Classifications

• • C—CHEMISTRY; METALLURGY
  • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
  • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
  • C08F10/00—Homopolymers and copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
• • C—CHEMISTRY; METALLURGY
  • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
  • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
  • C08F110/00—Homopolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
  • C08F110/02—Ethene
• • C—CHEMISTRY; METALLURGY
  • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
  • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
  • C08F110/00—Homopolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
  • C08F110/04—Monomers containing three or four carbon atoms
  • C08F110/06—Propene
• • C—CHEMISTRY; METALLURGY
  • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
  • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
  • C08F210/00—Copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
  • C08F210/02—Ethene
• • C—CHEMISTRY; METALLURGY
  • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
  • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
  • C08F210/00—Copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
  • C08F210/04—Monomers containing three or four carbon atoms
  • C08F210/06—Propene

Definitions

• This invention is directed to group (IV) and group (X) metal complexes with beta- ketoiminato ligands and to the use of these complexes as catalysts for polymerization of ethylene, C 3 -Cio-alpha olefins, C4-C 10 cyclic alkenes and for the copolymerization of ethylene and comonomers.
• Group (IV) and group (X) metal complex catalysts with beta-ketoiminato ligands for use for polymerizing ethylene and alpha olefins are known. See Kim, J., et al, Journal of Organometallic Chemistry 620, 1-7 (2001); Li, X.-F., et al, Organometallics 23, 1223-1230 (2004); Zhang, D., et al, Organometallics 23, 3270-3275 (2004).
• M is selected from the group consisting of titanium, zirconium and hafnium;
• X is selected from the group consisting of halogens, Ci-C 20 hydrocarbons, Ci-C 20 alkoxides and Ci-C 20 amides;
• R is selected from the group consisting of hydrogen, Ci-C 2O hydrocarbons, Ci-C 2O fluorocarbons (includes, for example, fluoroalkyls and fluoroaryls including those with both H and F substituents) and C 3 -C 20 heterocycles;
• R 1 is selected from the group consisting Of C 2 -C 20 hydrocarbons bound by a tetrahedral carbon atom, i.e., where carbon alpha to carbonyl carbon, i.e., the carbon bonded to oxygen of ketoimine moiety is a tetrahedral carbon;
• R 2 is selected from the group consisting of hydrogen, Ci-C 20 hydrocarbons, Ci-C 20 fluorocarbons (
• M is selected from the group consisting of nickel and palladium
• L is a neutral two electron donor (i.e., an uncharged group which fulfills the function of filling the coordination valance of M, e.g., an ether, phosphine or nitrile group)
• X, R, R 1 , R 2 and R 3 are defined as above and where two or more of R, R 1 , R 2 and R 3 can be bonded together to form a ring.
• R 1 and R 2 are bonded together thereby forming (arylimino-alkyl)- spiro[4,5]decan-6-one ligand (two for (I) and one for (H)), i.e., to contain spiro[4,5]decane-6- onato moiety.
• the compounds have the structure:
• R and R 3 are defined as above and R and R 3 can be bonded together to form a ring or have the structure:
• R and R 3 are defined as above and R and R 3 can be bonded together to form a ring.
• X is Cl
• R is H or CF 3 and R 3 is phenyl or fluorinated phenyl and even more preferably the compound contains at least one fluorine atom.
• the compounds (I), (II), (III) and (IV) are useful as catalysts for polymerization of ethylene, C 3 -Ci 0 alpha olefins, and C 4 -Ci 0 cyclic alkenes and for copolymerizing ethylene and comonomer selected from the group consisting of C 3 -Ci 0 alpha olefins, styrene, C 3 -Ci 0 dienes, C 3 -Ci 0 alkenyl halides and C 4 -Ci 0 cyclic alkenes.
• ethylene is polymerized in the presence of a catalytically effective amount of activated compound (I), e.g., activated compound (III), to produce polyethylene of M n in the range of 1,000 to 3,000,000 and polydispersities (PDI) in the range of 1 to 3.
• activated compound (I) e.g., activated compound (III)
• PDI polydispersities
• C 3 -Ci O alpha olefin is polymerized in the presence of a catalytically effective amount of activated compound (I), e.g., activated compound (III), to produce poly(C 3 -Ci 0 alpha olefin) Of M n ranging from 1,000 to 3,000,000 and PDI ranging from 1 to 3.
• activated compound (I) e.g., activated compound (III)
• M n ranging from 1,000 to 3,000,000 and PDI ranging from 1 to 3.
• C 4 -Ci 0 cyclic alkene is polymerized in the presence of a catalytically effective amount of activated compound (I), e.g., activated compound (III), to produce PoIy(C 4 -Ci O cyclic alkene) of M n ranging from 1,000 to 3,000,000 and PDI ranging from 1 to 3.
• activated compound (I) e.g., activated compound (III)
• ethylene and comonomer in a mole ratio of ethylene to comonomer ranging from 1 :99 to 99:1 are copolymerized in the presence of a catalytically effective amount of activated compound (I), e.g., activated compound (III), to produce copolymer of ethylene and said comonomer of M n ranging from 1,000 to 3,000,000.
• activated compound (I) e.g., activated compound (III)
• the polymerizations/copolymerizations are advantageously carried out with the activation being effected by an activating effective amount of methylaluminoxane such that [Al]:[Ti] mole ratio ranges from 100 to 200:1; e.g., 125 to 175: 1.
• the polymerizations/copolymerizations are carried out with the activation being effected by an activating effective amount of methylaluminoxane of compounds of the first embodiment herein such that [Al]: [Zr] mole ratio ranges from 100 to 200: 1; e.g., 150: 1.
• the polymerization/copolymerization are advantageously carried out with the activation being effected by an activating effective amount of methylaluminoxane such that [Al]: [Hf] mole ratio ranges from 100 to 200:1; e.g., 150:1.
• the said polymerizations/copolymerizations can also be carried out in the presence of an activating effective amount of trialkylaluminum/fluorinated borate salts, such as i- Bu 3 Al/Ph 3 C + B(C 6 F 5 ) 4 ⁇ such that [Al]: [B]: [M] mole ratio ranges from 10 to 100:2: 1; e.g., 40:2:1.
• the molecular weights and polydispersities (PDI) are determined by high temperature gel-permeation chromatography using monodisperse polyethylene standards.
• R is H
• the spiroketone (VI) is first formylated using ethyl formate to generate aldehyde which is coupled with R 3 NH 2 under neat conditions in the presence of p-toluenesulfonic acid and phosphorus pentoxide to generate ligand whereupon deprotonation followed by reaction with MX 4 as described above gives compound (III).
• (V) is deprotonated in solvent, e.g., at -78°C with one equivalent of butyllithium followed by reaction with one equivalent trans- [(L) 2 NiX(Cl)].
• the amount of compound (I) or compound (II) per mole of monomer ranges, for example, from 1 to IxIO "6 mmol per mole; i.e., this amount can provide catalytically effective amount.
• the methylaluminoxane mentioned above is an activator for compounds (I)/(III).
• methylaluminoxane reaction with a metal alkyl such as AlR 3 or ZnR 2 followed by reaction with (Ph 3 C) (BAr 4 ), (PhNMe 2 H) (BAr 4 ), Ar 3 B or Ar 3 Al, e.g., trialkylaluminum/fluorinated borate salts, e.g., z-Bu 3 Al/Ph 3 C + B(C 6 F 5 ) 4 ⁇
• Activators for compounds (II)/(IV) are Lewis acids such as (l,5-cyclooctadiene)Ni, Ar 3 B or Ar 3 Al.
• activator means any compound that reacts with (I) or (II) to generate an active catalytic species in situ and the term “activated” means that (I) or (II) has been reacted with activator to convert M of (I) or (II) to cationic form and/or to cause rearrangement of (I) or (II) to a more active or selective form.
• Amounts are given above exemplary for methylaluminoxane activating effective amount.
• Reaction times typically range from 5 minutes to 1 hour.
• Reaction temperatures can range, e.g., from 0 to 5O 0 C.
• a suitable solvent for the catalyst for the polymerizations/copolymerizations is toluene.
• Ti complex Ia The Ti complex Ia was synthesized following the procedure similar to that reported in literature to make phenoxyimine Ti complex with minor modifications.
