WO2010070677A3 - A process for the preparation of prasugrel and its pharmaceutically acceptable salts thereof - Google Patents

A process for the preparation of prasugrel and its pharmaceutically acceptable salts thereof Download PDF

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Publication number
WO2010070677A3
WO2010070677A3 PCT/IN2009/000714 IN2009000714W WO2010070677A3 WO 2010070677 A3 WO2010070677 A3 WO 2010070677A3 IN 2009000714 W IN2009000714 W IN 2009000714W WO 2010070677 A3 WO2010070677 A3 WO 2010070677A3
Authority
WO
WIPO (PCT)
Prior art keywords
prasugrel
pharmaceutically acceptable
preparation
acceptable salts
relates
Prior art date
Application number
PCT/IN2009/000714
Other languages
French (fr)
Other versions
WO2010070677A2 (en
Inventor
Khan Mubeen Ahmed
Srinivas Reddy Sanikommu
Bhaskar Rao Antyakula Pydi
Shankar Sanganabhatla
Original Assignee
Glenmark Generics Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Generics Limited filed Critical Glenmark Generics Limited
Publication of WO2010070677A2 publication Critical patent/WO2010070677A2/en
Publication of WO2010070677A3 publication Critical patent/WO2010070677A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Abstract

The present invention relates to processes for the preparation of prasugrel and its pharmaceutically acceptable salts, including novel crystalline forms of prasugrel hydrochloride, and pharmaceutical compositions thereof. The present invention also relates to solid state properties of prasugrel or a pharmaceutically acceptable salt thereof.
PCT/IN2009/000714 2008-12-15 2009-12-09 A process for the preparation of prasugrel and its pharmaceutically acceptable salts thereof WO2010070677A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IN2609/MUM/2008 2008-12-15
IN2609MU2008 2008-12-15
IN343/MUM/2009 2009-02-17
IN343MU2009 2009-02-17
IN1248MU2009 2009-05-14
IN1248/MUM/2009 2009-05-14

Publications (2)

Publication Number Publication Date
WO2010070677A2 WO2010070677A2 (en) 2010-06-24
WO2010070677A3 true WO2010070677A3 (en) 2011-02-24

Family

ID=42269188

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2009/000714 WO2010070677A2 (en) 2008-12-15 2009-12-09 A process for the preparation of prasugrel and its pharmaceutically acceptable salts thereof

Country Status (1)

Country Link
WO (1) WO2010070677A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2469883A (en) * 2009-04-30 2010-11-03 Sandoz Ag Novel crystalline form of Prasugrel hydrogensulphate
DE102009036646A1 (en) * 2009-08-07 2011-02-10 Ratiopharm Gmbh Prasugrel in non-crystalline form and pharmaceutical composition thereof
ES2533681T3 (en) 2010-04-08 2015-04-14 Teva Pharmaceutical Industries Ltd. Crystal forms of Prasugrel salts
WO2012023145A2 (en) * 2010-08-18 2012-02-23 Hetero Research Foundation Prasugrel hydrochloride crystalline particles
CN102838618A (en) 2011-06-22 2012-12-26 广东东阳光药业有限公司 Method for preparing prasugrel, and prasugrel hydrochloride novel crystal forms
US8603537B2 (en) 2012-04-02 2013-12-10 Egis Pharmaceuticals Plc Prasugrel containing quickly released stable oral pharmaceutical compositions
PL402028A1 (en) 2012-12-12 2014-06-23 Instytut Farmaceutyczny Method for preparing polymorph B form of Prasugrel hydrochloride in pharmaceutical grade
CN103610674B (en) * 2013-12-09 2015-01-07 海南灵康制药有限公司 Solid preparation containing micronized prasugrel
CN117619352B (en) * 2024-01-26 2024-04-09 中国科学院合肥物质科学研究院 Degradation agent of perfluoro compound and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0542411A2 (en) * 1991-09-09 1993-05-19 Sankyo Company Limited Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation
EP0785205A1 (en) * 1994-10-07 1997-07-23 Ube Industries, Ltd. 2-silyloxytetrahydrothienopyridine, salt thereof, and process for producing the same
WO2007114526A1 (en) * 2006-04-06 2007-10-11 Daiichi Sankyo Company, Limited Process for producing high-purity prasugrel and acid addition salt thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0542411A2 (en) * 1991-09-09 1993-05-19 Sankyo Company Limited Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation
EP0785205A1 (en) * 1994-10-07 1997-07-23 Ube Industries, Ltd. 2-silyloxytetrahydrothienopyridine, salt thereof, and process for producing the same
WO2007114526A1 (en) * 2006-04-06 2007-10-11 Daiichi Sankyo Company, Limited Process for producing high-purity prasugrel and acid addition salt thereof

Also Published As

Publication number Publication date
WO2010070677A2 (en) 2010-06-24

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