UY31071A1 - Derivados heterociclicos sustituidos y su uso farmaceutico y composiciones - Google Patents

Derivados heterociclicos sustituidos y su uso farmaceutico y composiciones

Info

Publication number
UY31071A1
UY31071A1 UY31071A UY31071A UY31071A1 UY 31071 A1 UY31071 A1 UY 31071A1 UY 31071 A UY31071 A UY 31071A UY 31071 A UY31071 A UY 31071A UY 31071 A1 UY31071 A1 UY 31071A1
Authority
UY
Uruguay
Prior art keywords
compositions
replaced
pharmaceutical use
heterociclic
derivatives
Prior art date
Application number
UY31071A
Other languages
English (en)
Spanish (es)
Inventor
Zhijun Zhang
Chakrapani Subramanyam
Shaugnessy Robinson
Michael Aaron Plotkin
Usa Reilly
Mark-Joseph Mitton Fry
Anthony Marfat
Zhengong Bryan Li
Jinshan Michael Chen
Steven Joseph Brickner
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of UY31071A1 publication Critical patent/UY31071A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
UY31071A 2007-05-09 2008-05-08 Derivados heterociclicos sustituidos y su uso farmaceutico y composiciones UY31071A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91690607P 2007-05-09 2007-05-09

Publications (1)

Publication Number Publication Date
UY31071A1 true UY31071A1 (es) 2009-01-05

Family

ID=39865577

Family Applications (1)

Application Number Title Priority Date Filing Date
UY31071A UY31071A1 (es) 2007-05-09 2008-05-08 Derivados heterociclicos sustituidos y su uso farmaceutico y composiciones

Country Status (17)

Country Link
US (3) US20080280879A1 (enExample)
EP (2) EP2481735A1 (enExample)
JP (1) JP2010526130A (enExample)
KR (2) KR20090130347A (enExample)
CN (1) CN101679357A (enExample)
AR (1) AR066478A1 (enExample)
AU (1) AU2008249745B2 (enExample)
CA (1) CA2685888A1 (enExample)
CL (1) CL2008001367A1 (enExample)
IL (1) IL201830A0 (enExample)
MX (1) MX2009012117A (enExample)
PA (1) PA8779801A1 (enExample)
PE (1) PE20090240A1 (enExample)
TW (1) TW200902518A (enExample)
UY (1) UY31071A1 (enExample)
WO (1) WO2008139288A2 (enExample)
ZA (1) ZA200907761B (enExample)

Families Citing this family (18)

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WO2011006621A1 (en) * 2009-07-11 2011-01-20 Bayer Schering Pharma Aktiengesellschaft Radiolabelling method using cycloalkyl groups
MA41169A (fr) 2014-12-17 2017-10-24 Acraf Composés antibactériens à large spectre d'activité
SMT202000335T1 (it) 2016-06-08 2020-07-08 Acraf Nuovi composti antibatterici
JP6755775B2 (ja) * 2016-11-04 2020-09-16 富士アミドケミカル株式会社 ４−フルオロイソキノリンの製法
CN108627579B (zh) * 2017-03-24 2020-12-01 上海安谱实验科技股份有限公司 Pbt制品中多环芳烃的提取方法
EA202091588A1 (ru) * 2017-12-26 2021-01-18 Сайтокинетикс, Инкорпорейтид Способ получения аминопиримидина и его промежуточных продуктов
BR112021008741A2 (pt) 2018-11-09 2021-08-10 Vivace Therapeutics, Inc. compostos bicíclicos
CN114072207B (zh) 2019-04-16 2024-03-29 维瓦斯治疗公司 双环化合物
CN111848423B (zh) * 2019-04-30 2022-10-14 尚科生物医药（上海）有限公司 3-氧代环丁基氨基甲酸叔丁酯的制备方法
WO2021257857A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Naphthyridinone compounds as jak2 v617f inhibitors
WO2021257863A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Pyrrolotriazine compounds as jak2 v617f inhibitors
WO2022006456A1 (en) 2020-07-02 2022-01-06 Incyte Corporation Tricyclic pyridone compounds as jak2 v617f inhibitors
SMT202500271T1 (it) 2020-07-02 2025-09-12 Incyte Corp Composti di urea triciclici come inibitori di v617f di jak2
WO2022046989A1 (en) 2020-08-27 2022-03-03 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors
US11919908B2 (en) 2020-12-21 2024-03-05 Incyte Corporation Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors
TW202302589A (zh) 2021-02-25 2023-01-16 美商英塞特公司 作為ｊａｋ２ ｖ６１７ｆ抑制劑之螺環內醯胺
TW202334089A (zh) 2021-11-02 2023-09-01 美商夫雷爾醫療公司 Ｐｐａｒｇ反向激動劑及其用途
MX2024011378A (es) 2022-03-17 2024-09-23 Incyte Corp Compuestos de urea triciclica como inhibidores de la variante v617f de la cinasa de janus 2 (jak2).

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Also Published As

Publication number Publication date
WO2008139288A2 (en) 2008-11-20
CN101679357A (zh) 2010-03-24
US20120065188A1 (en) 2012-03-15
AU2008249745B2 (en) 2012-01-12
IL201830A0 (en) 2010-06-16
MX2009012117A (es) 2009-11-23
TW200902518A (en) 2009-01-16
WO2008139288A3 (en) 2009-03-26
US20080280879A1 (en) 2008-11-13
PA8779801A1 (es) 2009-01-23
KR20120011093A (ko) 2012-02-06
PE20090240A1 (es) 2009-03-19
CA2685888A1 (en) 2008-11-20
US20110092480A1 (en) 2011-04-21
KR20090130347A (ko) 2009-12-22
ZA200907761B (en) 2010-08-25
AR066478A1 (es) 2009-08-19
EP2155716A2 (en) 2010-02-24
CL2008001367A1 (es) 2008-11-07
JP2010526130A (ja) 2010-07-29
AU2008249745A1 (en) 2008-11-20
EP2481735A1 (en) 2012-08-01

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Effective date: 20171005