GB1362389A - Pharmaceutical preparations containing certain guanidine compounds - Google Patents
Pharmaceutical preparations containing certain guanidine compoundsInfo
- Publication number
- GB1362389A GB1362389A GB4153571A GB4153571A GB1362389A GB 1362389 A GB1362389 A GB 1362389A GB 4153571 A GB4153571 A GB 4153571A GB 4153571 A GB4153571 A GB 4153571A GB 1362389 A GB1362389 A GB 1362389A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pharmaceutical preparations
- guanidines
- preparations containing
- containing certain
- guanidine compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1362389 Guanidines ARMOUR PHARMACEUTICAL CO 6 Sept 1971 [10 Nov 1970] 41535/71 Heading C2C [Also in Division A5] Guanidines (some of which are novel) of the Formula I (in which R 1 is H or C 1-4 alkyl, R 2 is H, OH, Cl, F or Br, or R 1 and R 2 are joined to form a benzo group, R 3 is H, CH 3 CO, Cl, Br, F or OH, and R 4 is H, Cl, Br or F, provided that when R 4 is Cl, Br or F, R 2 is the same, and R 3 is other than OH, and provided that the number of OH groups is never greater than one) are prepared by reacting cyanamide with an appropriate amine or mineral acid addition salt thereof, or by reacting an appropriate 1-aryl-2-methyl-2- thiopseudourea hydroiodide, ammonia and ethanol. The guanidines may be converted to their acid addition salts. Compounds I have vasoconstrictor properties and may be formulated into pharmaceutical preparations.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8850170A | 1970-11-10 | 1970-11-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1362389A true GB1362389A (en) | 1974-08-07 |
Family
ID=22211736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4153571A Expired GB1362389A (en) | 1970-11-10 | 1971-09-06 | Pharmaceutical preparations containing certain guanidine compounds |
Country Status (3)
Country | Link |
---|---|
DE (1) | DE2144583A1 (en) |
FR (1) | FR2113916B1 (en) |
GB (1) | GB1362389A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5733932A (en) * | 1995-01-06 | 1998-03-31 | The Picower Institute For Medical Research | Compounds and methods of use to derivatize neighboring lysine residues in proteins under physiological conditions |
-
1971
- 1971-09-06 DE DE19712144583 patent/DE2144583A1/en active Pending
- 1971-09-06 GB GB4153571A patent/GB1362389A/en not_active Expired
- 1971-11-10 FR FR7140386A patent/FR2113916B1/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2144583A1 (en) | 1972-05-18 |
FR2113916A1 (en) | 1972-06-30 |
FR2113916B1 (en) | 1975-03-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |