ATE285410T1 - Naphthyridinderivate oder salze davon - Google Patents
Naphthyridinderivate oder salze davonInfo
- Publication number
- ATE285410T1 ATE285410T1 AT98929751T AT98929751T ATE285410T1 AT E285410 T1 ATE285410 T1 AT E285410T1 AT 98929751 T AT98929751 T AT 98929751T AT 98929751 T AT98929751 T AT 98929751T AT E285410 T1 ATE285410 T1 AT E285410T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- lower alkyl
- salts
- tachykinin receptors
- Prior art date
Links
- 150000005054 naphthyridines Chemical class 0.000 title 1
- 102000007124 Tachykinin Receptors Human genes 0.000 abstract 2
- 108010072901 Tachykinin Receptors Proteins 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000008485 antagonism Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- -1 naphthyridine compound Chemical class 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18727497 | 1997-06-30 | ||
| JP13622598 | 1998-05-19 | ||
| PCT/JP1998/002921 WO1999000388A1 (en) | 1997-06-30 | 1998-06-30 | Novel naphthyridine derivatives or salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285410T1 true ATE285410T1 (de) | 2005-01-15 |
Family
ID=26469856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98929751T ATE285410T1 (de) | 1997-06-30 | 1998-06-30 | Naphthyridinderivate oder salze davon |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6294547B1 (de) |
| EP (1) | EP0997462B1 (de) |
| KR (1) | KR20010014262A (de) |
| AT (1) | ATE285410T1 (de) |
| AU (1) | AU729995B2 (de) |
| CA (1) | CA2295309A1 (de) |
| DE (1) | DE69828284T2 (de) |
| PL (1) | PL337672A1 (de) |
| WO (1) | WO1999000388A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6433174B1 (en) | 1998-12-16 | 2002-08-13 | Nippon Kayaku Kabushiki Kaisha | Process for producing novel naphthyridine derivatives |
| ES2287170T3 (es) * | 2000-10-12 | 2007-12-16 | MERCK & CO., INC. | Aza- y poliaza-naftalenil-carboxamidas utilies como inhibidores de la vih integrasa. |
| AU1152702A (en) | 2000-10-12 | 2002-04-22 | Merck & Co Inc | Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors |
| ATE345129T1 (de) * | 2000-10-12 | 2006-12-15 | Merck & Co Inc | Aza- und polyaza-naphthalenylcarbonsäureamide als hiv-integrase-hemmer |
| CA2432543A1 (en) * | 2000-12-22 | 2002-07-04 | Takeda Chemical Industries, Ltd. | Combination drugs |
| AR036256A1 (es) * | 2001-08-17 | 2004-08-25 | Merck & Co Inc | Sal sodica de un inhibidor de integrasa del vih, procesos para su preparacion, composiciones farmaceuticas que lo contienen y su uso para la manufactura de un medicamento |
| MY130373A (en) * | 2001-10-29 | 2007-06-29 | Malesci Sas | Linear basic compounds having nk-2 antagonist activity and formulations thereof |
| DE60323743D1 (en) * | 2002-03-15 | 2008-11-06 | Merck & Co Inc | N-(substituierte benzyl)-8-hydroxy-1,6-naphthyridin-7- carbonsäureamide als hiv-integrase-hemmer |
| EP2117538A1 (de) | 2007-01-24 | 2009-11-18 | Glaxo Group Limited | Pharmazeutische zusammensetzungen mit 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
| RU2462513C2 (ru) | 2007-05-15 | 2012-09-27 | Трансген С.А. | Векторы для множественной генной экспрессии |
| DE102008059578A1 (de) * | 2008-11-28 | 2010-06-10 | Merck Patent Gmbh | Benzo-Naphtyridin Verbindungen |
| AU2011232058B2 (en) * | 2010-03-26 | 2016-09-08 | Merck Patent Gmbh | Benzonaphthyridinamines as autotaxin inhibitors |
| WO2013109738A1 (en) | 2012-01-17 | 2013-07-25 | The Trustees Of Columbia University In The City Of New York | Novel phosphodiesterase inhibitors and uses thereof |
| ES2776353T3 (es) | 2013-07-17 | 2020-07-30 | Univ Columbia | Inhibidores de la fosfodiesterasa novedosos y usos de los mismos |
| EP3375784A1 (de) * | 2017-03-14 | 2018-09-19 | Artax Biopharma Inc. | Aza-dihydro-acridonderivate |
| EP4534083A4 (de) * | 2022-05-30 | 2025-11-19 | Scinnohub Pharmaceutical Co Ltd | Verwendung von tetrahydronaphthyridinderivaten zur herstellung eines arzneimittels zur vorbeugung und behandlung von adhäsionsbedingten erkrankungen |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3555034A (en) * | 1968-06-18 | 1971-01-12 | American Home Prod | Certain 5,6,7,8-tetrahydro-1,6-naphthyridin-2-ol esters |
| JPS5857379A (ja) * | 1981-10-01 | 1983-04-05 | Nippon Kayaku Co Ltd | ５，６，７，８−テトラヒドロ−１，６−ナフチリジン誘導体およびその製造法 |
| JPS5775983A (en) * | 1980-10-29 | 1982-05-12 | Nippon Kayaku Co Ltd | Novel derivative of 5,6,7,-tetrahydro-2,6-naphthyridine and its preparation |
| IT8124760A0 (it) * | 1980-10-29 | 1981-10-29 | Nippon Kayaku Kk | Derivati di 5,6,7,8-tetraidro-1,6-naftiridina e procedimento per la loro preparazione. |
| US4647566A (en) * | 1984-07-09 | 1987-03-03 | Ciba-Geigy Corporation | Certain ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives in treating anxiety |
| MY105344A (en) | 1990-05-16 | 1994-09-30 | Byk Gulden Lomberg Chemische Fabrik | New sulphonyl compounds |
-
1998
- 1998-06-30 US US09/446,452 patent/US6294547B1/en not_active Expired - Fee Related
- 1998-06-30 PL PL98337672A patent/PL337672A1/xx unknown
- 1998-06-30 DE DE69828284T patent/DE69828284T2/de not_active Expired - Fee Related
- 1998-06-30 AU AU79352/98A patent/AU729995B2/en not_active Ceased
- 1998-06-30 KR KR1019997012374A patent/KR20010014262A/ko not_active Withdrawn
- 1998-06-30 CA CA002295309A patent/CA2295309A1/en not_active Abandoned
- 1998-06-30 EP EP98929751A patent/EP0997462B1/de not_active Expired - Lifetime
- 1998-06-30 AT AT98929751T patent/ATE285410T1/de not_active IP Right Cessation
- 1998-06-30 WO PCT/JP1998/002921 patent/WO1999000388A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0997462B1 (de) | 2004-12-22 |
| AU7935298A (en) | 1999-01-19 |
| DE69828284D1 (de) | 2005-01-27 |
| PL337672A1 (en) | 2000-08-28 |
| EP0997462A4 (de) | 2001-07-04 |
| EP0997462A1 (de) | 2000-05-03 |
| AU729995B2 (en) | 2001-02-22 |
| WO1999000388A1 (en) | 1999-01-07 |
| CA2295309A1 (en) | 1999-01-07 |
| US6294547B1 (en) | 2001-09-25 |
| DE69828284T2 (de) | 2005-12-08 |
| KR20010014262A (ko) | 2001-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |