WO2016206523A3 - 一种胶体果胶铋或含胶体果胶铋制剂中铋含量的测定方法 - Google Patents

一种胶体果胶铋或含胶体果胶铋制剂中铋含量的测定方法 Download PDF

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WO2016206523A3
WO2016206523A3 PCT/CN2016/083739 CN2016083739W WO2016206523A3 WO 2016206523 A3 WO2016206523 A3 WO 2016206523A3 CN 2016083739 W CN2016083739 W CN 2016083739W WO 2016206523 A3 WO2016206523 A3 WO 2016206523A3
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bismuth
pectin
colloidal
content
measuring
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PCT/CN2016/083739
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English (en)
French (fr)
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WO2016206523A2 (zh
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李安平
崔锋
朱平
秦正国
郑台
吴月侠
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山西振东安特生物制药有限公司
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Priority to AU2016284236A priority Critical patent/AU2016284236B2/en
Priority to EP16813639.8A priority patent/EP3315945B1/en
Priority to US15/548,096 priority patent/US20180017497A1/en
Priority to JP2017558679A priority patent/JP6524260B2/ja
Publication of WO2016206523A2 publication Critical patent/WO2016206523A2/zh
Publication of WO2016206523A3 publication Critical patent/WO2016206523A3/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/46—Pectin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Plasma & Fusion (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

一种胶体果胶铋或含胶体果胶铋制剂中铋含量的测定方法，是以质子酸将铋从胶体果胶铋中解离出来，利用铋与碘化钾生成黄色碘化铋钾的特征反应原理，采用紫外一可见分光光度法测定，以外标法计算得到铋含量。
PCT/CN2016/083739 2015-06-23 2016-05-27 一种胶体果胶铋或含胶体果胶铋制剂中铋含量的测定方法 WO2016206523A2 (zh)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2016284236A AU2016284236B2 (en) 2015-06-23 2016-05-27 Method for measuring bismuth content in colloidal bismuth pectin or colloidal bismuth pectin-containing preparation
EP16813639.8A EP3315945B1 (en) 2015-06-23 2016-05-27 Method for measuring bismuth content in colloidal bismuth pectin or colloidal bismuth pectin-containing preparation
US15/548,096 US20180017497A1 (en) 2015-06-23 2016-05-27 Method for measuring bismuth content in colloidal bismuth pectin or colloidal bismuth pectin-contained preparation
JP2017558679A JP6524260B2 (ja) 2015-06-23 2016-05-27 コロイドペクチンビスマス又はコロイドペクチンビスマス含有製剤におけるビスマス含有量の測定方法

Applications Claiming Priority (2)

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CN201510348311.1 2015-06-23
CN201510348311.1A CN104880428B (zh) 2015-06-23 2015-06-23 一种胶体果胶铋或含胶体果胶铋制剂中铋含量的测定方法

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WO2016206523A2 WO2016206523A2 (zh) 2016-12-29
WO2016206523A3 true WO2016206523A3 (zh) 2017-02-09

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US (1) US20180017497A1 (zh)
EP (1) EP3315945B1 (zh)
JP (1) JP6524260B2 (zh)
CN (1) CN104880428B (zh)
AU (1) AU2016284236B2 (zh)
WO (1) WO2016206523A2 (zh)

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CN104880428B (zh) * 2015-06-23 2016-07-06 山西振东安特生物制药有限公司 一种胶体果胶铋或含胶体果胶铋制剂中铋含量的测定方法
CN104897668B (zh) * 2015-06-23 2016-08-24 山西振东安特生物制药有限公司 用于检测含胶体果胶铋制剂溶出度的方法
CN107314982A (zh) * 2017-06-30 2017-11-03 湖北惠生药业有限公司 一种紫外分析维生素b6粗品含量的方法
CN107807105A (zh) * 2017-12-13 2018-03-16 江苏力凡胶囊有限公司 一种测定胶囊囊材中二氧化钛含量的方法
CN108169153A (zh) * 2017-12-27 2018-06-15 佛山市南海东方澳龙制药有限公司 检测复方酮康唑软膏中甲硝唑含量的方法
CN109991184B (zh) * 2018-01-02 2022-01-21 山西振东安特生物制药有限公司 胶体果胶铋或含胶体果胶铋制剂中游离铋的检测方法
CN110146500B (zh) * 2018-02-12 2021-07-23 山西振东安特生物制药有限公司 测定胶体果胶铋或含胶体果胶铋制剂中游离铋的方法
CN109633000A (zh) * 2018-12-25 2019-04-16 湖北丽益医药科技有限公司 枸橼酸铋钾及其制剂中游离铋的检测方法
CN110389105B (zh) * 2019-06-25 2022-03-15 湖南九典制药股份有限公司 一种胶体果胶铋中游离铋的检测方法
CN112067506B (zh) * 2020-09-22 2024-02-13 北京鑫开元医药科技有限公司 一种含枸橼酸铋钾制剂的粘度测定方法

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Publication number Publication date
EP3315945A4 (en) 2018-12-05
AU2016284236A1 (en) 2017-12-21
CN104880428B (zh) 2016-07-06
CN104880428A (zh) 2015-09-02
WO2016206523A2 (zh) 2016-12-29
EP3315945A2 (en) 2018-05-02
US20180017497A1 (en) 2018-01-18
AU2016284236B2 (en) 2018-12-06
EP3315945B1 (en) 2020-07-08
JP2018517132A (ja) 2018-06-28
JP6524260B2 (ja) 2019-06-05

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