WO2012081898A3 - 위암의 예후 예측용 마커 및 이를 이용하는 위암의 예후 예측 방법 - Google Patents
위암의 예후 예측용 마커 및 이를 이용하는 위암의 예후 예측 방법 Download PDFInfo
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- WO2012081898A3 WO2012081898A3 PCT/KR2011/009603 KR2011009603W WO2012081898A3 WO 2012081898 A3 WO2012081898 A3 WO 2012081898A3 KR 2011009603 W KR2011009603 W KR 2011009603W WO 2012081898 A3 WO2012081898 A3 WO 2012081898A3
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- stomach cancer
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57446—Specifically defined cancers of stomach or intestine
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- G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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Abstract
본 발명은 위암의 예후를 예측하기 위한 마커, 이의 발현수준을 측정하는 제제를 포함하는 위암의 예후 예측용 조성물 및 키트, 및 상기 마커를 이용하여 위암의 예후를 예측하는 방법에 관한 것이다. 본 발명에 의하면, 위암의 예후를 신속하고 정확하게 예측하고, 예측된 예후에 따른 적절한 치료방향을 결정할 수 있어 위암으로 인한 사망률의 감소에 크게 기여할 수 있는 이점이 있다. 특히, 본 발명에 의하여 병기 Ib/II기 위암 환자 중 음성적 예후를 가질 것이라고 예측된 환자에 대하여 병기 III기 위암 환자를 대상으로 시술되는 치료방법을 사용함으로써 생존율 증가에 크게 기여할 수 있을 것이다.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL11849123T PL2653546T3 (pl) | 2010-12-13 | 2011-12-13 | Marker do ustalenia rokowania raka żołądka i sposób ustalenia rokowania raka żołądka |
EP11849123.2A EP2653546B1 (en) | 2010-12-13 | 2011-12-13 | Marker for predicting stomach cancer prognosis and method for predicting stomach cancer prognosis |
US13/994,072 US9315869B2 (en) | 2010-12-13 | 2011-12-13 | Marker for predicting gastric cancer prognosis and method for predicting gastric cancer prognosis using the same |
ES11849123.2T ES2689958T3 (es) | 2010-12-13 | 2011-12-13 | Marcador para predecir el pronóstico de cáncer de estómago y procedimiento para predecir el pronóstico de cáncer de estómago |
CN201180065578.XA CN103459597B (zh) | 2010-12-13 | 2011-12-13 | 用于预测胃癌预后的标记和使用该标记预测胃癌预后的方法 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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KR10-2010-0127197 | 2010-12-13 | ||
KR20100127197 | 2010-12-13 | ||
US201161432542P | 2011-01-13 | 2011-01-13 | |
US61/432,542 | 2011-01-13 |
Publications (2)
Publication Number | Publication Date |
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WO2012081898A2 WO2012081898A2 (ko) | 2012-06-21 |
WO2012081898A3 true WO2012081898A3 (ko) | 2012-10-11 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/KR2011/009603 WO2012081898A2 (ko) | 2010-12-13 | 2011-12-13 | 위암의 예후 예측용 마커 및 이를 이용하는 위암의 예후 예측 방법 |
Country Status (7)
Country | Link |
---|---|
US (1) | US9315869B2 (ko) |
EP (1) | EP2653546B1 (ko) |
KR (1) | KR101437718B1 (ko) |
CN (1) | CN103459597B (ko) |
ES (1) | ES2689958T3 (ko) |
PL (1) | PL2653546T3 (ko) |
WO (1) | WO2012081898A2 (ko) |
Families Citing this family (46)
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CA2870835C (en) * | 2012-04-19 | 2020-06-16 | Hon Sing LEONG | Method for detecting or monitoring prostate cancer |
KR101504818B1 (ko) * | 2013-04-05 | 2015-03-24 | 연세대학교 산학협력단 | 위암에 대한 예후 예측 시스템 |
KR101504817B1 (ko) * | 2013-04-05 | 2015-03-24 | 연세대학교 산학협력단 | 국소 진행형 위암에 대한 예후 예측 시스템 |
KR101501826B1 (ko) * | 2013-04-05 | 2015-03-13 | 연세대학교 산학협력단 | 위암에 대한 예후 예측 모형의 제조방법 |
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2011
- 2011-12-13 US US13/994,072 patent/US9315869B2/en not_active Expired - Fee Related
- 2011-12-13 EP EP11849123.2A patent/EP2653546B1/en active Active
- 2011-12-13 KR KR1020110134066A patent/KR101437718B1/ko active IP Right Grant
- 2011-12-13 PL PL11849123T patent/PL2653546T3/pl unknown
- 2011-12-13 WO PCT/KR2011/009603 patent/WO2012081898A2/ko active Application Filing
- 2011-12-13 ES ES11849123.2T patent/ES2689958T3/es active Active
- 2011-12-13 CN CN201180065578.XA patent/CN103459597B/zh active Active
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Also Published As
Publication number | Publication date |
---|---|
ES2689958T3 (es) | 2018-11-16 |
CN103459597B (zh) | 2016-03-30 |
EP2653546A4 (en) | 2016-11-09 |
EP2653546A2 (en) | 2013-10-23 |
US9315869B2 (en) | 2016-04-19 |
US20130337449A1 (en) | 2013-12-19 |
KR101437718B1 (ko) | 2014-09-11 |
KR20120065959A (ko) | 2012-06-21 |
EP2653546B1 (en) | 2018-08-08 |
PL2653546T3 (pl) | 2019-06-28 |
WO2012081898A2 (ko) | 2012-06-21 |
CN103459597A (zh) | 2013-12-18 |
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