UA97161C2 - Фармацевтическая композиция, которая содержит дигидропиридиновый антагонист кальциевого канала лерканидипин и коллоидный диоксид кремния, способ ее приготовления - Google Patents
Фармацевтическая композиция, которая содержит дигидропиридиновый антагонист кальциевого канала лерканидипин и коллоидный диоксид кремния, способ ее приготовленияInfo
- Publication number
- UA97161C2 UA97161C2 UAA201001781A UAA201001781A UA97161C2 UA 97161 C2 UA97161 C2 UA 97161C2 UA A201001781 A UAA201001781 A UA A201001781A UA A201001781 A UAA201001781 A UA A201001781A UA 97161 C2 UA97161 C2 UA 97161C2
- Authority
- UA
- Ukraine
- Prior art keywords
- heading
- preparation
- calcium channel
- channel antagonist
- normal
- Prior art date
Links
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical compound C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title abstract 2
- 229940127291 Calcium channel antagonist Drugs 0.000 title abstract 2
- 239000000480 calcium channel blocker Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 229940075614 colloidal silicon dioxide Drugs 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- ZDXUKAKRHYTAKV-UHFFFAOYSA-N lercanidipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)(C)CN(C)CCC(C=2C=CC=CC=2)C=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 ZDXUKAKRHYTAKV-UHFFFAOYSA-N 0.000 abstract 1
- 229960004294 lercanidipine Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007909 solid dosage form Substances 0.000 abstract 1
- 238000005550 wet granulation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2007/006517 WO2009012791A1 (en) | 2007-07-23 | 2007-07-23 | Pharmaceutical composition containing dihydropyridine calcium channel antagonist and method for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA97161C2 true UA97161C2 (ru) | 2012-01-10 |
Family
ID=39223083
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201001781A UA97161C2 (ru) | 2007-07-23 | 2007-07-23 | Фармацевтическая композиция, которая содержит дигидропиридиновый антагонист кальциевого канала лерканидипин и коллоидный диоксид кремния, способ ее приготовления |
| UAA201000447A UA99136C2 (ru) | 2007-07-23 | 2008-07-23 | Улучшенная фармацевтическая композиция, содержащая антагонист кальциевых каналов - лерканидипин, способ ее получения |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201000447A UA99136C2 (ru) | 2007-07-23 | 2008-07-23 | Улучшенная фармацевтическая композиция, содержащая антагонист кальциевых каналов - лерканидипин, способ ее получения |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP2180883B1 (enExample) |
| JP (2) | JP5769963B2 (enExample) |
| KR (2) | KR101632079B1 (enExample) |
| CN (3) | CN101784260A (enExample) |
| AU (2) | AU2007356942B2 (enExample) |
| BR (2) | BRPI0721883A2 (enExample) |
| CA (2) | CA2691752C (enExample) |
| CO (1) | CO6290639A2 (enExample) |
| CR (1) | CR11285A (enExample) |
| EA (2) | EA021645B1 (enExample) |
| EC (1) | ECSP109984A (enExample) |
| ES (2) | ES2622495T3 (enExample) |
| MA (1) | MA31684B1 (enExample) |
| MX (2) | MX2010000856A (enExample) |
| MY (1) | MY153857A (enExample) |
| NZ (2) | NZ582648A (enExample) |
| TN (2) | TN2010000011A1 (enExample) |
| UA (2) | UA97161C2 (enExample) |
| WO (2) | WO2009012791A1 (enExample) |
| ZA (2) | ZA201000586B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| JP2010533729A (ja) | 2007-07-17 | 2010-10-28 | プレキシコン，インコーポレーテッド | キナーゼ調節のための化合物と方法、及びそのための適応 |
| KR101632079B1 (ko) * | 2007-07-23 | 2016-06-20 | 파마덴 에스.에이. | 디히드로피리딘 칼슘 채널 길항제를 함유하는 약제학적 조성물 및 그것의 제조방법 |
| CA2738573C (en) | 2009-04-03 | 2013-02-19 | F. Hoffmann-La Roche Ag | Compositions of propane-1 sulfonic acid {3-[5-(4-chloro-phenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide and uses thereof |
| US8329724B2 (en) | 2009-08-03 | 2012-12-11 | Hoffmann-La Roche Inc. | Process for the manufacture of pharmaceutically active compounds |
| JP2013510166A (ja) | 2009-11-06 | 2013-03-21 | プレキシコン インコーポレーテッド | キナーゼ調節のための化合物、方法およびその適用 |
| PE20141360A1 (es) | 2011-02-07 | 2014-10-13 | Plexxikon Inc | Compuestos y metodos para la modulacion de quinasas e indicaciones para los mismos. |
| TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
| US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
| US10835495B2 (en) | 2012-11-14 | 2020-11-17 | W. R. Grace & Co.-Conn. | Compositions containing a biologically active material and a non-ordered inorganic oxide material and methods of making and using the same |
| GR1008554B (el) * | 2014-06-12 | 2015-09-03 | ΦΑΡΜΑΤΕΝ ΑΝΩΝΥΜΟΣ ΒΙΟΜΗΧΑΝΙΚΗ ΚΑΙ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΕΙΑ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΙΑΤΡΙΚΩΝ ΚΑΙ ΚΑΛΛΥΝΤΙΚΩΝ ΠΡΟΪΟΝΤΩΝ με δ.τ. ΦΑΡΜΑΤΕΝ, | Φαρμακευτικο σκευασμα περιεχον εναν αντιμυκητιασικο παραγοντα τριaζολης και μεθοδος για την παρασκευη αυτου |
| CN104069500A (zh) * | 2014-06-20 | 2014-10-01 | 湖南天地恒一制药有限公司 | 一种包含乐卡地平的药物组合物 |
| CN105168165B (zh) * | 2015-08-28 | 2018-06-26 | 江苏福邦药业有限公司 | 一种盐酸乐卡地平片及其制备方法 |
| WO2018004379A1 (ru) * | 2016-07-01 | 2018-01-04 | Общество С Ограниченной Ответственностью "Гиостин" | Средство в виде капсулы для лечения заболеваний суставов |
| WO2019165420A1 (en) | 2018-02-26 | 2019-08-29 | R.P. Scherer Technologies, Llc | Pharmaceutical dosage form for an emulsion of simethicone and loperamide |
| CA3094115A1 (en) | 2018-03-22 | 2019-09-26 | Komipharm International Australia Pty Ltd | Pharmaceutical composition comprising meta arsenite and method of manufacture |
| JP2023107429A (ja) * | 2022-01-24 | 2023-08-03 | 東芝テック株式会社 | 読取装置 |
| CN114533686B (zh) * | 2022-02-15 | 2023-10-20 | 湖南普道医药技术有限公司 | 一种二氢吡啶类药物的口服固体制剂及其制备方法 |
| KR20240040407A (ko) * | 2022-09-21 | 2024-03-28 | 주식회사 종근당 | 사쿠비트릴ㆍ발사르탄 칼슘염을 포함하는 약제학적 조성물 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3720757A1 (de) * | 1987-06-24 | 1989-01-05 | Bayer Ag | Dhp-manteltablette |
| US5209933A (en) * | 1990-01-10 | 1993-05-11 | Syntex (U.S.A.) Inc. | Long acting calcium channel blocker composition |
| GB9025251D0 (en) * | 1990-11-20 | 1991-01-02 | Solomon Montague C | Nifedipine dosage forms |
| BR9903490A (pt) * | 1998-12-15 | 2000-09-26 | Oscar Gold | Processo para a preparação de composições farmacêuticas de liberação programada contendo nimodipine, que permitem a liberação gradual e a manuntenção da ação terapeutica |
| DE19944803A1 (de) * | 1999-09-20 | 2001-03-29 | Bayer Ag | Kombination von Dihydropyridinverbindungen und HMG-CoA-Reduktase-Inhibitoren und ihre Verwendung in Arzneimitteln |
| US20040185097A1 (en) * | 2003-01-31 | 2004-09-23 | Glenmark Pharmaceuticals Ltd. | Controlled release modifying complex and pharmaceutical compositions thereof |
| EP1694305B1 (en) * | 2003-12-01 | 2019-10-16 | Recordati Ireland Limited | Pharmaceutical compositions comprising lercanidipine |
| UA89177C2 (ru) * | 2003-12-01 | 2010-01-11 | Рекордати Айрленд Лимитед | Фармацевтическая композиция с контролируемым высвобождением, которая содержит лерканидипин |
| EP2063872B2 (en) * | 2006-08-30 | 2019-12-04 | Jagotec AG | Controlled release oral dosage formulations comprising a core and one or more barrier layers |
| WO2008068777A2 (en) * | 2006-12-06 | 2008-06-12 | Torrent Pharmaceuticals Limited | Stable lercanidipine formulation |
| KR101632079B1 (ko) * | 2007-07-23 | 2016-06-20 | 파마덴 에스.에이. | 디히드로피리딘 칼슘 채널 길항제를 함유하는 약제학적 조성물 및 그것의 제조방법 |
-
2007
- 2007-07-23 KR KR1020107001425A patent/KR101632079B1/ko active Active
- 2007-07-23 CA CA2691752A patent/CA2691752C/en active Active
- 2007-07-23 UA UAA201001781A patent/UA97161C2/ru unknown
- 2007-07-23 BR BRPI0721883-4A2A patent/BRPI0721883A2/pt not_active IP Right Cessation
- 2007-07-23 EA EA201070160A patent/EA021645B1/ru not_active IP Right Cessation
- 2007-07-23 ES ES07786262.1T patent/ES2622495T3/es active Active
- 2007-07-23 JP JP2010517273A patent/JP5769963B2/ja not_active Expired - Fee Related
- 2007-07-23 AU AU2007356942A patent/AU2007356942B2/en active Active
- 2007-07-23 CN CN200780100025A patent/CN101784260A/zh active Pending
- 2007-07-23 EP EP07786262.1A patent/EP2180883B1/en active Active
- 2007-07-23 MX MX2010000856A patent/MX2010000856A/es active IP Right Grant
- 2007-07-23 WO PCT/EP2007/006517 patent/WO2009012791A1/en not_active Ceased
- 2007-07-23 NZ NZ582648A patent/NZ582648A/en unknown
-
2008
- 2008-07-23 JP JP2010517393A patent/JP2010534220A/ja active Pending
- 2008-07-23 MX MX2010000801A patent/MX2010000801A/es active IP Right Grant
- 2008-07-23 KR KR1020107002430A patent/KR101512404B1/ko not_active Expired - Fee Related
- 2008-07-23 ES ES08775312.5T patent/ES2537063T3/es active Active
- 2008-07-23 WO PCT/EP2008/059645 patent/WO2009013306A1/en not_active Ceased
- 2008-07-23 EP EP20080775312 patent/EP2170295B1/en active Active
- 2008-07-23 AU AU2008280106A patent/AU2008280106B9/en not_active Ceased
- 2008-07-23 NZ NZ582690A patent/NZ582690A/en not_active IP Right Cessation
- 2008-07-23 EA EA201000220A patent/EA019614B1/ru unknown
- 2008-07-23 CN CN200880100075A patent/CN101801347A/zh active Pending
- 2008-07-23 BR BRPI0814666A patent/BRPI0814666A2/pt not_active IP Right Cessation
- 2008-07-23 UA UAA201000447A patent/UA99136C2/ru unknown
- 2008-07-23 CN CN201410243247.6A patent/CN103976968A/zh active Pending
- 2008-07-23 CA CA2693233A patent/CA2693233A1/en not_active Abandoned
- 2008-07-23 MY MYPI2010000318A patent/MY153857A/en unknown
-
2010
- 2010-01-08 TN TNP2010000011A patent/TN2010000011A1/fr unknown
- 2010-01-13 TN TNP2010000022A patent/TN2010000022A1/fr unknown
- 2010-01-20 CO CO10005281A patent/CO6290639A2/es not_active Application Discontinuation
- 2010-01-26 ZA ZA2010/00586A patent/ZA201000586B/en unknown
- 2010-02-17 MA MA32628A patent/MA31684B1/fr unknown
- 2010-02-18 ZA ZA2010/01176A patent/ZA201001176B/en unknown
- 2010-02-19 CR CR11285A patent/CR11285A/es unknown
- 2010-02-23 EC EC2010009984A patent/ECSP109984A/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TN2010000022A1 (en) | Pharmaceutical composition containing dihydropyridine calcium channel antagonist and method for the preparation thereof | |
| EA018193B3 (ru) | Соединения и фармацевтические композиции для снижения уровня мочевой кислоты | |
| JO2973B1 (en) | Fumarate salt for (alpha-beta-R) -6-bromo-alpha-[2- (methylamino) ethyl-2-methoxy-alpha-1-naphthalenyl-beta-phenyl-3-quinoline ethanol | |
| IL193252A0 (en) | N-hydroxyacrylamide compounds | |
| WO2007113202A8 (en) | Piperazine derivatives as growth hormone secretagogue (ghs) receptor agonists | |
| PH12017501397B1 (en) | (2s, 4r)-5-(5`-chloro-2`-fluorobiphenyl-4-yl)-4-(ethoxyoxalylamino)-2-hydroxymethyl-2-methylpentanoic acid as neprilysin inhibitor | |
| MX2009008463A (es) | Formulaciones biodisponibles de compuestos heterociclicos. | |
| ZA201003380B (en) | Improved pharmaceutical composition containing a pyrrolidone anticonvulsant agent and methhod for the preparation thereof | |
| WO2008081268A3 (en) | Pharmaceutical compositions of entacapone | |
| WO2007110765A3 (en) | Processes for the preparation of octreotide | |
| MX2007010400A (es) | Nuevas sales de derivados de hexahidrofenantridina sustituida con 6-heterociclilo. | |
| GR1008821B (el) | Φαρμακευτικο σκευασμα που περιλαμβανει υδροχλωρικη ιβαμπραδινη και μεθοδος παρασκευης αυτου | |
| GR20070100405A (el) | Βελτιωμενες φαρμακοτεχνικες μορφες που περιεχουν αναστολεις της ακετυλοχοληνεστερασης και μεθοδοι παρασκευης αυτων | |
| WO2007138462A3 (en) | Aqueous oral formulations of risperidone | |
| WO2003070153A3 (en) | Stabilized pharmaceutical compositions of halofuginone and other quinazolinone derivatives | |
| UA93355C2 (ru) | Композиция субероиланилид-гидроксаминовой кислоты и способы ee получения | |
| MY150480A (en) | Pharmaceutical composition containing dihydropyridine calcium channel antagonist and method for the preparation thereof | |
| UA95274C2 (ru) | Твердый фармацевтический препарат, содержащий ирбесартан, и способы его изготовления | |
| WO2008068569A3 (en) | Processes for the preparation of clopidogrel hydrochloride | |
| CY1108846T1 (el) | Βελτιωμενη φαρμακευτικη συνθεση που περιεχει αναστολεα ace και μεθοδος για την παρασκευη της | |
| WO2007102171A3 (en) | Novel salts of 1h-1-benzazepine-1-acetic acid, their preparation and pharmaceutical composition | |
| WO2005085240A3 (en) | Process for the preparation of ziprasidone | |
| WO2007052167A3 (en) | Stable composition for a pharmaceutical formulation containing olanzapine | |
| PL374489A1 (en) | Novel substituted arylhexadienoic acids and esters thereof which can be used for the treatment and prevention of diabetes, dyslipidaemia and atherosclerosis, pharmaceutical compositions comprising them and processes for the preparation of them | |
| WO2010046912A3 (en) | Thiophene containing analogues of fluconazole as antifungal agents and process for their preparation |