GB1040049A - Preparation of tertiary octylguanidines - Google Patents
Preparation of tertiary octylguanidinesInfo
- Publication number
- GB1040049A GB1040049A GB1215864A GB1215864A GB1040049A GB 1040049 A GB1040049 A GB 1040049A GB 1215864 A GB1215864 A GB 1215864A GB 1215864 A GB1215864 A GB 1215864A GB 1040049 A GB1040049 A GB 1040049A
- Authority
- GB
- United Kingdom
- Prior art keywords
- guanidines
- octylguanidines
- tertiary
- preparation
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Guanidines of the formula t-Octyl-NH-C(:NH)NHR and acid addition salts thereof, wherein R is H or CH3 and the t-octyl group is such that the C atom attached to the N atom does not carry an H atom are prepared by reacting t-octyl cyanamide with an amine R.NH2. The guanidines of the invention are hypotensive agents and may be made up in a form suitable for enteral or parenteral administration. The guanidines are also fungicidal agents.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33295163A | 1963-12-23 | 1963-12-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1040049A true GB1040049A (en) | 1966-08-24 |
Family
ID=23300597
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1215864A Expired GB1040049A (en) | 1963-12-23 | 1964-03-23 | Preparation of tertiary octylguanidines |
Country Status (4)
Country | Link |
---|---|
BE (1) | BE645940A (en) |
BR (1) | BR6457241D0 (en) |
GB (1) | GB1040049A (en) |
NL (1) | NL6402844A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984000105A1 (en) * | 1982-06-21 | 1984-01-19 | Inst Organicheskogo Sinteza Ak | Medicinal preparation having antitumoral effect |
EP1434761B1 (en) * | 2001-10-10 | 2010-02-24 | Biosphings Aktiengesellschaft | Salts of guanidine derivatives and pharmaceutical preparations consisting thereof |
-
1964
- 1964-03-02 BR BR15724164A patent/BR6457241D0/en unknown
- 1964-03-17 NL NL6402844A patent/NL6402844A/xx unknown
- 1964-03-23 GB GB1215864A patent/GB1040049A/en not_active Expired
- 1964-03-31 BE BE645940D patent/BE645940A/xx unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984000105A1 (en) * | 1982-06-21 | 1984-01-19 | Inst Organicheskogo Sinteza Ak | Medicinal preparation having antitumoral effect |
EP1434761B1 (en) * | 2001-10-10 | 2010-02-24 | Biosphings Aktiengesellschaft | Salts of guanidine derivatives and pharmaceutical preparations consisting thereof |
Also Published As
Publication number | Publication date |
---|---|
BE645940A (en) | 1964-09-30 |
BR6457241D0 (en) | 1973-06-26 |
NL6402844A (en) | 1965-06-24 |
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