UY29058A1 - Compuestos de isoindolona y su uso como potenciadores del receptor metabotropico de glutamato - Google Patents

Compuestos de isoindolona y su uso como potenciadores del receptor metabotropico de glutamato

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Publication number
UY29058A1
UY29058A1 UY29058A UY29058A UY29058A1 UY 29058 A1 UY29058 A1 UY 29058A1 UY 29058 A UY29058 A UY 29058A UY 29058 A UY29058 A UY 29058A UY 29058 A1 UY29058 A1 UY 29058A1
Authority
UY
Uruguay
Prior art keywords
potenciators
metabotropic glutamate
compounds
isoindolone compounds
receiver
Prior art date
Application number
UY29058A
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English (en)
Inventor
Bradford Van Wagenen
Radhakrishnan Ukkiramapandian
Joshua Clayton
Ian Egle
James Empfield
Methvin Isaac
Fupeng Ma
Abdelmalik Slassi
Gary Steelman
Sally Walsh
Rebecca Urbanek
Original Assignee
Astrazeneca Ab
Nps Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35428151&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY29058(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab, Nps Pharma Inc filed Critical Astrazeneca Ab
Publication of UY29058A1 publication Critical patent/UY29058A1/es

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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Abstract

Compuestos de fórmula I: en donde R1,R2,R3,R4,R5,R6,R7,R8, R9 y n tienen los valores definidos para la fórmula I en la memoria descriptiva. También se describen procesos para la preparación de los compuestos y nuevos intermediarios empleados en la preparación, composiciones farmacéuticas que contienen los compuestos y uso terapéutico de los mismos.
UY29058A 2004-08-13 2005-08-11 Compuestos de isoindolona y su uso como potenciadores del receptor metabotropico de glutamato UY29058A1 (es)

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US60112504P 2004-08-13 2004-08-13
US68494505P 2005-05-27 2005-05-27

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UY29058A1 true UY29058A1 (es) 2006-02-24

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