EA200900403A1 - Соединения, которые модулируют рецептор св2 - Google Patents

Соединения, которые модулируют рецептор св2

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Publication number
EA200900403A1
EA200900403A1 EA200900403A EA200900403A EA200900403A1 EA 200900403 A1 EA200900403 A1 EA 200900403A1 EA 200900403 A EA200900403 A EA 200900403A EA 200900403 A EA200900403 A EA 200900403A EA 200900403 A1 EA200900403 A1 EA 200900403A1
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EA
Eurasian Patent Office
Prior art keywords
compounds
receptor
modulate
agonists
useful
Prior art date
Application number
EA200900403A
Other languages
English (en)
Inventor
Анджела Берри
Пьер Франческо Чирилло
Юджин Ричард Хикки
Дорис Ритер
Дейвид Томсон
Рене М. Цинделль
Моника Эрманн
Джеймс Эдуард Дженкинс
Инносент Муши
Малколм Тейлор
Чандана Чоудхури
Кристофер Франсис Палмер
Найджел Блумйр
Original Assignee
Бёрингер Ингельхайм Интернациональ Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38893310&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200900403(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Бёрингер Ингельхайм Интернациональ Гмбх filed Critical Бёрингер Ингельхайм Интернациональ Гмбх
Publication of EA200900403A1 publication Critical patent/EA200900403A1/ru

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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D261/16—Benzene-sulfonamido isoxazoles
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Abstract

В заявке описаны соединения формулы (I). Соединения, предлагаемые в настоящем изобретении, связываются с рецептором СВ2 и являются агонистами, антагонистами или обратными агонистами рецептора СВ2 и применимы для лечения воспаления. Те соединения, которые являются агонистами, также дополнительно применимы для устранения боли.
EA200900403A 2006-09-25 2007-09-13 Соединения, которые модулируют рецептор св2 EA200900403A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82681906P 2006-09-25 2006-09-25
PCT/US2007/078341 WO2008039645A1 (en) 2006-09-25 2007-09-13 Compounds which modulate the cb2 receptor

Publications (1)

Publication Number Publication Date
EA200900403A1 true EA200900403A1 (ru) 2009-10-30

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ID=38893310

Family Applications (1)

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EA200900403A EA200900403A1 (ru) 2006-09-25 2007-09-13 Соединения, которые модулируют рецептор св2

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US (2) US7928123B2 (ru)
EP (1) EP2074084B1 (ru)
JP (1) JP5030114B2 (ru)
KR (1) KR20090069318A (ru)
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BRPI0718515A2 (pt) 2013-11-19
MX2009002888A (es) 2009-03-31
US20110130431A1 (en) 2011-06-02
UY30606A1 (es) 2008-05-02
KR20090069318A (ko) 2009-06-30
IL197746A0 (en) 2009-12-24
CL2007002750A1 (es) 2008-05-16
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CA2664310A1 (en) 2008-04-03
PE20080830A1 (es) 2008-07-10
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US20080081822A1 (en) 2008-04-03
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