WO2017191158A1 - Systems and methods for driving negative pressure sources in negative pressure therapy systems - Google Patents

Systems and methods for driving negative pressure sources in negative pressure therapy systems Download PDF

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Publication number
WO2017191158A1
WO2017191158A1 PCT/EP2017/060470 EP2017060470W WO2017191158A1 WO 2017191158 A1 WO2017191158 A1 WO 2017191158A1 EP 2017060470 W EP2017060470 W EP 2017060470W WO 2017191158 A1 WO2017191158 A1 WO 2017191158A1
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WO
WIPO (PCT)
Prior art keywords
negative pressure
source
driving circuit
driving
actuator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2017/060470
Other languages
English (en)
French (fr)
Inventor
Ben Alan ASKEM
Victoria Beadle
John Philip GOWANS
Mark Hesketh
Allan Kenneth Frazer Grugeon HUNT
William KELBIE
Damyn Musgrave
Joseph William Robinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith and Nephew PLC
Original Assignee
Smith and Nephew PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith and Nephew PLC filed Critical Smith and Nephew PLC
Priority to US16/098,604 priority Critical patent/US11305047B2/en
Priority to EP17721366.7A priority patent/EP3452131B1/en
Priority to JP2018555866A priority patent/JP6975172B2/ja
Priority to CA3022587A priority patent/CA3022587A1/en
Priority to CN201780025727.7A priority patent/CN109069711A/zh
Priority to AU2017259003A priority patent/AU2017259003B2/en
Publication of WO2017191158A1 publication Critical patent/WO2017191158A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/96—Suction control thereof
    • A61M1/962—Suction control thereof having pumping means on the suction site, e.g. miniature pump on dressing or dressing capable of exerting suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71—Suction drainage systems
    • A61M1/74—Suction control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/96—Suction control thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/96—Suction control thereof
    • A61M1/966—Suction control thereof having a pressure sensor on or near the dressing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0272—Electro-active or magneto-active materials
    • A61M2205/0294—Piezoelectric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/10—General characteristics of the apparatus with powered movement mechanisms
    • A61M2205/106—General characteristics of the apparatus with powered movement mechanisms reciprocating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated
    • A61M2205/8212—Internal energy supply devices battery-operated with means or measures taken for minimising energy consumption

Definitions

  • Embodiments of the present disclosure relate to methods and apparatuses for dressing and treating a wound with negative or reduced pressure therapy or topical negative pressure (TNP) therapy.
  • embodiments disclosed herein relate to negative pressure therapy devices, methods for controlling the operation of TNP systems, and methods of using TNP systems.
  • an apparatus for applying negative pressure to a wound can include a source of negative pressure, a coupling circuit, a driving circuit, and a controller.
  • the source of negative pressure can provide negative pressure via a fluid flow path to a wound dressing placed over the wound.
  • the source of negative pressure can include an actuator configured to convert an electrical energy to a mechanical energy.
  • the coupling circuit can include an inductive reactance.
  • the driving circuit can supply a driving signal to the actuator via the coupling circuit to cause the source of negative pressure to provide negative pressure.
  • the controller can control the driving signal supplied by the driving circuit.
  • the apparatus of the preceding paragraph can include one or more of the following features:
  • the actuator can generate negative pressure by converting the electrical energy to the mechanical energy without converting the electrical energy to a magnetic energy.
  • the source of negative pressure can include a piezoelectric pump, and the actuator can include a piezoelectric transducer.
  • the source of negative pressure can include a micropump.
  • the apparatus can further include the wound dressing, and the source of negative pressure can be disposed on or within the wound dressing.
  • the coupling circuit can limit a rate of change over time of the driving signal supplied from the driving circuit to the actuator.
  • the inductive reactance can be greater than 5 mQ at an operating frequency of 1 kHz.
  • the coupling circuit can include an inductor electrically coupled in series between an output of the driving circuit and an input of the actuator.
  • the inductor can have an inductance between 1 ⁇ and 100 ⁇ .
  • the inductor can have a maximum current rating of at least 1 A.
  • the coupling circuit can include an electrical short electrically coupled in series between another output of the driving circuit and another input of actuator.
  • the driving circuit can include an H-bridge circuit.
  • the controller can further provide a control signal to the driving circuit, and the controller can control the driving signal by adjusting a pulse width modulation of the control signal.
  • a magnitude of the driving signal can be less than 50 V.
  • a method of operating a negative pressure wound therapy apparatus can include: generating and outputting a control signal; activating a plurality of switches responsive to the control signal; supplying a driving signal to an actuator of a source of negative pressure via the plurality of switches; limiting a rate of change over time of the driving signal; and supplying negative pressure with the source of negative pressure to a wound dressing responsive to the driving signal.
  • the method of the preceding paragraph can include one or more of the following features:
  • the limiting the rate of change over time can include limiting the rate of change over time using an inductive reactance.
  • the supplying negative pressure can be performed by converting an electrical energy to a mechanical energy without converting the electrical energy to a magnetic energy.
  • the activating the plurality of switches can include activating pairs of the plurality of switches responsive to the control signal.
  • the control signal can include a square waveform having a duty cycle of 50%.
  • FIG. 1 illustrates a negative pressure therapy system according to some embodiments.
  • FIGS. 2A and 2B respectively illustrate a side view and top view of a negative pressure therapy system according to some embodiments, such as the negative pressure therapy system of FIG. 1.
  • FIG. 3 illustrates a block diagram of electrical communication paths between a power source, control circuitry, and negative pressure source, as well as components of the control circuitry, according to some embodiments.
  • FIGS. 4A and 4B illustrate simplified circuit components of a driving circuit according to some embodiments.
  • FIG. 4C illustrates circuit components of a driving circuit according to some embodiments.
  • FIG. 5 illustrates circuit components of a coupling circuit according to some embodiments.
  • FIG. 6 illustrates a therapy control process performable by a negative pressure therapy system according to some embodiments.
  • the present disclosure relates to methods and apparatuses for dressing and treating a wound with reduced pressure therapy or topical negative pressure (TNP) therapy.
  • TNP topical negative pressure
  • embodiments of this disclosure relate to negative pressure therapy apparatuses, methods for controlling the operation of TNP systems, and methods of using TNP systems.
  • the methods and apparatuses can incorporate or implement any combination of the features described below.
  • TNP therapy sometimes referred to as vacuum assisted closure, negative pressure wound therapy, or reduced pressure wound therapy, can be a beneficial mechanism for improving the healing rate of a wound.
  • Such therapy is applicable to a broad range of wounds such as incisional wounds, open wounds and abdominal wounds or the like.
  • TNP therapy can assist in the closure and healing of wounds by reducing tissue oedema, encouraging blood flow, stimulating the formation of granulation tissue, removing excess exudates, and reducing bacterial load and thus, infection to the wound. Furthermore, TNP therapy can permit less outside disturbance of the wound and promote more rapid healing.
  • reduced or negative pressure levels represent pressure levels that are below atmospheric pressure, which typically corresponds to 760 mmHg (or 1 atm, 29.93 inHg, 101.325 kPa, 14.696 psi, etc.).
  • a negative pressure value of -X mmHg reflects pressure that is X mmHg below atmospheric pressure, such as a pressure of (760-X) mmHg.
  • negative pressure that is "less” or "smaller” than -X mmHg corresponds to pressure that is closer to atmospheric pressure (e.g., -40 mmHg is less than -60 mmHg).
  • Negative pressure that is "more” or “greater” than -X mmHg corresponds to pressure that is further from atmospheric pressure (e.g., -80 mmHg is more than -60 mmHg).
  • a driving circuit of a TNP apparatus can supply a driving signal (for example, an electrical current and voltage) to a negative pressure source of the TNP apparatus via a coupling circuit of the TNP apparatus.
  • the negative pressure source can include a pump like a piezoelectric pump or micropump.
  • the coupling circuit can have an inductive reactance that limits a rate of change over time of the driving signal supplied by the driving circuit to the negative pressure source.
  • the TNP apparatus having such a construction may consume less power to generate negative pressure than other TNP apparatuses.
  • FIG. 1 illustrates a negative pressure therapy system 100 that includes a TNP apparatus 1 1 and a wound 14 according to some embodiments.
  • the TNP apparatus 1 1 can be used to treat the wound 14.
  • the TNP apparatus 1 1 can include control circuitry 12A, memory 12B, a negative pressure source 12C, a user interface 12D, a power source 12E, a first pressure sensor 12F, and a second pressure sensor 12G that are configured to electrically communicate with one another.
  • the TNP apparatus 1 1 can include a wound dressing 13.
