US20130023851A1 - System and method for administering medicaments to a patient - Google Patents

System and method for administering medicaments to a patient Download PDF

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Publication number
US20130023851A1
US20130023851A1 US13/577,017 US201113577017A US2013023851A1 US 20130023851 A1 US20130023851 A1 US 20130023851A1 US 201113577017 A US201113577017 A US 201113577017A US 2013023851 A1 US2013023851 A1 US 2013023851A1
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United States
Prior art keywords
medicament
data
patient
supply device
identification element
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Abandoned
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US13/577,017
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English (en)
Inventor
Hans-Otto Maier
Torsten Doenhoff
Horst Schmoll
Matthias Paetzold
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B Braun Melsungen AG
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B Braun Melsungen AG
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Assigned to B. BRAUN MELSUNGEN AG reassignment B. BRAUN MELSUNGEN AG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DOENHOFF, TORSTEN, MAIER, HANS-OTTO, SCHMOLL, HORST, PAETZOLD, MATTHIAS
Publication of US20130023851A1 publication Critical patent/US20130023851A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • A61B5/157Devices characterised by integrated means for measuring characteristics of blood
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/08Sensors provided with means for identification, e.g. barcodes or memory chips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • AHUMAN NECESSITIES
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    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229Pumps for assisting the blood sampling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150236Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
    • AHUMAN NECESSITIES
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    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150244Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
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    • A61B5/150381Design of piercing elements
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    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150763Details with identification means
    • A61B5/150786Optical identification systems, e.g. bar codes, colour codes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/155Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4836Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M2005/14208Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6009General characteristics of the apparatus with identification means for matching patient with his treatment, e.g. to improve transfusion security
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/20Blood composition characteristics
    • A61M2230/201Glucose concentration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00871Communications between instruments or with remote terminals
    • G01N2035/00881Communications between instruments or with remote terminals network configurations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection

Definitions

  • the invention relates to a system and a method for administering medicaments to a patient.
  • the supply device can be an insulin supply device or an infusion pump which keeps the insulin value present inside the bloodstream of the patient at a pre-determinable level in reaction to a previously measured blood glucose value in the bloodstream of the patient.
  • supply devices for at least one nutritional value of a food supplied to the bloodstream directly or indirectly by at least one food supply device can be administered to the patient.
  • Supply devices of this type have in common the fact that, even if they are integrated into a system for administering medicaments and/or nutritional values, they require the entering of values which are based upon supply by means of the supply device to be carried out by a doctor or a further clinical member of staff. For example, quantity values, time intervals in which the supply is to be carried out, intermittent supplies etc. can be entered here as a basis for the supply of insulin for example which is to be subsequently carried out.
  • supply devices of this type such as infusion pumps, have a feed rate which is indicated in the form of volume per unit of time (ml/h).
  • the dosage unit is used in medicine for a supplied medicament solution. Consequently it is necessary for the dosage unit to be converted into a feed rate of the pump, which is the task of the attending doctor.
  • a disadvantage of a conversion of this type can be frequent calculation errors, which lead to erroneous entries of the feed rate and thus to an incorrect administration of insulin to the patient.
  • Supply devices or feed apparatus for the supply of a medicament solution mixture into a body are known in a multiplicity of forms.
  • apparatus/systems with a plurality of infusion and/or injection pumps are known, each of which supplies a solution with at least one specific active material of a medicament to a body and, as a result, a medicament solution mixture is formed.
  • Infusion pump systems of this type are frequently used in the case of patients who require an intensive medical treatment.
  • the infusion pumps have the property of continuous precise dosing of the medication in their supply.
  • the pumps are integrated in a common classification system which usually has a central control unit, an operating unit and an alarming unit.
  • a common classification system which usually has a central control unit, an operating unit and an alarming unit.
  • the object of the invention is to make available a system and a method for administering medicaments to a large number of patients which makes available a high degree of reliability in the allocation of the correct medicament to the respective patient and his or her supply device.
  • the key concept of the invention is that in a system for administering medicaments to a large number of patients, in particular to a selected patient, the following features are present:
  • At least one mobile medicament container with at least one liquid medicament at least one mobile medicament container with at least one liquid medicament
  • an identification element production device for producing at least one first identification element with first data relating to the person, medicament and/or treatment in order to attach them to the medicament container;
  • At least one reading device for reading the first data from or out of the first identification element
  • a supply device for supplying the medicament from the medicament container inserted in the supply device to the patient;
  • the reading device likewise being suitable for reading second data, which are attached to or in a second identification element which is allocated to the patient, and being connected to the supply device, and
  • control unit inside the supply device transmitting a first control signal for activating the supply procedure to one of a plurality of supply units of the supply device if the first and the second data correspond at least in part.
  • a system of this type is advantageously characterized in that it provides a high degree of reliability in the transfer of a prepared medicament in a medicament container provided therefore to a respective supply device of a patient with respect to the correct allocation, since on account of using identification elements with the data attached to or in them a confusion of medicament containers of this type with the medicaments contained in them is no longer possible. On account of reading and comparing different data, confusion of the medicaments is in fact eliminated.
  • a first comparator unit inside the supply device for comparing the first and second data with respect to the correspondence of the data relating to the person.
  • the person or the patient according to the first data who has already served in the preparation of the medicament as the allocated person for the medicament produced, can be compared with those data—relating to the person—of the second data which can be taken from an armband or the like which is attached to the person.
  • the supply device which can be an insulin pump, is not capable of being activated.
  • the insulin pump for example is in fact capable of being activated only when it receives the correct medicament with the associated medicament container, such as for example a syringe, and establishes a correspondence of the data relating to the person which are present on the syringe and on the patient.
  • the associated medicament container such as for example a syringe
  • a second comparator unit inside the supply device is provided for comparing the data—relating to the medicament—of the first data with the second data relating to the medicament contained in a memory unit of the supply device.
  • the second comparator unit of the supply device permits a supply procedure only when the first data—relating to the medicament—of the first data which are attached to the identification element of the medicament container are within a parameter or data range which has been saved inside the memory unit as being permissible and suitable for the second data relating to the medicament.
  • each composition of the previously prepared medicament can be conveyed automatically through the identification element production device to the identification element, so as to ensure that no constituents or portions of the composition are overlooked by the attending person.
  • a selection unit of the supply device is provided for the selection at least in part of the first and/or the second data relating to the medicament.
  • This selection unit is intended to be used so that the correct data relating to the medicament is selected.
  • first data relating to the medicament which are arranged on the medicament container by means of the identification element, or to the second data relating to the medicament which are saved inside the memory unit of the supply device, in order optionally to select this more advantageous medicament composition.
  • parameters of the selected second data relating to the medicament or of the selected first data relating to the medicament can be changed in order to be able to administer an altered medicament composition with other dosages on the basis of events which have occurred only recently.
  • a blocking unit for blocking the start of a supply procedure on receipt of a second control signal of the control unit, the control unit sending this second control signal when the first and second data do not correspond at least in part.
  • a blocking unit of this type has the aim that the continuation of the procedure which is intended to start a supply procedure of a medicament to the patient is not possible from the supply device, if non-corresponding data are established. This means that a stoppage of the procedure by the appliance automatically occurs if non-corresponding data are established.
  • a high degree of reliability should be provided for a correct allocation of the medicament to the respective patient.
  • the risk of a wrong allocation of a medicament to the wrong patient is eliminated by this, since the infusion pump or the supply device simply does not permit such an administration of a medicament.
  • the identification element is advantageously a barcode label, a Data Matrix code label and/or a transponder.
  • These labels can advantageously be secured by adhesion to the outer face of the medicament container, in which case the barcode label and the Data Matrix code label are printed out of the identification element production device and where a transponder is present the data are saved on the transponder by means of a writer.
  • This transponder can then be read out on the supply device by means of a reader, whereas the barcode label and the Data Matrix code label can be read out by means of a barcode scanner or a Data Matrix code scanner.
  • the supply device prefferably be an insulin pump
  • the supply unit to be one of a plurality of insulin pump units
  • the medicament container to be a syringe.
  • a method of this type allows the self-acting or automatic comparison of read data in order to ensure that only when there is a correspondence of the read data is the procedure continued and so a supply procedure of the medicament to the patient is possible. This results in a high degree of reliable allocation of the correct medicament to the correct patient in order to prevent the administration of wrong medicaments and thus further undesired symptoms of the patient.
  • the method according to the invention in a step of reading third data which are attached to or in a third identification element which is allocated to a person treating the patient that only the authorized attending person, i.e. a person from the clinical staff, will perform the administration of the medicament with the correct allocation to the patient. Other persons thus have no access to the administration appliance which constitutes the supply device. As a result, a protection against unauthorized actuation of the supply device and the supply of medicaments can be achieved.
  • first data—relating to the medicament—of the first data with second data relating to the medicament saved in a memory unit of the supply device.
  • this step it is ensured that first data relating to the medicament which are saved on the identification element are compared with second data relating to the medicament saved in the memory unit, and in this way it can be established whether the medicament composition inside the medicament container corresponds to a permitted medicament composition range within which the medicaments to be administered are to lie.
  • FIG. 1 is a diagrammatic illustration of the system according to the invention in accordance with an embodiment of the invention in its functional sequence
  • FIGS. 2 a and 2 b show the method according to the invention in accordance with an embodiment of the invention.
  • FIG. 1 is a diagrammatic illustration of the system—according to the invention—of an embodiment of the invention.
  • the medicament composition with the respective data relating to the person and the manner of treatment is entered in a computer device 1 by the medical staff by means of a keyboard 2 .
  • a barcode 5 a which contains at least parts of the first data relating to the person, the medicament and/or the treatment is printed inside an identification element production device 3 which is present in the form of a barcode printer.
  • This barcode is printed out in the form of a label and comprises for example a patient identification number as data relating to the person, the name of the medicament and the concentration thereof as data relating to the medicament, and different dosage parameters, such as for example the duration of the dosage, as data relating to the treatment.
  • the barcode label can have the inscription “Hans Müller”, “Adrenalin”, “2 mg/50” in addition to the barcode or the Data Matrix code.
  • the medicament is prepared in a composition in a medicament preparation station 4 and is supplied to the syringe 5 .
  • the barcode 5 a is secured by adhesion to the syringe 5 by means of an adhesive surface.
  • the barcode label 5 a is read out in a reading device 6 by means of a barcode scanner 7 , as a result of which the data relating to the person, the medicament and/or the treatment are read in inside a supply device 11 .
  • a barcode which is provided on an armband 10 of a patient 9 and likewise contains data relating to the person, is read out from this armband 10 by means of a further or the same barcode scanner 8 .
  • the data provided are then passed on to a first comparator unit 15 which is preferably arranged inside the supply device 11 .
  • the comparator unit 15 compares the data relating to the person, as provided on the armband 10 by means of a barcode for example, with the data relating to the person on the barcode label 5 a, as originally produced by the computer unit 1 with reference to the medicament produced by the medicament preparation station 4 .
  • first comparator unit 15 If correspondence of the data relating to the person, but also optionally of the data relating to the medicament, is established inside the first comparator unit 15 , an appropriate signal is passed on from the first comparator unit 15 to a control unit 16 which causes a first control signal 13 to be sent by means of a control line to the infusion syringe 14 used, in order to actuate the supply unit 12 b for compressing the syringe 14 .
  • syringes which contain different medicaments for administration to the patient, can be arranged in different supply units 12 a, 12 b, 12 c, 12 d and 12 e.
  • the syringe 14 is that syringe 5 which contains the medicament as has been prepared beforehand.
  • the control unit 16 will send an appropriate signal to a blocking unit 20 in order to effect a termination of the procedure and a blocking of the entire supply device 11 by means of this blocking unit. This ensures that the person is not allocated the wrong medicament, since the medicament contains data relating to the person and the armband of the person 19 or of the patient 19 respectively contains data relating to the person which have to correspond thereto.
  • third data which contain the person-related data of a nurse are read in by means of the barcode scanner 7 or the barcode scanner 8 from an armband of the nurse. These third data are used to compare the latter with permanently saved data which can be contained for example in a memory unit 19 , in order to establish that the nurse has authorized access for operating the appliance or this supply device 11 . If it is established that other person-related data are involved here, for example since this nurse is not authorized to administer insulin, then—in accordance with the signals of a control unit—the ⁇ blocking unit 20> is in turn activated and causes a conclusion of the procedure of the supply device 11 .
  • Data—relating to the medicament—of the first data are compared with second data relating to the medicament which are contained in the memory unit 19 .
  • This comparison is carried out inside a second comparator unit 18 . If it is established in a comparison of this type that there are deviations between the first data relating to the medicament read in by means of the barcode scanner 7 and the second data relating to the medicament from the memory unit 19 , or the first data are outside a range provided for the second data, then the user or the nurse is asked by means of a display unit and input unit 17 whether he or she still wants to continue the treatment and which data he or she wants to implement. As a result, the nurse can select the first data relating to the medicament or the second data relating to the medicament in order to continue the treatment.
  • the nurse can of course make a change to the parameters on the supply device 11 by means of the display and input unit 17 , in order for example to change as a result the dosage of the medicament to be administered. This takes place in the constant data exchange with the control unit 16 which subsequently in turn actuates the supply unit 12 b accordingly.
  • an appropriate fault signal is sent by means of a selection unit 21 to the control unit 16 which in turn actuates the supply unit 12 b with the syringe 14 inserted therein in accordance with the selected data in order to start the supply procedure or, where appropriate, to continue it.
  • an automated documentation of the administration parameters and the entire supply procedure as well as the entire sequence is in turn produced automatically, this preferably being carried out in the computer unit 1 .
  • This can be carried out by means of wireless LAN for example as indicated by the arrow 22 .
  • FIGS. 2 a and 2 b The method according to the invention is shown in accordance with an embodiment of the invention in FIGS. 2 a and 2 b.
  • a step 25 the preparation of a medicament in accordance with the parameters and data entered is carried out.
  • a step 26 an automated formation of a barcode label for application to a medicament container is then carried out.
  • step 27 the attachment of the barcode label as an ID element is then carried out by means of an adhesive surface for example.
  • a comparison is now carried out between the first and the second data for the correspondence thereof in accordance with step 30 , in order to effect a conclusion of the entire procedure in the event of non-correspondence in accordance with step 31 . If corresponding data, in particular with respect to data relating to the person, are established, however, a reading 32 of third data takes place, which in a step 33 are in turn compared with data already saved in the insulin pump. These are data on the attending person in order to establish whether this person is authorized for access. If this is negative, in a step 34 no permission for treatment is allowed and termination takes place.
  • step 35 first data relating to the medicament are compared for correspondence with second data relating to the medicament. This is intended to ensure that the data of the barcode relating to the medicament, as indicated on the syringe, do not differ in an undesired manner from data ranges relating to the medicament as provided which have already been saved inside the insulin pump. If a comparison of this type leads to a denial with respect to the correspondence, in a step 36 a conclusion of the procedure is carried out.
  • a release signal is sent in a step 37 to one of the supply units and an activation of the supply procedure takes place. After that, a display of supply parameters is carried out in a step 38 .
  • step 39 With renewed preparation in the event of a change in measured blood glucose reference values in accordance with step 39 the cycle is started from the beginning as shown by arrow 40 .

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US13/577,017 2010-03-05 2011-03-03 System and method for administering medicaments to a patient Abandoned US20130023851A1 (en)

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DE102010010567 2010-03-05
DE102010010567.8 2010-03-05
DE102010012733.7 2010-03-24
DE102010012733 2010-03-24
PCT/EP2011/053246 WO2011107569A1 (de) 2010-03-05 2011-03-03 System und verfahren zur verabreichung von medikamenten für einen patienten

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US13/521,713 Abandoned US20130023819A1 (en) 2010-03-05 2011-03-03 System and method for monitoring at least one blood parameter
US13/581,225 Abandoned US20120323141A1 (en) 2010-03-05 2011-03-03 System for determining treatment-related data for the administration of drugs to patients to be treated taking into account important individual factors
US13/577,017 Abandoned US20130023851A1 (en) 2010-03-05 2011-03-03 System and method for administering medicaments to a patient
US13/579,858 Active 2033-11-09 US9861745B2 (en) 2010-03-05 2011-03-03 System and method for monitoring time intervals during blood parameter monitoring
US13/578,799 Abandoned US20120323215A1 (en) 2010-03-05 2011-03-03 System and method for administering medicaments on the basis of urine values
US13/575,857 Abandoned US20120316465A1 (en) 2010-03-05 2011-03-03 System and method for monitoring the time period for blood parameter monitoring processes

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US13/575,857 Abandoned US20120316465A1 (en) 2010-03-05 2011-03-03 System and method for monitoring the time period for blood parameter monitoring processes

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ES2904601T3 (es) 2022-04-05
RU2524121C2 (ru) 2014-07-27
AU2011222944A1 (en) 2012-08-30
US20130085471A1 (en) 2013-04-04
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US9861745B2 (en) 2018-01-09
IL221166B (en) 2018-06-28
CA2788603C (en) 2017-05-23
CN102713615A (zh) 2012-10-03
JP5758409B2 (ja) 2015-08-05
CA2789191C (en) 2017-10-31
CA2788057A1 (en) 2011-09-09
US20120316465A1 (en) 2012-12-13
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JP2013519481A (ja) 2013-05-30
RU2012127707A (ru) 2014-01-20
SG183254A1 (en) 2012-09-27
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JP5485414B2 (ja) 2014-05-07
JP2013520718A (ja) 2013-06-06
BR112012020923A2 (pt) 2020-01-14
BR112012019133A2 (pt) 2018-03-27
AU2011222942A1 (en) 2012-08-30
CA2789191A1 (en) 2011-09-09
AU2011222942B2 (en) 2014-05-08
RU2543941C2 (ru) 2015-03-10
WO2011107568A1 (de) 2011-09-09
RU2012134289A (ru) 2014-02-27
RU2012133280A (ru) 2014-02-10
JP5592506B2 (ja) 2014-09-17
IL221373A0 (en) 2012-10-31
SG183353A1 (en) 2012-09-27
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AU2011222947B2 (en) 2014-09-18
MX2012009598A (es) 2012-09-12

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