WO1984000105A1 - Preparation medicinale ayant un effet antitumoral - Google Patents

Preparation medicinale ayant un effet antitumoral Download PDF

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Publication number
WO1984000105A1
WO1984000105A1 PCT/SU1982/000020 SU8200020W WO8400105A1 WO 1984000105 A1 WO1984000105 A1 WO 1984000105A1 SU 8200020 W SU8200020 W SU 8200020W WO 8400105 A1 WO8400105 A1 WO 8400105A1
Authority
WO
WIPO (PCT)
Prior art keywords
product
medicinal preparation
antitumoral effect
proposed
pharmaceutical product
Prior art date
Application number
PCT/SU1982/000020
Other languages
English (en)
Russian (ru)
Inventor
Inta Zhanovna Lulle
Margeris Jurievich Lidak
Ruta Albertovna Paegle
Aina Avgustovna Zidermane
Iya Mikhailovna Kravchenko
Anatoly Pavlovich Gilev
Tamara Iosifovna Kagan
Petr Alexandrovich Gembitsky
Boris Zalmanovich Simkhovich
Original Assignee
Inst Organicheskogo Sinteza Ak
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Organicheskogo Sinteza Ak filed Critical Inst Organicheskogo Sinteza Ak
Priority to JP57503491A priority Critical patent/JPS59501110A/ja
Priority to PCT/SU1982/000020 priority patent/WO1984000105A1/fr
Priority to CH90284A priority patent/CH660964A5/de
Priority to DE19823249514 priority patent/DE3249514T1/de
Priority to GB08403257A priority patent/GB2134783B/en
Priority to NL8220420A priority patent/NL8220420A/nl
Priority to CA000413032A priority patent/CA1194802A/fr
Priority to FR8218494A priority patent/FR2535609A1/fr
Publication of WO1984000105A1 publication Critical patent/WO1984000105A1/fr
Priority to SE8400453A priority patent/SE8400453L/

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Definitions

  • the task was ⁇ eshena ⁇ em, ch ⁇ le ⁇ a ⁇ s ⁇ venny ⁇ e ⁇ a- ⁇ a ⁇ ⁇ iv ⁇ u ⁇ lev ⁇ g ⁇ deys ⁇ viya, s ⁇ de ⁇ zhaschy deys ⁇ vuyu- present vesches ⁇ v ⁇ and ⁇ a ⁇ matsev ⁇ iches ⁇ y ⁇ azbavi ⁇ el, s ⁇ glasn ⁇ iz ⁇ b ⁇ e ⁇ eniyu in ⁇ aches ⁇ deys ⁇ vuscheg ⁇ vesches ⁇ va s ⁇ de ⁇ zhi ⁇ ⁇ s ⁇ a ⁇ ⁇ lige ⁇ same ⁇ ilenguanidina you next ⁇ tsuly
  • the sensitivity of the _- was studied: oleochki kletotok, ⁇ Ya-tytykh ⁇ at the same time in 22 home-friendly, it is easy to handle.
  • This concentration will cause the ⁇ * ⁇ ⁇ a + ions to be squeezed out of the cell into the non-cellular fluid.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

La préparation médicinale ayant un effet antitumoral consiste en une substance active telle la guanidine de polyhexaméthylène, de formule (I):$(7,)$et contient un diluant pharmaceutique.
PCT/SU1982/000020 1982-06-21 1982-06-21 Preparation medicinale ayant un effet antitumoral WO1984000105A1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP57503491A JPS59501110A (ja) 1982-06-21 1982-06-21 抗腫瘍活性を有する薬剤組成物
PCT/SU1982/000020 WO1984000105A1 (fr) 1982-06-21 1982-06-21 Preparation medicinale ayant un effet antitumoral
CH90284A CH660964A5 (de) 1982-06-21 1982-06-21 Arzneimittelpraeparat mit antikarzinogener wirkung.
DE19823249514 DE3249514T1 (de) 1982-06-21 1982-06-21 Arzneimittel mit antikarzinogener Wirkung
GB08403257A GB2134783B (en) 1982-06-21 1982-06-21 Medical preparation having antitumoral effect
NL8220420A NL8220420A (nl) 1982-06-21 1982-06-21 Farmaceutische samenstelling, die antitumoractiviteit bezit.
CA000413032A CA1194802A (fr) 1982-06-21 1982-10-07 Compose pharmaceutique antitumoral
FR8218494A FR2535609A1 (fr) 1982-06-21 1982-11-04 Medicament a action antitumorale a base de polyhexamethyleneguanidine
SE8400453A SE8400453L (sv) 1982-06-21 1984-01-30 Lekemedelspreparat med antitumorverkan

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SU1982/000020 WO1984000105A1 (fr) 1982-06-21 1982-06-21 Preparation medicinale ayant un effet antitumoral

Publications (1)

Publication Number Publication Date
WO1984000105A1 true WO1984000105A1 (fr) 1984-01-19

Family

ID=21616776

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SU1982/000020 WO1984000105A1 (fr) 1982-06-21 1982-06-21 Preparation medicinale ayant un effet antitumoral

Country Status (9)

Country Link
JP (1) JPS59501110A (fr)
CA (1) CA1194802A (fr)
CH (1) CH660964A5 (fr)
DE (1) DE3249514T1 (fr)
FR (1) FR2535609A1 (fr)
GB (1) GB2134783B (fr)
NL (1) NL8220420A (fr)
SE (1) SE8400453L (fr)
WO (1) WO1984000105A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994015596A1 (fr) * 1992-12-30 1994-07-21 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Compositions et procedes permettant d'inhiber la desoxyhypusine-synthase et la croissance cellulaire

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19628641C2 (de) * 1996-07-16 1998-12-17 Fresenius Ag Verwendung von PHMB zur Behandlung von Tumorerkrankungen
KR100557559B1 (ko) * 1999-12-20 2006-03-03 에스케이 주식회사 폴리헥사메틸렌구아니딘 인산염 분말, 이의 제조방법 및이를 함유한 항균수지
KR100725004B1 (ko) * 1999-12-24 2007-06-04 에스케이 주식회사 살균소독제 조성물 및 이의 사용방법
AT505312A1 (de) 2007-05-15 2008-12-15 Recticel Schlafkomfort Gmbh Sc Polyurethan-werkstoff mit einer bioziden ausrüstung

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1040049A (en) * 1963-12-23 1966-08-24 Rohm & Haas Preparation of tertiary octylguanidines
US3824288A (en) * 1961-06-09 1974-07-16 Hoffmann La Roche Substituted hydrazine derivatives and process for the manufacture thereof
GB1492678A (en) * 1975-08-11 1977-11-23 Ici Ltd Guanidine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5341426A (en) * 1976-09-27 1978-04-14 Asahi Chem Ind Co Ltd Fungicidal and bactericidal agents

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3824288A (en) * 1961-06-09 1974-07-16 Hoffmann La Roche Substituted hydrazine derivatives and process for the manufacture thereof
GB1040049A (en) * 1963-12-23 1966-08-24 Rohm & Haas Preparation of tertiary octylguanidines
GB1492678A (en) * 1975-08-11 1977-11-23 Ici Ltd Guanidine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994015596A1 (fr) * 1992-12-30 1994-07-21 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Compositions et procedes permettant d'inhiber la desoxyhypusine-synthase et la croissance cellulaire

Also Published As

Publication number Publication date
SE437931B (sv) 1985-03-25
GB8403257D0 (en) 1984-03-14
GB2134783A (en) 1984-08-22
DE3249514T1 (de) 1984-05-17
CH660964A5 (de) 1987-06-30
NL8220420A (nl) 1984-05-01
FR2535609B1 (fr) 1985-03-15
SE8400453D0 (sv) 1984-01-30
JPS59501110A (ja) 1984-06-28
CA1194802A (fr) 1985-10-08
GB2134783B (en) 1985-10-30
FR2535609A1 (fr) 1984-05-11
SE8400453L (sv) 1985-03-25

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