UA80881C2 - New polymorphs of olanzapine hydrochloride - Google Patents
New polymorphs of olanzapine hydrochlorideInfo
- Publication number
- UA80881C2 UA80881C2 UAA200510999A UAA200510999A UA80881C2 UA 80881 C2 UA80881 C2 UA 80881C2 UA A200510999 A UAA200510999 A UA A200510999A UA A200510999 A UAA200510999 A UA A200510999A UA 80881 C2 UA80881 C2 UA 80881C2
- Authority
- UA
- Ukraine
- Prior art keywords
- new polymorphs
- new
- hydrochloride
- olanzapine
- olanzapine hydrochloride
- Prior art date
Links
- MFURKUWVJOJUHP-UHFFFAOYSA-N 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine hydrochloride Chemical compound Cl.C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 MFURKUWVJOJUHP-UHFFFAOYSA-N 0.000 title abstract 2
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0301082A HU226410B1 (en) | 2003-04-22 | 2003-04-22 | Novel polymorphous forms of olanzapine hydrochlorides, process for producing them, use thereof and pharmaceutical compositions containing them |
| PCT/HU2004/000042 WO2004094433A1 (en) | 2003-04-22 | 2004-04-22 | New polymorphs of olanzapine hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA80881C2 true UA80881C2 (en) | 2007-11-12 |
Family
ID=89981318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200510999A UA80881C2 (en) | 2003-04-22 | 2004-04-22 | New polymorphs of olanzapine hydrochloride |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7951798B2 (da) |
| EP (1) | EP1620439B1 (da) |
| JP (1) | JP4763594B2 (da) |
| KR (1) | KR20060004954A (da) |
| CN (2) | CN101468999B (da) |
| AT (1) | ATE401332T1 (da) |
| AU (1) | AU2004232544B2 (da) |
| BG (1) | BG109361A (da) |
| CA (1) | CA2522734C (da) |
| CZ (1) | CZ2005684A3 (da) |
| DE (1) | DE602004015096D1 (da) |
| DK (1) | DK1620439T3 (da) |
| EA (1) | EA008376B1 (da) |
| ES (1) | ES2310728T3 (da) |
| HR (1) | HRP20080479T3 (da) |
| HU (1) | HU226410B1 (da) |
| IL (1) | IL171522A (da) |
| PL (2) | PL378061A1 (da) |
| PT (1) | PT1620439E (da) |
| SI (1) | SI1620439T1 (da) |
| SK (1) | SK50942005A3 (da) |
| UA (1) | UA80881C2 (da) |
| WO (1) | WO2004094433A1 (da) |
| ZA (1) | ZA200508936B (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1575962A1 (en) * | 2002-12-24 | 2005-09-21 | Teva Pharmaceutical Industries Limited | Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms |
| SI21850A (sl) * | 2004-07-28 | 2006-02-28 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Soli olanzapina in njihova pretvorba v prosto bazo olanzapina |
| JP5324098B2 (ja) * | 2004-11-16 | 2013-10-23 | アルケルメス ファーマ アイルランド リミテッド | 注射可能なナノ粒子のオランザピン製剤 |
| HUP0501046A2 (en) | 2005-11-11 | 2007-08-28 | Egis Gyogyszergyar Nyilvanosan | Process for the preparation of olanzapine |
| KR20150081370A (ko) | 2006-07-10 | 2015-07-13 | 파이온 유케이 리미티드 | 속효형 벤조디아제핀 염 및 이의 중합체 형태 |
| WO2008151430A1 (en) * | 2007-06-14 | 2008-12-18 | Apotex Pharmachem Inc. | Novel processes to form-i of olanzapine |
| US20090286294A1 (en) * | 2008-04-04 | 2009-11-19 | University Of Massachusetts | Methods and Compositions for Improving the Production of Fuels in Microorganisms |
