GB1362389A - Pharmaceutical preparations containing certain guanidine compounds - Google Patents

Pharmaceutical preparations containing certain guanidine compounds

Info

Publication number
GB1362389A
GB1362389A GB4153571A GB4153571A GB1362389A GB 1362389 A GB1362389 A GB 1362389A GB 4153571 A GB4153571 A GB 4153571A GB 4153571 A GB4153571 A GB 4153571A GB 1362389 A GB1362389 A GB 1362389A
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical preparations
guanidines
preparations containing
containing certain
guanidine compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4153571A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Armour Pharmaceutical Co
Original Assignee
Armour Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Armour Pharmaceutical Co filed Critical Armour Pharmaceutical Co
Publication of GB1362389A publication Critical patent/GB1362389A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1362389 Guanidines ARMOUR PHARMACEUTICAL CO 6 Sept 1971 [10 Nov 1970] 41535/71 Heading C2C [Also in Division A5] Guanidines (some of which are novel) of the Formula I (in which R 1 is H or C 1-4 alkyl, R 2 is H, OH, Cl, F or Br, or R 1 and R 2 are joined to form a benzo group, R 3 is H, CH 3 CO, Cl, Br, F or OH, and R 4 is H, Cl, Br or F, provided that when R 4 is Cl, Br or F, R 2 is the same, and R 3 is other than OH, and provided that the number of OH groups is never greater than one) are prepared by reacting cyanamide with an appropriate amine or mineral acid addition salt thereof, or by reacting an appropriate 1-aryl-2-methyl-2- thiopseudourea hydroiodide, ammonia and ethanol. The guanidines may be converted to their acid addition salts. Compounds I have vasoconstrictor properties and may be formulated into pharmaceutical preparations.
GB4153571A 1970-11-10 1971-09-06 Pharmaceutical preparations containing certain guanidine compounds Expired GB1362389A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8850170A 1970-11-10 1970-11-10

Publications (1)

Publication Number Publication Date
GB1362389A true GB1362389A (en) 1974-08-07

Family

ID=22211736

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4153571A Expired GB1362389A (en) 1970-11-10 1971-09-06 Pharmaceutical preparations containing certain guanidine compounds

Country Status (3)

Country Link
DE (1) DE2144583A1 (en)
FR (1) FR2113916B1 (en)
GB (1) GB1362389A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733932A (en) * 1995-01-06 1998-03-31 The Picower Institute For Medical Research Compounds and methods of use to derivatize neighboring lysine residues in proteins under physiological conditions

Also Published As

Publication number Publication date
FR2113916A1 (en) 1972-06-30
DE2144583A1 (en) 1972-05-18
FR2113916B1 (en) 1975-03-14

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees