US20040105798A1 - Sterilizing tunnel for pharmaceutical containers - Google Patents

Sterilizing tunnel for pharmaceutical containers Download PDF

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Publication number
US20040105798A1
US20040105798A1 US10/470,343 US47034304A US2004105798A1 US 20040105798 A1 US20040105798 A1 US 20040105798A1 US 47034304 A US47034304 A US 47034304A US 2004105798 A1 US2004105798 A1 US 2004105798A1
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US
United States
Prior art keywords
containers
heating
sterilizing tunnel
zone
sterilizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/470,343
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English (en)
Inventor
Manfred Windsheimer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7707376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US20040105798(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Assigned to ROBERT BOSCH GMBH reassignment ROBERT BOSCH GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: WINDSHEIMER, MANFRED
Publication of US20040105798A1 publication Critical patent/US20040105798A1/en
Priority to US12/007,499 priority Critical patent/US8501110B2/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/085Infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04Heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02Sterilising, e.g. of complete packages
    • B65B55/025Packaging in aseptic tunnels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02Sterilising, e.g. of complete packages
    • B65B55/04Sterilising wrappers or receptacles prior to, or during, packaging
    • B65B55/08Sterilising wrappers or receptacles prior to, or during, packaging by irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/23Containers, e.g. vials, bottles, syringes, mail

