WO2002009734A1 - Inhibiteurs d'absorption de sucre et leur procede de production - Google Patents
Inhibiteurs d'absorption de sucre et leur procede de production Download PDFInfo
- Publication number
- WO2002009734A1 WO2002009734A1 PCT/JP2001/006436 JP0106436W WO0209734A1 WO 2002009734 A1 WO2002009734 A1 WO 2002009734A1 JP 0106436 W JP0106436 W JP 0106436W WO 0209734 A1 WO0209734 A1 WO 0209734A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- evening primrose
- absorption inhibitors
- sugar absorption
- primrose seeds
- defatted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
- Fats And Perfumes (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001276682A AU2001276682A1 (en) | 2000-08-01 | 2001-07-26 | Sugar absorption inhibitors and process for producing the same |
JP2002515287A JP4873824B2 (ja) | 2000-08-01 | 2001-07-26 | 糖質吸収阻害剤およびその製造方法 |
EP01954345A EP1312374B1 (en) | 2000-08-01 | 2001-07-26 | Primrose seed extracts as sugar absorption inhibitors and process for producing the same |
US10/343,488 US6932990B2 (en) | 2000-08-01 | 2001-07-26 | Carbohydrate absorption inhibitor and method for manufacturing the same |
DE60135760T DE60135760D1 (de) | 2000-08-01 | 2001-07-26 | Nachtkerzensamenextrakte als inhibitoren der zuckerabsorption und deren herstellungsprozess |
US10/803,873 US20060024396A1 (en) | 2000-08-01 | 2004-03-19 | Method of treating diabetes and obesity using carbohydrate absorption inhibitors |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000-232930 | 2000-08-01 | ||
JP2000232930 | 2000-08-01 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/803,873 Division US20060024396A1 (en) | 2000-08-01 | 2004-03-19 | Method of treating diabetes and obesity using carbohydrate absorption inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002009734A1 true WO2002009734A1 (fr) | 2002-02-07 |
WO2002009734A8 WO2002009734A8 (fr) | 2002-02-28 |
Family
ID=18725531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2001/006436 WO2002009734A1 (fr) | 2000-08-01 | 2001-07-26 | Inhibiteurs d'absorption de sucre et leur procede de production |
Country Status (8)
Country | Link |
---|---|
US (2) | US6932990B2 (ja) |
EP (1) | EP1312374B1 (ja) |
JP (1) | JP4873824B2 (ja) |
CN (1) | CN1268351C (ja) |
AT (1) | ATE407689T1 (ja) |
AU (1) | AU2001276682A1 (ja) |
DE (1) | DE60135760D1 (ja) |
WO (1) | WO2002009734A1 (ja) |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030075947A (ko) * | 2002-03-19 | 2003-09-26 | 제네티카 주식회사 | 신 혈관형성을 억제하는 물질 |
WO2004009094A1 (en) * | 2002-07-24 | 2004-01-29 | Ohio University | Methods and compositions for treating diabetes mellitis |
JP2004352644A (ja) * | 2003-05-29 | 2004-12-16 | Oriza Yuka Kk | 抗ピロリ菌組成物 |
WO2005032570A1 (ja) * | 2003-10-06 | 2005-04-14 | Oryza Oil & Fat Chemical Co., Ltd. | ダイエット用組成物 |
JP2006001872A (ja) * | 2004-06-16 | 2006-01-05 | Kanebo Ltd | α−グルコシダーゼ阻害剤及びそれを用いた食品 |
JP2006056850A (ja) * | 2004-08-23 | 2006-03-02 | Suntory Ltd | リパーゼ阻害剤 |
WO2006030567A1 (en) * | 2004-09-13 | 2006-03-23 | Chuon Co., Ltd. | Carbohydrase inhibitors derived from fagaceous plants and use thereof |
WO2006030929A1 (en) * | 2004-09-13 | 2006-03-23 | Chuon Co., Ltd. | Carbohydrase inhibitors derived from chestnut and use thereof |
JP2006335758A (ja) * | 2003-10-06 | 2006-12-14 | Oriza Yuka Kk | ダイエット用組成物 |
JP2007518420A (ja) * | 2004-01-26 | 2007-07-12 | エヌ.ブイ.・ヌートリシア | アミラーゼによって誘発される澱粉分解を阻害することに基づく、改善された半固体食品及びその製造方法 |
JP2010184909A (ja) * | 2009-02-13 | 2010-08-26 | Rheology Kino Shokuhin Kenkyusho:Kk | 機能性組成物およびこの組成物を含有する医薬又は健康食品 |
US20110021417A1 (en) * | 2003-09-19 | 2011-01-27 | Rhoades Jonathan Robert | Compositions comprising oligosaccharides |
JP2014198684A (ja) * | 2013-03-29 | 2014-10-23 | サンスター株式会社 | 血糖代謝改善剤 |
WO2019131759A1 (ja) * | 2017-12-27 | 2019-07-04 | サントリーホールディングス株式会社 | 腸管バリア機能改善用組成物 |
JP6998108B2 (ja) | 2016-03-07 | 2022-01-18 | 株式会社ダイセル | ウロリチン類を含有するα-グルコシダーゼ活性阻害剤、およびウロリチン類を含有する血糖値上昇抑制剤 |
WO2022085602A1 (ja) * | 2020-10-20 | 2022-04-28 | サントリーホールディングス株式会社 | Tgr5活性化用組成物 |
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---|---|---|---|---|
US20020035071A1 (en) * | 1997-07-08 | 2002-03-21 | Josef Pitha | Mimicking the metabolic effects of caloric restriction by administration of glucose antimetabolites |
US8563522B2 (en) * | 1997-07-08 | 2013-10-22 | The Iams Company | Method of maintaining and/or attenuating a decline in quality of life |
US7713546B1 (en) * | 2001-04-03 | 2010-05-11 | Soft Gel Technologies, Inc. | Corosolic acid formulation and its application for weight-loss management and blood sugar balance |
US7666459B2 (en) * | 2001-09-12 | 2010-02-23 | The Procter & Gamble Company | Pet food compositions |
US20050158294A1 (en) | 2003-12-19 | 2005-07-21 | The Procter & Gamble Company | Canine probiotic Bifidobacteria pseudolongum |
US8877178B2 (en) | 2003-12-19 | 2014-11-04 | The Iams Company | Methods of use of probiotic bifidobacteria for companion animals |
US20050251265A1 (en) * | 2004-05-07 | 2005-11-10 | Calandruccio James H | Trapezium implant for thumb and method |
US20050249837A1 (en) * | 2004-05-10 | 2005-11-10 | The Procter & Gamble Company | Processes for preparing plant matter extracts and pet food compositions |
US20090252834A1 (en) * | 2004-05-10 | 2009-10-08 | Michael Griffin Hayek | Compositions comprising glucose anti-metabolites |
MX292792B (es) | 2004-06-04 | 2011-11-29 | Horizon Science Pty Ltd | Edulcorante natural. |
JP2006016330A (ja) * | 2004-06-30 | 2006-01-19 | Suntory Ltd | 脂肪燃焼促進剤 |
US20060051435A1 (en) * | 2004-08-19 | 2006-03-09 | Udell Ronald G | Nutritional supplement for body fat reduction |