• ligand 7-(2,2,2-trifluoro-l-phenylimino-ethyl)-spiro[4,5]decan- 6-one (1.29 g, 3.98 mmol) in 20 mL of diethyl ether (Et 2 O) at -78 0 C was added H-BuLi (1.6 M in hexanes, 2.48 niL, 3.98 mmol) dropwise using a gas tight syringe.
• This solution was allowed to slowly return to room temperature and stirred for an additional half hour.
• Ti complex Ib The Ti complex Ib was synthesized following the procedure to make Ia. Thus, ligand 7-[l-(2,6-difluoro-phenylimino)-2,2,2-trifluoro-ethyl]-spiro[4,5]decan-6- one (0.57 g, 1.59 mmol) was reacted with «-BuLi (1.6 M in hexanes, 0.99 mL, 1.59 mmol) and then TiCl 4 (1.0 M in toluene, 0.8 mL, 0.8 mmol) to give a deep red powder that was crystallized from a mixture of toluene/pentane to give the desired complex as a deep red crystalline solid (0.15g, 23%).
• «-BuLi 1.6 M in hexanes, 0.99 mL, 1.59 mmol
• TiCl 4 1.0 M in toluene, 0.8 mL, 0.8 mmol
• Ti complex Ic The Ti complex Ic was synthesized following the procedure to make Ia. Thus, ligand 7-phenyliminomethyl-spiro[4,5]decan ⁇ 6-one (1.24 g, 4.86 mmol) was reacted with «-BuLi (1.6 M in hexanes, 3.03 mL, 4.86 mmol) and then TiCl 4 (1.0 M in toluene, 2.43 mL, 2.43 mmol) to give a deep read powder (81 mg, 6%).
• «-BuLi 1.6 M in hexanes, 3.03 mL, 4.86 mmol
• TiCl 4 1.0 M in toluene, 2.43 mL, 2.43 mmol
• Ti complex Id The Ti complex Id was synthesized following the procedure to make Ia. Thus, ligand 7-[(2,6-difluoro-phenylimino)-methyl-spiro[4,5]decan-6-one (1.03 g, 3.54 mmol) was reacted with «-BuLi (1.6 M in hexanes, 2.21 mL, 3.54 mmol) and then TiCl 4 (1.0 M in toluene, 1.77 mL, 1.77 mmol) gave a deep red powder that was crystallized from toluene to give the desired complex as a deep red crystalline solid (0.83g, 67%).
• «-BuLi 1.6 M in hexanes, 2.21 mL, 3.54 mmol
• TiCl 4 1.0 M in toluene, 1.77 mL, 1.77 mmol
• Ti complex Ie The Ti complex Ie was synthesized following the procedure to make Ia. Thus, ligand 7-[(3,5-difluoro-phenylimino)-methyl]-spiro[4.5]decan-6-one (0.68 g, 2.33 mmol) was reacted with «-BuLi (1.6 M in hexanes, 1.46 mL, 2.33 mmol) and then TiCl 4 (1.0 M in toluene, 1.17 mL, 1.17 mmol) to give a deep red powder that was crystallized from toluene to give the desired complex as a deep red crystalline solid (0.088 g, 11%).
• «-BuLi 1.6 M in hexanes, 1.46 mL, 2.33 mmol
• TiCl 4 1.0 M in toluene, 1.17 mL, 1.17 mmol
• Ti complex If was synthesized following the procedure to make Ia.
• ligand 7-[(pentafluorophenylimino)-methyl]-spiro[4,5]decan-6-one (1.08 g, 3.13 mmol) was reacted with «-BuLi (1.6 M in hexanes, 1.96 mL, 3.13 mmol) and then TiCl 4 (1.0 M in toluene, 1.57 mL, 1.57 mmol) to give a deep red powder that was crystallized from toluene to give the desired complex as a deep red crystalline solid (0.80 g, 63%).
• Compound Ig is synthesized as follows: The ligand 7-(2,2,2-trifluoro-l-phenylimino- ethyl)-spiro[4.5]decane-6-one is synthesized as described in Example I. A solution of the ligand in toluene is added to a solution of tetrakis(dimethylamino) zirconium in toluene solvent at room temperature, leading to an immediate color change from light yellow to orange, and then dark red. The resulting solution is stirred overnight to afford after solvent removal the complex L 2 Zr(NMe 2 ) 2 . Then the complex L 2 Zr(NMe 2 ) 2 is dissolved in methylene chloride, and an excess (ca. 10 equivalent) of chlorotrimethylsilane is added. After stirring overnight at 22°C, the solvent is removed under vacuum. The dark red residue is triturated with pentane to afford a yellow solid.
• Compound Ih is synthesized as follows: The ligand 7-(2,2,2-trifluoro-l- phenylimino-ethyl)-spiro[4,5]decane-6-one is synthesized as described in Example I. A solution of the ligand in toluene is added to a solution of tetrakis(dimethylamino) hafnium in toluene solvent at room temperature, leading to an immediate color change. The resulting solution is stirred overnight to afford after solvent removal the complex L 2 Hf(NMe 2 ) 2 . Then the complex L 2 Hf(NMe 2 ) 2 is dissolved in methylene chloride, and an excess (ca. 10 equivalent) of chlorotrimethylsilane is added. After stirring overnight at 22 0 C, the solvent is removed under vacuum. The residue is triturated with pentane to afford compound Ih as a solid.
• Compound Ii is synthesized as follows: The ligand 7-(2,2,2-trifiuoro-l-phenylimino- ethyl)-spiro[4,5]decane-6-one is synthesized as set forth in Example I. The ligand is deprotonated in toluene solvent with one equivalent n-butyllithium at -78 0 C. Then one equivalent of /ra «s-[(Ph 3 P)2NiPh(Cl)] in toluene is added. After stirring overnight at 22 0 C, the suspension is filtered to remove LiCl. Upon concentration of the toluene, crystals of Compound Ii are grown and isolated after decanting the mother liquor.
• the 13 C I N NMMRR a annaallyyssiis indicates that these PE samples have linear structures with non- detectable branching.
• Polymerization is conducted m a 3-ounce Lab-CrestTM pressure reaction vessel equipped with a magnetic stir bar
• the reactor is first conditioned under dynamic vacuum and high temperature and then charged with a 3 mmol of PMAO in toluene and 5 mL of cyclopentene under nitrogen.
• 20 mmol of CAT is dissolved in toluene (3 mL) at room temperature under nitrogen
• the solution is then added to the reactor using a syringe.
• the reactor is adjusted at 70 0 C After 16 h, the reactor contents are poured into methanol/HCl and polymer is isolated by filtration.
• Polymerization is conducted in a 3-ounce Lab-CrestTM pressure reaction vessel equipped with a magnetic stir bar.
• the reactor is under dynamic vacuum and high temperature and then charged with a 3 mmol of PMAO in toluene and 5 mL of norbornene under nitrogen Then 20 mmol of CAT is dissolved in toluene (3 mL) at room temperature under nitrogen The solution is then added to the reactor using a syringe. Finally, the reactor is adjusted at 70 0 C. After 16 h, the reactor contents are poured into methanol/HCl and polymer is isolated by filtration.
• Polymerization is conducted in a 3-ounce Lab-CrestTM pressure reaction vessel equipped with a magnetic stir bar.
• the reactor is charged with 6 mmol of PMAO in toluene under nitrogen.
• 13.2 mL of cyclopentene is introduced.
• CAT is dissolved in toluene (5 mL) at room temperature under nitrogen.
• the solution is then added to the reactor via syringe, such that the fixed [A1]/[M] ratio is 150.
• the reactor is pressurized with ethylene gas and adjusted to the desired pressure and temperature. After the desired period of time, the reactor is vented.
• the polymer is precipitated from methanol/HCl, filtered, and then dried in vacuo to constant weight.

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• 2005
  • 2005-08-08 JP JP2007527858A patent/JP2008510001A/ja active Pending
  • 2005-08-08 US US11/629,985 patent/US20090192278A1/en not_active Abandoned
  • 2005-08-08 WO PCT/US2005/027927 patent/WO2006023296A2/en not_active Ceased

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