UY35272A - ?antígenos recombinantes del porcine circovirus 2 (pcv-2) para formulaciones de vacuna, kit de diagnóstico y uso?. - Google Patents

?antígenos recombinantes del porcine circovirus 2 (pcv-2) para formulaciones de vacuna, kit de diagnóstico y uso?.

Info

Publication number
UY35272A
UY35272A UY0001035272A UY35272A UY35272A UY 35272 A UY35272 A UY 35272A UY 0001035272 A UY0001035272 A UY 0001035272A UY 35272 A UY35272 A UY 35272A UY 35272 A UY35272 A UY 35272A
Authority
UY
Uruguay
Prior art keywords
pcv
vaccine formulations
circovirus
swine
vaccines
Prior art date
Application number
UY0001035272A
Other languages
English (en)
Inventor
Márcia Rogéria De Almeida Lamego
Abelardo Silva Júnior
Juliana Lopes Rangel Fietto
Gustavo Costa Bressan
Rafael Locatelli Salgado
Thiago Souza Onofre
Mariana Costa Fausto
Pedro Marcus Pereira Vidigal
Sthefany Patareli Kalks
Josicelli Souza Crispim
Original Assignee
Fundaç O De Amparo Pesquisa De Minas Gerais Fapemig
Univ Fed De Viçosa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundaç O De Amparo Pesquisa De Minas Gerais Fapemig, Univ Fed De Viçosa filed Critical Fundaç O De Amparo Pesquisa De Minas Gerais Fapemig
Publication of UY35272A publication Critical patent/UY35272A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10023—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/015—Parvoviridae, e.g. feline panleukopenia virus, human Parvovirus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)

Abstract

Obtención de antígeno recombinante de la cápside viral de Porcine circovirus 2 y modificaciones, por expresión en sistema procarionte, purificación en forma monomérica, recuperación de partícula similar a virus (VLP), uso en vacunas, kits de diagnóstico, sistema de cuantificación de lotes de vacuna del antígeno del PVC-2 por ELISA de captura. Antígenos y formulaciones de vacuna pueden usarse en inmunización de animales en programas de control de enfermedades asociadas con PCV-2 en sistemas de producción de porcinos y representan alternativas a vacunas disponibles. El kit de ELISA puede usarse para pruebas de calidad en vacunas comerciales y/o experimentales contra PCV-2.
UY0001035272A 2013-01-25 2014-01-20 ?antígenos recombinantes del porcine circovirus 2 (pcv-2) para formulaciones de vacuna, kit de diagnóstico y uso?. UY35272A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR102013001893-7A BR102013001893B1 (pt) 2013-01-25 2013-01-25 Antígenos recombinantes do porcine circovirus 2 (pcv-2) para formulações vacinais, kit de diagnóstico e uso

Publications (1)

Publication Number Publication Date
UY35272A true UY35272A (es) 2014-08-29

Family

ID=51226766

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001035272A UY35272A (es) 2013-01-25 2014-01-20 ?antígenos recombinantes del porcine circovirus 2 (pcv-2) para formulaciones de vacuna, kit de diagnóstico y uso?.

Country Status (11)

Country Link
US (2) US9717785B2 (es)
EP (1) EP2949341B1 (es)
CN (1) CN105263515A (es)
AR (1) AR094578A1 (es)
BR (1) BR102013001893B1 (es)
CO (1) CO7461131A2 (es)
ES (1) ES2792510T3 (es)
MX (1) MX362820B (es)
RU (1) RU2687001C2 (es)
UY (1) UY35272A (es)
WO (1) WO2014113855A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106478783B (zh) * 2015-08-24 2021-11-02 兆丰华生物科技(南京)有限公司北京生物医药科技中心 一种猪圆环病毒ii型基因工程亚单位疫苗及其应用
CN105541976B (zh) * 2015-12-25 2019-07-09 华南农业大学 猪圆环病毒2型Cap基因修饰改造重组抗原及其应用
CN109425738B (zh) * 2017-09-01 2022-01-28 洛阳普泰生物技术有限公司 猪圆环病毒3型抗体检测试剂盒及其应用
CN109187774B (zh) * 2018-07-03 2021-09-28 复旦大学 一种猪圆环病毒2型病毒样颗粒的定量检测方法
CN110981945B (zh) * 2019-12-08 2021-10-19 中牧实业股份有限公司 一种猪圆环病毒2型重组Cap蛋白的表达制备及应用
CN111233983A (zh) * 2020-02-26 2020-06-05 郭广君 猪圆环病毒cap蛋白一步法大规模纯化及内毒素去除工艺
CN114354526A (zh) * 2021-12-28 2022-04-15 国药集团动物保健股份有限公司 一种猪圆环病毒3型纯品蛋白的定量检测方法
CN114805501B (zh) * 2022-03-24 2024-06-25 中牧实业股份有限公司 一种猪圆环病毒2型抗原组合物及其在抗原定量方法中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2769322B1 (fr) * 1997-10-03 2002-03-08 Merial Sas Nouveaux circovirus porcins, vaccins et reactifs de diagnostic
US6287856B1 (en) 1998-03-13 2001-09-11 University Of Georgia Research Foundation, Inc. Vaccines against circovirus infections
RU2354399C2 (ru) 2003-07-24 2009-05-10 Мериал Лимитед Вакцинная композиция и способ индуцирования иммунологического ответа у животного
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
ES2425228T3 (es) 2005-09-09 2013-10-14 Intervet International B.V. Vacuna contra el PCV-2
BR122015028489B1 (pt) 2005-12-29 2021-10-13 Boehringer Ingelheim Animal Health Usa Inc Vacina de combinação multivalente contra pcv2, bem como uso de uma proteína orf2 na preparação da mesma
ME01156B (me) * 2007-12-21 2013-03-20 Zoetis Services Llc Postupci i kompozicije za imunizaciju svinja protiv svinjskog cirkovirusa
EP2367933A1 (en) * 2008-11-28 2011-09-28 Ceva Sante Animale Novel porcine circovirus type 2b isolate and uses thereof
CN102711816A (zh) * 2009-10-22 2012-10-03 莱比锡大学 患有牛新生儿全血细胞减少症的小牛中的圆环病毒的检测
CN102174086B (zh) * 2011-03-07 2014-04-02 南京农业大学 一种猪圆环病毒2型重组Cap蛋白和亚单位疫苗
CN102911947A (zh) * 2011-08-01 2013-02-06 普莱柯生物工程股份有限公司 猪圆环病毒2型Cap蛋白及其制备方法
CN102839195A (zh) * 2012-07-18 2012-12-26 华南农业大学 利用pFast Bac Dual杆状病毒表达PCV 2 Cap蛋白的方法

Also Published As

Publication number Publication date
RU2687001C2 (ru) 2019-05-06
EP2949341A1 (en) 2015-12-02
US20160015799A1 (en) 2016-01-21
BR102013001893B1 (pt) 2022-01-25
BR102013001893A8 (pt) 2017-12-05
MX2015009507A (es) 2016-04-07
BR102013001893A2 (pt) 2014-09-09
WO2014113855A1 (pt) 2014-07-31
RU2015135619A (ru) 2017-03-10
US9717785B2 (en) 2017-08-01
MX362820B (es) 2019-02-18
CO7461131A2 (es) 2015-11-30
AR094578A1 (es) 2015-08-12
ES2792510T3 (es) 2020-11-11
US20160000897A1 (en) 2016-01-07
EP2949341B1 (en) 2020-04-01
CN105263515A (zh) 2016-01-20
EP2949341A4 (en) 2016-07-27

Similar Documents

Publication Publication Date Title
UY35272A (es) ?antígenos recombinantes del porcine circovirus 2 (pcv-2) para formulaciones de vacuna, kit de diagnóstico y uso?.
CL2019000067A1 (es) Anticuerpos nuevos que se unen específicamente a los epítopos del virus del zika y usos de los mismos.
BR112018012873A2 (pt) vacina de vírus zika
EA201800494A1 (ru) Вакцины против химерного цирковируса свиней типа 2 (pcv2)
PE20171133A1 (es) Particulas tipo virus modificadas de cmv
EA201600305A1 (ru) Вариант белка opc2 pcv2 и содержащие его вирусоподобные частицы
MX2020010248A (es) Variante del virus prrs, clon de adnc del virus europeo y sus usos.
NZ741875A (en) Canine parvovirus (cpv) virus-like particle (vlp) vaccines and uses thereof
PH12014502534A1 (en) Effective vaccination against porcine reproductive and respiratory syndrome (prrs) virus prior to weaning
WO2014150822A3 (en) Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
BR112018075513A2 (pt) ácidos nucleicos que codificam as partículas seme-lhantes ao vírus da zika e seu uso nas vacinas e no ensaio de diagnóstico do vírus da zika
MX2015007723A (es) PARVOVIRUS PORCINO 5ª, METODOS DE USO Y VACUNA.
NZ731659A (en) Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus
MY179251A (en) Methods and compositions for recombinant dengue viruses for vaccine and diagnostic development
PH12018502436A1 (en) Multivalent vaccines major swine viral diseases
HRP20171697T1 (hr) Varijanta hiv gp-120
MY181007A (en) Scale drop disease (sdd) causative virus and derivatives thereof
MX366263B (es) Parvovirus porcino 5b, metodos de uso y vacuna.
PH12017501100A1 (en) Recombinant swinepox virus and vaccines
PH12014501795A1 (en) Rota virus subunit vaccines and methods of making and use thereof
EA201790365A1 (ru) Антигены вируса папилломы человека с хорошими иммунологическими свойствами и содержащая их вакцина
WO2018066999A3 (en) Chimeric enterovirus virus-like particles
BR112015023738B8 (pt) Vacinas de nucleoproteina influenza
EA201592298A1 (ru) Полуживая вирусная вакцина против респираторно-синцитиального вируса
EA201500140A1 (ru) Ослабленные вакцины от свиного гриппа и способы их получения и применения

Legal Events

Date Code Title Description
110 Patent granted

Effective date: 20220721