JP5845867B2 - Dentifrice composition - Google Patents

Description

  The present invention relates to a dentifrice composition having improved foam feel, particularly giving a soft feel foam when brushing teeth, and excellent in mixed skin and liquid separation stability at low temperature storage.

  Of the feeling of use of the dentifrice composition, the feeling of foam in the oral cavity is one of the textures that can feel a cleaning feeling. In recent years, products characterized by the feeling of foam during tooth brushing, such as skin care products and hair care products, have been put on the market, and consumers are also paying attention to foam when brushing teeth. Such foam feel is thought to lead to satisfaction that the teeth have been gently brushed, and improving the feel of foam when brushing teeth is effective for improving consumer preference and more foam There is a need for a dentifrice composition that feels good.

  On the other hand, with regard to the foam performance of the dentifrice composition, the applicant applied a dentifrice composition containing polyvinylpyrrolidone, fatty acid diethanolamide or polyoxyethylene hydrogenated castor oil, and alkyl sulfate in order to retain the foam during brushing for a long time in the oral cavity. A dentifrice composition (see Patent Document 2) using a combination of a product (see Patent Document 1), xanthan gum, polyvinylpyrrolidone, sorbit, alkyl sulfate, and titanium oxide. Moreover, the dentifrice composition which improved the creamy feeling of the foam by using together the specific highly polymerized polyethylene glycol, alkyl sulfate, thickening silica, and / or aluminum silicate type thickening component was proposed (patent document 3). reference). However, it is difficult to say that the softness of the foam can be realized among the various feels of the foam, and there is still room for improvement in the foam feel.

JP 11-209255 A JP 2009-149540 A International Publication No. 2010/073975 Pamphlet JP 2006-347987 A JP 2011-132137 A Japanese Patent Laid-Open No. 10-291921 Japanese Patent Laid-Open No. 10-87460

  As described above, in the dentifrice composition, it is desired to improve the feeling of use by providing a foam that can give a feeling of gently brushing the teeth. However, in the prior art, the softness of the foam during brushing is desired. It was difficult to give a bubble feel that can be felt. Therefore, improvement of the foam feel has been a problem.

  The present invention has been made to solve the above-mentioned problems, and has an object to provide a dentifrice composition having improved foam feel, giving a soft feel foam when brushing teeth, and having excellent low-temperature storage stability. To do.

  As a result of intensive studies to achieve the above object, the present inventor has (A) alkyl sulfate, (B) sodium carboxymethylcellulose, (C) polyoxyethylene hydrogenated castor oil, (D) N- It has been found that blending with acyl-L-glutamate in combination improves the foam feel when brushing teeth, gives a soft feel foam, and is excellent in low-temperature storage stability. Invented the invention.

  That is, when the components (A), (B) and (C) are used in combination, the low-temperature storage stability can be improved, but there is a problem that the foam is inferior, but the component (D) is added to the combination system. As a result, the above-mentioned problems can be solved unexpectedly, the foam feel can be improved, a foam with a soft feel can be obtained when brushing teeth, and the skin and liquid separation stability during low-temperature storage are also improved. In the present invention, by combining the components (A), (B), (C) and (D), the above-mentioned special effects can be achieved. When the component (A) or (B) is lacking, It is inferior in softness and has low low-temperature storage stability. When component (C) is lacking, it is inferior in low-temperature storage stability. When component (D) is lacking, it is inferior in foam softness. The object of the invention cannot be achieved.

  Patent Documents 4 and 5 describe that an improvement effect of foaming amount and foam persistence is recognized in a dentifrice composition containing lauryl sulfate, sodium carboxymethylcellulose, and polyoxyethylene hydrogenated castor oil. Moreover, the technique which mix | blended N-acyl-L-glutamate and improved foamability and foaming property (refer patent document 6), the technology which improved the foaming property and foam retention property of non-aerosol type foamed toothpaste products ( Patent Document 7) has been proposed. However, from these techniques, it is difficult to predict the improvement of the foam feel and the low-temperature storage stability due to the combined use of the components (A), (B), (C) and (D).

Therefore, the present invention
(A) 0.8 to 2.5% by mass of alkyl sulfate, (B) 0.6 to 2.5% by mass of sodium carboxymethylcellulose, and (C) the average added mole number of ethylene oxide is 5 to 40 mol. 0.05 to 3% by mass of a certain polyoxyethylene hydrogenated castor oil, and (D) 0.3 to 2% by mass of N-acyl-L-glutamate whose acyl group has 8 to 20 carbon atoms A dentifrice composition is provided.

  The dentifrice composition of the present invention has improved foam feel, gives a soft feel foam when brushing, and is excellent in low-temperature storage stability.

  Hereinafter, the present invention will be described in more detail. The dentifrice composition of the present invention is suitably prepared as a dentifrice such as a toothpaste, a liquid dentifrice, and a toothpaste, particularly a toothpaste, and includes (A) an alkyl sulfate, (A) an alkyl sulfate, ( B) Sodium carboxymethylcellulose, (C) polyoxyethylene hydrogenated castor oil, and (D) N-acyl-L-glutamate are blended as essential components.

  (A) Alkyl sulfates having 8 to 18, particularly 12 to 14 carbon atoms in the alkyl group are suitable, and alkali metal salts such as sodium salts and potassium salts are used. If the alkyl group has less than 8 carbon atoms, irritation may be felt at the time of use, and the taste may deteriorate, and if it exceeds 18, foaming may be deteriorated.

Specific examples of the alkyl sulfate include potassium lauryl sulfate, sodium lauryl sulfate, triethanolamine lauryl sulfate, sodium myristyl sulfate, and sodium cetyl sulfate. Among these, sodium lauryl sulfate is preferable from the viewpoints of solubility and usability.
In addition, the alkyl sulfate can use a commercial item, for example, sodium lauryl sulfate can use the product made by Toho Chemical Industry Co., Ltd., Nikko Chemicals Co., Ltd., etc.

  The blending amount of the alkyl sulfate is preferably 0.8 to 2.5% (mass%, the same shall apply hereinafter) of the total composition, and more preferably 1.0 to 2.0%. In particular, since the foam feeling can be further improved by the appropriate amount of foam, it is more preferably 1.2 to 1.8%. If the blending amount is less than 0.8%, the foam may be inferior in softness. When it exceeds 2.5%, the softness of the foam and the low-temperature storage stability may be inferior. In addition, the feeling of use may worsen, such as irritation in the oral cavity.

  As (B) sodium carboxymethylcellulose, those having a viscosity of a 2% aqueous solution at 25 ° C. of 300 to 1,500 mPa · s, particularly 340 to 1,050 mPa · s, are suitable. If the viscosity of the 2% aqueous solution is less than 300 mPa · s, the foam may be inferior in softness. If it exceeds 1,500 mPa · s, dispersibility in the oral cavity may be deteriorated, and foam feel may be deteriorated.

The viscosity of sodium carboxymethylcellulose is a value measured with a BH viscometer by the following method.
In a 300 ml beaker, 20 g of propylene glycol was added, and 6.0 g of sodium carboxymethylcellulose was added thereto and well dispersed. Next, 274 g of purified water was added to the dispersion, and the mixture was stirred in a constant temperature water bath at 25 ° C. using a stirrer with three blades (manufactured by Shinto Kagaku Co., Ltd., BL1200). After 1 minute of stirring, the viscosity was measured using a viscometer (manufactured by Tokyo Keiki Co., Ltd., B8H type viscometer, rotor No. 2, rotation speed 20 rpm, measurement time 3 minutes later).

  A commercial item can be used as sodium carboxymethylcellulose. Examples thereof include CMC Daicel manufactured by Daicel Finechem Co., Ltd. and Sunrose manufactured by Nippon Paper Chemicals Co., Ltd.

  The amount of sodium carboxymethylcellulose is preferably 0.6 to 2.5% of the total composition, more preferably 0.7 to 2.0%. In particular, 0.8 to 1.6% is more preferable from the viewpoint of softness of foam and liquid separation stability. If the blending amount is less than 0.6%, sufficient foam softness may not be obtained. Moreover, it may be inferior to low-temperature storage stability. If it exceeds 2.5%, the softness of the foam and the skin after cold storage may be inferior.

In the present invention, it is important for formulating the effects of the present invention that the (C) component is combined with the (A) and (B) components.
(C) As the polyoxyethylene hydrogenated castor oil, an average added mole number of ethylene oxide (EO) is preferably 40 mol or less in view of softness of foam, particularly 5 to 40 mol, especially 20 to 20 mol. A 40-mol thing can be used more suitably. When the average added mole number of ethylene oxide exceeds 40 moles, the foam may be inferior. If it is less than 5 moles, the stability during low-temperature storage is inferior, and a peculiar taste may occur, resulting in a poor taste of the preparation.

  Polyoxyethylene hydrogenated castor oil may be used alone or in combination of two or more. Moreover, what is marketed can be used, and as such polyoxyethylene hydrogenated castor oil, for example, HCO-10, HCO-20, HCO-30, HCO-40, Nihon Emulsion (manufactured by Nikko Chemicals Co., Ltd.) HC-5, HC-10, HC-20, HC-30, HC-40 manufactured by Co., Ltd., BLAUNON CW-10, CW-25 manufactured by Aoki Oil & Fat Co., Ltd., and the like.

  The blending amount of the polyoxyethylene hydrogenated castor oil is preferably 0.05 to 3%, particularly preferably 0.1 to 1% of the entire composition. In particular, the content is more preferably 0.2 to 1% from the viewpoint of softness of foam and liquid separation stability. If the blending amount is less than 0.05%, the liquid separation stability after low-temperature storage may be poor, and if it exceeds 3%, the softness of the foam may be deteriorated.

(D) Component N-acyl-L-glutamate is a foam feel-improving agent.
As the N-acyl-L-glutamate, an acyl group having 8 to 20 carbon atoms, particularly 12 to 16 carbon atoms is preferable. Examples of the salt include alkali metal salts such as sodium and potassium, alkaline earth metal salts, and organic amine salts.
Specific examples include sodium N-lauroyl-L-glutamate, N-lauroyl-L-glutamic acid triethanolamine, and N-myristoyl-L-glutamic acid sodium. Of these, sodium N-lauroyl-L-glutamate is more preferable from the viewpoint of usability.
In addition, a commercial item can be used for N-acyl-L-glutamate, for example, N-lauroyl-L-glutamate sodium can use the product made from Ajinomoto Co., Inc., Asahi Kasei Chemicals Co., Ltd., etc.

  The blending amount of N-acyl-L-glutamate is preferably 0.3 to 2% of the total composition, more preferably 0.5 to 1.5%. In particular, it is more preferably 0.5 to 1.2% from the viewpoint of softness of foam and low-temperature storage stability. If the blending amount is less than 0.3%, the foam may be inferior in softness. If it exceeds 2%, the low-temperature storage stability may be inferior.

  In the dentifrice composition of the present invention, in addition to the above-described components, other known components that are usually used in dentifrice compositions can be blended as necessary within a range not impairing the effects of the present invention. Optional ingredients that can be blended include abrasives, binders, surfactants, wetting agents, sweeteners, fragrances, pH adjusters, preservatives, active ingredients or medicinal ingredients.

  Examples of abrasives include dicalcium phosphate dihydrate and anhydrous salts, calcium phosphate compounds such as primary calcium phosphate, tertiary calcium phosphate, and calcium pyrophosphate, silica-based abrasives such as precipitated silica and aluminosilicate, calcium carbonate, Calcium hydroxide, aluminum hydroxide, tribasic magnesium phosphate, magnesium carbonate, calcium sulfate, bentonite, etc., or granulated products of these components can be mentioned, and one or more of these can be blended. The blending amount of the abrasive is usually preferably 0 to 60%, particularly preferably 8 to 50% of the entire composition.