  • the power source 12E can provide power to one or more components of the TNP apparatus 1 1.
  • control circuitry 12A, memory device 12B, negative pressure source 12C, user interface 12D, power source 12E, first pressure sensor 12F, and second pressure sensor 12G can be integral with, incorporated as part of, attached to, or disposed in the wound dressing 13.
  • the TNP apparatus 1 1 can accordingly be considered to have its control electronics and pump on-board the wound dressing 13 rather than separate from the wound dressing 13.
  • the control circuitry 12A can include one or more controllers (for example, a microcontroller or microprocessor), activation circuits, boost converters, current limiters, feedback conditioning circuits, and H-bridge inverters.
  • the control circuitry 12A can control the operations of one or more other components of the TNP apparatus 1 1 according at least to instructions stored in the memory device 12B.
  • the control circuitry 12A can, for instance, control operations of and supply of negative pressure by the negative pressure source 12C.
  • the negative pressure source 12C can include a pump, such as, without limitation, a rotary diaphragm pump or other diaphragm pump, a piezoelectric pump, a peristaltic pump, a piston pump, a rotary vane pump, a liquid ring pump, a scroll pump, a pump operated by a piezoelectric transducer, or any other suitable pump or micropump or any combinations of the foregoing.
  • the pump can include an actuator driven by a source of energy, such as electrical energy, mechanical energy, and the like.
  • the actuator can be an electric motor, a piezoelectric transducer, a voice coil actuator, an electroactive polymer, a shape-memory alloy, a comb drive, a hydraulic motor, a pneumatic actuator, a screw jack, a servomechanism, a solenoid actuator, a stepper motor, a plunger, a combustion engine, and the like.
  • the negative pressure source 12C can supply negative pressure by converting electrical energy to mechanical energy without converting the electrical energy to magnetic energy.
  • the negative pressure source 12C can have a different impact when electrically coupled to one or more other components of the control circuitry 12A than if the negative pressure source 12C supplied negative pressure by converting the electrical energy to the magnetic energy and then to the mechanical energy.
  • the user interface 12D can include one or more elements that receive user inputs or provide user outputs to a patient or caregiver.
  • the one or more elements that receive user inputs can include buttons, switches, dials, touch screens, or the like, and the one or more elements that provide user outputs can include activation of a light emitting diode (LED) or one or more pixels of the display or activation of a speaker or the like.
  • the user interface 12D can include a switch to receive user inputs (for instance, a negative pressure activation or deactivation input) and two LEDs to indicate an operating status (for example, functioning normally, under fault condition, or awaiting user input) of the TNP apparatus 1 1.
  • the first pressure sensor 12F can be used to monitor pressure underneath the wound dressing 13, such as pressure in a fluid flow path connecting the negative pressure source 12C and the wound 14, pressure at the wound 14, or pressure in the negative pressure source 12C.
  • the second pressure sensor 12G can be used to monitor pressure external to the wound dressing 13.
  • the pressure external to the wound dressing can be atmospheric pressure; however, the atmospheric pressure can vary depending on, for instance, an altitude of use or pressurized environment in which the TNP apparatus 1 1 may be used.
  • the control circuitry 12A can control the supply of negative pressure by the negative pressure source 12C according at least to a comparison between the pressure monitored by the first pressure sensor 12F and the pressure monitored by the second pressure sensor 12G.
  • the wound dressing 13 can include a wound contact layer, a spacer layer, and an absorbent layer.
  • the wound contact layer can be in contact with the wound 14.
  • the wound contact layer can include an adhesive on the patient facing side for securing the dressing to the skin surrounding the wound 14 or on the top side for securing the wound contact layer to a cover layer or other layer of the wound dressing 13.
  • the wound contact layer can provide unidirectional flow so as to facilitate removal of exudate from the wound while blocking or substantially preventing exudate from returning to the wound 14.
  • the spacer layer can assist in distributing negative pressure over the wound site and facilitating transport of wound exudate and fluids into the wound dressing 13.
  • the absorbent layer can absorb and retain exudate aspirated from the wound 14.
  • the control circuitry 12A can monitor the activity of the negative pressure source 12C, which may include monitoring a duty cycle of the negative pressure source 12C (for example, the duty cycle of the actuator of the negative pressure source).
  • a duty cycle of the negative pressure source 12C for example, the duty cycle of the actuator of the negative pressure source.