Definitions

  • the invention relates to a sterilizing tunnel for pharmaceutical containers as generically defined by the preamble to claim 1 , of the type that is known from DE 198 46 277 C2.
  • Sterilizing tunnels of this kind which are used in the pharmaceutical industry, particularly for sterilizing ampules, vials, or the like, have ventilating fans in the individual zones along which the containers are conveyed, which produce an air flow that circulates around the containers in a laminar fashion from top toward the bottom.
  • the circulated air is scrubbed by means of clean air filters (so-called HEPA filters) disposed above the containers and is heated and cooled by means of heating and cooling units.
  • HEPA filters clean air filters
  • the heating and cooling of the containers occurs from the direction of the container mouth toward the container bottom, i.e. unevenly over the height of the container, which can damage the containers or produce stress cracks in them, particularly in relatively thin containers or when a container has walls of different thicknesses.
  • the sterilizing tunnel for pharmaceutical containers according to the invention has the advantage over the prior art that the containers are thermally treated in a particularly gentle way so that the probability of stress cracks is reduced. This is achieved according to the invention through the additional use of radiant heat-generating heating units that act on the container bottoms so that in concert with the hot air from the ventilating fan units, it is possible to produce a uniform heating of the containers over their entire height.
  • the transport apparatus on which the containers are conveyed is embodied in the form of a radiation-permeable wire mesh belt.
  • the sterilizing tunnel is also intended to be used for coating and baking-on emulsion-like substances
  • the invention provides for the use of heating units that generate additional radiant heat in the heating zone, which units are disposed above and/or to the side of the containers.
  • the coating and baking-on process is at least for the most part already finished by the next time hot air is circulated around the containers, thus reducing the percentage of baking residues in the air that is circulated through the filters.
  • FIG. 1 shows a simplified longitudinal section through a first sterilizing tunnel according to the invention
  • FIG. 2 shows a partial section in the plane II-II of FIG. 1 during operation of the first sterilizing tunnel
  • FIG. 3 shows a simplified longitudinal section through a second sterilizing tunnel according to the invention.
  • FIG. 4 shows a partial section in the plane IV-IV of FIG. 3 during operation of the second sterilizing tunnel.
  • the first sterilizing tunnel 10 is essentially comprised of an entry zone 11 , a heating zone 12 , and two cooling zones 13 , 14 .
  • Pharmaceutical containers 1 such as ampules, vials, or the like, which come from a cleaning machine, not shown, are supplied into the sterilizing tunnel 10 from the entry zone 11 and leave the tunnel at its opposite end 15 after the cooling zone 14 , in order to then be further processed in the subsequent filling and closing machines, which are not shown.
  • a horizontal, preferably continuously driven, endless conveyor belt 17 serves to transport the containers 1 through the individual zones inside the sterilizing tunnel 10 .
  • the conveyor belt 17 is embodied as an air-permeable wire mesh belt made of stainless steel.
  • Large-area filter elements 18 , 19 , and 20 are disposed above the conveyor belt 17 in the different zones of the sterilizing tunnel 10 .
  • the filter elements 18 , 19 , and 20 cooperate with ventilating fan units 22 , 23 , and 24 , which are each associated with a respective zone and each serve to circulate the air in a respectively closed circuit.
  • the air flows generated by the ventilating fan units 22 , 23 , and 24 which circulate in the form of so-called laminar flow currents (flow arrows 25 ) around the containers 1 essentially from top to bottom during their transport through the sterilizing tunnel 10 , are temperature-controlled by means of heating and cooling units that are not shown.
  • temperature sensors are placed in the individual zones, which supply the measured temperatures as input values to the control unit of the sterilizing tunnel 10 .
  • the control unit then appropriately regulates the heating and cooling units, and is assisted by inlet and outlet air flaps, not shown, that are also disposed in the zones, which additionally serve to compensate for leakage and overflow losses.
  • vertically adjustable sluices 26 , 27 , and 28 whose position is adapted to the respective container height, are positioned both between zones and within zones in order to reduce the above-mentioned overflow losses between the individual zones.
  • the air flows generated by the ventilating fan units 22 , 23 , and 24 which circulate around the containers 1 from above, i.e. from the container mouth 2 toward the container bottom 3 , result in an uneven temperature distribution over the height of the containers.
  • the container mouths 2 have a higher temperature than the container bottoms 3 as they pass through the heating zone 12 . This is because the hot air in the heating zone 12 comes into contact with the container mouth 2 first.
  • the sterilizing tunnel 10 is particularly designed to permit deliberate influence to be exerted on the temperature distribution along the height of the containers 1 in order to thus prevent thermal stresses that can damage the containers 1 and is also designed to permit favorable influence to be exerted on the baking of emulsion-like particles into the inner walls of the containers.
  • the heating zone 12 is divided into two regions 33 and 34 by means of a dividing wall 31 , whose end oriented toward the conveyor belt 17 is embodied as a vertically adjustable intermediary way 32 .
  • the ventilating fan unit 22 provides a heated air flow
  • the other region 34 situated on the side oriented toward the entry zone 11 is provided with a number of radiant heat-generating heating units 35 , 36 , 37 .
  • the heating units 36 , 36 , 37 which are in particular embodied in the form of infrared radiators and in the exemplary embodiment are embodied as rod-shaped, are disposed underneath the radiation-permeable conveyor belt 17 close to the container bottoms 3 , above the conveyor belt 17 close to the container mouths 2 , and if need be, beside the conveyor belt 17 at the same height as the container mouths 2 outside of stationary or mobile lateral guides 38 for the conveyor belt 17 ; in the exemplary embodiment, the heating units 35 , 36 extend lateral to the travel direction of the containers 1 through the sterilizing tunnel 10 and the heating units 37 extend along this travel direction. Furthermore, in the region 34 , there is also at least one temperature sensor 39 , which is coupled to the control unit of the sterilizing tunnel 10 .
  • the heating units 35 , 36 , 37 make it possible to provide an intentionally more intense preheating of particular container regions, for example the container bottoms 3 , in order to prevent thermal stresses in the containers 1 in the subsequent further heating by means of the air flow in region 33 .
  • the heating units 35 oriented toward the container bottoms 3 are set to a higher temperature than the other heating units 36 , 37 .
  • the radiant heat of the heating units 35 , 36 , 37 can also be set very aggressively, i.e. a temperature inside the containers 1 , which is required for coating them, is reached within an extremely short period of time and is then reduced again if need be in the region 33 .
  • the heating zone 12 is only provided with additional heating units 35 underneath the radiation-permeable conveyor belt 17 and with heating units 37 disposed to the side, outside the lateral guides 38 in a manner analogous to the sterilizing tunnel 10 , but no radiant heat-generating heating units are provided above the containers 1 . Instead, the containers 1 are heated with hot air from above by means of the ventilating fan unit 22 in the entire heating zone 12 , from which it also follows that the sterilizing tunnel 10 a does not contain a dividing wall 31 of the type provided in the sterilizing tunnel 10 that divides the heating zone 12 into different regions.
  • the first cooling zone 13 is provided with additional heating units 40 , 41 , which also generate radiant heat.
  • These heating units 40 , 41 which are also rod-shaped, are provided above the container mouths 2 on the side oriented toward the heating zone 12 , as well as laterally, outside the lateral guides 38 , at the same height as the container mouths 2 , and are controlled by means of a temperature sensor, not shown, which is disposed in the cooling zone 13 close to the heating units 40 and is coupled to the control unit of the sterilizing tunnel 10 .
  • the heating units 40 , 41 make it possible for the containers 1 , which are transferred out of the heating zone 12 and have a relatively high temperature, to be cooled down somewhat less rapidly in the vicinity of their container mouths 2 , thus permitting a more uniform cooling of the containers 1 on the whole.
  • the arrangement of additional heating units 35 , 37 , 40 , 41 embodied in the sterilizing tunnel 10 a consequently makes it possible to achieve a heating and cooling of the containers 1 that is gentle to the material in order to avoid thermal stresses and prevent heat cracks in the containers 1 .
  • the two sterilizing tunnels 10 , 10 a according to the invention can be modified in numerous ways without going beyond essence of the invention, which is comprised of providing additional radiant heat-generating heating units in the sterilizing tunnel 10 , which in cooperation with air flows generated by the ventilation fan units, produce a uniform heating and uniform cooling of the containers 1 . It is therefore conceivable, for example, to omit the heating units 36 , 37 at the top and at the sides. Furthermore, the sterilizing tunnel 10 can also have the heating units 40 , 41 disposed in the cooling zone 13 of the sterilizing tunnel 10 a , in order to treat the containers 1 in a particularly gentle fashion with regard to thermal stresses.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
US10/470,343 2001-11-29 2002-07-30 Sterilizing tunnel for pharmaceutical containers Abandoned US20040105798A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/007,499 US8501110B2 (en) 2001-11-29 2008-01-11 Sterilizing tunnel for pharmaceutical containers

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10158571A DE10158571A1 (de) 2001-11-29 2001-11-29 Sterilisiertunnel für pharmazeutische Behältnisse
DE10158571.3 2001-11-29
PCT/DE2002/002793 WO2003047637A1 (fr) 2001-11-29 2002-07-30 Tunnel sterilisateur pour recipients pharmaceutiques

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/007,499 Division US8501110B2 (en) 2001-11-29 2008-01-11 Sterilizing tunnel for pharmaceutical containers

Publications (1)

Publication Number Publication Date
US20040105798A1 true US20040105798A1 (en) 2004-06-03

Family

ID=7707376

Family Applications (2)

Application Number Title Priority Date Filing Date
US10/470,343 Abandoned US20040105798A1 (en) 2001-11-29 2002-07-30 Sterilizing tunnel for pharmaceutical containers
US12/007,499 Expired - Fee Related US8501110B2 (en) 2001-11-29 2008-01-11 Sterilizing tunnel for pharmaceutical containers

Family Applications After (1)

Application Number Title Priority Date Filing Date
US12/007,499 Expired - Fee Related US8501110B2 (en) 2001-11-29 2008-01-11 Sterilizing tunnel for pharmaceutical containers

Country Status (5)

Country Link
US (2) US20040105798A1 (fr)
EP (1) EP1450867B2 (fr)
JP (1) JP4388815B2 (fr)
DE (2) DE10158571A1 (fr)
WO (1) WO2003047637A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080260609A1 (en) * 2005-01-12 2008-10-23 Claudio Bechini Unit for Sterilising and Depyrogenating Containers
US10350139B2 (en) * 2011-10-25 2019-07-16 Corning Incorporated Pharmaceutical glass packaging assuring pharmaceutical sterility

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10158571A1 (de) 2001-11-29 2003-06-12 Bosch Gmbh Robert Sterilisiertunnel für pharmazeutische Behältnisse
DE102007050999B4 (de) 2007-10-25 2017-02-23 Robert Bosch Gmbh Sterilisiertunnel für pharmazeutische Behältnisse
WO2011002380A1 (fr) * 2009-07-03 2011-01-06 Tetra Laval Holdings & Finance S.A. Dispositif et procédé pour la stérilisation d'emballages
DE102013204668A1 (de) * 2012-04-05 2013-10-10 Robert Bosch Gmbh Verfahren und Vorrichtung zum Kühlen von zuvor sterilisierten pharmazeutischen Behältern
WO2014071117A1 (fr) * 2012-11-01 2014-05-08 Covidien Lp Système et procédé de traitement d'une surface d'un dispositif d'injection
CN103170000A (zh) * 2013-03-29 2013-06-26 施佳卫 一种气体过滤杀菌装置
CN103212104A (zh) * 2013-03-29 2013-07-24 施佳卫 一种气体杀菌装置
CN103169991A (zh) * 2013-03-29 2013-06-26 张玉方 一种高温杀菌装置
ITPR20130031A1 (it) * 2013-04-05 2014-10-06 One Love Di Tarasconi Ermina & C S A S Impianto di sterilizzazione
ITUD20130064A1 (it) 2013-05-13 2014-11-14 Steelco Spa Macchina a tunnel per il lavaggio di oggetti
EP3043831A1 (fr) 2013-09-09 2016-07-20 Covidien LP Dispositif à usage unique pour l'injection de médicaments en cartouche
DE102014200145A1 (de) * 2014-01-08 2015-07-09 Robert Bosch Gmbh Transporteinrichtung zum Transportieren von Behältnissen mit verbesserter Seitenführung
US10588786B2 (en) * 2016-05-19 2020-03-17 The Procter & Gamble Company Method and apparatus for microwave product treatment
JP6533775B2 (ja) * 2016-12-26 2019-06-19 チヨダエレクトリック株式会社 乾熱滅菌装置
JP7374899B2 (ja) 2017-12-11 2023-11-07 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド モジュール式無菌生産システム
US10864291B2 (en) * 2017-12-26 2020-12-15 Asp Global Manufacturing Gmbh Process and apparatus for cleaning, disinfection, sterilization, or combinations thereof
DE102020114221A1 (de) * 2020-05-27 2021-12-02 Syntegon Technology Gmbh Vorrichtung und Verfahren zum schlagartigen Sterilisieren

