MX2009012117A - Composiciones y derivados heterociclicos sustituidos y su uso farmaceutico como antibacterianos. - Google Patents

Composiciones y derivados heterociclicos sustituidos y su uso farmaceutico como antibacterianos.

Info

Publication number
MX2009012117A
MX2009012117A MX2009012117A MX2009012117A MX2009012117A MX 2009012117 A MX2009012117 A MX 2009012117A MX 2009012117 A MX2009012117 A MX 2009012117A MX 2009012117 A MX2009012117 A MX 2009012117A MX 2009012117 A MX2009012117 A MX 2009012117A
Authority
MX
Mexico
Prior art keywords
antibacterials
compositions
substituted heterocyclic
pharmaceutical use
heterocyclic derivatives
Prior art date
Application number
MX2009012117A
Other languages
English (en)
Spanish (es)
Inventor
Anthony Marfat
Zhengong Bryan Li
Usa Reilly
Steven Joseph Brickner
Jinshan Michael Chen
Mark Joseph Mitton-Fry
Michael Aaron Plotkin
Shaughnessy Robinson
Chakrapani Subramanyam
Zhijun Zhang
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX2009012117A publication Critical patent/MX2009012117A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX2009012117A 2007-05-09 2008-04-29 Composiciones y derivados heterociclicos sustituidos y su uso farmaceutico como antibacterianos. MX2009012117A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91690607P 2007-05-09 2007-05-09
PCT/IB2008/001076 WO2008139288A2 (en) 2007-05-09 2008-04-29 Substituted heterocyclic derivatives and compositions and their pharmaceutical use as antibacterials

Publications (1)

Publication Number Publication Date
MX2009012117A true MX2009012117A (es) 2009-11-23

Family

ID=39865577

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012117A MX2009012117A (es) 2007-05-09 2008-04-29 Composiciones y derivados heterociclicos sustituidos y su uso farmaceutico como antibacterianos.

Country Status (17)

Country Link
US (3) US20080280879A1 (enExample)
EP (2) EP2481735A1 (enExample)
JP (1) JP2010526130A (enExample)
KR (2) KR20090130347A (enExample)
CN (1) CN101679357A (enExample)
AR (1) AR066478A1 (enExample)
AU (1) AU2008249745B2 (enExample)
CA (1) CA2685888A1 (enExample)
CL (1) CL2008001367A1 (enExample)
IL (1) IL201830A0 (enExample)
MX (1) MX2009012117A (enExample)
PA (1) PA8779801A1 (enExample)
PE (1) PE20090240A1 (enExample)
TW (1) TW200902518A (enExample)
UY (1) UY31071A1 (enExample)
WO (1) WO2008139288A2 (enExample)
ZA (1) ZA200907761B (enExample)

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MA41169A (fr) 2014-12-17 2017-10-24 Acraf Composés antibactériens à large spectre d'activité
AU2017276627A1 (en) 2016-06-08 2018-12-20 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. New antibacterial compounds
JP6755775B2 (ja) * 2016-11-04 2020-09-16 富士アミドケミカル株式会社 ４−フルオロイソキノリンの製法
CN108627579B (zh) * 2017-03-24 2020-12-01 上海安谱实验科技股份有限公司 Pbt制品中多环芳烃的提取方法
WO2019133605A1 (en) * 2017-12-26 2019-07-04 Astellas Pharma Inc. Process for the preparation of an amino-pyrimidine and intermediates thereof
AU2019375983A1 (en) 2018-11-09 2021-06-10 Vivace Therapeutics, Inc. Bicyclic compounds
HUE070525T2 (hu) 2019-04-16 2025-06-28 Vivace Therapeutics Inc Biciklusos vegyületek
CN111848423B (zh) * 2019-04-30 2022-10-14 尚科生物医药（上海）有限公司 3-氧代环丁基氨基甲酸叔丁酯的制备方法
WO2021257863A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Pyrrolotriazine compounds as jak2 v617f inhibitors
US11691971B2 (en) 2020-06-19 2023-07-04 Incyte Corporation Naphthyridinone compounds as JAK2 V617F inhibitors
US11767323B2 (en) 2020-07-02 2023-09-26 Incyte Corporation Tricyclic pyridone compounds as JAK2 V617F inhibitors
IL299612A (en) 2020-07-02 2023-03-01 Incyte Corp Tricyclic urea compounds as JAK2 V617F inhibitors
US11661422B2 (en) 2020-08-27 2023-05-30 Incyte Corporation Tricyclic urea compounds as JAK2 V617F inhibitors
WO2022140231A1 (en) 2020-12-21 2022-06-30 Incyte Corporation Deazaguaine compounds as jak2 v617f inhibitors
US11958861B2 (en) 2021-02-25 2024-04-16 Incyte Corporation Spirocyclic lactams as JAK2 V617F inhibitors
AU2022380979A1 (en) 2021-11-02 2024-06-06 Flare Therapeutics Inc. Pparg inverse agonists and uses thereof
EP4493558A1 (en) 2022-03-17 2025-01-22 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors

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Also Published As

Publication number Publication date
WO2008139288A3 (en) 2009-03-26
US20110092480A1 (en) 2011-04-21
KR20090130347A (ko) 2009-12-22
EP2155716A2 (en) 2010-02-24
AR066478A1 (es) 2009-08-19
AU2008249745A1 (en) 2008-11-20
US20120065188A1 (en) 2012-03-15
JP2010526130A (ja) 2010-07-29
TW200902518A (en) 2009-01-16
UY31071A1 (es) 2009-01-05
PE20090240A1 (es) 2009-03-19
AU2008249745B2 (en) 2012-01-12
US20080280879A1 (en) 2008-11-13
CN101679357A (zh) 2010-03-24
EP2481735A1 (en) 2012-08-01
PA8779801A1 (es) 2009-01-23
ZA200907761B (en) 2010-08-25
IL201830A0 (en) 2010-06-16
KR20120011093A (ko) 2012-02-06
WO2008139288A2 (en) 2008-11-20
CL2008001367A1 (es) 2008-11-07
CA2685888A1 (en) 2008-11-20

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