CO6290639A2 - Composicion farmaceutica mejorada que contiene dihidropiridina antagonista del canal de calcio y el metodo para su preparacion - Google Patents

Composicion farmaceutica mejorada que contiene dihidropiridina antagonista del canal de calcio y el metodo para su preparacion

Info

Publication number
CO6290639A2
CO6290639A2 CO10005281A CO10005281A CO6290639A2 CO 6290639 A2 CO6290639 A2 CO 6290639A2 CO 10005281 A CO10005281 A CO 10005281A CO 10005281 A CO10005281 A CO 10005281A CO 6290639 A2 CO6290639 A2 CO 6290639A2
Authority
CO
Colombia
Prior art keywords
preparation
calcium channel
dihydropiridine
pharmaceutical composition
composition containing
Prior art date
Application number
CO10005281A
Other languages
English (en)
Inventor
Evangelos Karavas
Makis Koutris
Vicky Samara
Christina Matsingou
Athina Iliopoulou
Original Assignee
Pharmathen Sa
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39223083&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6290639(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmathen Sa, Recordati Ireland Ltd filed Critical Pharmathen Sa
Publication of CO6290639A2 publication Critical patent/CO6290639A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

La presente invención se refiere a la formulación de formas de dosificación sólidas que contienen una cantidad efectiva de una dihidropiridina antagonista del canal de calcio tal como Lercanidipina o una sal de esta, combinada con dióxido de silicio coloidal tal corno Aerosil para aumentar la biodisponibilidad y mejorar la solubilidad, y un proceso para su preparación por granulación húmeda.
CO10005281A 2007-07-23 2010-01-20 Composicion farmaceutica mejorada que contiene dihidropiridina antagonista del canal de calcio y el metodo para su preparacion CO6290639A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2007/006517 WO2009012791A1 (en) 2007-07-23 2007-07-23 Pharmaceutical composition containing dihydropyridine calcium channel antagonist and method for the preparation thereof

Publications (1)

Publication Number Publication Date
CO6290639A2 true CO6290639A2 (es) 2011-06-20

Family

ID=39223083

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10005281A CO6290639A2 (es) 2007-07-23 2010-01-20 Composicion farmaceutica mejorada que contiene dihidropiridina antagonista del canal de calcio y el metodo para su preparacion

Country Status (20)

Country Link
EP (2) EP2180883B1 (es)
JP (2) JP5769963B2 (es)
KR (2) KR101632079B1 (es)
CN (3) CN101784260A (es)
AU (2) AU2007356942B2 (es)
BR (2) BRPI0721883A2 (es)
CA (2) CA2691752C (es)
CO (1) CO6290639A2 (es)
CR (1) CR11285A (es)
EA (2) EA021645B1 (es)
EC (1) ECSP109984A (es)
ES (2) ES2622495T3 (es)
MA (1) MA31684B1 (es)
MX (2) MX2010000856A (es)
MY (1) MY153857A (es)
NZ (2) NZ582648A (es)
TN (2) TN2010000011A1 (es)
UA (2) UA97161C2 (es)
WO (2) WO2009012791A1 (es)
ZA (2) ZA201000586B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
BRPI0814423B1 (pt) 2007-07-17 2022-04-19 Plexxikon, Inc Compostos que modulam quinase e composição farmacêutica compreendendo os mesmos
EA021645B1 (ru) * 2007-07-23 2015-08-31 Фарматен С.А. Твердая дозированная форма в виде таблетки и способ её приготовления
CR20170089A (es) 2009-04-03 2017-07-17 Plexxikon Inc Composiciones del acido propano-1--sulfonico {3-[5-(4-cloro-fenil)-1h-pirrolo [2,3-b] piridina-3-carbonil] -2,4-difluoro-fenil}-amida y el uso de las mismas
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
WO2011057022A1 (en) 2009-11-06 2011-05-12 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
RS58455B1 (sr) 2011-02-07 2019-04-30 Plexxikon Inc Jedinjenja i postupci za modulaciju kinaze, i indikacije za njih
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
KR102237799B1 (ko) 2012-11-14 2021-04-08 더블유.알. 그레이스 앤드 캄파니-콘. 생물학적 활성 물질 및 비-정렬된 무기 산화물을 함유하는 조성물
GR1008554B (el) * 2014-06-12 2015-09-03 ΦΑΡΜΑΤΕΝ ΑΝΩΝΥΜΟΣ ΒΙΟΜΗΧΑΝΙΚΗ ΚΑΙ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΕΙΑ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΙΑΤΡΙΚΩΝ ΚΑΙ ΚΑΛΛΥΝΤΙΚΩΝ ΠΡΟΪΟΝΤΩΝ με δ.τ. ΦΑΡΜΑΤΕΝ, Φαρμακευτικο σκευασμα περιεχον εναν αντιμυκητιασικο παραγοντα τριaζολης και μεθοδος για την παρασκευη αυτου
CN104069500A (zh) * 2014-06-20 2014-10-01 湖南天地恒一制药有限公司 一种包含乐卡地平的药物组合物
CN105168165B (zh) * 2015-08-28 2018-06-26 江苏福邦药业有限公司 一种盐酸乐卡地平片及其制备方法
WO2018004379A1 (ru) * 2016-07-01 2018-01-04 Общество С Ограниченной Ответственностью "Гиостин" Средство в виде капсулы для лечения заболеваний суставов
CN114533686B (zh) * 2022-02-15 2023-10-20 湖南普道医药技术有限公司 一种二氢吡啶类药物的口服固体制剂及其制备方法
KR20240040407A (ko) * 2022-09-21 2024-03-28 주식회사 종근당 사쿠비트릴ㆍ발사르탄 칼슘염을 포함하는 약제학적 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3720757A1 (de) * 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
US5209933A (en) * 1990-01-10 1993-05-11 Syntex (U.S.A.) Inc. Long acting calcium channel blocker composition
GB9025251D0 (en) * 1990-11-20 1991-01-02 Solomon Montague C Nifedipine dosage forms
BR9903490A (pt) * 1998-12-15 2000-09-26 Oscar Gold Processo para a preparação de composições farmacêuticas de liberação programada contendo nimodipine, que permitem a liberação gradual e a manuntenção da ação terapeutica
DE19944803A1 (de) * 1999-09-20 2001-03-29 Bayer Ag Kombination von Dihydropyridinverbindungen und HMG-CoA-Reduktase-Inhibitoren und ihre Verwendung in Arzneimitteln
US20040185097A1 (en) * 2003-01-31 2004-09-23 Glenmark Pharmaceuticals Ltd. Controlled release modifying complex and pharmaceutical compositions thereof
WO2005053689A2 (en) * 2003-12-01 2005-06-16 Lifecycle Pharma A/S Pharmaceutical compositions comprising lercanidipine
UA89177C2 (ru) * 2003-12-01 2010-01-11 Рекордати Айрленд Лимитед Фармацевтическая композиция с контролируемым высвобождением, которая содержит лерканидипин
AU2007291509B2 (en) * 2006-08-30 2013-05-02 Jagotec Ag Controlled release oral dosage formulations comprising a core and one or more barrier layers
WO2008068777A2 (en) * 2006-12-06 2008-06-12 Torrent Pharmaceuticals Limited Stable lercanidipine formulation
EA021645B1 (ru) * 2007-07-23 2015-08-31 Фарматен С.А. Твердая дозированная форма в виде таблетки и способ её приготовления

Also Published As

Publication number Publication date
MX2010000801A (es) 2010-07-05
NZ582690A (en) 2011-12-22
ES2537063T3 (es) 2015-06-02
EA021645B1 (ru) 2015-08-31
JP5769963B2 (ja) 2015-08-26
EP2170295B1 (en) 2015-04-22
CR11285A (es) 2010-04-27
WO2009013306A1 (en) 2009-01-29
AU2007356942A1 (en) 2009-01-29
AU2008280106B2 (en) 2014-03-20
AU2007356942B2 (en) 2011-12-15
MY153857A (en) 2015-03-31
EA201000220A1 (ru) 2010-08-30
KR101512404B1 (ko) 2015-04-21
WO2009012791A1 (en) 2009-01-29
EP2180883B1 (en) 2017-01-11
ZA201001176B (en) 2010-11-24
KR20100045456A (ko) 2010-05-03
UA99136C2 (ru) 2012-07-25
CA2691752C (en) 2016-01-26
MX2010000856A (es) 2010-04-30
JP2010534211A (ja) 2010-11-04
UA97161C2 (ru) 2012-01-10
TN2010000011A1 (en) 2011-09-26
ZA201000586B (en) 2011-03-30
ES2622495T3 (es) 2017-07-06
TN2010000022A1 (en) 2011-09-26
BRPI0721883A2 (pt) 2014-02-18
AU2008280106A2 (en) 2010-02-25
EP2180883A1 (en) 2010-05-05
CN101801347A (zh) 2010-08-11
AU2008280106A1 (en) 2009-01-29
KR20100047848A (ko) 2010-05-10
EA019614B1 (ru) 2014-05-30
KR101632079B1 (ko) 2016-06-20
EP2170295A1 (en) 2010-04-07
ECSP109984A (es) 2010-04-30
MA31684B1 (fr) 2010-09-01
CN101784260A (zh) 2010-07-21
AU2008280106B9 (en) 2014-08-07
BRPI0814666A2 (pt) 2017-05-09
CA2693233A1 (en) 2009-01-29
NZ582648A (en) 2012-06-29
EA201070160A1 (ru) 2010-06-30
CA2691752A1 (en) 2009-01-29
JP2010534220A (ja) 2010-11-04
CN103976968A (zh) 2014-08-13

Similar Documents

Publication Publication Date Title
CO6290639A2 (es) Composicion farmaceutica mejorada que contiene dihidropiridina antagonista del canal de calcio y el metodo para su preparacion
CR11137A (es) Valvulas prosteticas de corazon
EA201391000A1 (ru) Индольные соединения или их аналоги, полезные для лечения возрастной макулярной дегенерации (amd)
TN2014000030A1 (en) Tetrahydropyrido-pyridine and tetrahydropyrido-pyrimidine compounds and use thereof as c5a receptor modulators
CL2013000713A1 (es) Compuestos pirazin-2-cabonil-imino-1,3,8-triaza-espiro-[4.5]-decan-sustituidos, bloqueadores del canal de sodio epitelial (enac); composicion farmaceutica que los incluye; metodo de prevencion o tratamiento; y su uso para tratar una enfermedad o condicion mediada por el bloqueo del canal de sodio epitelial.
CR20110110A (es) Composicion farmaceutica
EA201001847A1 (ru) Соединения и композиции, применяемые для лечения малярии
BR112012008485A2 (pt) composto, formulação farmacêutica, uso de um composto, processo para a fabricação do composto de formula e compostos, processos, formulações e usos
EA201200098A1 (ru) Конденсированные имидазолы и содержащие их композиции, предназначенные для лечения паразитарных заболеваний, таких как, например, малярия
WO2010111640A3 (en) Anti-influenza formulations and methods
CL2018001510A1 (es) Composición farmacéutica que comprende un potente inhibidor de urat1
EA201200616A1 (ru) Производные 2-оксо-1-пирролидинилимидазотиадиазола
CR20110209A (es) Composición farmacéutica sólida
EA201101118A1 (ru) Фармацевтические композиции, включающие производные 2-оксо-1-пирролидина
AR128459A2 (es) Composición farmacéutica sólida comprimida por rodillo y el proceso para su fabricación
BR122020011180B8 (pt) formulações injetáveis de compostos de tetraciclina
BR122016006880B8 (pt) forma de dosagem contendo pantoprazol como ingrediente ativo
ECSP077263A (es)
BR112018068370A2 (pt) composição farmacêutica em dose fixa contendo amlodipina, candesartan cilexetil e hidroclorotiazida para o tratamento de hipertensão
TR200909785A1 (tr) Aktif ajan olarak sefdinir içeren farmasötik kompozisyonlar.
CL2017002649A1 (es) Gránulos de monensina dispersables en agua por granulación húmeda.
WO2010070057A3 (en) Precompacted fast-disintegrating formulations of compounds with a low oral bioavailability
TR201009166A2 (tr) Sefdinir içeren farmasötik bileşim için üretim yöntemi
IN2013MU02442A (es)
EA201300160A1 (ru) 2,3,5-тризамещенные тиофены и их применение

Legal Events

Date Code Title Description
FC Application refused