ATE285410T1 - Naphthyridinderivate oder salze davon - Google Patents
Naphthyridinderivate oder salze davonInfo
- Publication number
- ATE285410T1 ATE285410T1 AT98929751T AT98929751T ATE285410T1 AT E285410 T1 ATE285410 T1 AT E285410T1 AT 98929751 T AT98929751 T AT 98929751T AT 98929751 T AT98929751 T AT 98929751T AT E285410 T1 ATE285410 T1 AT E285410T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- lower alkyl
- salts
- tachykinin receptors
- Prior art date
Links
- 150000005054 naphthyridines Chemical class 0.000 title 1
- 102000007124 Tachykinin Receptors Human genes 0.000 abstract 2
- 108010072901 Tachykinin Receptors Proteins 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000008485 antagonism Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- -1 naphthyridine compound Chemical class 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18727497 | 1997-06-30 | ||
| JP13622598 | 1998-05-19 | ||
| PCT/JP1998/002921 WO1999000388A1 (en) | 1997-06-30 | 1998-06-30 | Novel naphthyridine derivatives or salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285410T1 true ATE285410T1 (de) | 2005-01-15 |
Family
ID=26469856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98929751T ATE285410T1 (de) | 1997-06-30 | 1998-06-30 | Naphthyridinderivate oder salze davon |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6294547B1 (de) |
| EP (1) | EP0997462B1 (de) |
| KR (1) | KR20010014262A (de) |
| AT (1) | ATE285410T1 (de) |
| AU (1) | AU729995B2 (de) |
| CA (1) | CA2295309A1 (de) |
| DE (1) | DE69828284T2 (de) |
| PL (1) | PL337672A1 (de) |
| WO (1) | WO1999000388A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1142892A4 (de) * | 1998-12-16 | 2003-09-17 | Nippon Kayaku Kk | Verfahren zur herstellung neuartiger naphtyridin-derivate |
| DE60128936T2 (de) * | 2000-10-12 | 2008-04-10 | Merck & Co, Inc. | Aza- und polyaza-naphthalenylcarbonsäureamide als hiv-integrase-hemmer |
| CA2425625A1 (en) * | 2000-10-12 | 2002-07-18 | Merck & Co., Inc. | Aza-and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors |
| WO2002030931A2 (en) | 2000-10-12 | 2002-04-18 | Merck & Co., Inc. | Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors |
| EP1352659A4 (de) * | 2000-12-22 | 2004-06-30 | Takeda Chemical Industries Ltd | Kombinationsarzneistoffe |
| AR036256A1 (es) * | 2001-08-17 | 2004-08-25 | Merck & Co Inc | Sal sodica de un inhibidor de integrasa del vih, procesos para su preparacion, composiciones farmaceuticas que lo contienen y su uso para la manufactura de un medicamento |
| MY130373A (en) * | 2001-10-29 | 2007-06-29 | Malesci Sas | Linear basic compounds having nk-2 antagonist activity and formulations thereof |
| WO2003077857A2 (en) * | 2002-03-15 | 2003-09-25 | Merck & Co., Inc. | N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7- carboxamides useful as hiv integrase inhibitors |
| JP2010516734A (ja) | 2007-01-24 | 2010-05-20 | グラクソ グループ リミテッド | ３，５−ジアミノ−６−（２，３−ジクロロフェニル）−１，２，４−トリアジンまたはｒ（−）−２，４−ジアミノ−５−（２，３−ジクロロフェニル）−６−フルオロメチルピリミジンを含む医薬組成物 |
| JP5474767B2 (ja) * | 2007-05-15 | 2014-04-16 | トランジェーヌ、ソシエテ、アノニム | 多重遺伝子発現のためのベクター |
| DE102008059578A1 (de) | 2008-11-28 | 2010-06-10 | Merck Patent Gmbh | Benzo-Naphtyridin Verbindungen |
| EP2552914B1 (de) * | 2010-03-26 | 2015-11-11 | Merck Patent GmbH | Benzonaphthyridinamine als autotaxin-inhibitoren |
| WO2013109738A1 (en) | 2012-01-17 | 2013-07-25 | The Trustees Of Columbia University In The City Of New York | Novel phosphodiesterase inhibitors and uses thereof |
| WO2015009930A2 (en) | 2013-07-17 | 2015-01-22 | The Trustees Of Columbia University In The City Of New York | Novel phosphodiesterase inhibitors and uses thereof |
| EP3375784A1 (de) * | 2017-03-14 | 2018-09-19 | Artax Biopharma Inc. | Aza-dihydro-acridonderivate |
| JP2025519195A (ja) * | 2022-05-30 | 2025-06-24 | 賽諾哈勃薬業（成都）有限公司 | 癒着関連疾患を予防・治療する薬物の調製におけるテトラヒドロナフチリヂン誘導体の使用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3555034A (en) * | 1968-06-18 | 1971-01-12 | American Home Prod | Certain 5,6,7,8-tetrahydro-1,6-naphthyridin-2-ol esters |
| JPS5775983A (en) | 1980-10-29 | 1982-05-12 | Nippon Kayaku Co Ltd | Novel derivative of 5,6,7,-tetrahydro-2,6-naphthyridine and its preparation |
| JPS5857379A (ja) | 1981-10-01 | 1983-04-05 | Nippon Kayaku Co Ltd | ５，６，７，８−テトラヒドロ−１，６−ナフチリジン誘導体およびその製造法 |
| IT8124760A0 (it) * | 1980-10-29 | 1981-10-29 | Nippon Kayaku Kk | Derivati di 5,6,7,8-tetraidro-1,6-naftiridina e procedimento per la loro preparazione. |
| US4647566A (en) | 1984-07-09 | 1987-03-03 | Ciba-Geigy Corporation | Certain ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives in treating anxiety |
| MY105344A (en) | 1990-05-16 | 1994-09-30 | Byk Gulden Lomberg Chemische Fabrik | New sulphonyl compounds |
-
1998
- 1998-06-30 CA CA002295309A patent/CA2295309A1/en not_active Abandoned
- 1998-06-30 US US09/446,452 patent/US6294547B1/en not_active Expired - Fee Related
- 1998-06-30 PL PL98337672A patent/PL337672A1/xx unknown
- 1998-06-30 WO PCT/JP1998/002921 patent/WO1999000388A1/ja not_active Ceased
- 1998-06-30 KR KR1019997012374A patent/KR20010014262A/ko not_active Withdrawn
- 1998-06-30 EP EP98929751A patent/EP0997462B1/de not_active Expired - Lifetime
- 1998-06-30 DE DE69828284T patent/DE69828284T2/de not_active Expired - Fee Related
- 1998-06-30 AU AU79352/98A patent/AU729995B2/en not_active Ceased
- 1998-06-30 AT AT98929751T patent/ATE285410T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL337672A1 (en) | 2000-08-28 |
| EP0997462A4 (de) | 2001-07-04 |
| EP0997462B1 (de) | 2004-12-22 |
| EP0997462A1 (de) | 2000-05-03 |
| KR20010014262A (ko) | 2001-02-26 |
| WO1999000388A1 (en) | 1999-01-07 |
| DE69828284D1 (de) | 2005-01-27 |
| US6294547B1 (en) | 2001-09-25 |
| AU729995B2 (en) | 2001-02-22 |
| AU7935298A (en) | 1999-01-19 |
| CA2295309A1 (en) | 1999-01-07 |
| DE69828284T2 (de) | 2005-12-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |