DE69119434T2 - Anilidderivat - Google Patents
AnilidderivatInfo
- Publication number
- DE69119434T2 DE69119434T2 DE69119434T DE69119434T DE69119434T2 DE 69119434 T2 DE69119434 T2 DE 69119434T2 DE 69119434 T DE69119434 T DE 69119434T DE 69119434 T DE69119434 T DE 69119434T DE 69119434 T2 DE69119434 T2 DE 69119434T2
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- alkoxy
- anilide derivative
- anilide
- alkanoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000003931 anilides Chemical class 0.000 title abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP32213690 | 1990-11-26 | ||
PCT/JP1991/001602 WO1992009572A1 (fr) | 1990-11-26 | 1991-11-21 | Derive d'anilide |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69119434D1 DE69119434D1 (de) | 1996-06-13 |
DE69119434T2 true DE69119434T2 (de) | 1996-09-12 |
Family
ID=18140332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69119434T Expired - Fee Related DE69119434T2 (de) | 1990-11-26 | 1991-11-21 | Anilidderivat |
Country Status (11)
Country | Link |
---|---|
US (1) | US5475130A (de) |
EP (1) | EP0559898B1 (de) |
JP (1) | JP2650096B2 (de) |
KR (1) | KR0169501B1 (de) |
AT (1) | ATE137744T1 (de) |
CA (1) | CA2096970C (de) |
DE (1) | DE69119434T2 (de) |
DK (1) | DK0559898T3 (de) |
ES (1) | ES2088574T3 (de) |
GR (1) | GR3020257T3 (de) |
WO (1) | WO1992009572A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5668136A (en) * | 1990-09-25 | 1997-09-16 | Eisai Co., Ltd. | Trisubstituted benzene derivatives, composition and methods of treatment |
EP0609457B1 (de) * | 1992-07-20 | 1997-10-29 | Eisai Co., Ltd. | Benzolderivate |
WO1995014463A1 (fr) * | 1993-11-25 | 1995-06-01 | Taisho Pharmaceutical Co., Ltd. | Composition de preparation pharmaceutique a absorption perorale amelioree |
FR2729665B1 (fr) * | 1995-01-19 | 1997-04-18 | Pf Medicament | Nouveaux derives de glycylanilides, leur preparation et leur application en therapeutique |
FR2741619B1 (fr) * | 1995-11-28 | 1998-02-13 | Pf Medicament | Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique |
AU721632B2 (en) * | 1997-04-01 | 2000-07-13 | Taisho Pharmaceutical Co., Ltd. | Agent for preventing restenosis |
CN1252715A (zh) * | 1997-04-01 | 2000-05-10 | 大正制药株式会社 | 用于预防局部缺血心脏病的制剂 |
CN1589154A (zh) * | 2001-08-28 | 2005-03-02 | 三共株式会社 | 含有血管紧张肽ii受体拮抗剂的药用组合物 |
US20050119314A1 (en) * | 2002-04-05 | 2005-06-02 | Sankyo Company, Limited | Pharmaceutical composition comprising an ACAT inhibitor and an insulin resistance reducing agent |
EP1689383B1 (de) | 2003-11-19 | 2012-10-31 | Metabasis Therapeutics, Inc. | Neue phosphor enthaltende thyromimetika |
US7923573B2 (en) * | 2004-10-27 | 2011-04-12 | Daiichi Sankyo Company, Limited | Benzene compound having 2 or more substituents |
WO2008014199A2 (en) * | 2006-07-28 | 2008-01-31 | Boehringer Ingelheim International Gmbh | Sulfonyl compounds which modulate the cb2 receptor |
CA2664310A1 (en) * | 2006-09-25 | 2008-04-03 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
JP5492092B2 (ja) * | 2007-11-07 | 2014-05-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を調節する化合物 |
EP2326629B1 (de) * | 2008-07-10 | 2013-10-02 | Boehringer Ingelheim International GmbH | Den cb2-rezeptor modulierende sulfonverbindungen |
RU2011116111A (ru) * | 2008-09-25 | 2012-10-27 | Бёрингер Ингельхайм Интернациональ Гмбх (De) | Сульфонилсодержащие соединения, которые селективно модулируют рецептор св2 |
WO2010093601A1 (en) | 2009-02-10 | 2010-08-19 | Metabasis Therapeutics, Inc. | Novel sulfonic acid-containing thyromimetics, and methods for their use |
US8299103B2 (en) | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
WO2010147791A1 (en) | 2009-06-16 | 2010-12-23 | Boehringer Ingelheim International Gmbh | Azetidine 2 -carboxamide derivatives which modulate the cb2 receptor |
WO2011037795A1 (en) * | 2009-09-22 | 2011-03-31 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the cb2 receptor |
JP2013517271A (ja) | 2010-01-15 | 2013-05-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を調節する化合物 |
EP2542539B1 (de) | 2010-03-05 | 2014-02-26 | Boehringer Ingelheim International GmbH | Tetrazolverbindungen für selektive cb2-rezeptormodulation |
US8846936B2 (en) | 2010-07-22 | 2014-09-30 | Boehringer Ingelheim International Gmbh | Sulfonyl compounds which modulate the CB2 receptor |
EP2803668A1 (de) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Neuartige (Cyano-dimethyl-methyl)-isoxazole und -[1,3,4]-thiadiazole |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3878248A (en) * | 1971-05-03 | 1975-04-15 | Monsanto Co | Substituted alpha, alpha-dichloro-methane-sulfenyl chlorides |
JPS5439028A (en) * | 1977-08-31 | 1979-03-24 | Hokko Chem Ind Co Ltd | Acetanilide derivatives and bactericides containing the same for agricultural and horticultural, uses |
US4329363A (en) * | 1978-09-08 | 1982-05-11 | Merck & Co., Inc. | Substituted mercapto acid amides and their use |
US4623662A (en) * | 1985-05-23 | 1986-11-18 | American Cyanamid Company | Antiatherosclerotic ureas and thioureas |
FR2540495B1 (fr) * | 1983-02-07 | 1986-02-14 | Roussel Uclaf | Nouveaux derives de o-mercaptopropanamide et de ses homologues, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus |
GB2149394B (en) * | 1983-07-19 | 1986-09-24 | American Cyanamid Co | Ureas |
US4859707A (en) * | 1983-08-23 | 1989-08-22 | Key Pharmaceuticals, Inc. | Sulfur-substituted phenylacetamides |
AU584669B2 (en) * | 1985-02-04 | 1989-06-01 | G.D. Searle & Co. | Novel disubstituted 4-hydroxyphenylthio anilides |
ZA871597B (en) * | 1986-03-24 | 1988-10-26 | Warner Lambert Co | Substituted anilides of oleic,linoleic,or linolenic acid as inhibitors of acyl-coa:cholestrol acyltransferase |
US4716175A (en) * | 1987-02-24 | 1987-12-29 | Warner-Lambert Company | Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase |
EP0361365A1 (de) * | 1988-09-30 | 1990-04-04 | E.R. SQUIBB & SONS, INC. | Derivate von Aminobenzoesäure und Aminocyclohexancarbonsäure, Zusammensetzungen und ihre Verwendung |
MX22406A (es) * | 1989-09-15 | 1994-01-31 | Pfizer | Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat). |
-
1991
- 1991-11-21 KR KR1019930701531A patent/KR0169501B1/ko not_active IP Right Cessation
- 1991-11-21 DK DK92902521.1T patent/DK0559898T3/da active
- 1991-11-21 EP EP92902521A patent/EP0559898B1/de not_active Expired - Lifetime
- 1991-11-21 US US08/064,073 patent/US5475130A/en not_active Expired - Fee Related
- 1991-11-21 CA CA002096970A patent/CA2096970C/en not_active Expired - Fee Related
- 1991-11-21 JP JP4500533A patent/JP2650096B2/ja not_active Expired - Lifetime
- 1991-11-21 DE DE69119434T patent/DE69119434T2/de not_active Expired - Fee Related
- 1991-11-21 WO PCT/JP1991/001602 patent/WO1992009572A1/ja active IP Right Grant
- 1991-11-21 ES ES92902521T patent/ES2088574T3/es not_active Expired - Lifetime
- 1991-11-21 AT AT92902521T patent/ATE137744T1/de not_active IP Right Cessation
-
1996
- 1996-06-19 GR GR960401636T patent/GR3020257T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2096970A1 (en) | 1992-05-27 |
ES2088574T3 (es) | 1996-08-16 |
KR0169501B1 (ko) | 1999-03-20 |
DK0559898T3 (da) | 1996-08-19 |
EP0559898A1 (de) | 1993-09-15 |
DE69119434D1 (de) | 1996-06-13 |
EP0559898A4 (de) | 1994-01-12 |
EP0559898B1 (de) | 1996-05-08 |
JP2650096B2 (ja) | 1997-09-03 |
KR930702254A (ko) | 1993-09-08 |
GR3020257T3 (en) | 1996-09-30 |
ATE137744T1 (de) | 1996-05-15 |
WO1992009572A1 (fr) | 1992-06-11 |
US5475130A (en) | 1995-12-12 |
CA2096970C (en) | 1998-07-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |