200 shown in FIG. 11 is a screen for setting the execution of liquid level detection and bubble detection of reagents during analysis. Since the timing of operating the analysis setting screen 1200 is before the start of analysis, in most cases, the user is located only in front of the display unit 116 even when the analysis is performed in a specific analysis module unit.
  • the settings during analysis can be easily changed, leading to incorrect settings in the analysis.
  • the user is located in front of the display unit 116, and it is very unlikely that the display unit 116 is tilted or moved from that state.
  • transition control between the first screen and the second screen is not preferably applied to the screen for system setting such as the analysis setting screen 1200.
  • the effect of transition control between the first screen and the second screen is particularly effective for screens such as reagent-related screens and maintenance-related screens, where the user is expected to be located in front of a specific analysis module. It can be said that it is effective.
  • FIG. 12 is a diagram for explaining the outline of the screen transition setting screen
  • FIG. 13 is a diagram for explaining the outline of the screen transition setting screen.
  • lists 1301 and 1401 show major items in which the screens are roughly divided into items, for example, system screens and application screens. Etc., a total of 13 major items are displayed. When one of the items is clicked, it is focused and the list 1303, 1403 of the screen of the focused item is displayed.
  • the focus can be applied by clicking the detailed setting item from the screen list, and the menu buttons 1304 and 1404 and the screen transition setting buttons 1305 and 1405 are displayed.
  • the screen transition setting buttons 1305 and 1405 columns 1306 and 1406 are checked, and the screen of the item is a screen to which the transition control between the first screen and the second screen is applied. It is also possible to sort only the checked columns 1306 and 1406.
  • the menu button 1304 is pressed and the screen transition setting button 1305 is pressed to check the location corresponding to the barcode reading setting screen in column 1306. Is attached, and the transition control between the first screen and the second screen is applied to the barcode reading setting screen.
  • the menu button 1404 is pressed and the screen transition setting button 1405 is pressed, so that the barcode reading setting screen of column 1406 is pressed.
  • the corresponding part is checked, and the transition control between the first screen and the second screen is applied to the reagent detail screen.
  • FIG. 14 is a flowchart showing a flow from screen startup to displaying the first screen or the second screen.
  • the screen to be adapted is displayed, or is started from the time when it is already displayed (step S301).
  • Each of the following steps shall be performed at specific time intervals during the operation of the device.
  • the angle information of the display unit 116 is acquired by the angle detector 121 (step S302).
  • control unit 114 determines whether or not the display unit 116 is tilted to either the biochemical analysis module 107 side or the immunoassay module 207 side by 30 ° or more (step S303). When it is determined that none of the modules is tilted by 30 ° or more, the process proceeds to step S304, and the first screen, which is all module information, is displayed on the display unit 116 (step S304).
  • step S303 when it is determined in step S303 that the display unit 116 is tilted to any module side by 30 ° or more, the control unit 114 determines whether the display unit 116 is tilted to the biochemical analysis module 107 side by 30 ° or more. (Step S305).
  • the control unit 114 indicates information about the biochemical analysis module 107.
  • the second screen is displayed (step S307).
  • Section 114 displays a second screen showing information about the immunoassay module 207 (step S306).
  • the automatic analyzer 100 of the first embodiment of the present invention described above includes two or more analysis modules 107 and 207 for analyzing a sample, a display unit 116 for displaying information of the analysis modules 107 and 207, and an analysis module 107.
  • a first screen comprising a control unit 114 that controls the operation of the display unit 116 and the display unit 116, and the control unit 114 displays information on at least two analysis modules 107 and 207 based on the angle information of the display unit 116.
  • the second screen in which the information of only the specific analysis modules 107 and 207 is displayed among the analysis modules 107 and 207 are displayed separately.
  • the display range can be switched from a specific module target to a plurality of module targets depending on the situation, and the display range is related to a specific module. It is possible to instantly confirm the configuration from the information to the information related to the entire device.
  • an automatic analyzer in which a plurality of types of analysis modules are integrated, it is suitable for an automatic analyzer that shares a display unit that displays information related to analysis corresponding to each analysis module.
  • an angle detector 121 for detecting the angle of the display unit 116 is further provided, and the control unit 114 displays the first screen and the second screen separately based on the angle information detected by the angle detector 121. Since it is only necessary to tilt the display unit 116 by a predetermined angle or more, the second screen for displaying information about a specific module and the first screen for displaying the entire information are switched without performing complicated screen transition operations.
  • the user works on a specific module without taking the trouble of moving from the front of the target module, less important information is not described, it is easy for the user to understand, and malfunction can be prevented.
  • the first screen is displayed only by turning the display unit 116 to the front, so the act of manually selecting the display range from the combo box described above can be omitted, so the user The burden on the module can be significantly reduced.
  • control unit 114 causes the display unit 116 to display a setting screen for selecting a screen for displaying the first screen and the second screen and a screen for not sorting, so that the user can optionally display the first screen and the second screen. It is possible to set a screen that transitions to the screen, and it is possible to turn off the screen transition setting for screens for which transition control is not suitable, such as the analysis setting screen, and the operation of the device. Can increase the stability of.
  • control unit 114 displays the maintenance information including the maintenance progress status of the analysis modules 107 and 207 on the first screen, and displays the maintenance information including the maintenance progress status of the specific analysis modules 107 and 207 on the second screen. Display it.
  • the user When performing maintenance for a specific analysis module, for example, when performing sample dispensing confirmation maintenance, installing racks on the dispensing lines 109 and 209 of each module, the user operates the target analysis module. It must be located in front of the target analysis module.
  • the information of the immunoassay module 207 is to be known while using the biochemical analysis module 107, the information of the immunoassay module 207 can be easily obtained by turning the display unit 116 to the front. The effect of is also obtained.
  • control unit 114 causes the user to display the remaining amount of the reagent required for the analysis, the expiration date of the reagent, and the reagent information of at least one of the target modules using the reagent on the first screen and the second screen.
  • the information required for accessing a specific analysis module can be displayed on the large screen and the second screen, and the user's work can be assisted more effectively.
  • the mode in which the control unit 114 executes the transition control based on the angle information of the display unit 116 has been described, but it is not limited to the angle information of the display unit 116 and is based on the position information of the display unit 116.
  • the first screen on which the information of the two analysis modules 107 and 207 is displayed and the second screen on which the information of only the specific analysis modules 107 and 207 of the analysis modules 107 and 207 are displayed can be displayed separately.
  • FIG. 15 is a diagram illustrating a method of performing a transition to the second screen of the analysis module 207 in the automatic analyzer according to the second embodiment
  • FIG. 16 is a diagram illustrating a method of performing a transition to the second screen of the analysis module 107. It is a figure.
  • the display unit 116 is configured to be rotatable or, in addition, to be translateable to the analysis modules 107 and 207.
  • the configuration that enables parallel movement may be a known configuration, and for example, a rail or the like can be used.
  • a position detector 122 for detecting the position of the display unit 116 is provided, and the control unit 114 is the first screen based on the position information detected by the position detector 122. And the second screen are displayed separately.
  • the display unit 116 when the display unit 116 was moved to the upper part of the immunoassay module 207 as shown in FIG. 15, it was moved to the upper part of the biochemical analysis module 107 so as to correspond to the immunoassay module 207. In some cases, it corresponds to the biochemical analysis module 107.
  • the display unit 116 when the display unit 116 is located at the upper part of the sampler module 200, the information related to all the modules is displayed as the first screen, and when it is moved to the upper part of the immunoanalysis module 207, the immunoanalysis is performed as the second screen. Only the information related to the module 207 is displayed, and when it is moved to the upper part of the biochemical analysis module 107, only the information related to the biochemical analysis module 107 is displayed.
  • the control unit 114 specifies the first screen on which the information of the two analysis modules 107 and 207 is displayed and the analysis modules 107 and 207 based on the position information of the display unit 116.
  • the second screen in which the information of only the analysis modules 107 and 207 of the above is displayed is displayed separately.
  • the position detector 122 for detecting the position of the display unit 116 is further provided, and the control unit 114 is provided by the position detector 122.
  • the information of the two analysis modules 107 and 207 is displayed based on the information of the operation of the analysis modules 107 and 207 by the user, instead of the information about the display unit 116 as in the above-described first and second embodiments.
  • the first screen and the second screen in which the information of only specific analysis modules 107 and 207 among the analysis modules 107 and 207 are displayed are displayed separately.
  • the analysis modules 107 and 207 are a protection unit and an analysis unit that protect the analysis unit that analyzes the sample and the analysis unit such as the top covers 141 and 241 that cover the upper part of the analysis modules 107 and 207.
  • it has an operation detection unit that detects that a predetermined operation has been performed on the protection unit.
  • Examples of the operation detection unit include open / close detectors 142 and 242 for detecting the opening of the top covers 141 and 241 as shown in FIG. 2.
  • the control unit 114 is the analysis module 107, respectively.
  • the opening / closing of the top covers 141,241 of 207 is associated with the reagent information display screens 400, 500, 600 shown in FIG. The first screen and the second screen are displayed and separated.
  • Reagent exchange is carried out by opening the top covers 141 and 241 of the analysis modules 107 and 207, which are the targets of the reagents to be exchanged, when the module state is standby.
  • the user opens the reagent information display screen and operates the reagent registration button 415 to register the exchanged reagent.
  • the top covers 141 and 241 are opened, and the reagent information display screen is displayed in this state. That is, if the reagent information display screen is displayed at the same time as the top covers 141 and 241 are opened, the user does not have to manually display the reagent information display screen. Further, since the displayed reagent information display screen is the screen of the corresponding analysis module, it is not necessary for the user to set the display range using the combo box as in the first embodiment.
  • the reagent information display screen 600 shown in FIG. 5 is displayed, and the top of the immunoassay module 207 is displayed.
  • the cover 141 is opened, the reagent information display screen 500 shown in FIG. 4 is displayed.
  • top covers 141 and 241 of both the biochemical analysis module 107 and the immunoassay module 207 are opened within a predetermined time, or when one top cover is opened and the other top cover is also opened. In this case, it is desirable to display the reagent information display screen 400, which is the first screen.
  • the timing at which the screen transition control based on the opening and closing of the top covers 141 and 241 is preferably applied is that the replacement work is completed unless it takes more time than necessary to replace the reagent. It is assumed that the time is within a predetermined time from the moment when the top covers 141 and 241 are opened. Therefore, when the predetermined time has passed, the first screen can be displayed even when the top covers 141 and 241 are continuously opened.
  • the screen display It is not necessary to associate the screen display with the detection information that the top covers 141 and 241 are closed, but when it is detected that the top covers 141 and 241 are closed, the first screen is displayed as in the case where a predetermined time has elapsed. It can also be displayed.
  • the control unit 114 displays the first screen and the second screen separately based on the states of the analysis modules 107 and 207 in addition to the opening / closing information detected by the opening / closing detectors 142 and 242. It shall be.
  • the module state indicates the state related to the entire device, and multiple states such as standby in normal time and operation during analysis are defined. Then, in the predetermined module state, when the user performs a predetermined operation on the analysis module, a specific screen can be displayed.
  • the control unit 114 displays the information of the two analysis modules 107 and 207 on the first screen and the analysis modules 107 and 207 based on the operation information of the analysis modules 107 and 207.
  • the second screen in which information on only specific analysis modules 107 and 207 is displayed is displayed separately.
  • the analysis modules 107 and 207 protect the analysis unit and the analysis unit that analyze the sample.
  • An operation detection unit that detects that a predetermined operation has been performed on the unit, the analysis unit, or the protection unit, for example, the analysis modules 107 and 207 is a top cover 1411 that covers the upper part of the analysis modules 107 and 207 as a protection unit.
  • control unit 114 displays the first screen and the second screen separately based on the states of the analysis modules 107 and 207 in addition to the operation information detected by the operation detection unit, thereby improving the convenience of the user. Can be improved.
  • the opening / closing information of the top covers 141 and 241 is associated with the reagent information display screen has been described, but the user also operates the reaction disk 118, the reagent disk 119, the reagent dispensing mechanism 120, and the like. At that time, the screen corresponding to any mechanism can be displayed.
  • the transition control between the first screen and the second screen of Examples 1 to 3 described above is not limited to the case where it is executed by the control unit 114 in the control device 300 in the automatic analyzer 100, and the automatic analysis is performed.
  • LIS Laboratory Information System
  • HIS Hospital Information System: hospital information system
  • LIS and HIS function as a display system such as an automatic analyzer, and the first screen display signal displaying the information of the two analysis modules 107 and 207 and the specific analysis module of the analysis modules 107 and 207.
  • the second screen display signal that displays information only for 107 and 207, the position information of the display unit 116 that displays the information of the analysis modules 107 and 207, the angle information of the display unit 116, and the operation information for the analysis modules 107 and 207. It will be output to the display unit 116 separately based on at least one of the information.

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PCT/JP2020/042016 2020-01-07 2020-11-11 自動分析装置、自動分析装置の表示システム、および自動分析装置における表示方法 Ceased WO2021140741A1 (ja)

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EP20911316.6A EP4089417A4 (en) 2020-01-07 2020-11-11 Automatic analysis device, display system of automatic analysis device, and method for carrying out display in automatic analysis device
CN202080090831.6A CN114902053A (zh) 2020-01-07 2020-11-11 自动分析装置、自动分析装置的显示系统以及自动分析装置的显示方法
JP2021569739A JP7329625B2 (ja) 2020-01-07 2020-11-11 自動分析装置、自動分析装置の表示システム、および自動分析装置における表示方法
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JPWO2021140741A1 (https=) 2021-07-15

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