WO2004028441A3 - Compose heterocyclique pour stimuler ou induire la pousse des cheveux ou des cils et/ou freiner leur chute, composition le contenant, ses utilisations - Google Patents

Compose heterocyclique pour stimuler ou induire la pousse des cheveux ou des cils et/ou freiner leur chute, composition le contenant, ses utilisations Download PDF

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Publication number
WO2004028441A3
WO2004028441A3 PCT/FR2003/002823 FR0302823W WO2004028441A3 WO 2004028441 A3 WO2004028441 A3 WO 2004028441A3 FR 0302823 W FR0302823 W FR 0302823W WO 2004028441 A3 WO2004028441 A3 WO 2004028441A3
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WO
WIPO (PCT)
Prior art keywords
cycles
saturated
unsaturated
optionally
alkyl
Prior art date
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PCT/FR2003/002823
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English (en)
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WO2004028441A2 (fr
WO2004028441A8 (fr
Inventor
Christophe Boulle
Roger Rozot
Maria Dalko
Original Assignee
Oreal
Christophe Boulle
Roger Rozot
Maria Dalko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oreal, Christophe Boulle, Roger Rozot, Maria Dalko filed Critical Oreal
Priority to CA002499689A priority Critical patent/CA2499689A1/fr
Priority to AU2003299068A priority patent/AU2003299068B2/en
Priority to JP2005501926A priority patent/JP2006518338A/ja
Priority to EP03798227A priority patent/EP1545708A2/fr
Priority to BR0314490-9A priority patent/BR0314490A/pt
Priority to MXPA05003126A priority patent/MXPA05003126A/es
Publication of WO2004028441A2 publication Critical patent/WO2004028441A2/fr
Publication of WO2004028441A3 publication Critical patent/WO2004028441A3/fr
Publication of WO2004028441A8 publication Critical patent/WO2004028441A8/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

L'invention se rapporte à une composition de soin ou de maquillage des cheveux ou des cils, contenant un composé hétérocyclique de formule (I) ou l'un de ses sels dans laquelle : Hy est un hétérocycle de 4 à 7 atomes comportant éventuellement une fonction carbonyle et/ou une fonction thiocarbonyle, et étant éventuellement substitué par au moins un substituant choisi parmi un halogène, OR, SR, NRR', COR, CSR, NRCONR'R', C(=NR)R', C(=NR)NR'R', NRC(=NR')NR'R'', OCOR, COSR, SCOR, CSNRR', NRCSR', NRCSNR'R', COOR, CONRR', CF3, CN, NRCOR', SO2R', SO2NRR', NRSO2R', les radicaux alkyle, saturés ou insaturés, en C1-C20, les cycles saturés ou insaturés, contenant éventuellement un hétéroatome, ces cycles pouvant être séparés ou accolés, les radicaux alkyle et les cycles pouvant, en outre, être substitués, où R, R', R' et R'', désignent un hydrogène, un radical alkyle en C1-C20 ou un radical aryle, éventuellement substitué ;G représente O, S, NH ; R1, R2 et R3 représentent un hydrogène, un halogène, OR0, SR0, NR0R0', COR0, CSR0, NR0CONR0'R0', C(=NR0)R0', C(=NR0)NR0'R0', NR0C(=NR0')NR0R0' OCOR0, COSR0, SCOR0, CSNR0R0', NR0CSR0', NR0CSNR0'R0', COOR0, CONR0R0', CF3, NO2, CN, NR0COR'0, SO2R'0, SO2NR0R'0, NR0SO2R'0, un radical alkyle, saturé ou insaturé, en C1-C20, au moins un cycle saturé ou insaturé, contenant éventuellement un hétéroatome, les cycles pouvant être séparés ou accolés, les radicaux alkyle et les cycles pouvant, en outre, être substitués, où R0, R0', R0' et R0'', désignent un hydrogène, un radical alkyle en C1-C20 ou un radical aryle, éventuellement substitué.
PCT/FR2003/002823 2002-09-27 2003-09-25 Compose heterocyclique pour stimuler ou induire la pousse des cheveux ou des cils et/ou freiner leur chute, composition le contenant, ses utilisations WO2004028441A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA002499689A CA2499689A1 (fr) 2002-09-27 2003-09-25 Compose heterocyclique pour stimuler ou induire la pousse des cheveux ou des cils et/ou freiner leur chute, composition le contenant, ses utilisations
AU2003299068A AU2003299068B2 (en) 2002-09-27 2003-09-25 Heterocyclic compound for stimulating or inducing hair or eyelash growth and/or for slowing down hair loss, composition containing same, and uses thereof
JP2005501926A JP2006518338A (ja) 2002-09-27 2003-09-25 毛髪又は睫毛の成長を刺激又は誘発させ、及び／又は抜毛を遅延化するための複素環化合物、及びそれを含有する組成物、及びその用途
EP03798227A EP1545708A2 (fr) 2002-09-27 2003-09-25 Compose heterocyclique pour stimuler ou induire la pousse des cheveux ou des cils et/ou freiner leur chute, composition le contenant, ses utilisations
BR0314490-9A BR0314490A (pt) 2002-09-27 2003-09-25 Usos de pelo menos um composto heterocìclico, composições de cuidado ou de maquilagem das fibras queratìnicas, processo de tratamento cosmético das fibras queratìnicas, processo de cuidado cosmético e/ou de maquilagem dos cìlios humanos, processo de cuidado cosmético dos cabelos e/ou do couro cabeludo humanos e compostos heterocìclicos
MXPA05003126A MXPA05003126A (es) 2002-09-27 2003-09-25 Compuesto heterociclico para estimular o inducir el crecimiento del cabello o pestanas y/o frenar la perdida de cabello, c0mposicion que contiene el mismo y usos del mismo.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR02/12018 2002-09-27
FR0212018A FR2845000B1 (fr) 2002-09-27 2002-09-27 Utilisation d'un compose heterocyclique ou de l'un de ses sels pour stimuler ou induire la pousse des cheveux et/ou freiner leur chute
US41546202P 2002-10-03 2002-10-03
US60/415,462 2002-10-03

Publications (3)

Publication Number Publication Date
WO2004028441A2 WO2004028441A2 (fr) 2004-04-08
WO2004028441A3 true WO2004028441A3 (fr) 2004-05-06
WO2004028441A8 WO2004028441A8 (fr) 2007-01-18

Family

ID=31985302

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2003/002823 WO2004028441A2 (fr) 2002-09-27 2003-09-25 Compose heterocyclique pour stimuler ou induire la pousse des cheveux ou des cils et/ou freiner leur chute, composition le contenant, ses utilisations

Country Status (12)

Country Link
US (2) US7294641B2 (fr)
EP (1) EP1545708A2 (fr)
JP (1) JP2006518338A (fr)
KR (1) KR20050067397A (fr)
CN (1) CN1703259A (fr)
AU (1) AU2003299068B2 (fr)
BR (1) BR0314490A (fr)
CA (1) CA2499689A1 (fr)
FR (1) FR2845000B1 (fr)
MX (1) MXPA05003126A (fr)
RU (1) RU2316325C2 (fr)
WO (1) WO2004028441A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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WO2004073594A2 (fr) * 2003-02-12 2004-09-02 L'oreal Utilisation d’un inhibiteur de 15-hydroxy prostaglandine deshydrogenase pour favoriser la pigmentation de la peau ou des phaneres
FR2887444A1 (fr) * 2005-06-28 2006-12-29 Oreal Composes benzylidene-1,3-thiazolidine-2,4-diones, leurs utilisations et compositions pour stimuler ou induire la pousse des fibres keratiniques et/ou freiner leur chute et/ou augmenter leur densite.
US20070078175A1 (en) * 2005-10-05 2007-04-05 L'oreal Administration of novel phenylfurylmethylthiazolidine-2,4-dione and phenylthienylmethylthiazolidine-2,4-dione compounds for stimulating or inducing the growth of keratinous fibers and/or slowing loss thereof
FR2891543A1 (fr) * 2005-10-05 2007-04-06 Oreal Composes phenyl-furyl-methyl-thiazolidine-2,4-diones ou phenyl-thienyl-methyl-thiazolidine-2,4-diones ; utilisations pour stimuler ou induire la pousse des fibres keratiniques et/ou freiner leur chute ; compositions le contenant
US20080059313A1 (en) * 2006-08-30 2008-03-06 Oblong John E Hair care compositions, methods, and articles of commerce that can increase the appearance of thicker and fuller hair
WO2009107072A1 (fr) * 2008-02-29 2009-09-03 The Procter & Gamble Company Compositions de traitement capillaire et procédés d'augmentation du diamètre des cheveux
US20080275118A1 (en) * 2008-06-12 2008-11-06 Shaw Mari M Health and cosmetic composition and regime for stimulating hair growth and thickening on the head, including the scalp, eyelashes, and eyebrows, and which discourages hair loss
DE102009044974A1 (de) * 2009-07-23 2011-01-27 Henkel Ag & Co. Kgaa Verwendung von Dihydroquercetin und mindestens einer Aminosäure zur positiven Beeinflussung des natürlichen Pigmentierungsprozesses
EP2515903A4 (fr) * 2009-12-23 2013-07-10 Peter Maccallum Cancer Inst Composés, leurs préparations et leurs utilisations
WO2011082382A2 (fr) * 2009-12-31 2011-07-07 The Trustees Of Columbia University In The City Of New York Procédés pour la détection et la régulation de l'alopécie en aires, et de cohortes de gènes de celle-ci
WO2011130419A2 (fr) 2010-04-13 2011-10-20 The Regents Of The University Of California Agents antiviraux et antiparasitaires à large spectre
US10123966B2 (en) 2013-05-16 2018-11-13 The Procter And Gamble Company Hair thickening compositions and methods of use
EP3057973B1 (fr) 2013-10-15 2019-09-04 Case Western Reserve University Compositions comportant un inhibiteur de 15-pdgh pour la cicatrisation de plaies
CN104306168B (zh) * 2014-10-15 2017-05-24 华东师范大学 氮‑(4‑氯‑2,5‑二甲氧基苯基)‑5‑异丙基‑2‑甲氧基苯磺酰胺在促进毛发生长的应用
JP2018511581A (ja) 2015-03-08 2018-04-26 ケース ウエスタン リザーブ ユニバーシティ 線維症を処置するための短鎖デヒドロゲナーゼ活性阻害剤
WO2018102552A1 (fr) 2016-11-30 2018-06-07 Case Western Reserve University Combinaisons d'inhibiteurs de 15-pgdh avec des corcostéroïdes et/ou des inhibiteurs du tnf et leurs utilisations
CN110573154A (zh) 2017-02-06 2019-12-13 卡斯西部储备大学 调节短链脱氢酶活性的组合物和方法
CR20210328A (es) 2018-11-21 2021-12-02 Univ Case Western Reserve Composiciones y métodos para modular la actividad de deshidrogenasas de cadena corta

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WO1998053790A2 (fr) * 1997-05-30 1998-12-03 Texas Biotechnology Corporation Composes pouvant inhiber le facteur de croissance de l'endothelium vasculaire pour l'empecher de se fixer a ses recepteurs
JPH11302280A (ja) * 1998-04-17 1999-11-02 Ono Pharmaceut Co Ltd チアゾリジン誘導体、およびその誘導体を有効成分とする医薬
WO2000010573A1 (fr) * 1998-08-21 2000-03-02 Viropharma Incorporated Composes, compositions et procedes pour traiter des infections virales et les maladies qui y sont liees
WO2000032598A1 (fr) * 1998-12-04 2000-06-08 Structural Bioinformatics Inc. Methodes et compositions destines au traitement de maladiesnflammatoires a base d'inhibiteurs de l'activite du facteur de necrose tumorale
WO2001062237A2 (fr) * 2000-02-23 2001-08-30 Orentreich Foundation For The Advancement Of Science, Inc. Methodes et compositions de traitement de l'alopecie et d'autres troubles de l'appareil pilosebace
WO2002026706A2 (fr) * 2000-09-29 2002-04-04 Bayer Pharmaceuticals Corporation Inhibiteurs de 17-beta-hydroxysteroide deshydrogenase ii
WO2002074752A1 (fr) * 2001-03-15 2002-09-26 Astrazeneca Ab Inhibiteurs de metalloproteinases
WO2003072033A2 (fr) * 2002-02-21 2003-09-04 Triad Therapeutics, Inc. Mimetiques de ligands communs: thiazolidinediones et rhodanines

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WO2004073594A2 (fr) * 2003-02-12 2004-09-02 L'oreal Utilisation d’un inhibiteur de 15-hydroxy prostaglandine deshydrogenase pour favoriser la pigmentation de la peau ou des phaneres

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US4241073A (en) * 1978-05-23 1980-12-23 Lilly Industries Limited Treatment of immediate hypersensitivity diseases with aryl hydantoins
DE4027038A1 (de) * 1990-08-27 1992-03-05 Wella Ag 3-amino-5-benzyliden-2-thioxo-thiazolidin-4- one, verfahren zu deren herstellung und diese enthaltendes kosmetisches mittel
WO1998053790A2 (fr) * 1997-05-30 1998-12-03 Texas Biotechnology Corporation Composes pouvant inhiber le facteur de croissance de l'endothelium vasculaire pour l'empecher de se fixer a ses recepteurs
JPH11302280A (ja) * 1998-04-17 1999-11-02 Ono Pharmaceut Co Ltd チアゾリジン誘導体、およびその誘導体を有効成分とする医薬
WO2000010573A1 (fr) * 1998-08-21 2000-03-02 Viropharma Incorporated Composes, compositions et procedes pour traiter des infections virales et les maladies qui y sont liees
WO2000032598A1 (fr) * 1998-12-04 2000-06-08 Structural Bioinformatics Inc. Methodes et compositions destines au traitement de maladiesnflammatoires a base d'inhibiteurs de l'activite du facteur de necrose tumorale
WO2001062237A2 (fr) * 2000-02-23 2001-08-30 Orentreich Foundation For The Advancement Of Science, Inc. Methodes et compositions de traitement de l'alopecie et d'autres troubles de l'appareil pilosebace
WO2002026706A2 (fr) * 2000-09-29 2002-04-04 Bayer Pharmaceuticals Corporation Inhibiteurs de 17-beta-hydroxysteroide deshydrogenase ii
WO2002074752A1 (fr) * 2001-03-15 2002-09-26 Astrazeneca Ab Inhibiteurs de metalloproteinases
WO2003072033A2 (fr) * 2002-02-21 2003-09-04 Triad Therapeutics, Inc. Mimetiques de ligands communs: thiazolidinediones et rhodanines

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Also Published As

Publication number Publication date
AU2003299068A1 (en) 2004-04-19
MXPA05003126A (es) 2006-03-09
RU2005112734A (ru) 2006-02-27
KR20050067397A (ko) 2005-07-01
WO2004028441A2 (fr) 2004-04-08
EP1545708A2 (fr) 2005-06-29
FR2845000B1 (fr) 2005-05-27
RU2316325C2 (ru) 2008-02-10
WO2004028441A8 (fr) 2007-01-18
CA2499689A1 (fr) 2004-04-08
US20060008436A1 (en) 2006-01-12
FR2845000A1 (fr) 2004-04-02
US20080076809A1 (en) 2008-03-27
JP2006518338A (ja) 2006-08-10
CN1703259A (zh) 2005-11-30
BR0314490A (pt) 2005-08-02
AU2003299068B2 (en) 2008-06-05
US7294641B2 (en) 2007-11-13

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