US20120018318A1 - Two-drug pharmaceutical container - Google Patents

Two-drug pharmaceutical container Download PDF

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Publication number
US20120018318A1
US20120018318A1 US13/260,579 US201013260579A US2012018318A1 US 20120018318 A1 US20120018318 A1 US 20120018318A1 US 201013260579 A US201013260579 A US 201013260579A US 2012018318 A1 US2012018318 A1 US 2012018318A1
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US
United States
Prior art keywords
main body
nozzle cap
container main
cap
ratchet teeth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US13/260,579
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English (en)
Inventor
Tadashi Otsuka
Takashi Fujimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Hanshin Kasei Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd, Hanshin Kasei Kogyo Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Assigned to SENJU PHARMACEUTICAL CO., LTD. reassignment SENJU PHARMACEUTICAL CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: FUJIMOTO, TAKASHI, OTSUKA, TADASHI
Assigned to SENJU PHARMACEUTICAL CO., LTD., HANSHIN KASEI CO., LTD. reassignment SENJU PHARMACEUTICAL CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: FUJIMOTO, TAKASHI, OTSUKA, TADASHI
Publication of US20120018318A1 publication Critical patent/US20120018318A1/en
Assigned to SENJU PHARMACEUTICAL CO., LTD. reassignment SENJU PHARMACEUTICAL CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HANSHIN KASEI CO., LTD.
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D41/00—Caps, e.g. crown caps or crown seals, i.e. members having parts arranged for engagement with the external periphery of a neck or wall defining a pouring opening or discharge aperture; Protective cap-like covers for closure members, e.g. decorative covers of metal foil or paper
    • B65D41/32—Caps or cap-like covers with lines of weakness, tearing-strips, tags, or like opening or removal devices, e.g. to facilitate formation of pouring openings
    • B65D41/34—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D41/00—Caps, e.g. crown caps or crown seals, i.e. members having parts arranged for engagement with the external periphery of a neck or wall defining a pouring opening or discharge aperture; Protective cap-like covers for closure members, e.g. decorative covers of metal foil or paper
    • B65D41/32—Caps or cap-like covers with lines of weakness, tearing-strips, tags, or like opening or removal devices, e.g. to facilitate formation of pouring openings
    • B65D41/34—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt
    • B65D41/3404—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt with ratchet-and-pawl mechanism between the container and the closure skirt or the tamper element
    • B65D41/3409—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt with ratchet-and-pawl mechanism between the container and the closure skirt or the tamper element the tamper element being integrally connected to the closure by means of bridges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A61J1/1418—Threaded type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D35/00—Pliable tubular containers adapted to be permanently or temporarily deformed to expel contents, e.g. collapsible tubes for toothpaste or other plastic or semi-liquid material; Holders therefor
    • B65D35/44—Closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/18—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein

Definitions

  • the present invention relates to a two-drug pharmaceutical container whose container main body containing a first ingredient is opened to add a second ingredient thereinto, and the container main body is thereafter again closed to be used for the purpose of eye drops or the like.
  • the present invention relates to a two-drug pharmaceutical container in which a ratchet mechanism is provided at its nozzle cap and container main body in order to prevent inadvertent opening by a user, to prevent the nozzle cap from being loosened in the opening direction.
  • a two-drug pharmaceutical container whose container main body containing a first ingredient is opened to add a second ingredient thereinto, and the container main body is thereafter again closed to be used for the purpose of eye drops or the like
  • a two-drug pharmaceutical container in which a nozzle cap is screwed onto a container main body, a medicinal solution extracting orifice is provided at a head section of the nozzle cap, and a cap is screwed onto the head section, is known.
  • Patent Document 1 Japanese Published Unexamined Patent Application-Hei-7-257610
  • the nozzle cap is rotated in the opening direction to remove the nozzle cap from the container main body to add a second ingredient into the case main body, and the nozzle cap is rotated in the closing direction to close the container main body, and thereafter, when the cap is rotated in the opening direction to remove the cap from the nozzle cap to administer eye drops or the like, the nozzle cap as well may be rotated in the opening direction at the same time in some cases, and the medicinal solution may spill out from the mouth portion of the loose container main body in some cases.
  • a container including a ratchet mechanism in order not to allow its container main body and cap to be opened is known.
  • a container which is configured so that ratchet teeth are respectively provided on the outer side of the terminal end of its cervical part of the container and on the inner side of the cap (Patent Document 1).
  • Patent Document 1 is applicable as is to a single-drug pharmaceutical container, but is not applicable as is to a two-drug pharmaceutical container associated with an operation of removing the nozzle cap in order to add a second ingredient into the container main body containing a first ingredient.
  • the present invention has been achieved in consideration of the above-described circumstances. It is a primary object of the present invention to provide a two-drug pharmaceutical container in which a nozzle cap is screwed onto a container main body, a medicinal solution extracting orifice is provided at a head section of the nozzle cap, and a cap is screwed onto the head section, in the two-drug pharmaceutical container, the container main body and the nozzle cap are not loosened in any case until mixture of two medicinal solutions, these can be easily removed by breaking a ratchet section at the time of mixture, and further, when these are again closed after mixture, this portion is not easily opened thereafter, therefore, even when the cap is turned in the opening direction, the nozzle cap and the container main body are not loosened in any case, that keeps the closed state, which makes it possible to remove only the cap.
  • a two-drug pharmaceutical container including
  • a container main body which is filled with a first ingredient, and provided with a male screw on an outer circumferential surface of a nozzle section,
  • a nozzle cap which has a body section provided with a female screw screwed together with the male screw on an inner circumferential surface of its tube body, a head section including a medicinal solution extracting orifice communicated with an inside of the body section, and a sealing ring part provided via a plurality of breakable joining sections which are provided along a circumferential direction on a lower edge of the body section, and
  • a small diameter annular section with an outer diameter larger than an outer diameter of the male screw of the nozzle section and a large diameter annular section, which is on the lower side of the small diameter annular section, with an outer diameter larger than the outer diameter of the small diameter annular section are provided at a lower portion of the nozzle section of the container main body, and upper stage external ratchet teeth and lower stage external ratchet teeth are respectively provided on an outer circumferential surface of the small diameter annular section and an outer circumferential surface of the large diameter annular section, and on the other hand, upper stage internal ratchet teeth and lower stage internal ratchet teeth are respectively provided on an inner circumferential surface of a lower portion of the body section and an inner circumferential surface of the sealing ring part in the components of the nozzle cap,
  • a downward protruding piece is provided on the lower edge of the body section and an upward protruding piece is provided so as to come close to the closing side in the circumferential direction from the downward protruding piece on an upper edge of the sealing ring part in the components of the nozzle cap, and the front part lower end of the downward protruding piece is extended downward from the rear part upper end of the upward protruding piece.
  • the two-drug pharmaceutical container according to [1] or [2], the container is used for any purpose of eye drops, ear drops, and nose drops.
  • a method for using the two-drug pharmaceutical container including the successive processes of
  • the container main body and the nozzle cap are not easily loosened in any case. Then, when the nozzle cap is operated to turn in the opening direction at the time of adding a second ingredient, the joining sections are broken while the lower stage internal ratchet teeth and the lower stage external ratchet teeth engage with each other to prevent turning in the opening direction, which makes it possible to remove the nozzle cap.