JP4772684B2 (ja) * | 2004-08-30 | 2011-09-14 | 武田薬品工業株式会社 | スクリーニング方法 |
PL1885383T3 (pl) | 2005-05-31 | 2017-06-30 | Iams Europe B.V. | Kocie probiotyczne bifidobakterie |
EP2261323A1 (en) | 2005-05-31 | 2010-12-15 | The Iams Company | Feline probiotic lactobacilli |
CA2608865C (en) * | 2005-06-03 | 2015-08-25 | Horizon Science Pty Ltd | Molasses extract having body mass redistribution properties |
US20070036874A1 (en) * | 2005-08-05 | 2007-02-15 | Litao Zhong | Compositions and methods for controlling glucose and lipid uptake from foods |
KR100829083B1 (ko) | 2006-07-28 | 2008-05-16 | 재단법인 제주하이테크산업진흥원 | 생리활성을 갖는 애기달맞이 추출물 |
US9364016B2 (en) * | 2006-09-19 | 2016-06-14 | The Product Makers (Australia) Pty Ltd | Extracts derived from sugar cane and a process for their manufacture |
WO2008093303A2 (en) * | 2007-02-01 | 2008-08-07 | The Iams Company | Method for decreasing inflammation and stress in a mammal using glucose antimetaboltes, avocado or avocado extracts |
JP2010516805A (ja) * | 2007-02-01 | 2010-05-20 | ザ アイムス カンパニー | 哺乳動物における炎症及び酸化ストレスの低下方法 |
EP2303252A1 (en) | 2008-05-15 | 2011-04-06 | Alois Jungbauer | Compounds for the treatment of metabolic syndrome and insulin resistance |
US9771199B2 (en) | 2008-07-07 | 2017-09-26 | Mars, Incorporated | Probiotic supplement, process for making, and packaging |
KR102300471B1 (ko) * | 2008-08-22 | 2021-09-30 | 비포 파마 테크놀로지 리미티드 | 가교결합된 양이온교환 폴리머, 조성물 및 고칼륨혈증 치료 용도 |
TWI444195B (zh) * | 2008-10-08 | 2014-07-11 | Pokka Corp | Anti-avian influenza virus agents and products containing anti-avian influenza virus agents |
US10104903B2 (en) | 2009-07-31 | 2018-10-23 | Mars, Incorporated | Animal food and its appearance |
CN102018766B (zh) | 2009-09-16 | 2013-03-06 | 博仲盛景医药技术(北京)有限公司 | 一种植物提取物、其提取方法和用途及含有这种提取物的组合物 |
AU2012214104C1 (en) | 2011-02-08 | 2017-08-03 | Poly Gain Pte Ltd | Sugar extracts |
RU2451506C1 (ru) * | 2011-06-02 | 2012-05-27 | Сергей Юрьевич Лешков | Комбинация для лечения сахарного диабета и его осложнений |
MY171216A (en) | 2012-08-28 | 2019-10-02 | The Product Makers Australia Pty Ltd | Extraction method |
CN105722520A (zh) | 2013-08-16 | 2016-06-29 | 产品制造商(澳大利亚)有限公司 | 甘蔗衍生提取物及治疗方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0423419A1 (en) * | 1989-10-19 | 1991-04-24 | Mitsui Norin Co., Ltd. | Inhibitive agent against activity of alpha-amylase |
WO1997023210A1 (fr) * | 1995-12-26 | 1997-07-03 | Suntory Limited | Agent anti-obesite dont le principe actif est la procyanidine |
JPH09176019A (ja) * | 1995-12-26 | 1997-07-08 | Suntory Ltd | 糖質分解消化酵素阻害剤並びにこれを配合した医薬品および飲食品 |
WO2000018416A1 (en) * | 1998-09-30 | 2000-04-06 | Industrial Research Limited | Antioxidant compositions and process for their preparation |
-
2001
- 2001-07-26 DE DE60135760T patent/DE60135760D1/de not_active Expired - Lifetime
- 2001-07-26 AU AU2001276682A patent/AU2001276682A1/en not_active Abandoned