Examples of the binder include (B) inorganic binders other than sodium carboxymethyl cellulose, such as thickening silica and aluminum silicate, xanthan gum, polyvinyl pyrrolidone, carrageenan, methyl cellulose, sodium hydroxyethyl cellulose, sodium alginate, tragacanth gum, karaya gum Organic binders such as arabic gum, locust bean gum, polyvinyl alcohol, sodium polyacrylate, cross-linked sodium polyacrylate, carboxyvinyl polymer, carbopol, bee gum, propylene glycol alginate and the like may be blended.
These binders do not need to be blended, but when added, a range that does not interfere with the effects of the present invention and a total of 0.6 to 10% of the total composition with the component (B) is desirable.

As the surfactant, known surfactants other than the components (A), (C), and (D), for example, anionic surfactants, cationic surfactants, and nonionic surfactants may be used alone. Or it can mix | blend in combination of 2 or more types.
Examples of anionic surfactants include N-acyl tau such as sodium dodecylbenzenesulfonate, hydrogenated coconut fatty acid monoglyceride sodium monosulfate, sodium lauryl sulfoacetate, sodium α-olefin sulfonate, and sodium N-methyl-N-acyl taurate. Rate, acyl sarcosine sodium and the like.
Examples of the cationic surfactant include alkyl ammonium and alkyl benzyl ammonium salts.
Nonionic surfactants include polyglycerin fatty acid esters, sucrose fatty acid esters, sucrose fatty acid esters such as maltose fatty acid esters, sugar alcohol fatty acid esters such as maltitol fatty acid esters and lactol fatty acid esters, alkylol amides, polyoxy Polyoxyethylene sorbitan fatty acid ester such as ethylene sorbitan monostearate, fatty acid diethanolamide such as lauric acid mono or diethanolamide, sorbitan fatty acid ester, polyoxyethylene higher alcohol ether, polyoxyethylene polyoxypropylene copolymer, polyoxyethylene Examples include polyoxypropylene fatty acid esters and pluronics.
The blending amount of these surfactants is preferably in a range where the total amount including the components (A), (C), and (D) is 10% or less, particularly 1.5 to 8% of the entire composition.

  Examples of the wetting agent include sorbitol, glycerin, propylene glycol, polyethylene glycol having an average molecular weight of 200 to 6,000, ethylene glycol, 1,3-butylene glycol, erythritol, reduced starch saccharified polyhydric alcohol, sugar alcohol One kind can be blended alone or in combination of two or more kinds. The blending amount is preferably 28 to 50% of the entire composition.

  Examples of the sweetening agent include saccharin sodium, stevioside, stevia extract, paramethoxycinnamic aldehyde, neohesperidyl hydrochalcone, perlartin, glycyrrhizin, thaumatin, asparatylphenylalanine methyl ester and the like. The compounding quantity of a sweetener is 0.01 to 5% of the whole composition normally.

As the fragrance, known fragrances such as menthol, anethole, carvone, eugenol, limonene, n-decyl alcohol, citronellol, α-terpineol, citronellyl acetate, cineol, linalool, ethyl linalool, vanillin, thymol, spearmint oil, peppermint oil , Lemon oil, orange oil, sage oil, rosemary oil, cinnamon oil, pimento oil, cinnamon leaf oil, perilla oil, winter green oil, clove oil, eucalyptus oil and the like. The compounding quantity of the fragrance | flavor in a composition can be 0.001-2%.
Examples of the pH adjuster include organic acids such as citric acid and lactic acid and salts thereof, and inorganic compounds such as hydrochloric acid, sodium hydroxide, potassium hydroxide, disodium hydrogen phosphate, and sodium dihydrogen phosphate.
Examples of the preservative include paraoxybenzoic acid ester and sodium benzoate.

  Medicinal or active ingredients include enzymes such as dextranase, amylase, protease, mutanase, tranexamic acid, epsilon aminocaproic acid, aluminum chlorohydroxy allantoin, azulene, glycyrrhizinate, glycyrrhetinate, sodium chloride, vitamins, etc. Anti-inflammatory agents, isopropylmethylphenol, copper chlorophyll, copper gluconate, cetylpyridinium chloride, benzalkonium chloride, hinokitiol, lysozyme chloride and other antibacterial agents, pyrophosphates, polyphosphates and calculus preventives such as zeolite, vitamin E Blood circulation promoters such as amino acids such as glycine and proline. In addition, the compounding quantity of a medicinal ingredient or an active ingredient can be made into an effective quantity in the range which does not prevent the effect of this invention.

  In addition, as optional components, inorganic compounds such as hydroxyapatite, mica titanium, titanium oxide, bentonite and the like, granules of cellulose organic powder such as crystalline cellulose, agar, gelatin, starch, gluco Natural polymer compounds such as mannan, synthetic polymer compounds such as polyvinyl acetate, acrylic, polyurethane, polyester, polyvinyl chloride, nylon powder, polyethylene powder and their copolymers, carnauba wax, rosin, rice wax, microcrystalline Wax, beeswax, waxes such as paraffin wax, higher alcohols such as cetanol and stearyl alcohol, latex rubbers such as polyisobutylene, polybutadiene, urethane, silicone, natural rubber, etc. There may be used or lame film those obtained by mixing these materials. Lame films include organic resin laminated film powder, laminated film powder in which a vapor deposition layer such as aluminum is introduced into the organic resin laminated film, specifically, polyethylene terephthalate / polymethyl methacrylate laminated film powder, polyethylene terephthalate -Aluminum-epoxy laminated powder etc. can be mix | blended in the range which does not prevent the effect of this invention.

  EXAMPLES Hereinafter, although an Example and a comparative example are shown and this invention is demonstrated concretely, this invention is not restrict | limited to the following Example. In the following examples,% is mass% unless otherwise specified. Moreover, the sorbitol used the 70% solution, and the compounding quantity in the table | surface shown below was shown by the amount of solid.

[Examples and Comparative Examples]
Dentifrice compositions (toothpaste) shown in Tables 1 and 2 were prepared by the following production method. The resulting toothpaste composition was evaluated for foam feeling (softness of foam) and storage stability at low temperatures by the following methods. The results are shown in the table.

Manufacturing method of dentifrice composition:
(1) A water-soluble component containing sorbit was mixed and dissolved at room temperature in purified water (phase A).
(2) Phase B, in which sodium carboxymethylcellulose was dispersed at room temperature in propylene glycol, was added and mixed into Phase A under stirring to prepare Phase C.
(3) A fragrance, an abrasive, and a surfactant were mixed in the C phase at room temperature using a kneader (manufactured by Ishiyama Works), and defoamed under reduced pressure (5.3 kPa) to obtain a dentifrice composition.

<Foam feeling (softness of foam)>
Evaluation was conducted by a sensory test using 10 professional panelists. The test dentifrice composition filled in a laminated tube having a diameter of 8 mm was placed on a toothbrush by about 1.5 cm and used for 3 minutes by a method of brushing normal teeth, and the softness of the foam was subjected to sensory evaluation according to the following evaluation criteria-1. Judgment was made according to Evaluation Criteria-2 from the average score of the results of 10 people.
Here, as for the softness of the foam, a soft foam was judged that the user felt that the foam was soft when brushing his teeth and that his teeth were gently brushed.
Evaluation criteria-1
5 points: Foam felt very soft 4 points: Foam felt very soft 3 points: Foam felt soft 2 points: Neither of them 1 point: Foam did not feel soft (Criteria for the average value of the evaluation results of 10 panelists)
◎: Average point is 4.0 points or more and 5.0 points or less ○: Average point is 3.0 points or more and less than 4.0 points △: Average point is 2.0 points or more and less than 3.0 points ×: Average point is Less than 2.0

<Low temperature storage stability (shrinked skin, liquid separation)>
The low-temperature storage stability was evaluated as follows. The test dentifrice composition filled in an 8 mm diameter laminated tube was stored for 4 weeks in a thermostatic bath controlled at a temperature cycle of −5 ° C. and 10 ° C. The temperature cycle was repeatedly increased from −5 ° C. to 10 ° C. in 24 hours, and when it reached 10 ° C., the temperature cycle was similarly decreased in 24 hours. The test dentifrice composition taken out from the thermostatic bath is returned to room temperature, and then extruded on a straw half paper so that a total of three pieces are about 10 cm. The skin of the kneading at that time was evaluated visually. Evaluation was according to Evaluation Criteria-3. Further, the amount of the liquid soaked on the back of the straw half paper was regarded as the degree of liquid separation, and evaluation was performed according to Evaluation Criteria-4.
Evaluation Criteria-3 (Condensed skin when kneaded and spread on straw half paper)
A: Glossy and very smooth B: Glossy and smooth △: Small irregularities or roughness observed x: Evaluation criterion -4 (larger irregularities and / or lumps and grains recognized) Separation)
◎: The liquid does not ooze out ○: About 0.5 cm, the liquid oozes out △: About 0.5-1.5 cm, the liquid ooze out ×: The liquid oozes out over 1.5 cm Have

The raw materials used in the following examples are as follows.
Sodium lauryl sulfate; sodium lauryl sulfate, sodium carboxymethyl cellulose manufactured by Toho Chemical Industry Co., Ltd .;
CMC1260, manufactured by Daicel Chemical Industries, Ltd. (2% aqueous solution viscosity: 918 mPa · s)
N-lauroyl-sodium L-glutamate;
Amino Surfact ALMS, polyoxyethylene hydrogenated castor oil-1 manufactured by Asahi Kasei Chemicals Corporation;
HCO-20 (EO, average added mole number 20), polyoxyethylene hydrogenated castor oil-2 manufactured by Nikko Chemicals Co., Ltd .;
HCO-10 (EO, average added mole number 10), polyoxyethylene hydrogenated castor oil-3 manufactured by Nikko Chemicals Co., Ltd .;
HCO-40 (EO, average added mole number 40), manufactured by Nikko Chemicals Co., Ltd. The fragrance composition is as shown in Tables 3-6.

The viscosity of a 2% aqueous solution of sodium carboxymethylcellulose was measured by the following method.
<Viscosity measurement method of sodium carboxymethyl cellulose>
In a 300 ml beaker, 20 g of propylene glycol was added, and 6.0 g of sodium carboxymethylcellulose was added thereto and well dispersed. Next, 274 g of purified water was added to the dispersion, and the mixture was stirred in a constant temperature water bath at 25 ° C. using a stirrer with three blades (manufactured by Shinto Kagaku Co., Ltd., BL1200). After 1 minute of stirring, the viscosity was measured using a viscometer (manufactured by Tokyo Keiki Co., Ltd., B8H type viscometer, rotor No. 2, rotation speed 20 rpm, measurement time 3 minutes later).

表中、部はいずれも質量部である（以下、同様。）。

In the table, all parts are parts by mass (the same applies hereinafter).

As can be seen from the results in Tables 1 and 2, when (A) sodium lauryl sulfate is not included, excellent softness of foam is obtained even if the components (B), (C) and (D) are contained. And liquid separation after low-temperature storage was inferior (Comparative Example 1). (B) When sodium carboxymethylcellulose is not included, even if the components (A), (C), and (D) are contained, excellent foam softness cannot be obtained, and liquid separation after low-temperature storage (Comparative Example 2). Even if it contained the components (A), (B) and (D), it did not have good wet skin and liquid separation after low-temperature storage unless it contained (C) polyoxyethylene hydrogenated castor oil (Comparative Example 4). Moreover, even if it contained (A), (B) and (C) component, when it did not contain (D) sodium N-acyl L-glutamate, the softness of the excellent foam was not obtained (comparison) Example 3). Thus, in the comparative example, it was not possible to obtain a preparation excellent in all of the softness of foam, the skin after low-temperature storage and liquid separation.
On the other hand, by using the components (A), (B), and (C) in combination and blending the component (D), the dentifrice composition is excellent in softness of foam and excellent in low-temperature storage stability. It was found that the object of the present invention can be achieved.

  Moreover, the dentifrice composition shown below was manufactured using the same raw material, and evaluated similarly. These were confirmed to have excellent foam softness and excellent storage stability at low temperatures.

[Example 14] Toothpaste (A) Sodium lauryl sulfate 1.2
(B) Sodium carboxymethylcellulose 1.5
(2% aqueous solution viscosity; 509 mPa · s)
(C) Polyoxyethylene hydrogenated castor oil-1 1
(EO average added mole number; 20)
(D) Sodium N-lauroyl-L-glutamate 0.5
Propylene glycol 3
Sorbit liquid (70%) 25
Sodium monofluorophosphate 0.7
Heavy calcium carbonate 30
Fragrance-2 1
Saccharin sodium 0.15
Water balance
Total 100%

[Example 15] Toothpaste (A) Sodium lauryl sulfate 0.8
(B) Sodium carboxymethylcellulose 1.4
(2% aqueous solution viscosity: 345 mPa · s)
(C) Polyoxyethylene hydrogenated castor oil-1 0.5
(EO average added mole number; 20)
(D) Sodium N-lauroyl-L-glutamate 1.2
Propylene glycol 3
Sorbit liquid (70%) 30
Sodium monofluorophosphate 0.7
Thickening silica 4
Sodium hydrogen phosphate 20
Fragrance-1 1
Saccharin sodium 0.15
Water balance
Total 100%

Toothpaste [Example 16]
(A) Sodium lauryl sulfate 1.5
(B) Sodium carboxymethylcellulose 0.9
(2% aqueous solution viscosity; 1,046 mPa · s)
(B) Sodium carboxymethylcellulose 0.3
(2% aqueous solution viscosity; 353 mPa · s)
(C) Polyoxyethylene hydrogenated castor oil-2 3.0
(EO average added mole number; 10)
(D) Sodium N-lauroyl-L-glutamate 0.5
Propylene glycol 3
Sorbit liquid (70%) 40
Sodium fluoride 0.2
Abrasive silica 15
Fragrance-2 1
Saccharin sodium 0.15
Water balance
Total 100%

Claims (6)

(A) 0.8 to 2.5% by mass of alkyl sulfate, (B) 0.6 to 2.5% by mass of sodium carboxymethylcellulose, and (C) the average added mole number of ethylene oxide is 5 to 40 mol. 0.05 to 3% by mass of a certain polyoxyethylene hydrogenated castor oil, and (D) 0.3 to 2% by mass of N-acyl-L-glutamate whose acyl group has 8 to 20 carbon atoms A dentifrice composition characterized by comprising: The dentifrice composition of Claim 1 whose content of (D) component is 0.4-1.5 mass%.   The dentifrice composition according to claim 1 or 2, wherein the component (A) is sodium lauryl sulfate. The component (D) is an N-acyl-L-glutamate selected from sodium N-lauroyl-L-glutamate, N-lauroyl-L-glutamate triethanolamine, and N-myristoyl-L-glutamate sodium. Or the dentifrice composition of 2 description. The dentifrice composition according to any one of claims 1 to 4, wherein the component (D) is N-lauroyl-L-glutamate. The dentifrice composition according to any one of claims 1 to 5, which is prepared as a toothpaste composition.