WO2015133358A1

WO2015133358A1 - Toothpaste composition

Info

Publication number: WO2015133358A1
Application number: PCT/JP2015/055591
Authority: WO
Inventors: 剛太郎飯泉
Original assignee: ライオン株式会社
Priority date: 2014-03-03
Filing date: 2015-02-26
Publication date: 2015-09-11
Also published as: MY180536A; KR102306478B1; KR20160120275A; JPWO2015133358A1; CN106029053B; JP6528762B2; CN106029053A

Abstract

Provided is a toothpaste composition that prevents bubbles dripping from the mouth during tooth brushing, that has superior bubble creaminess, that has good flavor, and that includes: (A) a high polymerization polyethylene glycol; (B) an alkyl sulfate; (C) an ampholytic surfactant; and (D) a non-ionic surfactant. The toothpaste composition is characterized in that the component (C)/component (D) mass ratio is 0.05-5. Also provided is a bubble-drip improvement method in which the components (C) and (D) are blended at the component (C)/component (D) mass ratio into a toothbrush composition having the components (A) and (B) are blended therein, and used together with the components (A) and (B) in the toothpaste composition.

Description

Toothpaste composition

The present invention relates to a toothpaste composition that suppresses foam dripping from the mouth when brushing teeth, has an excellent creamy feel, and has a high flavor.

Of the feeling of use of the dentifrice composition, the feeling of foam in the oral cavity is one of the textures that can give a feeling of cleaning. However, saliva is constantly secreted in the oral cavity, and especially if you brush your teeth for a long time, the dentifrice composition is diluted with saliva. As a result, there was a problem that bubbles dropped from the mouth, the creamy feeling of the bubbles was not felt, and the satisfaction of brushing the teeth was lowered.

Further, in order to improve the satisfaction of use of the dentifrice composition, good flavor standing at the start of tooth brushing is important. However, the surfactant generally used as a foaming agent has a problem that it develops the bitterness peculiar to it or reduces the expression of a fragrance to be blended for masking unpleasant taste.
For this reason, in a dentifrice composition, it was difficult to improve foam performance, maintaining favorable flavor standing.

Known methods for improving the feeling of foam and improving the feeling of use include blending silicic acid anhydride, betaine type amphoteric surfactant, l-menthol and menthyl ester, thereby improving foaming properties and texture. A technique has been proposed that gives a feeling of cleaning and cleaning with fine foam quality, suppresses bitterness and taste during use, and refreshes the mouth (Patent Document 1: Japanese Translation of PCT International Publication No. 2011-105647). However, this patent document 1 does not mention bubble dripping from the mouth.

On the other hand, polyethylene glycol is generally used as a humectant or thickener in the oral field, but there are few examples of blending highly polymerized polyethylene glycol having an average molecular weight of 50,000, particularly 100,000 or more, into the preparation. Examples used for improving foaming performance of liquid dentifrice compositions (Patent Document 2: JP 2006-506359 A) and examples used for dentifrice compositions excellent in the effect of promoting recalcification of teeth (Patent Document) 3: JP-A-2013-112613), a technique for improving foamability, foam persistence and creaminess when brushing teeth by blending highly polymerized polyethylene glycol, alkyl sulfate and thickening silica (Patent Document 4) : International Publication No. 10/073975) has been proposed. However, these Patent Documents 2 to 4 do not mention the flavor standing of the dentifrice composition.

Special table 2011-105647 gazette JP 2006-506359 A JP 2013-112613 A International Publication No. 10/073975

Therefore, in dentifrice compositions, there is a need for a technique for improving foam performance, particularly foam sag while maintaining good flavor standing.

The present invention has been made in view of the above circumstances, and an object of the present invention is to provide a toothpaste composition that suppresses foam dripping from the mouth when brushing teeth, is excellent in foam creaminess, and has a high flavor.