- 2001-07-26 WO PCT/JP2001/006436 patent/WO2002009734A1/ja active IP Right Grant
- 2001-07-26 AT AT01954345T patent/ATE407689T1/de not_active IP Right Cessation
- 2001-07-26 EP EP01954345A patent/EP1312374B1/en not_active Expired - Lifetime
- 2001-07-26 US US10/343,488 patent/US6932990B2/en not_active Expired - Fee Related
- 2001-07-26 JP JP2002515287A patent/JP4873824B2/ja not_active Expired - Lifetime
- 2001-07-26 CN CNB01816661XA patent/CN1268351C/zh not_active Expired - Fee Related
-
2004
- 2004-03-19 US US10/803,873 patent/US20060024396A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0423419A1 (en) * | 1989-10-19 | 1991-04-24 | Mitsui Norin Co., Ltd. | Inhibitive agent against activity of alpha-amylase |
WO1997023210A1 (fr) * | 1995-12-26 | 1997-07-03 | Suntory Limited | Agent anti-obesite dont le principe actif est la procyanidine |
JPH09176019A (ja) * | 1995-12-26 | 1997-07-08 | Suntory Ltd | 糖質分解消化酵素阻害剤並びにこれを配合した医薬品および飲食品 |
WO2000018416A1 (en) * | 1998-09-30 | 2000-04-06 | Industrial Research Limited | Antioxidant compositions and process for their preparation |
Non-Patent Citations (7)
Title |
---|
ARAKI HIROKO ET AL.: "Effects of polyphenols on the activities of salivary and pancreatic alpha-amylases", KIYO-SEITOKU EIYO TANKI DAIGAKU, vol. 25, 1994, pages 15 - 20, XP002948559 * |
CANNEL RICHARD J.P.: "Purification and characterization of pentagalloylglucose, an alpha-glucosidase inhibitor/antibiotic from the freshwater green alga spirogyra varians", BIOCHEM. J., vol. 255, no. 3, pages 937 - 941, XP002948558 * |
CHEMICAL ABSTRACTS, vol. 124, no. 23, 1996, Columbus, Ohio, US; abstract no. 124:312296, LU FEI ET AL.: "Phenolic antioxidant components of evening primrose" page 694; XP002948562 * |
HONDA MIWA ET AL.: "Inhibition of rat small intestinal sucrase and alpha-glucosidase activities by tea polyphenols", BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, vol. 57, no. 1, 1993, pages 123 - 124, XP002948557 * |
QUESADA CRISTINA ET AL.: "Phenolic inhibitors of alpha-amylase ans trypsin enzymes by extracts from pears, lentils and cocoa", J. FOOD PROTECTION, vol. 59, no. 2, 1996, pages 185 - 192, XP002948556 * |
SHAHIDI FEREIDOON ET AL.: "Antioxidant activity of phenolic extracts of evening primrose(oenothera biennis): a preliminary study", J. FOOD LIPIDS, vol. 4, no. 2, 1997, pages 75 - 86, XP002948560 * |
WETTASINGHE MAHINDA ET AL.: "Evening primrose meal: A source of natural antioxidants and scavenger og hydrogen peroxide and oxygen-derived free radicals", J. AGRIC. FOOD CHEM., vol. 47, no. 5, pages 1801 - 1812, XP002948561 * |
Cited By (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030075947A (ko) * | 2002-03-19 | 2003-09-26 | 제네티카 주식회사 | 신 혈관형성을 억제하는 물질 |
WO2004009094A1 (en) * | 2002-07-24 | 2004-01-29 | Ohio University | Methods and compositions for treating diabetes mellitis |
JP4541662B2 (ja) * | 2003-05-29 | 2010-09-08 | オリザ油化株式会社 | 抗ピロリ菌組成物 |
JP2004352644A (ja) * | 2003-05-29 | 2004-12-16 | Oriza Yuka Kk | 抗ピロリ菌組成物 |
US20110021417A1 (en) * | 2003-09-19 | 2011-01-27 | Rhoades Jonathan Robert | Compositions comprising oligosaccharides |
US8802164B2 (en) | 2003-10-06 | 2014-08-12 | Oryza Oil & Fat Chemical Co., Ltd. | Method for promoting carnitine palmitoyltransferase activity using green coffee bean extract |
JP4499665B2 (ja) * | 2003-10-06 | 2010-07-07 | オリザ油化株式会社 | ダイエット用組成物 |
WO2005032570A1 (ja) * | 2003-10-06 | 2005-04-14 | Oryza Oil & Fat Chemical Co., Ltd. | ダイエット用組成物 |
JPWO2005032570A1 (ja) * | 2003-10-06 | 2007-11-15 | オリザ油化株式会社 | ダイエット用組成物 |
JP2006335758A (ja) * | 2003-10-06 | 2006-12-14 | Oriza Yuka Kk | ダイエット用組成物 |
JP2007518420A (ja) * | 2004-01-26 | 2007-07-12 | エヌ.ブイ.・ヌートリシア | アミラーゼによって誘発される澱粉分解を阻害することに基づく、改善された半固体食品及びその製造方法 |
JP2006001872A (ja) * | 2004-06-16 | 2006-01-05 | Kanebo Ltd | α−グルコシダーゼ阻害剤及びそれを用いた食品 |
WO2006022227A1 (ja) * | 2004-08-23 | 2006-03-02 | Suntory Limited | リパーゼ阻害剤 |
JP2006056850A (ja) * | 2004-08-23 | 2006-03-02 | Suntory Ltd | リパーゼ阻害剤 |
JP2008512345A (ja) * | 2004-09-13 | 2008-04-24 | 隆廣 辻田 | 栗由来の糖質分解酵素阻害物質、及びその用途 |
JP2006104181A (ja) * | 2004-09-13 | 2006-04-20 | Takahiro Tsujita | ブナ科植物由来の糖質分解酵素阻害物質、及びその用途 |
WO2006030929A1 (en) * | 2004-09-13 | 2006-03-23 | Chuon Co., Ltd. | Carbohydrase inhibitors derived from chestnut and use thereof |
WO2006030567A1 (en) * | 2004-09-13 | 2006-03-23 | Chuon Co., Ltd. | Carbohydrase inhibitors derived from fagaceous plants and use thereof |
JP2010184909A (ja) * | 2009-02-13 | 2010-08-26 | Rheology Kino Shokuhin Kenkyusho:Kk | 機能性組成物およびこの組成物を含有する医薬又は健康食品 |
JP2014198684A (ja) * | 2013-03-29 | 2014-10-23 | サンスター株式会社 | 血糖代謝改善剤 |
JP6998108B2 (ja) | 2016-03-07 | 2022-01-18 | 株式会社ダイセル | ウロリチン類を含有するα-グルコシダーゼ活性阻害剤、およびウロリチン類を含有する血糖値上昇抑制剤 |
WO2019131759A1 (ja) * | 2017-12-27 | 2019-07-04 | サントリーホールディングス株式会社 | 腸管バリア機能改善用組成物 |
JPWO2019131759A1 (ja) * | 2017-12-27 | 2020-12-24 | サントリーホールディングス株式会社 | 腸管バリア機能改善用組成物 |
JP7252904B2 (ja) | 2017-12-27 | 2023-04-05 | サントリーホールディングス株式会社 | 腸管バリア機能改善用組成物 |
WO2022085602A1 (ja) * | 2020-10-20 | 2022-04-28 | サントリーホールディングス株式会社 | Tgr5活性化用組成物 |
Also Published As
Publication number | Publication date |
---|---|
EP1312374A4 (en) | 2004-04-21 |
CN1268351C (zh) | 2006-08-09 |
DE60135760D1 (de) | 2008-10-23 |
US6932990B2 (en) | 2005-08-23 |
AU2001276682A1 (en) | 2002-02-13 |
US20030161903A1 (en) | 2003-08-28 |
CN1468106A (zh) | 2004-01-14 |
WO2002009734A8 (fr) | 2002-02-28 |
US20060024396A1 (en) | 2006-02-02 |
EP1312374A1 (en) | 2003-05-21 |
ATE407689T1 (de) | 2008-09-15 |
EP1312374B1 (en) | 2008-09-10 |
JP4873824B2 (ja) | 2012-02-08 |
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