WO2015195452A3 - Systèmes et procédés de filtration à simple passage - Google Patents

Systèmes et procédés de filtration à simple passage Download PDF

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Publication number
WO2015195452A3
WO2015195452A3 PCT/US2015/035250 US2015035250W WO2015195452A3 WO 2015195452 A3 WO2015195452 A3 WO 2015195452A3 US 2015035250 W US2015035250 W US 2015035250W WO 2015195452 A3 WO2015195452 A3 WO 2015195452A3
Authority
WO
WIPO (PCT)
Prior art keywords
tangential flow
flow filtration
pass tangential
processes
pass
Prior art date
Application number
PCT/US2015/035250
Other languages
English (en)
Other versions
WO2015195452A2 (fr
WO2015195452A4 (fr
Inventor
Herbert Lutz
Joseph Parrella
Bala Raghunath
Original Assignee
Emd Millipore Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emd Millipore Corporation filed Critical Emd Millipore Corporation
Publication of WO2015195452A2 publication Critical patent/WO2015195452A2/fr
Publication of WO2015195452A3 publication Critical patent/WO2015195452A3/fr
Publication of WO2015195452A4 publication Critical patent/WO2015195452A4/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B01D61/146—Ultrafiltration comprising multiple ultrafiltration steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/082—Flat membrane modules comprising a stack of flat membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/082—Flat membrane modules comprising a stack of flat membranes
    • B01D63/0822—Plate-and-frame devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/02—Membrane cleaning or sterilisation ; Membrane regeneration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/18—Specific valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2315/00—Details relating to the membrane module operation
    • B01D2315/10—Cross-flow filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2319/00—Membrane assemblies within one housing
    • B01D2319/02—Elements in series
    • B01D2319/022—Reject series
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2319/00—Membrane assemblies within one housing
    • B01D2319/04—Elements in parallel
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/04—Backflushing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/06—Use of osmotic pressure, e.g. direct osmosis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/16—Use of chemical agents
    • B01D2321/164—Use of bases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
    • Y10T29/49828—Progressively advancing of work assembly station or assembled portion of work

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne, dans divers modes de réalisation, des ensembles de filtration à écoulement tangentiel à simple passage hybrides, des ensembles de filtration à écoulement tangentiel à simple passage jetables, des ensembles de filtration à écoulement tangentiel à simple passage évolutifs et des ensembles de filtration à écoulement tangentiel à simple passage modulaires adaptables. Dans d'autres modes de réalisation, l'invention concerne des procédés de récupération de protéines sur la surface d'une membrane de filtration dans un ensemble de filtration à écoulement tangentiel à simple passage et de nettoyage d'un ensemble de filtration à écoulement tangentiel. Dans d'autres modes de réalisation, l'invention concerne des procédés d'augmentation de la capacité de traitement d'un ensemble de filtration à écoulement tangentiel à simple passage.
PCT/US2015/035250 2014-06-16 2015-06-11 Systèmes et procédés de filtration à simple passage WO2015195452A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462012792P 2014-06-16 2014-06-16
US62/012,792 2014-06-16

Publications (3)

Publication Number Publication Date
WO2015195452A2 WO2015195452A2 (fr) 2015-12-23
WO2015195452A3 true WO2015195452A3 (fr) 2016-02-11
WO2015195452A4 WO2015195452A4 (fr) 2016-03-31

Family

ID=53443036

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2015/035250 WO2015195452A2 (fr) 2014-06-16 2015-06-11 Systèmes et procédés de filtration à simple passage

Country Status (7)

Country Link
US (3) US10207225B2 (fr)
EP (1) EP3693080B1 (fr)
KR (2) KR101814245B1 (fr)
CN (1) CN105413463B (fr)
ES (2) ES2934615T3 (fr)
SG (1) SG10201504670RA (fr)
WO (1) WO2015195452A2 (fr)

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WO2015195453A2 (fr) 2014-06-16 2015-12-23 Emd Millipore Corporation Procédés pour augmenter la capacité de processus à écoulement continu
US10207225B2 (en) 2014-06-16 2019-02-19 Emd Millipore Corporation Single-pass filtration systems and processes
US10399039B2 (en) 2014-06-25 2019-09-03 Emd Millipore Corporation Compact spiral-wound filter elements, modules and systems
CN108325391B (zh) 2014-08-29 2021-05-18 Emd 密理博公司 过滤液体进料的方法
SG10201901555UA (en) 2014-08-29 2019-03-28 Emd Millipore Corp Single Pass Tangential Flow Filtration Systems and Tangential Flow Filtration Systems withRecirculation of Retentate
DE102015122261B3 (de) * 2015-12-18 2017-01-12 Sartorius Stedim Biotech Gmbh Kassetteneinspannvorrichtung
US10183108B2 (en) * 2016-02-04 2019-01-22 Pall Corporation Inline diafiltration with multi-channel pump
WO2019079274A1 (fr) 2017-10-17 2019-04-25 Mar Cor Purification, Inc. Système d'eau à osmose inverse avec une fonction de transfert de chaleur
CA3078642A1 (fr) 2017-10-17 2019-04-25 Mar Cor Purification, Inc. Systeme universel de gestion de puissance de chauffage
WO2019079280A1 (fr) 2017-10-17 2019-04-25 Mar Cor Purification, Inc. Système de purification d'eau par osmose inverse multimode transportable
KR102527659B1 (ko) 2017-11-27 2023-05-03 삼성전자주식회사 공기청정기
JP7093518B2 (ja) * 2017-11-30 2022-06-30 東レ株式会社 ろ過装置
CN110241012B (zh) * 2018-03-09 2022-11-01 嘉和生物药业有限公司 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用
DE102018004909B4 (de) * 2018-06-19 2020-03-26 Sartorius Stedim Biotech Gmbh Modulares Prozessiersystem und Verfahren zum modularen Aufbau eines Prozessiersystems
CN112566920A (zh) * 2018-08-14 2021-03-26 百时美施贵宝公司 改善的蛋白质回收
KR20210082246A (ko) * 2018-11-30 2021-07-02 리플리겐 코포레이션 일회용 무균성 접선 유동 여과 시스템 및 방법

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