WO2008099778A1 - スリット走査共焦点顕微鏡 - Google Patents
スリット走査共焦点顕微鏡 Download PDFInfo
- Publication number
- WO2008099778A1 WO2008099778A1 PCT/JP2008/052123 JP2008052123W WO2008099778A1 WO 2008099778 A1 WO2008099778 A1 WO 2008099778A1 JP 2008052123 W JP2008052123 W JP 2008052123W WO 2008099778 A1 WO2008099778 A1 WO 2008099778A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- slit
- light source
- confocal microscope
- scanning confocal
- light
- Prior art date
Links
- 238000003384 imaging method Methods 0.000 abstract 3
- 230000003287 optical effect Effects 0.000 abstract 2
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
Abstract
スリット走査共焦点顕微鏡は、スリット状の光源1と、光源1の像を試料3の上に結像させる照明光学系2と、試料3からの反射光、透過光又は蛍光を、光源1と光学的に共役な位置に配置された1次元撮像素子5上に結像させる結像光学系4とを有する。スリット状の光源1は、1次元撮像素子5の画素と光学的に共役な大きさの単位光源に分割されている。
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08711002A EP2124085A4 (en) | 2007-02-14 | 2008-02-08 | CONFOCAL SLOTTED SCANNING MICROSCOPE |
JP2008558072A JPWO2008099778A1 (ja) | 2007-02-14 | 2008-02-08 | スリット走査共焦点顕微鏡 |
US12/541,858 US20100202043A1 (en) | 2007-02-14 | 2009-08-14 | Slit-scanning confocal microscope |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007033397 | 2007-02-14 | ||
JP2007-033397 | 2007-02-14 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/541,858 Continuation US20100202043A1 (en) | 2007-02-14 | 2009-08-14 | Slit-scanning confocal microscope |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008099778A1 true WO2008099778A1 (ja) | 2008-08-21 |
Family
ID=39690011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/052123 WO2008099778A1 (ja) | 2007-02-14 | 2008-02-08 | スリット走査共焦点顕微鏡 |
Country Status (4)
Country | Link |
---|---|
US (1) | US20100202043A1 (ja) |
EP (1) | EP2124085A4 (ja) |
JP (1) | JPWO2008099778A1 (ja) |
WO (1) | WO2008099778A1 (ja) |
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JP6013337B2 (ja) | 2011-08-15 | 2016-10-25 | オリンパス株式会社 | 単一発光粒子検出を用いた光分析装置、光分析方法及び光分析用コンピュータプログラム |
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CN103765194B (zh) | 2011-08-30 | 2016-02-17 | 奥林巴斯株式会社 | 目标粒子的检测方法 |
JP6010035B2 (ja) | 2011-08-30 | 2016-10-19 | オリンパス株式会社 | 単一発光粒子検出を用いた光分析装置、光分析方法及び光分析用コンピュータプログラム |
JP5941923B2 (ja) | 2011-11-10 | 2016-06-29 | オリンパス株式会社 | 単一発光粒子検出を用いた光分析装置、光分析方法及び光分析用コンピュータプログラム |
CN104115001B (zh) | 2012-02-17 | 2016-08-24 | 奥林巴斯株式会社 | 利用单个粒子检测的光分析装置、光分析方法 |
JP5940644B2 (ja) | 2012-02-22 | 2016-06-29 | オリンパス株式会社 | 標的粒子の検出方法 |
WO2013140890A1 (ja) | 2012-03-21 | 2013-09-26 | オリンパス株式会社 | 標的核酸分子の検出方法 |
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JP6010114B2 (ja) | 2012-04-18 | 2016-10-19 | オリンパス株式会社 | 光分析を用いた単一粒子検出装置、単一粒子検出方法及び単一粒子検出用コンピュータプログラム |
FI125408B (fi) | 2012-09-17 | 2015-09-30 | Focalspec Oy | Menetelmä ja mittalaite pinnan etäisyyden, kohteen paksuuden ja optisten ominaisuuksien mittaamiseksi |
EP3029505A4 (en) | 2013-07-31 | 2017-03-15 | Olympus Corporation | Optical microscope device, microscopy method, and computer program for microscopy using single-light-emitting-particle detection technology |
JP6313776B2 (ja) | 2013-10-07 | 2018-04-18 | オリンパス株式会社 | 単一発光粒子検出を用いた光分析装置、光分析方法及び光分析用コンピュータプログラム |
WO2017098597A1 (ja) | 2015-12-09 | 2017-06-15 | オリンパス株式会社 | 単一発光粒子検出を用いた光分析方法及び光分析装置 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05188301A (ja) * | 1991-09-09 | 1993-07-30 | Sumitomo Electric Ind Ltd | レーザ顕微鏡 |
JP2004219537A (ja) * | 2003-01-10 | 2004-08-05 | Nikon Engineering Co Ltd | 共焦点顕微鏡 |
Family Cites Families (12)
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US5028802A (en) * | 1990-01-11 | 1991-07-02 | Eye Research Institute Of Retina Foundation | Imaging apparatus and methods utilizing scannable microlaser source |
US5107113A (en) * | 1990-12-26 | 1992-04-21 | Bell Communications Research, Inc. | Method and apparatus for correcting distortions in scanning tunneling microscope images |
US5563710A (en) * | 1994-10-28 | 1996-10-08 | The Schepens Eye Research Institute, Inc. | Imaging system with confocally self-detecting laser |
US6121603A (en) * | 1997-12-01 | 2000-09-19 | Hang; Zhijiang | Optical confocal device having a common light directing means |
US6399936B1 (en) * | 1997-12-01 | 2002-06-04 | New Dimension Research Instrument, Inc. | Optical confocal device having a common light directing means |
US6784982B1 (en) * | 1999-11-04 | 2004-08-31 | Regents Of The University Of Minnesota | Direct mapping of DNA chips to detector arrays |
US6987259B2 (en) * | 2002-05-30 | 2006-01-17 | Dmetrix, Inc. | Imaging system with an integrated source and detector array |
FR2849215B1 (fr) * | 2002-12-20 | 2005-03-11 | Mauna Kea Technologies | Systeme de microscopie laser confocale parallele basee sur la technologie vcsel |
DE102004016253B4 (de) * | 2004-04-02 | 2006-02-23 | Leica Microsystems Cms Gmbh | Rastermikroskop und Verfahren zur rastermikroskopischen Untersuchung einer Probe |
DE102004020663A1 (de) * | 2004-04-24 | 2005-11-10 | Carl Zeiss Meditec Ag | Einrichtung zur Beleuchtung organischer Objekte |
JP4894161B2 (ja) * | 2005-05-10 | 2012-03-14 | 株式会社ニコン | 共焦点顕微鏡 |
EP1996909A4 (en) * | 2006-03-09 | 2013-01-23 | Tessarae Llc | MICROARRAY IMAGING SYSTEM AND CORRESPONDING METHODS |
-
2008
- 2008-02-08 WO PCT/JP2008/052123 patent/WO2008099778A1/ja active Application Filing
- 2008-02-08 JP JP2008558072A patent/JPWO2008099778A1/ja active Pending
- 2008-02-08 EP EP08711002A patent/EP2124085A4/en not_active Withdrawn
-
2009
- 2009-08-14 US US12/541,858 patent/US20100202043A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05188301A (ja) * | 1991-09-09 | 1993-07-30 | Sumitomo Electric Ind Ltd | レーザ顕微鏡 |
JP2004219537A (ja) * | 2003-01-10 | 2004-08-05 | Nikon Engineering Co Ltd | 共焦点顕微鏡 |
Non-Patent Citations (2)
Title |
---|
See also references of EP2124085A4 * |
TADAO TSURUTA: "Light Pencil", NEW TECHNOLOGY COMMUNICATIONS, pages: 177 - 205 |
Also Published As
Publication number | Publication date |
---|---|
JPWO2008099778A1 (ja) | 2010-05-27 |
EP2124085A1 (en) | 2009-11-25 |
EP2124085A4 (en) | 2010-04-28 |
US20100202043A1 (en) | 2010-08-12 |
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