UY30606A1 - Derivados 2 y n sustituidos de la 2-metil propionamida, sus tautomeros y sales farmacéuticamente aceptables, composiciones y aplicaciones - Google Patents

Derivados 2 y n sustituidos de la 2-metil propionamida, sus tautomeros y sales farmacéuticamente aceptables, composiciones y aplicaciones

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Publication number
UY30606A1
UY30606A1 UY30606A UY30606A UY30606A1 UY 30606 A1 UY30606 A1 UY 30606A1 UY 30606 A UY30606 A UY 30606A UY 30606 A UY30606 A UY 30606A UY 30606 A1 UY30606 A1 UY 30606A1
Authority
UY
Uruguay
Prior art keywords
tautomeros
substitutes
derivatives
compositions
applications
Prior art date
Application number
UY30606A
Other languages
English (en)
Inventor
James Edward Jenkins
Nigel Blumire
Christopher Francis Palmer
Chandana Chowdhury
Malcolm Taylor
Innocent Mushi
Monika Ermann
David S Thomson
Eugene Richard Hickey
Pier Francesco Cirillo
Angela Berry
Doris Riether
Renee Zindell
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38893310&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY30606(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of UY30606A1 publication Critical patent/UY30606A1/es

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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C07D261/16—Benzene-sulfonamido isoxazoles
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
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    • C07D277/62—Benzothiazoles
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    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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  • Chemical & Material Sciences (AREA)
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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurology (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Abstract

Compuestos de formula (I) se describen. Compuestos segun la invencion se enlazan a y son agonistas, antagonistas o agonistas inversos del receptor CB2, y son utiles para tratar la inflamacion. Los compuestos que son agonistas, son adicionalmente utiles para tratar el dolor.
UY30606A 2006-09-25 2007-09-24 Derivados 2 y n sustituidos de la 2-metil propionamida, sus tautomeros y sales farmacéuticamente aceptables, composiciones y aplicaciones UY30606A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82681906P 2006-09-25 2006-09-25

Publications (1)

Publication Number Publication Date
UY30606A1 true UY30606A1 (es) 2008-05-02

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UY30606A UY30606A1 (es) 2006-09-25 2007-09-24 Derivados 2 y n sustituidos de la 2-metil propionamida, sus tautomeros y sales farmacéuticamente aceptables, composiciones y aplicaciones

Country Status (20)

Country Link
US (2) US7928123B2 (es)
EP (1) EP2074084B1 (es)
JP (1) JP5030114B2 (es)
KR (1) KR20090069318A (es)
CN (1) CN101516839A (es)
AR (1) AR062937A1 (es)
AU (1) AU2007300295A1 (es)
BR (1) BRPI0718515A2 (es)
CA (1) CA2664310A1 (es)
CL (1) CL2007002750A1 (es)
CO (1) CO6160291A2 (es)
EA (1) EA200900403A1 (es)
IL (1) IL197746A0 (es)
MX (1) MX2009002888A (es)
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