  • the two-drug pharmaceutical container is configured so that a sealing ring part is removed from the container main body to add a second ingredient into the container main body containing a first ingredient, and thereafter, when the nozzle cap without a sealing ring part because of the breakage of the joining sections is operated to turn in the closing direction to close the container main body, and next the cap is operated to turn in the opening direction, the upper stage internal ratchet teeth and the upper stage external ratchet teeth engage with each other to prevent turning in the opening direction, the closed state between the nozzle cap and the container main body is kept, which makes it possible to remove only the cap.
  • FIG. 1 is an exploded perspective view of a two-drug pharmaceutical container according to the present invention whose cap is not shown and whose nozzle cap is partially cut out.
  • FIG. 2A is a view of the container main body in FIG. 1 viewed from above.
  • FIG. 2B is a view of the container main body in FIG. 1 viewed from the front.
  • FIG. 3A is a front half sectional view of the nozzle cap in FIG. 1 .
  • FIG. 3B is a view of the nozzle cap of FIG. 3A viewed from below.
  • FIG. 4 is a side view of the nozzle cap in FIG. 1 .
  • FIG. 5A is a longitudinal sectional view showing the state of the container of FIG. 1 before use.
  • FIG. 5B is a longitudinal sectional view of FIG. 5A taken along line A-A.
  • FIG. 6A is a longitudinal sectional view showing the state in which the container main body is closed with the nozzle cap from which a sealing ring part is removed by breaking joining sections.
  • FIG. 6B is a cross sectional view of FIG. 6A taken along line B-B.
  • a two-drug pharmaceutical container is composed of a container main body 1 , a nozzle cap 2 , and a cap 3 which are all made of synthetic resin, and can be suitably used for the purpose of, for example, eye drops, ear drops, nose drops, or the like.
  • a cylindrical body section 11 which is filled with a first ingredient (not shown), and the container main body 1 has a nozzle section 12 which is consecutively installed upward from the body section 11 .
  • a male screw 13 is provided on the outer circumferential surface of the nozzle section 12 , and a small diameter annular section 14 with an outer diameter larger than an outer diameter of the male screw 13 and a large diameter annular section 15 , which is on the lower side of the small diameter annular section 14 , with an outer diameter larger than the outer diameter of the small diameter annular section 14 are consecutively installed to the lower portion of the nozzle section 12 .
  • Upper stage external ratchet teeth 16 and lower stage external ratchet teeth 17 are respectively provided on an outer circumferential surface of the small diameter annular section 14 and an outer circumferential surface of the large diameter annular section 15 .
  • the respective teeth composing the upper stage external ratchet teeth 16 are formed into the same shape that is saw-like, two groups of the teeth 16 in which five teeth are consecutively installed at regular pitches are provided so as to face each other on the outer circumferential surface of the small diameter annular section 14 , and the two teeth 16 are provided so as to face each other at positions respectively shifted by approximately 90 degrees from these groups of the teeth 16 on the outer circumferential surface.
  • the respective teeth composing the lower stage external ratchet teeth 17 are formed into the same shape that is saw-like, and the four teeth 17 are provided at regular pitches on an outer circumferential surface of the large diameter annular section 15 .
  • the nozzle cap 2 forms a cylindrical shape where a head section 21 , a body section 22 , a sealing ring part 23 are integrally molded in its central axis direction.
  • the body section 22 has a shorter internal tube 24 and a longer external tube 25 on the outer side of the internal tube 24 , and an antislip knurl 26 and a female screw 27 screwed together with the male screw 13 of the nozzle section 12 are respectively provided on the outer circumferential surface of the external tube 25 and the inner circumferential surface of the external tube 25 , and upper stage internal ratchet teeth 28 are provided at the lower portion of the inner circumferential surface of the external tube 25 .
  • the respective teeth composing the upper stage internal ratchet teeth 28 are formed into the same shape that is saw-like, and are provided in large numbers so as to go around the inner circumferential surface at regular pitches on the inner circumferential surface of the external tube 25 .
  • the sealing ring part 23 has an outer diameter larger than the outer diameter of the external tube 25 , and lower stage internal ratchet teeth 29 are provided on the inner circumferential surface of the sealing ring part 23 .
  • the sealing ring part 23 is jointed together with breakable joining sections 41 which is provided on the lower edge of the body section 22 along the circumferential direction through its lower edge, to be jointed together with the body section 22 (refer to FIG. 3 ).
  • the respective teeth composing the lower stage internal ratchet teeth 29 are formed into the same shape that is saw-like, and four groups of the teeth 29 in which six teeth are consecutively installed at regular pitches are provided at regular pitches on the inner circumferential surface of the sealing ring part 23 .
  • a downward protruding piece 42 is provided on the lower edge of the body section 22 , and an upward protruding piece 43 is provided so as to come close to the closing side in the circumferential direction from the downward protruding piece 42 (on the left side from the downward protruding piece 42 in FIG. 4 ) on the same circumference on an upper edge of the sealing ring part 23 in the components of the nozzle cap 2 , and the front part lower end of the downward protruding piece 42 is extended downward from the rear part upper end of the upward protruding piece 43 .
  • the head section 21 is provided with a male screw 21 a on its outer circumferential surface, and is provided with a medicinal solution extracting orifice 21 b communicated with an inside of the body section 22 in its apical portion.
  • the cap 3 includes an apical wall 31 and a tube section 33 which is installed vertically downward from the peripheral edge of the apical wall 31 and provided with a male screw 32 screwed together with the male screw 21 a of the head section 21 on its inner circumferential surface.
  • the male screw 13 of the container main body 1 and the female screw 27 of the nozzle cap 2 , and the male screw 21 a of the head section 21 of the nozzle cap 2 and the female screw 32 of the cap 3 are respectively screwed together, as a result, the container main body 1 , the nozzle cap 2 , and the cap 3 are screwed to each other (refer to FIG. 5 ).
  • the container according to the present invention is configured so that, in a closed state in which the female screw 27 of the body section 22 of the nozzle cap 2 is screwed together with the male screw 13 of the container main body 1 to be turned up to a position at which the container main body 1 is closed, although the upper stage internal ratchet teeth 28 and the upper stage external ratchet teeth 16 do not engage with each other, the lower stage internal ratchet teeth 29 and the lower stage external ratchet teeth 17 engage with each other to prevent turning in the opening direction (in the direction of an arrow of FIG. 5B ). Accordingly, the container main body 1 and the nozzle cap 2 are not loosened before use in any case.
  • the container according to the present invention is configured so that, in a closed state in which the sealing ring part 23 is removed from the container main body 1 by breaking the joining sections 41 of the nozzle cap 2 , and the female screw 27 of the body section 22 of the nozzle cap 2 without the sealing ring part 23 is screwed together with the male screw 13 of the container main body 1 to be turned up to the position at which the container main body 1 is closed, the upper stage internal ratchet teeth 28 and the upper stage external ratchet teeth 16 engage with each other to prevent turning in the opening direction (in the direction of an arrow of FIG. 6B ). Accordingly, provided that the cap 3 is turned in the opening direction (in a counterclockwise direction viewed from above) in this state, the closed state between the nozzle cap 2 and the container main body 1 is kept, which makes it possible to remove only the cap 3 .
  • the nozzle cap 2 is operated to turn in the opening direction to remove the nozzle cap 2 from the container main body 1 (first step), next, a second ingredient (not shown) is added into the container main body 1 and the nozzle cap 2 is again operated to turn in the closing direction to close the container main body 1 (second step), and next, the cap 3 is operated to turn in the opening direction to remove the cap 3 from the nozzle cap 2 , to discharge a medicinal solution containing the first ingredient and the second ingredient from the medicinal solution extracting orifice 21 b (third step).
  • the first step when the nozzle cap 2 is operated to turn in the opening direction (in the direction of an arrow in FIG. 5B ), the lower stage internal ratchet teeth 29 and the lower stage external ratchet teeth 17 engage with each other to apply force to prevent turning in the opening direction. Meanwhile, when the nozzle cap 2 is operated to turn in the opening direction against the force, the joining sections 41 are easily broken to allow the nozzle cap 2 to be removed from the container main body 1 .
  • the nozzle cap 2 without the sealing ring part 23 is operated to turn in the closing direction to close the container main body 1 .
  • the cap 3 when the cap 3 is turned in the opening direction (in a counterclockwise direction viewed from above), the upper stage internal ratchet teeth 28 and the upper stage external ratchet teeth 16 engage with each other to apply force to prevent turning in the opening direction (in the direction of an arrow of FIG. 6B ). Therefore, even when the cap 3 is operated to turn in the opening direction, the closed state between the nozzle cap 2 and the container main body 1 is kept, which makes it possible to remove only the cap 3 .
  • the body section 11 of the container main body 1 is filled with a first ingredient, and thereafter, the female screw 27 of the body section 22 of the nozzle cap 2 is screwed together with the male screw 13 of the container main body 1 to be operated to turn in the closing direction, to allow the nozzle cap 2 to be screwed onto the container main body 1 .
  • the turning operation is terminated when the sealing ring part 23 is turned up to a predetermined position shown in FIG. 5A and the lower stage internal ratchet teeth 29 and the lower stage external ratchet teeth 17 engage with each other.
  • the body section 22 may be excessively turned to break the joining sections 41 .
  • the front end of the downward protruding piece 42 comes into contact with the rear end of the upward protruding piece 43 to regulate excessive turning of the body section 22 , to perform an appropriate turning operation.
  • the present invention is not limited to only the above-described embodiment.
  • the two-drug pharmaceutical container is configured so that only the lower stage internal and external ratchet teeth 17 and 29 engage with each other to prevent turning in the opening direction in a closed state before use, and is configured so that the upper stage internal and external ratchet teeth 16 and 28 engage with each other to prevent turning in the opening direction in a state in which the container main body is closed with the nozzle cap 2 without the sealing ring part 23 , the shapes, the numbers of teeth, the pitches, the positional relationships of height or the like, and the like of the upper and lower stage and internal and external ratchet teeth can be appropriately changed.
  • the present invention may have broad applicability as a two-drug pharmaceutical container in which its container main body and nozzle cap are not loosened before use, and when the cap is turned in the opening direction at the time of administering eye drops or the like, the nozzle cap and the container main body are not loosened to keep the closed state, which makes it possible to remove only the cap.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
US13/260,579 2009-04-02 2010-04-01 Two-drug pharmaceutical container Abandoned US20120018318A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009-090182 2009-04-02
JP2009090182 2009-04-02
PCT/JP2010/056028 WO2010114100A1 (ja) 2009-04-02 2010-04-01 二剤性医薬用容器

Publications (1)

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US20120018318A1 true US20120018318A1 (en) 2012-01-26

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US13/260,579 Abandoned US20120018318A1 (en) 2009-04-02 2010-04-01 Two-drug pharmaceutical container

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US (1) US20120018318A1 (de)
EP (1) EP2415686A4 (de)
JP (1) JPWO2010114100A1 (de)
KR (1) KR20120008021A (de)
CN (1) CN102378723A (de)
CA (1) CA2757299A1 (de)
TW (1) TW201102057A (de)
WO (1) WO2010114100A1 (de)

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WO2013139352A1 (en) * 2012-03-22 2013-09-26 Aptar Freyung Gmbh Container with a dispensing closure and dispensing closure for a container
US9604012B2 (en) 2011-04-20 2017-03-28 Taisei Kako Co., Ltd. Barrel with cap, pre-filled syringe, and cap with connector
US20180127172A1 (en) * 2015-04-28 2018-05-10 Nemera La Verpillière S.A.S. Device For Closing A Container By Screwing, Secured By A Retractable Lug
US20220330621A1 (en) * 2017-02-02 2022-10-20 Rai Strategic Holdings, Inc. Dispenser unit for aerosol precursor

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JP5961968B2 (ja) * 2011-09-29 2016-08-03 凸版印刷株式会社 二重キャップ付き口栓およびパウチ
JP5933314B2 (ja) * 2012-03-30 2016-06-08 株式会社吉野工業所 混合容器用キャップ
JP6076060B2 (ja) * 2012-12-03 2017-02-08 旭化成メディカル株式会社 医療用容器
CN103264805A (zh) * 2013-04-24 2013-08-28 苏州市锦新医用塑料容器厂 一种瓶子
KR101598995B1 (ko) 2014-07-10 2016-03-03 강릉원주대학교산학협력단 와이어 위치 감지장치
EP3323448A1 (de) * 2016-11-18 2018-05-23 Carebay Europe Ltd. Medikamentenabgabevorrichtung
CN207595608U (zh) * 2017-06-22 2018-07-10 柏美远东有限公司 螺纹接合机构及容器
DE202022106996U1 (de) * 2022-12-14 2023-01-11 Neutec Chemie Gmbh Produktaufnahmebehälter mit Gewindeadapter

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CN102378723A (zh) 2012-03-14
CA2757299A1 (en) 2010-10-07
TW201102057A (en) 2011-01-16
EP2415686A1 (de) 2012-02-08
WO2010114100A1 (ja) 2010-10-07
KR20120008021A (ko) 2012-01-25
JPWO2010114100A1 (ja) 2012-10-11
EP2415686A4 (de) 2012-08-15

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