| EP2450039A1 (en) | 2010-11-08 | 2012-05-09 | PAION UK Ltd. | Dosing regimen for sedation with CNS 7056 (Remimazolam) |
| MX341132B (es) * | 2011-07-08 | 2016-08-09 | Lilly Co Eli | Compuesto (tieno [2-3-b] [1,5] benzoxazepin-4-il) piperazin-1-ilo como agonista h1 inversos/antagonistas 5-ht2a de actividad doble. |
| HUE037363T2 (hu) * | 2013-01-14 | 2018-08-28 | Lilly Co Eli | Kettõs aktivitású H1 inverz agonista/5-HT2A antagonista (tieno[2,3-b][1,5]-benzoxazepin-4-il)piperazin-1-il vegyületek |
| AR094963A1 (es) | 2013-03-04 | 2015-09-09 | Ono Pharmaceutical Co | Reacción de oxidación excelente en el índice de conversión |
| KR101489062B1 (ko) * | 2013-03-28 | 2015-02-02 | 동아에스티 주식회사 | 고순도의 올란자핀 및 이의 결정형 ii의 제조방법 |
| JP6940866B2 (ja) * | 2017-06-21 | 2021-09-29 | 国立研究開発法人情報通信研究機構 | 半導体光デバイス、半導体光源、光集積回路、及び半導体光デバイスの製造方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5229382A (en) * | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
| GB9009229D0 (en) | 1990-04-25 | 1990-06-20 | Lilly Industries Ltd | Pharmaceutical compounds |
| US6169084B1 (en) * | 1997-09-30 | 2001-01-02 | Eli Lilly And Company | 2-methyl-thieno-benzodiazepine formulation |
| DE69917663T2 (de) | 1998-09-30 | 2005-05-25 | Eli Lilly And Co., Indianapolis | 2-methyl-thieno-benzodiazepin-formulierung |
| UA80095C2 (en) | 2001-07-20 | 2007-08-27 | Lilly Co Eli | 2 methyl-thieno-benzodiazepine lyophilized formulation and method for the preparation thereof |
| WO2005070938A1 (en) * | 2004-01-27 | 2005-08-04 | Synthon B.V. | Stable salts of olanzapine |
-
2003
- 2003-04-22 HU HU0301082A patent/HU226410B1/hu not_active IP Right Cessation
-
2004
- 2004-04-22 CN CN2008101254419A patent/CN101468999B/zh not_active Expired - Fee Related
- 2004-04-22 SI SI200430885T patent/SI1620439T1/sl unknown
- 2004-04-22 PL PL378061A patent/PL378061A1/pl unknown
- 2004-04-22 PL PL04728854T patent/PL1620439T3/pl unknown
- 2004-04-22 AT AT04728854T patent/ATE401332T1/de active
- 2004-04-22 WO PCT/HU2004/000042 patent/WO2004094433A1/en active IP Right Grant
- 2004-04-22 US US10/553,908 patent/US7951798B2/en not_active Expired - Fee Related
- 2004-04-22 CN CNB2004800106655A patent/CN100471859C/zh not_active Expired - Fee Related
- 2004-04-22 UA UAA200510999A patent/UA80881C2/xx unknown
- 2004-04-22 PT PT04728854T patent/PT1620439E/pt unknown
- 2004-04-22 ES ES04728854T patent/ES2310728T3/es not_active Expired - Lifetime
- 2004-04-22 CZ CZ20050684A patent/CZ2005684A3/cs unknown
- 2004-04-22 EP EP04728854A patent/EP1620439B1/en not_active Expired - Lifetime
- 2004-04-22 ZA ZA200508936A patent/ZA200508936B/en unknown
- 2004-04-22 JP JP2006506249A patent/JP4763594B2/ja not_active Expired - Fee Related
- 2004-04-22 CA CA2522734A patent/CA2522734C/en not_active Expired - Fee Related
- 2004-04-22 KR KR1020057020041A patent/KR20060004954A/ko not_active Application Discontinuation
- 2004-04-22 DE DE602004015096T patent/DE602004015096D1/de not_active Expired - Lifetime
- 2004-04-22 EA EA200501633A patent/EA008376B1/ru not_active IP Right Cessation
- 2004-04-22 DK DK04728854T patent/DK1620439T3/da active
- 2004-04-22 SK SK5094-2005A patent/SK50942005A3/sk unknown
- 2004-04-22 AU AU2004232544A patent/AU2004232544B2/en not_active Ceased
-
2005
- 2005-10-20 IL IL171522A patent/IL171522A/en not_active IP Right Cessation
- 2005-11-22 BG BG109361A patent/BG109361A/bg unknown
-
2008
- 2008-09-26 HR HR20080479T patent/HRP20080479T3/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR002719A1 (es) | Forma ii polimorfa 2-metil-4-(4-metil-1-piperacinil)-10h-tieno[2,3-b]-[1,5] benzodiacepina(olanzapina) y formulaciones farmaceuticas que las contienen. | |
| UA80881C2 (en) | New polymorphs of olanzapine hydrochloride | |
| SI1513846T1 (sl) | Postopek za pripravo olanzapina form I | |
| BG108868A (en) | Polymorphs of clopidogrel hydrochloride and their use as antithrombic compounds | |
| IL176385A (en) | Compressed history of pyrrolo [34, -c] carbazol-1-van and pyrrolo [34, -c] carbazol-3,1-discussion and pharmaceutical preparations containing them | |
| HUP0203559A3 (en) | Polymorphic forms of sertraline hydrochloride, process for their preparation and pharmaceutical compositions containing them | |
| AU2003251247A1 (en) | Methods for preparation of olanzapine polymorphic form i | |
| WO2005090359A3 (en) | Synthesis of 2-methyl-4-(4-methyl-1-piperazinyl)-10h-thieno[2, 3-b][1,5]benzodiazepine and salts thereof | |
| MXPA04012200A (es) | Proceso para preparacion de olanzapina e intermediario de la misma. | |
| HUP0401157A2 (hu) | Liofilizált metil-tieno-benzodiazepin készítmény, előállítása és alkalmazása | |
| IS6437A (is) | Ný setin pýrazóló [4,3-e]díazepín lyfjasamsetningar sem innihalda þau, notkun sem læknandi afurðir og aðferðir við framleiðslu þeirra | |
| CA2395774A1 (en) | New polymorphic forms of olanzapine | |
| WO2003037903A8 (en) | Olanzapine dihydrate-ii a process for its preparation and use thereof | |
| SG113595A1 (en) | New benzo[b]chromeno-naphthyridin-7-one and pyrano[2',3':7,8] quino[2,3-b]quinoxalin-7-one compounds, process for their preparation and pharmaceutical compositions containing them | |
| WO2007087555A3 (en) | Novel polymorph 'form e ' of olanzapine (2-methyl-4- (4-methyl-1-piperazinyl) -10h-thieno [2, 3-b] [1, 5] benzodiazepine) and preparation of the anhydrous non-solvated crystalline polymorphic 'form i' of olanzapine from the polymorphic olanzapine 'form e' | |
| PL1963335T3 (pl) | Proces wytwarzania olanzapiny | |
| SG146431A1 (en) | New benzo[a]pyrano[3,2-h]acridin-7-one compounds, a process for their preparation and pharmaceutical compositions containing them | |
| SE0100295D0 (sv) | New compounds | |
| ECSP961694A (es) | Procedimeinto para preparar olanzapina (caso x - 9992m) | |
| DK1392698T3 (da) | Fremgangsmåde til fremstilling af 6-aryl-4H-s-triazolo-[3,4-c]thieno[2,3-e]-1,4-diazepiner | |
| HUP0600706A2 (en) | Tricyclic benzo[4,5]thieno-[2,3-d]pyrimidin-4-yl amines, pharmaceutically acceptable salts of them, process for their preparation and pharmaceutical compositions containing the same | |
| UA86772C2 (en) | Process for the preparation of the polymorph form of methyl (s)-(+)-(2-chlorophenyl)-2-(6,7-dihydro-4h-thieno[3,2-c]pyridine-5-yl-acetate hydrogensulfate |