As a result of intensive studies to achieve the above object, the present inventor has obtained (A) highly polymerized polyethylene glycol, (B) alkyl sulfate, (C) amphoteric surfactant, and (D) nonionic surfactant. Containing (C) component / (D) component in a mass ratio of 0.05 to 5, foam dripping from the mouth during tooth brushing is suppressed, foam creamy feeling is excellent, and flavor is high It has been found that a toothpaste composition can be obtained.

That is, when the (B) component is used in combination with the (A) component in the toothpaste composition, especially when the blending amount of the (A) component and the (B) component is increased to further improve the feeling of use. Occasionally bubble dripping occurred, resulting in a problem that the flavor of the blended fragrance deteriorated. Therefore, as a result of further investigation, when the (C) and (D) components are combined with the (A) component together with the (B) component at an appropriate ratio (C) / (D), all the above problems are solved. It has been found that the dripping is suppressed, the creamy feeling of the foam is improved, and an excellent flavor can be imparted. In addition, it has been found that, particularly when (E) a fragrance selected from mint, spice and fruit is blended as a fragrance, the flavor standing is more excellent. Therefore, the toothpaste composition of the present invention is less likely to drip from the mouth when brushing teeth, gives a foam that can be held appropriately in the mouth, improves the creamy feeling of the foam, has a high flavor of the blended fragrance, and feels good to use Is excellent, and can provide sufficient toothpaste and satisfaction with use.

Accordingly, the present invention provides the following toothpaste composition and a method for improving bubble sag in the toothpaste composition.
[1]
(A) Highly polymerized polyethylene glycol, (B) alkyl sulfate, (C) amphoteric surfactant and (D) nonionic surfactant are contained, and (C) component / (D) component has a mass ratio of 0. A toothpaste composition characterized by having 5 to 5.
[2]
The highly polymerized polyethylene glycol as component (A) has a viscosity of 10 mPa · s or more at 25 ° C. measured at 25 ° C. measured with a Brookfield viscometer and 2 W / V at 25 ° C. measured with the viscometer. The toothpaste composition according to [1], wherein the% aqueous solution has a viscosity of 800 mPa · s or less.
[3]
(C) The toothpaste composition according to [1] or [2], wherein the component is a betaine amphoteric surfactant.
[4]
The (C) component betaine amphoteric surfactant is fatty acid amidopropyl betaine and / or 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolium betaine in [1], [2] or [3] The toothpaste composition as described.
[5]
The toothpaste composition according to any one of [1] to [4], wherein the component (D) is polyoxyethylene hydrogenated castor oil having an average addition mole number of ethylene oxide of 20 to 40.
[6]
Component (A) is 0.05 to 0.5% by mass, Component (B) is 1 to 3.5% by mass, Component (C) is 0.05 to 1% by mass, Component (D) is 0.1 to The toothpaste composition according to any one of [1] to [5], containing 3% by mass.
[7]
The toothpaste composition according to any one of [1] to [6], further comprising (E) a fragrance in an amount of 0.5 to 2.5% by mass.
[8]
(C) Amphoteric surfactant and (D) Nonionic surfactant, (C) Component / (D) component, in a toothpaste composition containing (A) highly polymerized polyethylene glycol and (B) alkyl sulfate Is blended in a mass ratio in the range of 0.05 to 5, in the method of improving bubble sag by the combined use of the components (A) and (B) in the toothpaste composition.
[9]
The highly polymerized polyethylene glycol as component (A) has a viscosity of 10 mPa · s or more at 25 ° C. measured at 25 ° C. measured with a Brookfield viscometer and 2 W / V at 25 ° C. measured with the viscometer. A method for improving bubble sag by combining the components (A) and (B) in the toothpaste composition according to [8], wherein the viscosity of the% aqueous solution is 800 mPa · s or less.
[10]
Component (A) is 0.05 to 0.5% by mass, Component (B) is 1 to 3.5% by mass, Component (C) is 0.05 to 1% by mass, Component (D) is 0.1 to A method for improving dripping by combining the components (A) and (B) in the toothpaste composition according to [8] or [9] containing 3% by mass.
[11]
Further, (E) Foam dripping due to the combined use of the components (A) and (B) in the toothpaste composition according to [8], [9] or [10] containing 0.5 to 2.5% by mass of a fragrance How to improve.

