GB947001A - Substituted phenoxyalklylguanidines - Google Patents
Substituted phenoxyalklylguanidinesInfo
- Publication number
- GB947001A GB947001A GB45125/61A GB4512561A GB947001A GB 947001 A GB947001 A GB 947001A GB 45125/61 A GB45125/61 A GB 45125/61A GB 4512561 A GB4512561 A GB 4512561A GB 947001 A GB947001 A GB 947001A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- acid addition
- halogen
- reacting
- nitrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/08—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compounds of general formula: <FORM:0947001/C2/1> wherein n is a whole number from 2 to 5 inclusive, R is halogen, and R1 is hydrogen or halogen; and their acid addition salts; and their preparation by (1) reacting a compound <FORM:0947001/C2/2> with an acid addition salt of a compound <FORM:0947001/C2/3> wherein z is a hydrocarbonthio or hydrocarbonoxy radical, or an unsubstituted, mono or poly-substituted unsaturated nitrogen heterocyclic radical containing at leasr two nitrogen atoms in its ring system and connected to the amidine carbon atom through nitrogen, or (2) reacting a compound II or an acid addition salt thereof with cyanamide or dicyanamide. The compounds which have antihypertensive and antibacterial activity, may be administered orally or parenterally.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8097561A | 1961-01-06 | 1961-01-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB947001A true GB947001A (en) | 1964-01-22 |
Family
ID=22160873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB45125/61A Expired GB947001A (en) | 1961-01-06 | 1961-12-15 | Substituted phenoxyalklylguanidines |
Country Status (2)
Country | Link |
---|---|
FR (2) | FR1431656A (en) |
GB (1) | GB947001A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3474134A (en) * | 1960-03-03 | 1969-10-21 | Burroughs Wellcome Co | Phenoxyethyl-guanidines and the salts thereof |
-
1961
- 1961-12-15 GB GB45125/61A patent/GB947001A/en not_active Expired
-
1962
- 1962-01-05 FR FR883980A patent/FR1431656A/en not_active Expired
- 1962-03-26 FR FR892222A patent/FR1788M/en active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3474134A (en) * | 1960-03-03 | 1969-10-21 | Burroughs Wellcome Co | Phenoxyethyl-guanidines and the salts thereof |
Also Published As
Publication number | Publication date |
---|---|
FR1788M (en) | 1963-04-22 |
FR1431656A (en) | 1966-03-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES342185A1 (en) | N,n'-diglycidyl hydantoins | |
GB1409768A (en) | Hererocyclic derivatives of a guanidine | |
GB1016071A (en) | New guanidine derivatives and process for preparing the same | |
GB1250971A (en) | ||
ES273438A1 (en) | Phenoxypropylguanidine compounds | |
GB947001A (en) | Substituted phenoxyalklylguanidines | |
GB1050554A (en) | ||
GB1507414A (en) | Hydantoin derivatives | |
GB1375378A (en) | ||
GB1318859A (en) | Imidazo-4,5-b-pyridine derivatives | |
ES392819A1 (en) | M-(amino-s-triazolyl)benzene-sulfonamides and their production | |
GB959993A (en) | Camphor derivatives | |
GB1299566A (en) | Bis-basic ethers of 2,6- and 2,7-dihydroxyanthraquinones | |
GB1017264A (en) | Quinazolinone derivatives and the manufacture thereof | |
ES451375A1 (en) | 2,4-diamino-5-benzylpyrimidines | |
GB1325944A (en) | Bisoxalic acid diamides | |
GB1040049A (en) | Preparation of tertiary octylguanidines | |
GB981536A (en) | Process for the preparation of 2,4-diamino-6-cyano-triazines | |
GB1017450A (en) | 2-amino-4-alkoxy-úË-triazines | |
GB1298020A (en) | 3-halo-2,6-dinitro-4-trifluoromethylanilines | |
GB1005023A (en) | Preparation of naphthalene derivatives | |
GB878603A (en) | Salicyclic acid derivatives | |
CH613942A5 (en) | Process for the preparation of non-toxic acid addition salts of guanidine compounds | |
GB1219249A (en) | Pyrimidopyrimidine derivatives | |
GB1032268A (en) | New guanyl-hydrazones and preparations containing them |