WO2008017752A3 - Extrait d ' eucalyptus, son procede de preparation et ses utilisations therapeutiques - Google Patents

Extrait d ' eucalyptus, son procede de preparation et ses utilisations therapeutiques Download PDF

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Publication number
WO2008017752A3
WO2008017752A3 PCT/FR2007/001309 FR2007001309W WO2008017752A3 WO 2008017752 A3 WO2008017752 A3 WO 2008017752A3 FR 2007001309 W FR2007001309 W FR 2007001309W WO 2008017752 A3 WO2008017752 A3 WO 2008017752A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
isobutyl
substituent
therapeutic uses
eucalyptus extract
Prior art date
Application number
PCT/FR2007/001309
Other languages
English (en)
Other versions
WO2008017752A2 (fr
Inventor
Christel Fiorini-Puybaret
Bernard Fabre
Cecile Chauvin
Philippe Joulia
Original Assignee
Pf Medicament
Christel Fiorini-Puybaret
Bernard Fabre
Cecile Chauvin
Philippe Joulia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA002659162A priority Critical patent/CA2659162A1/fr
Application filed by Pf Medicament, Christel Fiorini-Puybaret, Bernard Fabre, Cecile Chauvin, Philippe Joulia filed Critical Pf Medicament
Priority to JP2009522297A priority patent/JP2010500974A/ja
Priority to BRPI0714863-1A priority patent/BRPI0714863A2/pt
Priority to MX2009000673A priority patent/MX2009000673A/es
Priority to US12/309,754 priority patent/US20090324754A1/en
Priority to AU2007283529A priority patent/AU2007283529A1/en
Priority to NZ574429A priority patent/NZ574429A/en
Priority to EP07823364A priority patent/EP2049133A2/fr
Publication of WO2008017752A2 publication Critical patent/WO2008017752A2/fr
Publication of WO2008017752A3 publication Critical patent/WO2008017752A3/fr
Priority to TN2009000018A priority patent/TN2009000018A1/fr
Priority to IL196788A priority patent/IL196788A0/en
Priority to NO20090951A priority patent/NO20090951L/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/11Aldehydes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La présente invention concerne l'utilisation d'un extrait d'Eucalyptus pour la préparation d'un médicament ou d'un complément alimentaire destiné au traitement et/ou à la prévention des affections ou pathologies découlant d'un désordre de la recapture de neuromédiateurs. La présente invention concerne également un nouvel extrait enrichi d'Eucalyptus caractérisé en ce qu'il contient au moins 1 composé de formule (I) ou l'une quelconque de ses formes diastéréoisomères dans laquelle Rl forme avec le carbone auquel il est rattaché un groupement C=CH2, un groupement formule (II) et R2 re résente un rou ement isobut le,α-isobutyle ou β-isobutyle; ainsi que son procédé de préparation.
PCT/FR2007/001309 2006-08-01 2007-07-27 Extrait d ' eucalyptus, son procede de preparation et ses utilisations therapeutiques WO2008017752A2 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
AU2007283529A AU2007283529A1 (en) 2006-08-01 2007-07-27 Eucalyptus extract, method of preparation and therapeutic uses thereof
JP2009522297A JP2010500974A (ja) 2006-08-01 2007-07-27 新規のユーカリ抽出物、その調製方法およびその治療利用法
BRPI0714863-1A BRPI0714863A2 (pt) 2006-08-01 2007-07-27 extrato de eucalipto, processo de preparo e utilizaÇÕes terapÊuticas do mesmo
MX2009000673A MX2009000673A (es) 2006-08-01 2007-07-27 Nuevo extracto de eucalipto, su procedimiento de preparacion y sus utilizaciones terapeuticas.
US12/309,754 US20090324754A1 (en) 2006-08-01 2007-07-27 Eucalyptus extract, method of preparation and therapeutic uses thereof
CA002659162A CA2659162A1 (fr) 2006-08-01 2007-07-27 Nouvel extrait d'eucalyptus, son procede de preparation et ses utilisations therapeutiques
NZ574429A NZ574429A (en) 2006-08-01 2007-07-27 New eucalyptus extract, method of preparation and therapeutic uses thereof
EP07823364A EP2049133A2 (fr) 2006-08-01 2007-07-27 Nouvel extrait d'eucalyptus, son procede de preparation et ses utilisations therapeutiques
TN2009000018A TN2009000018A1 (fr) 2006-08-01 2009-01-19 Nouvel extrait d'eucalyptus, son procede de preparation et ses utilisations therapeutiques
IL196788A IL196788A0 (en) 2006-08-01 2009-01-29 New eucalyptus extract, method of preparation and therapeutic uses thereof
NO20090951A NO20090951L (no) 2006-08-01 2009-03-02 Nytt eukalyptusekstrakt, fremgangsmate for fremstilling og terapeutiske anvendelser derav

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0607201A FR2904557B1 (fr) 2006-08-01 2006-08-01 Nouvel extrait d'eucalyptus, son procede de preparation et ses utilisations therapeutiques
FR0607201 2006-08-01

Publications (2)

Publication Number Publication Date
WO2008017752A2 WO2008017752A2 (fr) 2008-02-14
WO2008017752A3 true WO2008017752A3 (fr) 2008-04-10

Family

ID=37708427

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2007/001309 WO2008017752A2 (fr) 2006-08-01 2007-07-27 Extrait d ' eucalyptus, son procede de preparation et ses utilisations therapeutiques

Country Status (20)

Country Link
US (1) US20090324754A1 (fr)
EP (1) EP2049133A2 (fr)
JP (1) JP2010500974A (fr)
KR (1) KR20090034401A (fr)
CN (1) CN101511378A (fr)
AR (1) AR062165A1 (fr)
AU (1) AU2007283529A1 (fr)
BR (1) BRPI0714863A2 (fr)
CA (1) CA2659162A1 (fr)
FR (1) FR2904557B1 (fr)
IL (1) IL196788A0 (fr)
MA (1) MA30592B1 (fr)
MX (1) MX2009000673A (fr)
NO (1) NO20090951L (fr)
NZ (1) NZ574429A (fr)
RU (1) RU2445112C2 (fr)
TN (1) TN2009000018A1 (fr)
TW (1) TW200820961A (fr)
UA (1) UA99598C2 (fr)
WO (1) WO2008017752A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2926547B1 (fr) * 2008-01-18 2010-04-23 Pf Medicament 5-°1-(decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1h- cyclopropa°a!naphtalen-4-yl)-3-methylbutyl!-2,4,6-trihydroxy -1,3-benzenedicarboxaldehyde en tant que medicaments.
JP5602346B2 (ja) 2008-06-17 2014-10-08 株式会社ロッテ ユーカリ抽出物の調製方法
GB2465228A (en) * 2008-11-15 2010-05-19 Athena Health Patents Inc Analogues of phloroglucinols from eucalyptus plant varieties and related compounds and their use in treating neurodegenerative disorders
CN102085169B (zh) * 2011-01-30 2012-08-29 广州中涵生物科技有限公司 一种使黑头溶解同步收细毛孔的制剂
PT106278B (pt) * 2012-04-26 2018-01-03 Raiz Inst De Investigação Da Floresta E Papel Método para a obtenção de um extrato rico em ácidos triterpénicos a partir da casca de eucalipto
KR102115037B1 (ko) * 2013-12-04 2020-05-25 코웨이 주식회사 상고머리 야테 추출물을 유효성분으로 함유하는 피부 미백용 화장료 조성물
CN106231923A (zh) * 2013-12-18 2016-12-14 斯拉毕思科股份公司 类囊体降低对可口食物欲望的用途
CN109475586A (zh) 2016-06-29 2019-03-15 康纳塞斯创新公司 脱羧的大麻树脂、其用途和制备其的方法
CN109172554A (zh) * 2018-09-06 2019-01-11 淮安安莱生物科技有限公司 大果桉醛c在制备治疗人肝癌的药物方面的应用
KR102212193B1 (ko) 2019-07-15 2021-02-03 박경호 인동등 및 유칼립투스 추출물을 유효성분으로 포함하는 인지기능장애 예방 또는 치료용 조성물

Citations (5)

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FR2329297A1 (fr) * 1975-10-29 1977-05-27 Rougier Yves Inhalateur buccal
JPH08198765A (ja) * 1995-01-31 1996-08-06 Hayami Kinugawa 鎮痛用医薬組成物
US20030031735A1 (en) * 2000-01-18 2003-02-13 Nagaoka Perfumery Co., Ltd Anti-obestic composition
WO2003053336A2 (fr) * 2001-12-19 2003-07-03 The Quigley Corporation Procedes de traitement de malaises neurovasculaires peripheriques
JP2005272431A (ja) * 2004-03-24 2005-10-06 Yukio Kitagawa アロマセラピー品

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JPH11137232A (ja) * 1997-08-02 1999-05-25 Ever Bright Ind Corp ハーブ製品
JP4809980B2 (ja) * 2000-01-18 2011-11-09 長岡香料株式会社 抗動脈硬化症剤
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FR2329297A1 (fr) * 1975-10-29 1977-05-27 Rougier Yves Inhalateur buccal
JPH08198765A (ja) * 1995-01-31 1996-08-06 Hayami Kinugawa 鎮痛用医薬組成物
US20030031735A1 (en) * 2000-01-18 2003-02-13 Nagaoka Perfumery Co., Ltd Anti-obestic composition
WO2003053336A2 (fr) * 2001-12-19 2003-07-03 The Quigley Corporation Procedes de traitement de malaises neurovasculaires peripheriques
JP2005272431A (ja) * 2004-03-24 2005-10-06 Yukio Kitagawa アロマセラピー品

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Also Published As

Publication number Publication date
CN101511378A (zh) 2009-08-19
FR2904557B1 (fr) 2010-04-30
EP2049133A2 (fr) 2009-04-22
FR2904557A1 (fr) 2008-02-08
WO2008017752A2 (fr) 2008-02-14
RU2445112C2 (ru) 2012-03-20
MX2009000673A (es) 2009-02-04
UA99598C2 (ru) 2012-09-10
US20090324754A1 (en) 2009-12-31
AU2007283529A1 (en) 2008-02-14
CA2659162A1 (fr) 2008-02-14
RU2009107166A (ru) 2010-09-10
AR062165A1 (es) 2008-10-22
BRPI0714863A2 (pt) 2013-05-21
TW200820961A (en) 2008-05-16
KR20090034401A (ko) 2009-04-07
TN2009000018A1 (fr) 2010-08-19
NO20090951L (no) 2009-04-24
IL196788A0 (en) 2009-11-18
NZ574429A (en) 2012-01-12
MA30592B1 (fr) 2009-07-01
JP2010500974A (ja) 2010-01-14

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