According to the present invention, it is possible to provide a toothpaste composition in which foam dripping from the mouth during brushing is suppressed, the creamy feeling of the foam is excellent, and the flavor is high. This toothpaste composition can provide sufficient toothpaste feeling and satisfaction with use.

Hereinafter, the present invention will be described in further detail. The toothpaste composition of the present invention comprises (A) highly polymerized polyethylene glycol, (B) alkyl sulfate, (C) amphoteric surfactant, (D) nonionic surfactant, and (C) component / ( D) The ratio of the component is within a specific range.

The highly polymerized polyethylene glycol of component (A) is a polymer compound having a structure in which ethylene glycol is polymerized, and is a 5 W / V (mass / volume (volume))% aqueous solution at 25 ° C. measured with a Brookfield viscometer. It is preferable that the viscosity is 10 mPa · s or more and the viscosity of the 2 W / V% aqueous solution at 25 ° C. measured by the viscometer is 800 mPa · s or less.
When the viscosity of the 5 W / V% aqueous solution exceeds 20,000 mPa · s, the viscosity cannot be measured, so the viscosity in the 2 W / V% aqueous solution is adopted. That is, in the present invention, the highly polymerized polyethylene glycol preferably has the following viscosity physical properties (1) or (2).
(1) Viscosity of 5 W / V% aqueous solution at 25 ° C. is 10 to 20,000 mPa · s
(2) In (1), when the viscosity exceeds 20,000 mPa · s, the viscosity of the 2 W / V% aqueous solution at 25 ° C. is 800 mPa · s or less. In the present invention, more preferable highly polymerized polyethylene glycol is 5 W at 25 ° C. The viscosity of the / V% aqueous solution is 10 to 18,000 mPa · s, particularly 30 to 10,000 mPa · s, especially 55 to 2,000 mPa · s.

In the present invention, by using highly polymerized polyethylene glycol having a viscosity within the above specific range as the component (A), it is possible to sufficiently contribute to the improvement of foam dripping from the mouth and to further improve the creamy feeling of the foam.
If the viscosity of the 5 W / V% aqueous solution is less than 10 mPa · s, it may not sufficiently contribute to the improvement of foam dripping from the mouth, and the effect of improving the creamy feeling of the foam may be inferior. When it exceeds 800 mPa · s, not only the flavor is deteriorated, but also the stability of the toothpaste composition may be lowered.

As the highly polymerized polyethylene glycol of component (A), the following commercially available products can be used.
・ POLYOX WSR N-10
(Manufactured by Dow Chemical Co., Ltd., viscosity of 5 W / V% aqueous solution: 12 to 50 mPa · s, measuring device: Brookfield RVT, rotor No. 1, rotation speed 50 rpm, measuring temperature 25 ° C., measuring time 0.5 minutes)
・ POLYOX WSR N-80
(Manufactured by Dow Chemical Co., Ltd., viscosity of 5 W / V% aqueous solution: 55 to 115 mPa · s, measuring equipment: Brookfield RVT, rotor No. 1, rotation speed 50 rpm, measuring temperature 25 ° C., measuring time 0.5 minutes)
・ POLYOX WSR N-750
(Viscosity of 5 W / V% aqueous solution manufactured by Dow Chemical Company: 1,000 to 1,200 mPa · s, measuring equipment: Brookfield RVF, rotor No. 2, rotation speed 10 rpm, measuring temperature 25 ° C., measuring time 1 minute )
・ POLYOX WSR-205
(Viscosity of 5 W / V% aqueous solution manufactured by Dow Chemical Company: 4,500-8,800 mPa · s, measuring equipment: Brookfield RVF, rotor No. 2, rotation speed 2 rpm, measuring temperature 25 ° C., measuring time 5 minutes )
・ POLYOX WSR-1105
(Viscosity of 5 W / V% aqueous solution manufactured by Dow Chemical Company: 8,800-17,600 mPa · s, measuring equipment: Brookfield RVF, rotor No. 2, rotation speed 2 rpm, measuring temperature 25 ° C., measuring time 5 minutes )
・ POLYOX WSR N-12K
(Dow Chemical Co., Ltd., viscosity of 2 W / V% aqueous solution: 400 to 800 mPa · s, measuring equipment: Brookfield RVF, rotor No. 1, rotation speed 10 rpm, measuring temperature 25 ° C., measuring time 1 minute)