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4727800A (en) * 1985-05-28 1988-03-01 Anheuser-Busch, Incorporated Pasteurization apparatus
US5022165A (en) * 1990-06-29 1991-06-11 The West Company, Incorporated Sterilization tunnel
US5064614A (en) * 1987-10-14 1991-11-12 Hans Gilovyy Maschinenfabrik "Meteorwerk" Gmbh & Co. Method for sterilizing heat-tolerating containers under clean-room conditions
US6142065A (en) * 1998-05-29 2000-11-07 Sasib S.P.A. System for controlling the pasteurization heat treatment, in particular of packaged food products, in tunnel-type pasteurizers
US6413481B1 (en) * 1998-10-08 2002-07-02 Robert Bosch Gmbh Sterilization tunnel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1248234B (de) 1959-08-31 1967-08-24 Chirana Praha N P Automatischer Heissluftsterilisator
DE3321195A1 (de) * 1983-06-11 1984-12-13 Bayer Ag, 5090 Leverkusen Vorrichtung zur trockenhitzesterilisation von glasbehaeltnissen fuer parenterale arzneimittel
DE3506788A1 (de) 1985-02-22 1985-07-18 Detlef 1000 Berlin Güttschow Verfahren zum kontinuierlichen messen, steuern und regeln des temperaturverlaufs von behaeltnissen und zubehoer fuer parenterale arzneimittel
DE3510286A1 (de) 1985-03-19 1986-09-25 Hans Gilowy Maschinenfabrik "Meteorwerk" GmbH & Co, 1000 Berlin Verfahren zum betrieb von strahlungs-sterilisierapparaten und einrichtung zur durchfuehrung des verfahrens
DE8913860U1 (de) * 1989-11-24 1991-03-21 Robert Bosch Gmbh, 7000 Stuttgart Sterilisiervorrichtung für temperaturstabile Behältnisse
DE4131258A1 (de) 1991-09-17 1992-05-07 Siedler Torsten Temperatur- und stroemungsregelungsvorrichtung im sterilisierapparat
DE19804386C2 (de) * 1998-02-04 1999-12-30 Ttp Ingenieurbuero Verfahren und Vorrichtung zur Trocknung oder Wärmebehandlung von Produkten, insbesondere mit Hilfe von Mikrowellenstrahlung, und damit hergestellte Bananenchips und Bananenpulver
DE10158571A1 (de) 2001-11-29 2003-06-12 Bosch Gmbh Robert Sterilisiertunnel für pharmazeutische Behältnisse

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4727800A (en) * 1985-05-28 1988-03-01 Anheuser-Busch, Incorporated Pasteurization apparatus
US5064614A (en) * 1987-10-14 1991-11-12 Hans Gilovyy Maschinenfabrik "Meteorwerk" Gmbh & Co. Method for sterilizing heat-tolerating containers under clean-room conditions
US5022165A (en) * 1990-06-29 1991-06-11 The West Company, Incorporated Sterilization tunnel
US6142065A (en) * 1998-05-29 2000-11-07 Sasib S.P.A. System for controlling the pasteurization heat treatment, in particular of packaged food products, in tunnel-type pasteurizers
US6413481B1 (en) * 1998-10-08 2002-07-02 Robert Bosch Gmbh Sterilization tunnel

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080260609A1 (en) * 2005-01-12 2008-10-23 Claudio Bechini Unit for Sterilising and Depyrogenating Containers
US7811533B2 (en) * 2005-01-12 2010-10-12 I.M.A. Industria Macchine Automatiche S.P.A. Unit for sterilising and depyrogenating containers
US10350139B2 (en) * 2011-10-25 2019-07-16 Corning Incorporated Pharmaceutical glass packaging assuring pharmaceutical sterility

Also Published As

Publication number Publication date
WO2003047637A1 (fr) 2003-06-12
US8501110B2 (en) 2013-08-06
JP2005511145A (ja) 2005-04-28
US20080181826A1 (en) 2008-07-31
EP1450867A1 (fr) 2004-09-01
EP1450867B2 (fr) 2013-09-11
DE10158571A1 (de) 2003-06-12
EP1450867B1 (fr) 2008-02-27
DE50211799D1 (de) 2008-04-10
JP4388815B2 (ja) 2009-12-24

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Legal Events

Date Code Title Description
AS Assignment

Owner name: ROBERT BOSCH GMBH, GERMANY

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:WINDSHEIMER, MANFRED;REEL/FRAME:014253/0193

Effective date: 20030825

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION