WO2020095425A1 - Produit cosmétique - Google Patents

Produit cosmétique Download PDF

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Publication number
WO2020095425A1
WO2020095425A1 PCT/JP2018/041592 JP2018041592W WO2020095425A1 WO 2020095425 A1 WO2020095425 A1 WO 2020095425A1 JP 2018041592 W JP2018041592 W JP 2018041592W WO 2020095425 A1 WO2020095425 A1 WO 2020095425A1
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WIPO (PCT)
Prior art keywords
acid
extract
inulin
oil
added
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PCT/JP2018/041592
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English (en)
Japanese (ja)
Inventor
和弘 岩▲崎▼
洋子 仁木
明宏 橋本
祐貴 勝間田
幸浩 大橋
和田　正
典久 石田
健二郎 原
豪彦 松山
Original Assignee
日本精化株式会社
フジ日本精糖株式会社
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Application filed by 日本精化株式会社, フジ日本精糖株式会社 filed Critical 日本精化株式会社
Priority to PCT/JP2018/041592 priority Critical patent/WO2020095425A1/fr
Priority to CN201880099362.7A priority patent/CN113015515B/zh
Publication of WO2020095425A1 publication Critical patent/WO2020095425A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/12—Face or body powders for grooming, adorning or absorbing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/06—Preparations for styling the hair, e.g. by temporary shaping or colouring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners

Definitions

  • the present invention relates to cosmetics.
  • Inulin is a type of polysaccharide that is widely distributed in nature and is present in the form of colloids on the tubers and roots of chicory roots of the Asteraceae plants such as dahlia, Jerusalem artichoke and Oguruma. Its structure is D-fructose dehydrated and polymerized by ⁇ - (2 ⁇ 1) bond on the fructose side of sucrose. It is known that such plant-derived inulin has a degree of polymerization distribution in the range of about 8 to 60 and an average degree of polymerization of about 30 although there are some differences depending on the type of plant. There is.
  • a method for producing inulin a method of extracting from the plant as described above is known and is also used industrially. Further, higher plants capable of extracting inulin as described above naturally include an enzyme that produces inulin, and an enzyme obtained by extracting from such a plant is used to produce inulin. Although a method is known, it is not practical to use it on an industrial scale because it requires a considerable amount of time and labor to prepare a large amount of enzyme from a plant. As another method, there is known a method of producing an inulin analogue by using a microbial enzyme.
  • the compounds produced by using the enzymes of these microorganisms mainly have a structure in which fructose is dehydrated and polymerized by a ⁇ - (2 ⁇ 1) bond like inulin, but its properties are different from those of plant-derived inulin. It is called inulin-type polyfructan in distinction from inulin because it is very different (the molecule is huge or the binding mode is different).
  • Patent Documents 1 and 2 As a new method for producing inulin using a microbial enzyme, a method using an enzyme derived from a microorganism belonging to the genus Bacillus has been developed (Patent Documents 1 and 2). According to this method, it is possible to obtain an inulin composition having the same structure as plant-derived inulin and a similar average molecular weight. In addition, the average degree of polymerization can be controlled by adjusting the synthesis conditions, and inulin having a narrow degree of polymerization distribution can be obtained. Inulin obtained by such a method has been mainly tried to be used in foods (for example, Patent Documents 3 and 4, Non-Patent Document 1).
  • Patent Document 5 discloses a skin cosmetic containing inulin, and it is described that it is useful as a moisturizer with no stickiness and a good familiarity.
  • the inulin used in this document was obtained by using conidia of Aspergillus sydowii, and its molecular weight is described as 10,000 to 10,000,000.
  • Patent Documents 6 and 7 describe that inulin or a derivative thereof has various physiological activities on skin cells.
  • the inulin used in these documents is of plant origin, and its average degree of polymerization is described as 5 to 30.
  • Patent Document 8 describes that inulin is useful as a conditioning agent for rinse-off cosmetics and as a substitute for a cationic polymer.
  • the inulin used in this document is derived from chicory and has a degree of polymerization of 2 to 70 and an average degree of polymerization of 10 to 12. That is, application of inulin derived from plants and inulin-type polyfructans derived from conventionally known microbial enzymes to cosmetics is already known. However, inulin-type polyfructans derived from these plant-derived inulins and microbial enzymes have insufficient solubility in water for use in cosmetics, which causes problems such as precipitation and turbidity in the formulation. There was also, and the usability was not always satisfactory.
  • an object of the present invention is to provide a cosmetic having high solubility in water, excellent stability during formulation, and excellent usability.
  • the present inventors have found that the average degree of polymerization of all inulin is 13 to 23, and 95% by weight of inulin having a degree of polymerization of 5 to 29 is contained in 100% by weight of total inulin. It has been found that by using the inulin composition containing the above, it is possible to provide a cosmetic having high solubility in water, excellent stability during formulation, and excellent feeling in use. The present inventors have conducted further research based on such findings and completed the present invention.
  • the present invention provides the following cosmetics.
  • Item 1. The average degree of polymerization of all inulins is 13-23, A cosmetic comprising an inulin composition containing 95% by mass or more of inulin having a degree of polymerization of 5 to 29 in 100% by mass of total inulin.
  • Item 2. Item 2. The cosmetic according to Item 1, further containing a water-soluble polysaccharide.
  • Item 3. The cosmetic according to Item 2, wherein the water-soluble polysaccharide is one or more selected from the group consisting of a white jellyfish polysaccharide, hyaluronic acid, and xanthan gum.
  • Item 4. Item 4. The cosmetic according to any one of Items 1 to 3, which is a skin cleanser.
  • the cosmetic composition of the present invention it is possible to provide a cosmetic composition having high solubility in water, excellent stability during formulation, and excellent feeling in use.
  • the cosmetic of the present invention has an average degree of polymerization of all inulin of 13 to 23, and comprises an inulin composition containing 95% by weight or more of inulin having a degree of polymerization of 5 to 29 in 100% by weight of total inulin. To do.
  • the inulin composition used in the present invention has a controlled average degree of polymerization and is characterized by a narrow distribution of the degree of polymerization.
  • the inulin composition used in the present invention has an average degree of polymerization of all inulins contained in the inulin composition of 13 to 23, and a degree of polymerization of 5 to 5 in 100% by weight of total inulin. It contains 95% by mass or more of 29 inulins.
  • the analysis of the average degree of polymerization of the obtained inulin can be performed as follows.
  • the degree of polymerization is the number of saccharide units (fructose and glucose units) in inulin, and the average degree of polymerization is determined by a usual analytical method such as HPLC, GC, HPAEC, etc. as follows.
  • the top of the peaks of each analysis result is the average degree of polymerization.
  • ULTRON PS-80N 8 ⁇ 300 mm
  • Shinwa Kako solvent; water, flow rate: 0.5 ml / min, temperature: 50 ° C.
  • TSK-GEL G30000 PWXL (7.8) manufactured by TOSOH.
  • the average degree of polymerization of the inulin composition is less than 13, the effect of imparting a dry feeling is not sufficient, and the effect of improving foam quality is not sufficiently exerted. On the contrary, if the average degree of polymerization is larger than 23, the solubility in water becomes poor and the sticky feeling becomes strong, which is not preferable.
  • the inulin composition contained in the cosmetic of the present invention contains 95% by mass or more of inulin having a degree of polymerization of 5 to 29 in 100% by mass of total inulin.
  • the distribution of the degree of polymerization becomes wide, many of those having a small degree of polymerization and those having a large degree of polymerization outside the range of the degree of polymerization of the present invention are included.
  • the degree of polymerization is small, the effect of imparting a dry feeling is not sufficient, and the effect of improving the foam quality is not sufficiently exerted.On the other hand, if the degree of polymerization is large, the solubility in water becomes poor and the stickiness becomes sticky. It is not preferable because the feeling becomes strong.
  • Such an inulin composition can be produced using, for example, an enzyme derived from a microorganism belonging to the genus Bacillus. Specifically, it is as described in Patent Documents 1 and 2, but the gist thereof is as described below.
  • the inulin synthase will be described. From an enzyme derived from a microorganism belonging to the genus Bacillus, more specifically, from a culture solution or culture of Bacillus sp. 217C-11 strain (FERMBP-7450) or a treated product thereof. What is obtained can be used. The method for culturing the Bacillus sp. 217C-11 strain and the method for preparing the enzyme will be briefly described below.
  • the carbon source added to the medium may be one normally used at an appropriate concentration.
  • saccharides such as sucrose, glucose, fructose and maltose can be used alone or in combination, and the most preferable carbon source is sucrose.
  • the enzyme activity is improved by culturing in a liquid medium using this as a main carbon source.
  • the nitrogen source in addition to organic nitrogen sources such as peptone, meat extract, yeast extract, corn steep liquor, sulfuric acid, nitric acid, inorganic nitrogen sources such as ammonium salts of phosphoric acid can be used alone or in combination. ..
  • inorganic salts potassium, sodium, calcium, magnesium, manganese, iron, and other sulfates, hydrochlorides, carbonates, nitrates, phosphates and the like can be used alone or in combination. Further, if necessary, nutritional sources such as amino acids and vitamins used in ordinary culture can be appropriately used. As a specific medium, sucrose is 0.5 to 2% (w / v), peptone is 1%, yeast extract is 0.5%, dipotassium phosphate is 0.2%, and the pH is 7 to 7. Eight liquid media can be used.
  • Culturing can be performed with shaking or using a jar fermenter under aerated conditions.
  • the pH of the medium is preferably in the range of 6 to 9
  • the culturing temperature is preferably in the range of 25 to 37 ° C.
  • the culturing time is 5 to 96 hours, preferably 15 to 96 hours, as long as the microorganism can grow. 72 hours.
  • the cells were sterilized by centrifugation, and then the culture supernatant was concentrated using an ultrafiltration membrane with a molecular weight cut off of 30,000 for reaction. Can be used as the enzyme solution.
  • 217C-11 strain has the following physicochemical properties. Molecular weight: 45,000-50,000 Optimum temperature: 40-50 ° C Thermal stability: gradually deactivates above 45 ° C, 70% at 50 ° C, Shows 40% residual activity at 60 ° C Optimal pH: 7-8 (45 ° C) pH stability: Stable above pH 6
  • this inulin synthase has an action and substrate specificity that acts on sucrose to produce inulin but does not act on kestose, maltose, lactose, trehalose, and cellobiose.
  • the concentration of inulin synthase may be such that sucrose (substrate) in the reaction solution can be sufficiently utilized.
  • sucrose when sucrose is 40 to 60% (w / w), the activity of inulin synthase is 0.
  • the concentration is preferably such that the reaction solution is 4 units / mL.
  • Appropriate conditions for producing inulin using sucrose as a substrate are preferably a reaction solution having a pH in the range of 6 to 8.
  • a phosphate buffer solution may be used to maintain the pH of the reaction solution.
  • the reaction time may be appropriately changed depending on the amount of inulin synthase used and the like, but is usually 0.1 to 100 hours, preferably 0.5 to 72 hours.
  • the sucrose concentration In the production of the inulin composition, (1) adjustment of the sucrose concentration, (2) adjustment of the temperature when the inulin synthase is brought into contact with sucrose, and (3) the average degree of polymerization of inulin produced by additional addition of sucrose. It can be adjusted.
  • sucrose concentration is carried out according to the average degree of polymerization of inulin produced when inulin is synthesized by bringing inulin synthase into contact with sucrose.
  • the specific sucrose concentration is, for example, in the range of 3 to 68% (w / w), preferably 10 to 60% (w / w), but by setting the sucrose concentration to be low within the above range,
  • the average degree of polymerization of the obtained inulin can be increased. For example, when the reaction temperature is 15 ° C, the average degree of polymerization of inulin obtained when the sucrose concentration of the raw material is 50% is 10, whereas the average degree of polymerization of inulin obtained when the sucrose concentration of the raw material is 20%.
  • the degree of polymerization is 18.
  • the reaction temperature is 37 ° C
  • the average degree of polymerization of inulin obtained when the sucrose concentration of the raw material is 60% is 9
  • the average degree of polymerization of inulin obtained when the sucrose concentration of the raw material is 20%.
  • the degree of polymerization is 20. Therefore, by appropriately setting the sucrose concentration, inulin having a desired average degree of polymerization can be obtained.
  • the inulin produced in the reaction solution can be purified according to a known method. For example, it can be carried out by purifying the obtained reaction solution with an ion exchange resin, activated carbon or the like, concentrating it under reduced pressure or concentrating with a reverse osmosis membrane, and then cooling to obtain inulin crystals. Alternatively, it is possible to precipitate and collect inulin by adding an organic solvent such as ethanol to the reaction solution, but not limited thereto.
  • the content of the inulin composition in the cosmetic is not particularly limited as long as it does not impair the effects of the present invention, and is usually 0.01 to 30% by mass, preferably 0.05 to 15% by mass. ..
  • a cosmetic containing the inulin composition of the present invention further contains a water-soluble polysaccharide.
  • a water-soluble polysaccharide specifically, white jellyfish polysaccharides, hyaluronic acid, xanthan gum, alginic acid, guar gum, cationized guar gum, carrageenan, gellan gum, agarose, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, cellulose nanofibers and the like.
  • Glycyrrhiza polysaccharide, hyaluronic acid, and xanthan gum are most preferable.
  • the amount of the water-soluble polysaccharide is not particularly limited as long as it does not impair the effects of the present invention, from the viewpoint of sufficiently exerting the effect of the combined use of the inulin composition and the water-soluble polysaccharide, The amount is usually 0.001 to 2 times by mass, preferably 0.002 to 1 times by mass, and most preferably 0.005 to 0.5 times by mass.
  • each may be mixed in a cosmetic, or a premix composition prepared by dissolving the inulin composition and the water-soluble polysaccharide in water is prepared. You may mix
  • the cosmetics of the present invention include, if necessary, water and additive components usually added to cosmetics, such as oily bases, surfactants, alcohols, humectants, polymers, thickening / gelling agents, and oxidizing agents.
  • moisturizing agents / feel-improving agents include glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, Trimethylolpropane, pentaerythritol, hexylene glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, polyols such as ethylene glycol / propylene glycol copolymers and their polymers; diethylene glycol monoethyl ether.
  • Alcohols glucose, fructose, galactose, mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose, raffinose, gluconic acid, glucuronic acid, cyclodextrins ( ⁇ -, ⁇ -, ⁇ - Cyclodextrin and modified cyclodextrins such as maltosylated and hydroxyalkylated), ⁇ -glucan, chitin, chitosan, heparin and derivatives, pectin, and arabi Sugars such as nogalactan, dextrin, dextran, glycogen, ethyl glucoside, glucosyl ethyl methacrylate polymer or copolymer, and derivatives thereof; hyaluronic acid, sodium hyaluronate; sodium chondroitin sulfate
  • Palmitoyl oligopeptides palmitoyl pentapeptides, palmitoyl tetrapeptides and other acylated peptides; silylated peptides; lactic acid bacteria culture fluid, yeast extract, eggshell membrane proteins, bovine submaxillary mucin, hypotaurine, sesame lignan glycosides , Glutathione, Albumin, Whey; Choline chloride, Phosphorylcholine; Placenta extract, Elastin, Collagen, Aloe extract, Hamamelis water, Luffa water, Chamomile extract, Licorice extract, Comfrey extract, Silk extract, Pleurotus cornucopia extract, Yarrow extract , Eucalyptus extract, melilot extract and other animal / plant extract components, natural ceramide (types 1, 2, 3, 4, 5, 6), hydroxyceramide, pseudoceramide, glycosphingolipid, ceramide and sugar-ceramide-containing extract Ceramides
  • the surfactant include anionic surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants and polymer surfactants.
  • the HLB of the surfactant is not particularly limited, and it is possible to use a low HLB of about 1 to a high HLB of about 20, and it is also preferable to combine a low HLB and a high HLB.
  • the surfactant include anionic surfactants such as fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfate salts such as sodium lauryl sulfate, triethanolamine lauryl sulfate and ammonium lauryl sulfate; laureth Polyoxyethylene alkyl sulfates such as sodium sulfate and laureth sulfate triethanolamine; cocoyl methyl taurine sodium, cocoyl methyl taurine potassium, lauroyl methyl taurine sodium, myristoyl methyl taurine sodium, lauroyl methyl alanine sodium, lauroyl sarcosine sodium, lauroyl sarcosine triethanol Amines, acyl N-methyl amino acid salts such as sodium methylalanine lauroylglutamate; cocoylglu Acyl amino acid salts such as sodium minate, cocoyl glutamate triethanolamine, sodium lauroyl glutamate, sodium
  • Alkyltrimethylammonium chloride such as cetrimonium chloride and lauryltrimonium chloride; Alkyltrimethylammonium bromide such as stearyltrimonium bromide; Dialkyldimethylammonium chloride such as distearyldimonium chloride and dicocodimonium chloride; Stearamidopropyldimethylamine Fatty acid amidoamines such as stearamidoethyldiethylamine and salts thereof; alkyl ether amines such as stearoxypropyldimethylamine and Or quaternary salts of fatty acid amide-type quaternary ammonium salts such as ethyl sulfate long-chain branched fatty acid (12 to 31) aminopropylethyldimethylammonium, lanolin fatty acid aminopropylethyldimethylammonium ethylsulfate; polyoxyethylene alkylamines and the like Salts or
  • Dimethylamino acid betaine fatty acid amide alkyl-N, N-dimethylamino acid betaine such as cocamidopropyl betaine and lauramidopropyl betaine; imidazoline betaine such as sodium cocoamphoacetate and sodium lauroamphoacetate; alkylsulfobetaine such as alkyldimethyltaurine; alkyl Sulfate type betaines such as dimethylaminoethanol sulfate ester; Phosphate type betaines such as alkyldimethylaminoethanol phosphate ester; phosphatidylcholine, phosphatidylethanolamine , Phosphatidylserine, sphingolipids such as sphingomyelin, lysolecithin, hydrogenated soybean phospholipids, partially hydrogenated soybean phospholipids, hydrogenated egg yolk phospholipids, partially hydrogenated egg yolk phospholipids, phospholipids such as hydroxylated lec
  • Polymers / thickeners / gelling agents include guar gum, locust bean gum, queens seed, carrageenan, galactan, gum arabic, tara gum, tamarind, furceleran, karaya gum, trolooi, cara gum, tragacanth gum, pectin, pectic acid and sodium.
  • Salts such as salts, salts such as alginic acid and sodium salts, mannan; starches such as rice, corn, potato, wheat; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salts, xanthan gum, pullulan, gellan gum, chitin , Chitosan, agar, Cassius extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypro Cellulose, carboxymethyl cellulose and salts thereof such as sodium, methyl hydroxypropyl cellulose, sodium cellulose sulfate, cellulose dialkyl dimethyl ammonium sulfate, crystalline cellulose, cellulose powder and other derivatives thereof; soluble starch, carboxymethyl starch, methyl hydroxypropyl starch , Starch starch polymers such as methyl starch, starch derivatives such as hydroxyprop
  • acrylic acid / methyl acrylate / methacrylamidopropyl trimethylammonium chloride copolymer methacrylic acid methacrylic acid choline ester polymer; cationized oligosaccharide, cationized dextran, cationized polysaccharide such as guar hydroxypropyltrimonium chloride Polyethyleneimine; Cationic polymer; Polymer of 2-methacryloyloxyethylphosphorylcholine such as polyquaternium-51 and copolymer with butyl methacrylate copolymer; Acrylic resin emulsion, polyacrylic acid ethyl emulsion, polyacrylic alkyl ester emulsion Polymer emulsions such as polyvinyl acetate resin emulsion, natural rubber latex and synthetic latex; nitrocellulose; polyurethanes and various copolymers; various silicones Silicone-based copolymers such as acrylic-silicone graft copolymers
  • Solvents / propellants include lower alcohols such as ethanol, 2-propanol (isopropyl alcohol), butanol and isobutyl alcohol; glycols such as propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol and isopentyl diol.
  • lower alcohols such as ethanol, 2-propanol (isopropyl alcohol), butanol and isobutyl alcohol
  • glycols such as propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol and isopentyl diol.
  • diethylene glycol monoethyl ether ethoxydiglycol
  • ethylene glycol monoethyl ether ethylene glycol monobutyl ether
  • triethylene glycol monoethyl ether diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, dipropylene glycol monoethyl ether
  • Glycol ethers such as ethylene glycol monoethyl ether
  • Glycol ether esters such as diacetate, diethylene glycol monoethyl ether acetate, propylene glycol monoethyl ether acetate
  • glycol esters such as diethoxyethyl succinate, ethylene glycol disuccinate
  • tocopherol vitamin E
  • tocopherol acetate and other tocopherol derivatives BHT, BHA
  • gallic acid derivatives such as propyl gallate
  • vitamin C ascorbic acid
  • erythorbic acid and its derivatives Preferred are sulfites such as sodium sulfite; hydrogen sulfites such as sodium hydrogen sulfite; thiosulfates such as sodium thiosulfate; metabisulfite; thiotaurine, hypotaurine; thioglycerol, thiourea, thioglycolic acid, and cysteine hydrochloride.
  • the reducing agent include thioglycolic acid, cysteine, cysteamine, and the like.
  • Preferred oxidizing agents include hydrogen peroxide solution, ammonium persulfate, sodium bromate, and percarbonate.
  • Antibacterial agents or preservatives include parabens (hydroxybenzoic acid esters) such as methylparaben, ethylparaben, propylparaben and butylparaben; phenoxyethanol; 1,2-pentanediol, 1,2-hexanediol, 1,2-octane.
  • parabens hydroxybenzoic acid esters
  • methylparaben ethylparaben
  • propylparaben and butylparaben phenoxyethanol
  • 1,2-pentanediol 1,2-hexanediol
  • 1,2-octane 1,2-octane
  • 1,2-alkanediols such as diols; alkylglyceryl ethers such as 2-ethylhexylglyceryl ether (ethylhexylglycerin); salicylic acid; sodium benzoate; isothiazolinone derivatives such as methylchloroisothiazolinone and methylisothiazolinone; imidazo Dehydroacetic acid and its salts; Phenols; Halogenated bisphenols such as triclosan, acid amides, quaternary ammonium salts; Trichlorocarbanide, zinc pyrithione, vinyl chloride Zarconium, benzethonium chloride, sorbic acid, chlorhexidine, chlorhexidine gluconate, halocarbane, hexachlorophene, hinokitiol; other phenols such as phenol, isopropylphenol, cresol, thymol, parachlorophenol,
  • chelating agent examples include edetates such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na (ethylenediaminetetraacetate); hydroxyethylethylenediaminetriacetate such as HEDTA3Na; pentetate (diethylenetriaminepentaacetate); phytic acid; etidronate and the like.
  • edetates such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na
  • hydroxyethylethylenediaminetriacetate such as HEDTA3Na
  • pentetate diethylenetriaminepentaacetate
  • phytic acid etidronate and the like.
  • Salts of phosphonic acid and its sodium salt; sodium oxalate; polypolyamino acids such as polyaspartic acid and polyglutamic acid; sodium polyphosphate, sodium metaphosphate, phosphoric acid; sodium citrate, citric acid, alanine, dihydroxyethylglycine , Gluconic acid, ascorbic acid, succinic acid and tartaric acid are preferred.
  • pH adjusters, acids, and alkalis include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, monoethanol.
  • the powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, phlogopite, biotite, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate, silica.
  • sodium chloride-containing salts such as common salt, normal salt, rock salt, sea salt and natural salt
  • potassium chloride aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, ammonium chloride
  • sodium phosphate such as phosphoric acid 1Na / 2Na / 3Na, phosphoric acid Potassiums, calcium phosphates, and magnesium phosphates are preferred.
  • UV absorber para-aminobenzoic acid, para-aminobenzoic acid monoglycerin ester, N, N-dipropoxy-para-aminobenzoic acid ethyl ester, N, N-diethoxy-para-aminobenzoic acid ethyl ester, N, N-dimethyl-para-aminobenzoic acid ethyl ester
  • Benzoic acid type ultraviolet absorbers such as esters, N, N-dimethylparaaminobenzoic acid butyl ester, N, N-dimethylparaaminobenzoic acid ethyl ester
  • anthranilic acid type ultraviolet absorbers such as homomenthyl-N-acetylanthranilate
  • salicylic acid And its sodium salts amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate
  • Benzophenone External radiation absorber 3- (4'-methylbenzylidene) -d, l-camphor, 3-benzylidene-d, l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5- 2- (2'-hydroxy-5'-t-octylphenyl) benzotriazole; 2- (2'-hydroxy-5'-methylphenylbenzotriazole; dibenzalazine; dianisoylmethane; 5- (3 , 3-Dimethyl-2-norbornylidene) -3-pentan-2-one; dibenzoylmethane derivatives such as 4-t-butylmethoxydibenzoylmethane; octyltriazone; urocanic acid derivatives such as urocanic acid and ethyl urocanate; 2- (2'-hydroxy-5'-methylphenyl) benzotriazole, 1- Hydantoin derivatives such as 3,4-d
  • vitamins and derivatives thereof include vitamins A such as retinol, retinol acetate, retinol palmitate; thiamine hydrochloride, thiamine sulfate, riboflavin, riboflavin acetate, pyridoxine hydrochloride, pyridoxine dioctanoate, pyridoxine dipalmitate, Flavin adenine dinucleotide, cyanocobalamin, folic acid, nicotinic acid such as nicotinamide / benzyl nicotinate, vitamin B group such as choline; vitamin C such as ascorbic acid and its sodium salt; vitamin D; ⁇ , Vitamin Es such as ⁇ , ⁇ and ⁇ -tocopherol; other vitamins such as pantothenic acid and biotin; ascorbic acid phosphoric acid ester salts such as sodium salt of ascorbic acid phosphoric acid ester and magnesium salt of ascorbic acid phosphoric acid ester; Ascor
  • Anti-inflammatory agents / anti-inflammatory agents include glycyrrhizic acid and its derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, prednisone, difedamine, hydrochloride, chlorpheniramine maleate; peach leaf extract.
  • Preferable examples are plant extracts such as peony leaf extract.
  • hair-growth agents examples include plant extracts and tinctures such as assembly extract, capsicum tincture, ginger tincture, ginger extract, canthari tincture; capsaicin, nonyl acid exertylamide, zingerone, ictamol, tannic acid.
  • Ester / inositol hexanicotinate, derivatives of nicotine alcohol, allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, Flavanonol derivatives, stigmasterol or stigmasteranol and its glycosides, minoxidil are preferred.
  • Preferred examples of hormones include estradiol, estrone, ethinyl estradiol, cortisone, hydrocortisone, and prednisone.
  • Other medicinal agents such as anti-wrinkle agents, anti-aging agents, tightening agents, cooling agents, warming agents, wound healing promoters, stimulants, analgesics, and cell activating agents include retinols, retinoic acids, retinoin.
  • Tocopheryl acid lactic acid, glycolic acid, gluconic acid, fruit acid, salicylic acid and derivatives thereof such as glycosides and esterified products, hydroxycapric acid, long-chain ⁇ -hydroxy fatty acid, long-chain ⁇ -hydroxy fatty acid cholesteryl, and other ⁇ - or ⁇ -hydroxy acids and derivatives thereof; ⁇ -aminobutyric acid, ⁇ -amino- ⁇ -hydroxybutyric acid; carnitine; carnosine; creatine; ceramides, sphingosines; caffeine, xanthine, etc.
  • coenzyme Q10 carotene, lycopene , Astaxanthin, lutein, ⁇ -lipoic acid, platinum nanocolloid, fullerenes, etc.
  • Antioxidants / active oxygen scavengers catechins; flavones such as quercetin; isoflavones; gallic acid and ester sugar derivatives; polyphenols such as tannin, sesamin, protoanthocyanidins, chlorogenic acid, apple polyphenols; rutin and glycosides Derivatives of hesperidin and glycosides; lignan glycosides; licorice extract-related substances such as glabridin, glabrene, liquiritin and isoliquiritin; lactoferrin; shogaol, zingerol; fragrance substances such as menthol, camphor, cedrol and derivatives thereof Capsaicin, vanillin and the like and derivatives; insect repellents such as diethylto
  • iris extract As plant, animal and microbial extracts, iris extract, ashitaba extract, asunaro extract, asparagus extract, avocado extract, amacha extract, almond extract,retea extract, arnica extract, aloe extract, apricot extract, apricot kernel extract, ginkgo biloba extract , Chinese chive extract, fennel extract, turmeric extract, oolong tea extract, arbutus extract, ages extract, gardenia leaf extract, neem extract, barley extract, psyllium extract, laurel extract, barley extract, ginseng extract, iris extract, sardine extract, ononis extract.
  • Extract Jatoba extract, Peony extract, Ginger extract, Ginger root extract, White birch extract, White jellyfish extract, Horsetail extract, Stevia extract, Stevia fermented product, Nishikawayanagi extract, Astragalus membranaceus extract, Hawthorn extract, Sambucus nigra extract, Achillea millefolium extract , Mint extract, sage extract, mallow extract, senkyu extract, senburi extract, soybean extract, rhubarb extract, da Izu extract, turmeric extract, thyme extract, dandelion extract, lichen extract, tea extract, clove extract, chigaya extract, chimpi extract, tea tree oil, beet tea extract, capsicum extract, touki extract, daffodil extract, tonin extract, spruce extract, dokudami extract, tomato.
  • Extract natto extract, carrot extract, garlic extract, nova extract, hibiscus extract, bakumondou extract, lotus extract, parsley extract, birch extract, honey, hamamelis extract, parietalia extract, Hikiokoshi extract, bisabolol, cypress extract, bifidobacteria extract, Loquat extract, coltsfoot extract, butterbur extract, butterbur extract, butcher bloom extract, grape extract, grape seed extract, propolis, loofah extract Safflower extract, peppermint extract, bodhiju extract, button extract, hop extract, mica extract, pine extract, horse chestnut extract, mizuba extract, makuji extract, melissa extract, mozuku extract, peach extract, cornflower extract, eucalyptus extract, yukinoshita extract, yuzu extract, lily extract.
  • Yokuinin extract mugwort extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, rooibos tea extract, litchi extract, lettuce extract, lemon extract, forsythia extract, astragalus extract, rose extract, rosemary extract, Roman chamomile extract, Extracts such as royal jelly extract and oleander extract are preferred.
  • Examples of the antipruritic agent include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, substance-P inhibitor and the like.
  • Examples of the keratin exfoliating / dissolving agent include salicylic acid, sulfur, resorcin, selenium sulfide, pyridoxine and the like.
  • Examples of antiperspirants include chlorohydroxyaluminum, aluminum chloride, zinc oxide, zinc paraphenol sulfonate, and the like.
  • Examples of the cooling agent include menthol and methyl salicylate.
  • Examples of the astringent include citric acid, tartaric acid, lactic acid, aluminum / potassium sulfate, tannic acid and the like.
  • the enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, protease and the like.
  • Preferred nucleic acids include ribonucleic acid and salts thereof, deoxyribonucleic acid and salts thereof, and adenosine triphosphate disodium.
  • fragrance acetyl cedrene, amylcinnamaldehyde, allyl amyl glycolate, ⁇ -ionone, iso-e-super, isobutylquinoline, iris oil, iron, indole, ylang-ylang oil, undecanal, undecenal, ⁇ -undecalactone, Estragal, Eugenol, Oakmoss, Opoponax Resinoid, Orange Oil, Eugenol, Auranthiol, Garasolid, Carvacrol, L-Carvone, Camphor, Canon, Carrot Seed Oil, Clove Oil, Methyl Cyanate, Geraniol, Geranyl Nitrile , Isobornyl acetate, geranyl acetate, dimethylbenzylcarbinyl acetate, styrylyl acetate, cedolyl acetate, terepinel acetate, pt-butylcyclohexyl acetate
  • pearl pigments such as titanium oxide coated mica, titanium oxide coated bismuth oxychloride, titanium oxide coated talc, colored titanium oxide coated mica, bismuth oxychloride and fish scale foil; aluminum powder, kappa Powder, metal powder pigments such as gold; surface-treated inorganic and metal powder pigments; red 201, red 202, red 204, red 205, red 220, red 226, red 228, red 405, orange No. 203, Orange No. 204, Yellow No. 205, Yellow No. 401, Blue No. 404, Red No. 3, Red No. 104, Red No. 106, Red No. 227, Red No. 230, Red No. 401, Red No. 505, Orange No. 205 , Yellow No.
  • organic pigments such as zirconium, barium or aluminum lake; surface-treated organic pigments; anthraquinones such as astaxanthin, alizarin, etc.
  • water normal water, purified water, hard water, soft water, natural water, deep sea water, electrolyzed alkaline ionized water, electrolyzed acidic ionized water, ionized water, and clustered water are preferred.
  • cosmetics raw material standards blending component standards by cosmetic varieties, Japan Cosmetic Industry Association component labeling name list, INCI dictionary (The International Cosmetic Ingredient Dictionary and Handbook), Quasi-drug raw material standards, Japanese Pharmacopoeia, pharmaceutical additives Ingredients listed in standards, food additive compendial documents, etc., and in Japanese and foreign patent gazettes and patent gazettes (including publication gazettes and republications) whose international patent classification IPC is A61K7 and A61K8 It is possible to incorporate known cosmetic ingredients, pharmaceutical ingredients, food ingredients, etc., such as the listed ingredients, in known combinations and blending ratios / blending amounts.
  • the types of cosmetics of the present invention include hair cosmetics, basic cosmetics, makeup cosmetics, fragrance cosmetics, body cosmetics, and external skin preparations such as ointments. From the viewpoint of exerting the effect of the present invention, it can be preferably used particularly in hair cosmetics and basic cosmetics.
  • the cosmetic of the present invention can be manufactured according to a usual method.
  • hair cosmetics oil shampoos, cream shampoos, conditioning shampoos, dandruff shampoos, hair color shampoos, shampoos such as rinse-integrated shampoos; rinses, treatments, Conditioners for hair packs, hair mists, etc .; Hair foams, hair mousses, hair sprays, hair waxes, hair gels, hair creams, water greases, set lotions, pomades, tics, etc .; hair lotions, hair tonics, hair liquids, hair blows, branches. Hair coat, hair oil, permanent wave agent, straight perm agent, oxidative hair dye, hair bleach, hair color pretreatment, hair color aftertreatment, perm pretreat Cement, permanent after-treatments, hair manicure, and as hair growth agents are preferred.
  • emollient lotion moisturizing lotion, milky lotion, nourishing lotion, nourishing milk, skin moisturizer, moisturizer -Emulsions, massage lotions, cleansing lotions, protect emulsions, sun protects, sun protectors, UV care milks, sunscreens, makeup lotions, keratin smoothers, elbow lotions, hand lotions, body lotions, etc .
  • emollient creams nutrition creams, Nourishing cream, vanishing cream, moisture cream, night cream, massage cream, cleansing cream, makeup cream, basek Cream, pre-makeup cream, sunscreen cream, suntan cream, depilatory cream, deodorant cream, shaving cream, keratin softening cream, gel such as moisture gel, moisturizing essence, whitening essence, UV protection essence, etc.
  • Liposomal cosmetics such as liposomal beauty liquid and liposomal lotion
  • packs and masks such as peel-off packs, powder packs, washing packs, oil packs and cleansing masks
  • white powder / dusting powder foundations, lipsticks, lip gloss, blusher, eyeliner, mascara, eye shadow, eyebrow, eyebrow, nail enamel, enamel remover, nail treatment are preferred. ..
  • perfume, perfume, eau de perfume, eau de toilette, cologne, perfume, fragrance powder, perfume soap, body lotion, and bath oil are preferred as fragrance cosmetics.
  • body cleansing agents such as body shampoos, deodorant lotions, deodorant powders, deodorant sprays, deodorant cosmetics such as deodorant sticks, decolorizing agents, depilatory / depilatory agents, bath agents, insect repellent insects, etc.
  • a repeller is mentioned as a preferable one.
  • an external preparation for skin it can be used in a dosage form such as an ointment, a patch, a lotion, a liniment and a liquid coating agent. It can also be used as an oral cosmetic such as toothpaste or mouthwash.
  • Examples of the dosage form of the cosmetic or external preparation for skin of the present invention include oil-in-water (O / W) type, water-in-oil (W / O) type, W / O / W type, O / W / O type and the like.
  • Type cosmetics oily cosmetics, solid cosmetics, liquid cosmetics, paste cosmetics, stick cosmetics, volatile oil type cosmetics, powder cosmetics, jelly cosmetics, gel cosmetics, pastes
  • Dosage forms such as cosmetics, emulsion polymer type cosmetics, sheet-shaped cosmetics, mist-shaped cosmetics, and spray-type cosmetics are mentioned as preferable ones.
  • Average degree of polymerization of inulin composition was measured under the following conditions.
  • Raftyrin ST average degree of polymerization 11
  • Raftyrin HP average degree of polymerization 22
  • HPLC conditions Column: TOSOH TSK-GEL G3000PWXL (7.8 x 300 mm)
  • Solvent Water Flow rate: 0.5 mL / min
  • Temperature 50 ° C
  • Detector Differential refractometer
  • Distribution of degree of polymerization of inulin composition In the present invention, the state of distribution of degree of polymerization of the inulin composition was measured using an ion chromatographic analyzer.
  • the distribution state of the degree of polymerization of the inulin composition of the present invention (Fuji FF) of the present invention obtained in Production Example 1 and a typical inulin product is as shown in FIG. 1 (extracted from Non-Patent Document 1). From the results of FIG.
  • Example 2 in which the inulin composition of the present invention was dissolved in 10% by weight, but the storage stability is improved by using a white jellyfish polysaccharide, hyaluronic acid, and xanthan gum in combination. I found out.
  • a lotion having the composition shown in Table 2 was prepared using the inulin composition of Production Example 1.
  • a lotion containing chicory inulin and a lotion containing no inulin were prepared.
  • the obtained lotion was evaluated according to the following evaluation criteria for two items, a sticky feeling during application and a dry feeling after drying. The results were shown based on the average score of the five panelists according to the following criteria. The results are shown in Table 2.
  • a skin cleanser having the composition shown in Table 3 was prepared.
  • a skin cleanser using chicory inulin and a skin cleanser containing no inulin were prepared.
  • the obtained skin cleansing agent was evaluated for fineness of foam, sticky feeling of foam, dry feeling after washing, and moist feeling after washing.
  • the fineness of bubbles was confirmed using a microscope and evaluated based on the following evaluation criteria.
  • the sensory evaluation was performed according to the following evaluation criteria, and based on the average score of the five panelists, the following judgment criteria were shown. The results are shown in Table 3.
  • the inulin composition of the present invention is excellent in the effect of improving the foam quality, and is also excellent in the feeling of use such as a dry feeling and a moist feeling after washing, as compared with chicory inulin having a wide degree of polymerization distribution. Met. Further, it was found that the combined use of Glycyrrhiza polysaccharide and hyaluronic acid improves the foam quality improving effect.
  • ⁇ Epidermal hyaluronic acid production promotion evaluation> Normal human epidermal cells were cultured for 48 hours in the medium to which the inulin composition of the present invention was added at each concentration shown in Table 4, and then the amount of hyaluronic acid in the medium supernatant was quantified by the ELISA method. From the quantitative results, the hyaluronic acid production promoting rate was calculated assuming that the amount of hyaluronic acid when cultured in the medium of the present invention without addition of the inulin composition was calculated, and the results are also shown in Table 4.
  • the premix composition and cosmetics described below were prepared.
  • the obtained cosmetic had excellent moisturizing properties, reduced stickiness, and imparted a feeling of dryness to use, and had improved foam quality in the detergent.
  • Example 12 Premix composition (Preparation method) Part A was heated to 50 ° C. and dissolved. Part B was uniformly dissolved. Part B was slowly added with stirring at room temperature to form a uniform liquid.
  • Part B was mixed to prepare a viscous liquid. Part A was heated to about 80 ° C. and uniformly dissolved. After slowly adding Part B to Part A with stirring and cooling to 40 ° C., Part C and Part D were added to form a uniform liquid.
  • Example 14 Lotion (Preparation method) Part A was mixed and slowly added to part B with stirring. Further, parts C and D that had been mixed in advance were added to obtain a uniform liquid.
  • Moisturizing lotion (Preparation method) Part A was heated to about 80 ° C. and mixed uniformly. Part B was added to make a uniform liquid.
  • Moisturizing lotion (Preparation method) Part A was uniformly dissolved at about 80 ° C., and part B was added to form a uniform liquid.
  • Example 17 Gel lotion (Preparation method) Part A was heated to about 70 ° C. and uniformly dispersed. Part B was mixed, well stirred, and homogenized, and then heated to about 70 ° C. Part B was added to part A, the mixture was stirred at about 70 ° C. using a homomixer, cooled to about 40 ° C., and part C was added.
  • Example 18 Transparent gel (Preparation method) Part A was stirred to form a uniform liquid. Part B was mixed to make a viscous liquid. Part B and part C were added to part A to make them uniform.
  • Emulsion Preparation method
  • Part A and part E were each heated to about 70 ° C. and uniformly dissolved.
  • Part B was stirred to give a viscous liquid.
  • Part C was heated to about 70 ° C. and uniformly dispersed.
  • Part C was added with stirring with a homodisper, and then part E was added with stirring.
  • Part D and part B were added at about 50 ° C., and stirred to dissolve uniformly.
  • Emulsion Preparation method
  • Part A, part B, and part D were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed.
  • Part C was mixed and stirred to give a viscous liquid.
  • part D was added and emulsified.
  • parts C and E were added, and the mixture was stirred and cooled to about 40 ° C.
  • Example 21 Skin care cream (Preparation method) Part A, part B, and part D were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to give a viscous liquid. After stirring part A with a homodisper and adding part B, part D was added and emulsified. After cooling, at about 50 ° C., parts C and E were added, and the mixture was stirred and cooled to about 40 ° C.
  • Example 22 Skin care cream (Preparation method) Part A and part C were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part B was mixed and stirred to give a viscous liquid. Part D was mixed to form a uniform liquid. While stirring part C with a homomixer, part A was added and emulsified. After cooling, at about 50 ° C, parts B and D were added, and the mixture was stirred and cooled to about 40 ° C.
  • Example 23 Skin care cream (Preparation method) Part A and part C were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part B was mixed and stirred to give a viscous liquid. Part D was mixed to form a uniform liquid. While stirring part C with a homomixer, part A was added and emulsified. After cooling, at about 50 ° C, parts B and D were added, and the mixture was stirred and cooled to about 40 ° C.
  • Example 24 Skin care cream (Preparation method) Part A, part B, and part D were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to give a viscous liquid. After stirring part A with a homodisper and adding part B, part D was added and emulsified. After cooling, at about 50 ° C, parts C and E were added, and the mixture was stirred and cooled to about 40 ° C.
  • Example 25 Skin care cream (Preparation method) Part A, part B, and part D were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to give a viscous liquid. Part E was mixed to form a uniform liquid. After stirring part A with a homodisper and adding part B, part D was added and emulsified. After cooling, at about 50 ° C, parts C and E were added, and the mixture was stirred and cooled to about 40 ° C.
  • Example 26 hand cream (Preparation method) Part B was heated to about 70 ° C. and dissolved. Part A was placed in another container and heated to about 80 ° C. for dissolution. The A part was added to the B part with stirring with a homomixer and emulsified. After the emulsification, the mixture was cooled to about 40 ° C., part C was added, and the mixture was mixed uniformly.
  • Example 27 hand cream (Preparation method) After dissolving part B, part A was added and heated to about 70 ° C. (part E). Part C was brought to about 70 ° C. C part was added to E part with stirring, and the mixture was stirred and mixed with a homomixer for about 3 minutes. After cooling to about 40 ° C., the mixed part D was added and uniformly mixed.
  • Example 28 hand cream (Preparation method) Part B and part C were each heated to about 80 ° C. and dissolved. Part A was placed in another container, heated to 100 to 120 ° C., turned into a transparent gel and cooled to 80 ° C. Part B was added to part A with stirring, and part C was further added to emulsify. After cooling to about 40 ° C., the mixed part D was added and uniformly mixed.
  • Emulsion (Preparation method) Parts A to C were taken, heated to about 70 ° C., and uniformly mixed. After gradually adding the B part to the A part with stirring with a homodisper, the C part was added at about 70 ° C. and emulsified. After cooling to about 40 ° C., the mixed part D was added and uniformly mixed.
  • Example 30 Gel lotion (Preparation method) Part A was heated to about 70 ° C. and uniformly dispersed. Part B was mixed, well stirred, and homogenized, and then heated to about 70 ° C. Part B was added to part A, stirred at about 70 ° C. using a homomixer, and cooled to about 40 ° C. The mixed part C was added and mixed uniformly.
  • Example 31 Cleansing gel (Preparation method) Part A and part B were each heated to about 80 ° C. and dissolved. Mix and warm to about 80 ° C. While stirring, part B was gradually added to part A, and after mixing, the mixture was cooled to 40 ° C. Part C was added and mixed uniformly.
  • Example 32 Cleansing cream (Preparation method) Part A and part B were each heated to about 80 ° C. and dissolved. Mix and warm to about 80 ° C. While stirring, part B was gradually added to part A, and after mixing, the mixture was cooled to 40 ° C. Part C was added and mixed uniformly.
  • Face wash foam (Preparation method) Part A was heated to about 80 ° C. and dissolved. Part B is heated to about 80 ° C. While stirring, part B was gradually added to part A, and after mixing, the mixture was cooled to 40 ° C. Part C was added and mixed uniformly.
  • Example 35 Body shampoo (Preparation method) Part A was heated at about 80 ° C. and uniformly mixed with stirring. The mixture was cooled to about 40 ° C., Part B was added, and the mixture was mixed uniformly.
  • Example 36 Body shampoo (Preparation method) Part A was heated at about 80 ° C. and uniformly mixed with stirring. The mixture was cooled to about 40 ° C., Part B was added, and the mixture was mixed uniformly.
  • Non-silicone shampoo (Preparation method) Part A was heated at about 80 ° C. and uniformly mixed with stirring. The mixture was cooled to about 40 ° C., Part B was added, and the mixture was mixed uniformly.
  • Example 38 hand soap (Preparation method) Part A was heated to about 80 ° C. and dissolved. Part B was added to part A, and the mixture was heated to about 80 ° C. and uniformly dissolved. The mixture was cooled to about 40 ° C. and part C was added to homogenize.
  • Example 40 Hair treatments that do not wash off (Preparation method) Part B was heated to about 80 ° C. and dissolved. Next, Part A was heated to about 80 ° C. and dissolved. Part D was dispersed to give a viscous liquid. Part A was added to part B with stirring, and after uniformly mixing, the mixture was cooled to about 40 ° C. Then, parts C, D and E were added and mixed uniformly.
  • Non-rinse scalp / hair treatment (Preparation method) Part A was heated to about 50 ° C. and dissolved. Next, the part B was uniformly dispersed to obtain a viscous liquid. Part A was added to part B with stirring and mixed uniformly. Then, parts C and D were added and mixed uniformly.
  • Non silicone hair treatment (Preparation method) Part A was uniformly mixed at about 80 ° C. Part B, which was set aside, was heated to about 60 ° C. and made uniform. Part B was gradually added to part A with stirring, and the mixture was mixed uniformly and then cooled to about 50 ° C. Further, part C was added and mixed uniformly.
  • Example 45 shampoo (Preparation method) Part B was heated to about 80 ° C. and uniformly dissolved. Part A was placed in another container, heated and dissolved. Part B was gradually added to part A and mixed uniformly, and part C was added at about 60 ° C. The mixture was cooled to about 40 ° C., Part D was added, and the mixture was mixed uniformly.
  • Example 46 shampoo (Preparation method) Part A was uniformly mixed at about 80 ° C. Part B, which was set aside, was heated to about 60 ° C. and made uniform. Part B was gradually added to part A with stirring, and the mixture was mixed uniformly and then cooled to about 50 ° C. Further, part C was added and mixed uniformly.
  • Example 48 Leave on hair treatment (Preparation method) Part C was heated to about 80 ° C. and dissolved. Next, Part A was heated to about 80 ° C. and dissolved. Part C was added with stirring, and part A was mixed and then cooled to about 40 ° C. Then, parts B and D were added and mixed uniformly.
  • Example 50 Styling milk (Preparation method) Part A and part B were mixed at about 80 ° C. Part B was added to part A to emulsify and after cooling to about 60 ° C. part C was added. Cool to about 40 ° C., mix with Part D and homogenize.
  • Example 51 Hair color treatment (Preparation method) Part A, which had been uniformly mixed in advance, was added to part B and heated to about 80 ° C. to dissolve (part F). Part D was heated to about 80 ° C. in another container and dissolved. The D part was gradually added to the F part while stirring and mixed uniformly, and then rapidly cooled (G part). C part and E part were added to G part which became about 40 ° C. to make it uniform.
  • Example 53 Water-containing gloss (Preparation method) Part A and part B were each melted by heating, and part B was added to part A, mixed, and then cooled to about 40 ° C.
  • Example 54 Water-containing gloss (Preparation method) Part A and part B were each melted by heating and made uniform, and part A was mixed with part B. The mixture was cooled to about 40 ° C, Part D was added, and the mixture was mixed uniformly.
  • Example 55 Liquid foundation (Preparation method) Part A, part B, and part C were heated and mixed. After adding B part to A part and making it emulsify, it cooled to about 50 degreeC, and stirred until it added C part and D part and became uniform.
  • Example 56 Liquid foundation (Preparation method) After heating and stirring Part A at 70 ° C., Part C was added and dispersed. This was heated to 70 ° C. in advance, added to the part B and emulsified and dispersed. It was cooled to about 40 ° C. and mixed uniformly.
  • Part A was heated to about 70 ° C., stirred well, and uniformly dispersed. After heating Part B to about 70 ° C. and making it uniform, Part B was added to Part A, and the mixture was emulsified with stirring at about 70 ° C. and cooled to about 40 ° C.
  • Example 58 Base cream (Preparation method) Part A and part B were dissolved by heating in separate containers. After adding B part to A part and making it emulsify, C part was added and mixed uniformly. After stirring, it was cooled to 40 ° C.
  • Example 59 Sunscreen cosmetics (Preparation method) Part A was added to part B and stirred. Further C was added and dispersed using a roller mill. Part D was heated and melted, added to the mixture of parts A, B and C, and part E was added to about 70 ° C. Part F was warmed and gradually emulsified into the mixture of parts A to E with stirring. The mixture was cooled with stirring, and part G was added at 40 to 35 ° C. and mixed uniformly.
  • Example 60 Sunscreen cosmetics (Preparation method) Part A was uniformly dispersed. Part B and part C were dissolved by heating at about 70 ° C. After gradually adding Part B to Part A, Part C was gradually added and emulsified. The mixture was cooled with stirring, and part D was added and stirred at 45 ° C.
  • Example 62 cream (Preparation method) Part A and part B were dissolved by heating and dispersed uniformly. The B part was gradually added to the A part to emulsify, and the dispersed C part was mixed and cooled with stirring. Part C was added at about 40 ° C. and mixed uniformly.
  • Example 63 Skin care oil (Preparation method) Part A was heated to 50 ° C., uniformly dissolved, and cooled to room temperature. Part B was heated to 80 ° C, uniformly dissolved, and cooled to about 40 ° C. Mixed with Part A and Part B.
  • ⁇ LP70H Hydrogenated lysolecithin
  • LUSPLAN DD-IS Diisostearic acid dimer dilinoleyl
  • LUSPLAN PI-DA Dimer dilinoleic acid di (isostearyl / phytosteryl)
  • LUSPLAN DD-DHR Dye mergin linoleil hydrogenated rosin condensate
  • LUSPLAN DD-DA5 Die merlin linoleic acid daimer linoleyl
  • LUSPLAN DD-DA7 Die mer linoleic acid daimer linoleyl
  • LUSPLAN SR-DP4 Die Dimergino linoleic acid, pentaerythrityl tetraisostearate
  • LUSPLAN SR-DM4 Dimer dilinoleic acid di mergin

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Abstract

L'invention concerne un produit cosmétique caractérisé en ce qu'il contient une composition d'inulines dans laquelle le degré moyen de polymérisation de toutes les inulines est compris entre 13 et 23 et des inulines ayant un degré de polymérisation entre 5 et 29 comprennent au moins 95% en masse dans 100% en masse de toutes les inulines.
PCT/JP2018/041592 2018-11-09 2018-11-09 Produit cosmétique WO2020095425A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/JP2018/041592 WO2020095425A1 (fr) 2018-11-09 2018-11-09 Produit cosmétique
CN201880099362.7A CN113015515B (zh) 2018-11-09 2018-11-09 化妆品

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