(A) The blending amount of the highly polymerized polyethylene glycol is preferably 0.05 to 0.5% (mass%, the same applies hereinafter) of the whole composition, more preferably 0.1 to 0.3%. When the blending amount is 0.05% or more, the dripping from the mouth can be sufficiently improved, and the creamy feeling of the foam can be sufficiently improved. A content of 0.5% or less is suitable for suppressing deterioration in flavor.

In this invention, (B) alkyl sulfate is mix | blended as an anionic surfactant.
(B) As the alkyl sulfate, sodium alkyl sulfate such as sodium lauryl sulfate and sodium myristyl sulfate can be used, and sodium lauryl sulfate is particularly preferred from the standpoint of flavor. Specifically, sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd .; sodium lauryl sulfate), sodium myristyl sulfate (manufactured by Nikko Chemicals Co., Ltd .; NIKKOL SMS) and the like can be used.

(B) The amount of alkyl sulfate is preferably 1 to 3.5%, more preferably 1.5 to 2.5% of the total composition. If the blending amount is 1% or more, the creamy feeling of the foam can be improved. 3.5% or less is suitable for suppressing deterioration in flavor. Furthermore, in order to prevent the foaming property of the toothpaste composition from increasing too much and dripping the foam from the mouth, and to prevent the feeling of use such as irritation in the oral cavity from becoming worse, It is preferably not too much, and is preferably 3.5% or less.

(C) As an amphoteric surfactant, a betaine amphoteric surfactant can be suitably blended.
Examples of the betaine amphoteric surfactant include fatty acid amidopropyl betaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolium betaine, and the number of carbon atoms of the hydrocarbon group of the betaine amphoteric surfactant is 8-18 are preferred. Particularly preferred is fatty acid amidopropyl betaine having 8 to 18 carbon atoms in the fatty acid, and among these, coconut oil fatty acid amidopropyl betaine is more preferred from the standpoint of flavor.

(C) Amphoteric surfactant can use a commercial item, and specifically, the following are mentioned.
・ Palm oil fatty acid amidopropyl betaine (EVONIC, TEGO BETAIN CK OK)
2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolium betaine (manufactured by Lion Corporation; Enacol C-40H)

(C) The blending amount of the amphoteric surfactant is preferably 0.05 to 1% of the total composition in terms of pure content in terms of foamy creamy feeling, dripping from the mouth, and good taste. Preferably it is 0.1 to 1%, more preferably 0.1 to 0.5%. When the blending amount is 0.05% or more, the creamy feeling of the foam is improved, and the dripping from the mouth can be further suppressed. It is suitable for suppressing that the foaming property of a toothpaste composition increases too much and foam dripping from a mouth worsens that it is 1% or less. Furthermore, it is also preferable for preventing the bitterness peculiar to amphoteric surfactants from occurring.

(D) The nonionic surfactant is particularly preferably polyoxyethylene hydrogenated castor oil, more preferably polyoxyethylene hydrogenated castor oil having an average added mole number of ethylene oxide of 20 to 40, particularly 20.
As polyoxyethylene hydrogenated castor oil, polyoxyethylene (40) hydrogenated castor oil (manufactured by Nippon Emulsion Co., Ltd .: EMALEX HC-40, average number of moles of ethylene oxide added 40), polyoxyethylene (20) hydrogenated castor oil (Nippon Emulsion Co., Ltd .: EMALEX HC-20, average added mole number of ethylene oxide 20).

(D) The amount of the nonionic surfactant is preferably 0.1 to 3%, more preferably 0, based on the creamy feeling of the foam, the dripping from the mouth, and the flavor. .2 to 1.5%. When the blending amount is 0.1% or more, the creamy feeling of the foam is improved, and the dripping from the mouth can be further suppressed. 3% or less is suitable for suppressing deterioration in flavor.

In the present invention, by combining (C) amphoteric surfactant and (D) nonionic surfactant together with (B) alkyl sulfate as a surfactant within a specific range of (C) / (D), It can suppress dripping, improve the creamy feeling of the foam, and improve the flavor standing.
In this case, the blending ratio of (C) amphoteric surfactant and (D) nonionic surfactant is such that (C) / (D) is 0.05 to 5, preferably 0.1 to 5, more preferably 0.1 to 3, and still more preferably 0.5 to 1.5. Within the above range, there is no dripping of foam from the mouth, creamy feeling of the foam, and excellent flavor. If it is less than 0.05, the flavor is deteriorated. If it exceeds 5, the foaming properties of the toothpaste composition will increase excessively, and the creamy feeling of the foam will be impaired, and at the same time, dripping from the mouth will be severe.

In the present invention, the total content of the surfactant including the components (B), (C) and (D) is 1.15 to 7.5%, particularly 1.5 to 5.2% of the whole composition. In particular, the range of 2 to 4% is preferable. If it is within this range, the dripping of the foam can be further suppressed, and the creamy feeling of the foam is also more excellent. Moreover, flavor standing improves more. Furthermore, in this case, it is preferable that the total content is not too much to suppress the foaming property of the toothpaste composition from being excessively increased and to prevent the dripping of the foam from becoming worse and to prevent the flavor from becoming worse. Furthermore, it is also preferable for suppressing the bitterness derived from the surfactant.

In the present invention, surfactants other than the components (B), (C), and (D) may be blended as necessary within a range not impeding the effects of the present invention. Specifically, anionic surfactants other than alkyl sulfates, for example, N-acyl sarcosine salts such as N-lauroyl sarcosine sodium and N-myristoyl sarcosine sodium, N-acyl glutamate, N-methyl-N-acyl Examples include sodium taurine, sodium N-methyl-N-acylalanine, sodium α-olefin sulfonate, and the like. When blending these surfactants, it is preferable to blend them within the range of the total surfactant content described above.

The toothpaste composition of the present invention preferably further contains (E) a fragrance. As the fragrance, a natural fragrance added as a general fragrance for a dentifrice, a fragrance obtained by processing a natural fragrance, a single fragrance, a blended fragrance, and the like are known fragrance materials used in dentifrice compositions. One species can be used alone, or two or more species can be used in combination. In this case, in the present invention, even when the components (A) and (B) are combined, the flavor of the blended fragrance can be sufficiently exhibited. Preferable fragrances include mint-based fragrances, spice-based fragrances, and fruit-based fragrances. When these are used, particularly good flavor standing is obtained.

The blending amount of the fragrance of the component (E) is preferably 0.5 to 2.5%, more preferably 0.8 to 1.8% of the whole composition from the viewpoint of good flavor. As the amount is increased, the flavor is improved, and when 0.5% or more is blended, a good flavor can be imparted. A content of 2.5% or less is suitable for suppressing deterioration in flavor. When there are too many compounding quantities, it may become impossible to maintain favorable flavor standing.

In the toothpaste composition of the present invention, in addition to the above components, other known components can be blended as necessary within the range that does not interfere with the effects of the present invention. For example, an abrasive, a thickener, a binder, and a sweetener, a colorant, a preservative, a medicinal component, etc. can be blended if necessary. In addition, a compounding quantity may be a normal quantity in the range which does not prevent the effect of this invention.

As abrasives, silica-based abrasives such as silica gel, precipitated silica, aluminosilicate, zirconosilicate, dicalcium phosphate dihydrate and anhydrous, tertiary calcium phosphate, tetracalcium phosphate, calcium pyrophosphate, etc. Agents, calcium carbonate, aluminum hydroxide, alumina, zeolite, hydroxyapatite, synthetic resin abrasives, and the like. The blending amount of these abrasives is usually 2 to 50%, particularly 10 to 30% of the whole composition.

Examples of the thickener include sugar alcohols such as sorbit and xylit, and polyhydric alcohols such as glycerin and propylene glycol. In addition, polyethylene glycol having an average molecular weight of 190 to 2,000 (average molecular weight described in the specifications of raw materials for quasi drugs) is compatible with the component (A) which is a polymer, so that it can swell and disperse in the aqueous phase. It can be preferably used. The blending amount of these thickeners is usually preferably 5 to 50%, particularly preferably 20 to 45% of the whole composition.

As the binder, an organic or inorganic binder can be blended. Specifically, sodium carboxymethylcellulose, methylcellulose, hydroxymethylcellulose, cellulose derivatives such as cationized cellulose, alginic acid derivatives such as sodium alginate, propylene glycol alginate, gums such as xanthan gum, karaya gum, gum arabic, sodium polyacrylate, Examples thereof include organic binders such as polyvinyl alcohol, carboxyvinyl polymer, polyvinyl pyrrolidone, and carrageenan, and inorganic binders such as gelling silica, gelling aluminum silica, bee gum, and laponite. The amount of the binder is usually 0.1 to 10%, particularly preferably 0.5 to 5%.

Examples of the sweetening agent include saccharin sodium, stevioside, stevia extract and the like. Examples of the colorant include Red No. 2, No. 3, 225, No. 226, Yellow No. 4, No. 5, Blue No. 1, No. 2, Mica titanium, titanium oxide and the like.
Examples of the preservative include paraoxybenzoic acid esters such as methylparaben and ethylparaben, benzoic acid such as sodium benzoate, and salts thereof.

As the medicinal ingredients, known ingredients that are usually blended, such as bactericides, anti-inflammatory agents, enzymes, fluorides, copper compounds, vitamins, plant extracts, anticalculus agents, antiplaque agents, etc. of the present invention are used. An effective amount can be blended within a range that does not interfere with the effect.
Specifically, nonionic fungicides such as isopropylmethylphenol, cationic fungicides such as cetylpyridinium chloride, chlorhexidine hydrochloride, benzalkonium chloride, benzethonium chloride, tranexamic acid, epsilon aminocaproic acid, allantoin, glycyrrhetic acid, glycyrrhizin Anti-inflammatory agents such as dipotassium acid, enzymes such as dextranase, mutanase, amylase and protease, fluorides such as sodium fluoride and sodium monofluorophosphate, water-soluble phosphate compounds, copper compounds such as copper gluconate, potassium nitrate Inorganic salts such as aluminum lactate, zinc chloride, zinc citrate and strontium chloride, vitamins such as ascorbic acid and tocopherol acetate, plant extracts and the like.

Hereinafter, although an Example, a comparative example, and a formulation example are shown and this invention is demonstrated concretely, this invention is not restrict | limited to the following Example. In the following examples, “%” means “% by mass” unless otherwise specified.

[Examples and Comparative Examples]
Dentifrice compositions (toothpastes) having the compositions shown in Tables 1 to 3 were prepared by conventional methods and evaluated by the following methods. The results are shown in the table.

(1) Evaluation method of foam dripping from the mouth during brushing (hardness of foam dripping) Ten panelists extrude 1cm of dentifrice composition filled in a laminate tube onto a commercial toothbrush and brush the teeth for 3 minutes I got a response about the bubble dripping from the mouth while brushing my teeth in four stages: “No bubble dripping”, “Slight bubble dripping but no problem”, “Slight bubble dripping”, “Bubble dripping” . Out of this answer, 4 points for “No bubble dripping”, 3 points for “Slight bubble dripping but no problem”, 2 points for “Slight bubble dripping”, 1 point for “Bubble dripping” did.
Based on the average score of 10 people, those whose evaluations of 評価 and ○ were ensured according to the following criteria were judged to be dentifrice compositions that felt that bubbles would not easily sag from the mouth during brushing.
Evaluation criteria A: Average point 3.5 points or more and 4.0 points or less ○: Average point 3.0 points or more and less than 3.5 points Δ: Average point 2.0 points or more and less than 3.0 points ×: Average point 1. 0 points or more and less than 2.0 points

(2) Evaluation method of creamy feeling of foam during tooth brushing 10 panelists extrude the toothpaste composition filled in the laminate tube onto a commercial toothbrush by 1 cm, brush the teeth for 3 minutes, Compared to the control (a dentifrice composition having the same composition as in Example 1 except that it does not contain (A) a highly polymerized polyethylene glycol, (C) an amphoteric surfactant, and (D) a nonionic surfactant). , “Improved”, “Slightly improved”, “Slightly improved” and “Not improved” were obtained. Of these answers, “Improved” was determined as 4 points, “Slightly improved” as 3 points, “Slightly improved” as 2 points, and “Not improved” as 1 point.
Based on the average score of 10 people, those whose evaluations of ◎ and ○ were ensured according to the following criteria were judged to be a dentifrice composition that felt that the creamy feeling of the foam during brushing was improved.
Evaluation criteria A: Average point 3.5 points or more and 4.0 points or less ○: Average point 3.0 points or more and less than 3.5 points Δ: Average point 2.0 points or more and less than 3.0 points ×: Average point 1. 0 points or more and less than 2.0 points

(3) Evaluation method of flavor standing during toothbrushing 10 panelists extrude the toothpaste composition filled in the laminate tube 1cm onto a commercial toothbrush and brush the teeth for 3 minutes. Responses were obtained in four levels: “very good”, “good”, “somewhat bad”, and “bad”. Of these answers, “very good” was scored 4 points, “good” was scored 3 points, “somewhat bad” was scored 2 points, and “bad” was scored 1 point.
From the average score of 10 people, those that were evaluated as ◎ and ○ by the following criteria were judged to be a dentifrice composition with good flavor standing during toothpaste.
Evaluation criteria A: Average point 3.5 points or more and 4.0 points or less ○: Average point 3.0 points or more and less than 3.5 points Δ: Average point 2.0 points or more and less than 3.0 points ×: Average point 1. 0 points or more and less than 2.0 points

Details of the raw materials used are shown below. The viscosity of the highly polymerized polyethylene glycol is the viscosity at 25 ° C. measured with a Brookfield viscometer (Brookfield RVT or RVF), as described above. Moreover, the viscosity of 5 W / V% of polyethylene glycol 4000 measured by the same method was less than 10 mPa · s.
・ Highly polymerized polyethylene glycol;
POLYOX WSR N-80
(Viscosity of 5 W / V% aqueous solution manufactured by Dow Chemical Company: 85 mPa · s (rotor No. 1, rotation speed 50 rpm, measurement time 0.5 minutes))
POLYOX WSR N-10
(Manufactured by Dow Chemical Co., Ltd., viscosity of 5 W / V% aqueous solution: 35 mPa · s (rotor No. 1, rotation speed 50 rpm, measurement time 0.5 minutes))
POLYOX WSR N-750
(Dow Chemical Co., Viscosity of 5 W / V% aqueous solution: 1,100 mPa · s
(Rotor No. 2, rotation speed 10 rpm, measurement time 1 minute))
POLYOX WSR N-12K
(Manufactured by Dow Chemical Co., Ltd., viscosity of 2 W / V% aqueous solution: 420 mPa · s (rotor No. 1, rotation speed 10 rpm, measurement time 1 minute))
・ Polyethylene glycol 4000 (comparative component)
(Meanwhile, Sanyo Chemical Industries, Ltd.
600-3,800)
・ Sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd.)
・ Sodium myristyl sulfate (Nikko Chemicals)
Palm oil fatty acid amidopropyl betaine (TEGO BETAIN CK OK, manufactured by EVONIC)
・ 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolium betaine (Enazicol C-40H, manufactured by Lion Corporation)
Polyoxyethylene (40) hydrogenated castor oil (ethylene oxide average addition mole number 40, EMALEX HC-40,
Made by Nippon Emulsion Co.)
Polyoxyethylene (20) hydrogenated castor oil (ethylene oxide average addition mole number 20, EMALEX HC-20,
Made by Nippon Emulsion Co.)
Details of the compositions of the perfumes A-1 to A-3, B-1, B-2, and C are as shown in Tables 5 to 11 described later.

Table 4 below shows formulation examples. All of these toothpaste compositions were difficult to drip, excellent in creamy feeling, and good in flavor.

*: Parts by mass, and so on.

Claims

(A) Highly polymerized polyethylene glycol, (B) alkyl sulfate, (C) amphoteric surfactant and (D) nonionic surfactant are contained, and (C) component / (D) component has a mass ratio of 0. A toothpaste composition characterized by having 5 to 5.
The highly polymerized polyethylene glycol as component (A) has a viscosity of 10 mPa · s or more at 25 ° C. measured at 25 ° C. measured with a Brookfield viscometer and 2 W / V at 25 ° C. measured with the viscometer. The toothpaste composition according to claim 1, wherein the viscosity of the% aqueous solution is 800 mPa · s or less.
The toothpaste composition according to claim 1 or 2, wherein the component (C) is a betaine amphoteric surfactant.
4. The toothpaste composition according to claim 1, wherein the betaine amphoteric surfactant of component (C) is fatty acid amidopropyl betaine and / or 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolium betaine. object.
The toothpaste composition according to any one of claims 1 to 4, wherein the component (D) is polyoxyethylene hydrogenated castor oil having an average addition mole number of ethylene oxide of 20 to 40.
Component (A) is 0.05 to 0.5% by mass, Component (B) is 1 to 3.5% by mass, Component (C) is 0.05 to 1% by mass, Component (D) is 0.1 to The toothpaste composition according to any one of claims 1 to 5, containing 3% by mass.
The toothpaste composition according to any one of claims 1 to 6, further comprising (E) 0.5 to 2.5% by mass of a fragrance.
(C) Amphoteric surfactant and (D) Nonionic surfactant, (C) Component / (D) component, in a toothpaste composition containing (A) highly polymerized polyethylene glycol and (B) alkyl sulfate Is blended in a mass ratio in the range of 0.05 to 5, in the method of improving bubble sag by the combined use of the components (A) and (B) in the toothpaste composition.
The highly polymerized polyethylene glycol as component (A) has a viscosity of 10 mPa · s or more at 25 ° C. measured at 25 ° C. measured with a Brookfield viscometer and 2 W / V at 25 ° C. measured with the viscometer. The method of improving bubble sag by the combined use of the components (A) and (B) in the toothpaste composition according to claim 8, wherein the viscosity of the% aqueous solution is 800 mPa · s or less.
Component (A) is 0.05 to 0.5% by mass, Component (B) is 1 to 3.5% by mass, Component (C) is 0.05 to 1% by mass, Component (D) is 0.1 to A method for improving bubble sag by combining the components (A) and (B) in the toothpaste composition according to claim 8 or 9, wherein 3% by mass is blended.
Furthermore, (E) The method for improving bubble sag by combining the components (A) and (B) in the toothpaste composition according to claim 8, 9 or 10 containing 0.5 to 2.5% by mass of a fragrance.