  • the "duty cycle” can reflect the amount of time the negative pressure source 12C is active or running over a period of time. In other words, the duty cycle can reflect time that the negative pressure source 12C is in an active state as a fraction of total time under consideration.
  • Duty cycle measurements can reflect a level of activity of the negative pressure source 12C. For example, the duty cycle can indicate that the negative pressure source 12C is operating normally, working hard, working extremely hard, etc.
  • the duty cycle measurements can reflect various operating conditions, such as presence or severity of leaks, rate of flow of fluid (for instance, air, liquid, or solid exudate, etc.) aspirated from a wound, or the like.
  • the controller can execute or be programmed to execute algorithms or logic that control the operation of the system.
  • duty cycle measurements can indicate presence of a high leak, and the control circuitry 12A can be programmed to indicate this condition to a user (for instance, patient, caregiver, or physician) or temporarily suspend or pause operation of the source of negative pressure in order to conserve power.
  • the wound dressing 13 can create a substantially sealed or closed space around the wound 13 and under the wound dressing 13, and the first pressure sensor 12F can periodically or continuously measure or monitor a level of pressure in this space.
  • the control circuitry 12A can control the level of pressure in the space between a first negative pressure set point limit and at least a second negative pressure set point limit.
  • the first set point limit can be approximately -70 mmHg, or from approximately -60 mmHg or less to approximately -80 mmHg or more.
  • the second set point limit can be approximately -90 mmHg, or from approximately -80 mmHg or less to approximately -100 mmHg or more.
  • FIG. 2A illustrates a side view of a negative pressure therapy system 200
  • FIG. 2B illustrates a top view of the negative pressure therapy system 200 according to some embodiments.
  • the negative pressure therapy system 200 can be an example implementation of the negative pressure therapy system 100.
  • the wound dressing 13 of the TNP apparatus 1 1 is shown as attached to the wound 14. Arrows depict the flow of air through the wound dressing 13 and wound exudate from the wound 14.
  • the TNP apparatus 1 1 can include an air exhaust 26 and a component area 25, such as a components housing or storage area for components of the TNP apparatus 1 1 like one or more of the control circuitry 12A, memory device 12B, negative pressure source 12C, user interface 12D, power source 12E, first pressure sensor 12F, and second pressure sensor 12G.
  • the user interface 12D of the negative pressure therapy system 200 can include a switch 21 (such as a dome switch), a first indicator 23 (such as a first LED), and a second indicator 24 (such as a second LED).
  • the switch 21 can receive a negative pressure activation or deactivation user input (for example, such as receiving the activation or deactivation user input in response to depression of the switch 21 for a period of time, like from between 0.5 seconds and 5 seconds).
  • the first indicator 23 and the second indicator 24 can indicate an operating status like functioning normally, under fault condition, or awaiting user input.
  • the switch 21 can couple to a power supply connection of the negative pressure source 12C or the control circuitry 12A or an enable signal of the negative pressure source 12C or the control circuitry 12A to activate or deactivate supply of negative pressure or disable supply of negative pressure.
  • FIG. 3 illustrates a block diagram 300 depicting example electrical communication paths between the power source 12D, control circuitry 12A, and negative pressure source 12C, as well as example components of the control circuitry 12A including a controller 31 , a current limiter 32, a driving circuit 33, a feedback conditioner 34, and the coupling circuit 35.
  • FIG. 3 shows, in particular, how the controller 31 can be used to control the supply of negative pressure by the negative pressure source 12C according to some embodiments.
  • the power source 12D can include one or more power supplies, such as batteries (such as, multiple 3 V batteries) or a connection to mains power, to provide power for one or more components of the TNP apparatus 1 1 .
  • the power source 12D can, for instance, provide electrical current and voltage to the current limiter 32.
  • the voltage output by the power source 12D can be around 30 V, such as 29 V ⁇ 1 V, in some implementations.
  • the power source 12D can additionally include circuitry, such as a boost converter, to control the electrical current and voltage provided to the current limiter 32.
  • the current limiter 32 can serve to limit or clamp the current at a maximum current level, such as at 100 mA, 250 mA, 466 mA, 500 mA, or 1 A, to limit potential fault current through the driving circuit 33 and the negative pressure source 12C. Under normal operation (for example, in most or some instances), the current limiter 32 may not operate to limit current or voltage.
  • the current limiter 32 can provide electric current and voltage to the driving circuit 33.
  • the driving circuit 33 can include an H-bridge circuit composed of multiple switches.
  • the H-bridge can be constructed to operate as an H-bridge inverter.
  • the driving circuit 33 can provide feedback to the controller 31 via the feedback conditioner 34.
  • the feedback conditioner 34 can be used, for instance, to condition current feedback information from the driving circuit 33 before the current feedback information is provided to the controller 31.
  • the feedback conditioner 34 can include a low-pass filter (which can, for example, include active circuit components) to filter switching noise caused by the switching of one or more switches of the driving circuit 33.
  • the controller 31 can, in turn, control the operations of the driving circuit 33 based on the feedback, in some instances.
  • the controller 31 can control operations of the driving circuit 33, and in turn the negative pressure source 12C, by outputting one or more control signals via one or more outputs of the controller 31 to one or more inputs of the driving circuit 33.
  • the controller 31 can output a first control signal via a first output 01 of the controller 31 to a first input 11 of the driving circuit 33 and a second control signal via a second output 02 of the controller 31 to a second input I2 of the driving circuit 33.
  • the controller 31 can vary a pulse width modulation (PWM) of the first and second control signals to adjust an electrical current and voltage provided by the driving circuit 33 to the coupling circuit 35 and then to the negative pressure source 12C.
  • PWM pulse width modulation
  • the electrical current or voltage provided by the driving circuit 33 may, in some instances, be referred to herein as a driving signal.
  • the driving circuit 33 can include an H- bridge, and the controller 31 can generate the first and second control signals to cause the H-bridge to output the driving signal having a square waveform (such as ⁇ 3 V, ⁇ 5 V, ⁇ 10 V, ⁇ 15 V, ⁇ 20 V, ⁇ 25 V, ⁇ 30 V, or ⁇ 40 V) with a frequency (such as 10 kHz to 32 kHz, 14 kHz to 28kHz, 18 kHz to 24 kHz, 20 KHz to 22 KHz, or about 21 kHz) and a duty cycle or ratio (such as 20%, 30%, 40%, 45%, 50%, 55%, 60%, 70%, or 80%) via a first output O1 of the driving circuit 33 and a second output O2 of the driving circuit 33.
  • a square waveform such as ⁇ 3 V, ⁇ 5 V, ⁇ 10 V, ⁇ 15 V, ⁇ 20 V, ⁇ 25 V, ⁇ 30 V, or ⁇ 40 V
  • a frequency such as 10 kHz to 32
  • the driving circuit 33 can control supply negative pressure by the negative pressure source 12C by providing the driving signal to the negative pressure source 12C (for example, to the actuator of the negative pressure source 12C) via the coupling circuit 35.
  • the driving circuit 33 can, for instance, output electrical currents via the first and second outputs O1 and 02 of the driving circuit 33 to a first input 11 of the coupling circuit 35 and a second input I2 of the coupling circuit 35.
  • the coupling circuit 35 can, in turn, output electrical currents via a first output 01 of the coupling circuit 35 and a second output 02 of the coupling circuit 35 to a first input 11 of the negative pressure source 12C and a second input I2 of the negative pressure source 12C.
  • the electrical currents output by the driving circuit 33 and the coupling circuit 35 can notably be considered to result in positive charge flowing away from the driving circuit 33 (that is, sourcing of electrical current by the driving circuit 33) or toward the driving circuit 33 (that is, sinking of electrical current by the driving circuit 33).
  • the coupling circuit 35 can serve to limit a rate of change over time of the current supplied by the driving circuit 33 to the negative pressure source 12C or limit a rate of change over time of a voltage across first and second inputs 11 and I2 of the negative pressure source 12C.
  • the coupling circuit 35 can have an inductive reactance greater than 1 mQ, 5 mO, 10 mQ, 50 mQ, 100 mQ, 500 mQ, 750 mQ at an operating frequency of 1 kHz.
  • the coupling circuit 35 can include passive circuit elements and not include active circuit elements, but in other embodiments, the coupling circuit 35 can include one or both of passive circuit elements and active circuit elements.
  • FIGS. 4A and 4B illustrate example simplified circuit components of the driving circuit 33 according to some embodiments.
  • the driving circuit 33 can be composed of at least four switches, including a first switch S1 , a second switch S2, a third switch S3, and a fourth switch S4 but together form an H-bridge.
  • the first and fourth switches S1 and S4 can be closed at the same time and the second and third switches S2 and S3 can be opened at the same time, as shown in FIG. 4A, to supply a first current i1 in a first direction through the coupling circuit 35 and the negative pressure source 12C.
  • the second and third switches S2 and S3 can be closed at the same time and the first and fourth switches S1 and S4 can be opened at the same time, as shown in FIG. 4B, to supply a second current i2 in a second direction through the coupling circuit 35 and the negative pressure source 12C.
  • the first direction can be opposite the second direction.
  • FIG. 4C illustrates example circuit components of the driving circuit 33 (an H-bridge in the illustrated example) that include a resistor 42 according to some embodiments.
  • the electrical current that travels through the resistor 42 can be the same or substantially the same as the electrical current that travels through the coupling circuit 35 and the negative pressure source 12C (for example, the actuator of the negative pressure source 12C).
  • a feedback provided to the feedback conditioner 34 can, for instance, be a voltage level or drop across the resistor 42, which can be proportional to the electrical current that travels through the resistor 42, as well as the electrical current that travels through the coupling circuit 35 and the negative pressure source 12C.
  • the resistor 42 thus can be used to measure one or more properties of the electrical current, such as a magnitude, that is fed to the negative pressure source 12C via the coupling circuit 35, such as via an inductor of the coupling circuit 35 like an inductor 52 described with respect to FIG. 5.
  • the resistor 42 can be coupled to a low-pass filter, as described herein.
  • FIG. 5 illustrates example circuit components of the coupling circuit 35 according to some embodiments.
  • the coupling circuit 35 can include (i) the inductor 52 electrically coupled in series between the first output 01 of the driving circuit 33 and the first input 11 of the negative pressure source 12C and (ii) a wire or an electrical short 54 electrically coupled in series between the second output 02 of the driving circuit 23 and the second input I2 of the negative pressure source 12C.
  • the inductor can have an inductance ranging from 0.1 ⁇ to 1000 ⁇ , 1 ⁇ to 100 ⁇ , or 3 ⁇ to 10 ⁇ , or an inductance of about 7.5 ⁇ .
  • the inductor can have a maximum current rating of greater than 0.25 A, 0.5 A, 0.75 A, 1 A, or 1.25 A.
  • the inductor 52 can be used to oppose rapid changes in a current or voltage supplied to drive the negative pressure source 12C.
  • the coupling circuit 35 can include (i) a first wire or a first electrical short electrically coupled in series between the first output 01 of the driving circuit 33 and the first input 11 of the negative pressure source 12C and (ii) a second wire or a second electrical short electrically coupled in series between the second output 02 of the driving circuit 33 and the second input I2 of the negative pressure source 12C.
  • the coupling circuit 35 can include (i) a first wire or a first electrical short electrically coupled in series between the first output 01 of the driving circuit 33 and the first input 11 of the negative pressure source 12C and (ii) an inductor (such as the inductor 52) electrically coupled in series between the second output 02 of the driving circuit 33 and the second input I2 of the negative pressure source 12C.
  • the coupling circuit 35 can include (i) a first inductor (such as the inductor 52) electrically coupled in series between the first output 01 of the driving circuit 33 and the first input 11 of the negative pressure source 12C and (ii) a second inductor (such as the inductor 52) electrically coupled in series between the second output 02 of the driving circuit 33 and the second input I2 of the negative pressure source 12C.
  • a first inductor such as the inductor 52
  • a second inductor such as the inductor 52
  • one or more active elements can be used in place of or in addition to one or more inductors.
  • FIG. 6 illustrates a therapy control process 600 performable by an apparatus, such as the TNP apparatus 1 1 according to some embodiments.
  • the therapy control process 600 is described in the context of the TNP apparatus 1 1 , but may instead be implemented in other systems described herein, or by other systems not shown.
  • the therapy control process 600 can generate and output a control signal.
  • the controller 31 can generate and output a control signal to the driving circuit 33.
  • the therapy control process 600 can activate switches responsive to the control signal.
  • the driving circuit 33 can selectively open and close one or more switches of the driving circuit 33 responsive to the control signal.
  • the therapy control process 600 can supply a driving signal via the switches.
  • the driving circuit 33 can supply the driving signal to the coupling circuit 35 via opening and closing of the one or more switches of the driving circuit 33.
  • the therapy control process 600 can limit a rate of change over time of the driving signal.
  • the coupling circuit 35 can limit a rate of change over time of the driving signal from the driving circuit 33 using an inductive reactance.
  • the therapy control process 600 can supply negative pressure responsive to the driving signal.
  • the negative pressure source 33 can supply negative pressure to the wound dressing 13 responsive to the driving signal provided by the driving circuit 33 via the coupling circuit 35.
  • any value of a threshold, limit, duration, etc. provided herein is not intended to be absolute and, thereby, can be approximate.
  • any threshold, limit, duration, etc. provided herein can be fixed or varied either automatically or by a user.
  • relative terminology such as exceeds, greater than, less than, etc. in relation to a reference value is intended to also encompass being equal to the reference value. For example, exceeding a reference value that is positive can encompass being equal to or greater than the reference value.
  • relative terminology such as exceeds, greater than, less than, etc. in relation to a reference value is intended to also encompass an inverse of the disclosed relationship, such as below, less than, greater than, etc. in relations to the reference value.
  • blocks of the various processes may be described in terms of determining whether a value meets or does not meet a particular threshold, the blocks can be similarly understood, for example, in terms of a value (i) being below or above a threshold or (ii) satisfying or not satisfying a threshold.
  • the various components illustrated in the figures may be implemented as software or firmware on a processor, controller, ASIC, FPGA, or dedicated hardware.
  • Hardware components such as processors, ASICs, FPGAs, and the like, can include logic circuitry.
  • User interface screens illustrated and described herein can include additional or alternative components. These components can include menus, lists, buttons, text boxes, labels, radio buttons, scroll bars, sliders, checkboxes, combo boxes, status bars, dialog boxes, windows, and the like. User interface screens can include additional or alternative information. Components can be arranged, grouped, displayed in any suitable order.
  • Conditional language such as “can,” “could,” “might,” or “may,” unless specifically stated otherwise, or otherwise understood within the context as used, is generally intended to convey that certain embodiments include, while other embodiments do not include, certain features, elements, or steps. Thus, such conditional language is not generally intended to imply that features, elements, or steps are in any way required for one or more embodiments or that one or more embodiments necessarily include logic for deciding, with or without user input or prompting, whether these features, elements, or steps are included or are to be performed in any particular embodiment.
  • the terms “comprising,” “including,” “having,” and the like are synonymous and are used inclusively, in an open-ended fashion, and do not exclude additional elements, features, acts, operations, and so forth.
  • the term "or” is used in its inclusive sense (and not in its exclusive sense) so that when used, for example, to connect a list of elements, the term “or” means one, some, or all of the elements in the list.
  • the term “each,” as used herein, in addition to having its ordinary meaning, can mean any subset of a set of elements to which the term “each” is applied.
  • the terms “generally parallel” and “substantially parallel” refer to a value, amount, or characteristic that departs from exactly parallel by less than or equal to 15 degrees, 10 degrees, 5 degrees, 3 degrees, 1 degree, or 0.1 degree.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Accommodation For Nursing Or Treatment Tables (AREA)
PCT/EP2017/060470 2016-05-03 2017-05-03 Systems and methods for driving negative pressure sources in negative pressure therapy systems Ceased WO2017191158A1 (en)

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US16/098,604 US11305047B2 (en) 2016-05-03 2017-05-03 Systems and methods for driving negative pressure sources in negative pressure therapy systems
EP17721366.7A EP3452131B1 (en) 2016-05-03 2017-05-03 Systems and methods for driving negative pressure sources in negative pressure therapy systems
JP2018555866A JP6975172B2 (ja) 2016-05-03 2017-05-03 陰圧療法システムにおける陰圧源を駆動するためのシステム及び方法
CA3022587A CA3022587A1 (en) 2016-05-03 2017-05-03 Systems and methods for driving negative pressure sources in negative pressure therapy systems
CN201780025727.7A CN109069711A (zh) 2016-05-03 2017-05-03 用于在负压力治疗系统中驱动负压源的系统和方法
AU2017259003A AU2017259003B2 (en) 2016-05-03 2017-05-03 Systems and methods for driving negative pressure sources in negative pressure therapy systems

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US201662331109P 2016-05-03 2016-05-03
US62/331109 2016-05-03
US201762479592P 2017-03-31 2017-03-31
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